Fitri Amelia

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The large multi-center international study, which was co-led by the Perelman School
of Medicine at the University of Pennsylvania in Philadelphia, calls into question
previous research that suggests light to moderate drinking may be good for the
heart. The researchers found that people with a particular gene consumed 17% less
alcohol per week, were less likely to binge drink, and were more likely to abstain
from alcohol altogether, than non-carriers.
The study defines light to moderate drinking as consuming 0.6 to 0.8 fluid ounces of
alcohol a day, or 17 to 23 ml, which is roughly what a 175 ml glass of wine contains.
The 155 researchers - from the UK, continental Europe, North America, and Australia
- pooled and analyzed data about links between drinking habits and heart health
from 56 epidemiological studies covering more than 260,000 people of European
descent.
They found that people with a particular gene consumed 17% less alcohol per week,
were less likely to binge drink, and were more likely to abstain from alcohol
altogether, than non- carriers.
These lower alcohol consumers typically had a 10% average reduced risk of
coronary heart disease, lower blood pressure and a lower body mass index (BMI).
The researchers conclude that reducing alcohol consumption across all levels of
consumption - even light to moderate drinking - is beneficial for heart health.
Co-lead author Michael Holmes, a research assistant professor in Perelman School of
Medicine's department of Transplant Surgery, says, "Contrary to what earlier reports
have shown, it now appears that any exposure to alcohol has a negative impact
upon heart health."
He explains how for some time, observational studies have suggested only heavy
drinking is bad for the heart, and that light drinking might even provide some
benefit, and this has led some people to believe moderate consumption is good for
their health, even lowering their risk of heart disease.
Even for light-to-moderate drinkers, reduced consumption may improve heart health
"However, what we're seeing with this new study, which uses an investigative
approach similar to a randomized clinical trial, is that reduced consumption of
alcohol, even for light-to-moderate drinkers, may lead to improved cardiovascular
health," says Prof. Holmes.
The focus of the study was investigating the heart health of people who carry a
particular version of the gene "alcohol dehydrogenase 1B" which codes for a protein
that helps to break down alcohol more quickly than in non-carriers.
The rapid breakdown causes nausea, facial flushing, and other symptoms, and is
linked to lower levels of alcohol consumption over time.
The team used the gene as an indicator of lower alcohol consumption, and from
there found the links between lower consumption and improved heart health.
Funds from the British Heart Foundation and the Medical Research Council in the UK
financed the study.
In April 2014, Medical News Today learned how neuroscientists at the University of
Utah are investigating a region of the brain that regulates how sensitive we are to
the negative effects of alcohol. Inactivating this region of the brain in rats led them
to drink more alcohol, at a faster pace.















Difficult Word

1. Roughly : Kira kira
The new horror film Annabelle was shown roughly 2 hours. I was frightened
watching that
2. Descent : Keturunan
European descent are more at risk of heart disease than Asian descent because of
their lifestyle and bad habit comsuming alcohol
3. Altogether : sama sekali
My brother never altogether called my parents since he traveled around the world 3
years ago
4. Approach : pendekatan
He never approached me before, all of a sudden after school yesterday, he declared
his love to me
5. Pace : kecepatan, langkah
We speed up our pace , so fast it looks like we were racing each other
6. Rapid : cepat
On the other hand, Indonesia only had four or five years to increase economic
rapidly under the command of Presiden SBY
7. Breakdown : kerusakan, gangguan
After she was break up with her boyfriend, Lina having a mental breakdown before
the exam, she gets C for english exam today
8. Contary : bertentangan, sebaliknya
It was a suicide case but all existing evidence indicates the contrary
9. Regulate : mengatur
Water is necessary to transport nutrients around the body, removes wastes,
maintain body temperatures and regulate metabolic processes in our bodies
10. Ounces : ons
The Butcher was always cheating, he reduces weight was as much as 30 ounces