DRUG STUDY

CLASSIFICATION MECHANISM
OF ACTION
INDICATION ADVERSE
REACTION
INTERACTION NURSING
CONSIDERATION
BRAND NAME:
Iselpin


GENERIC
NAME:
Sucralfate


DOSAGE:
tab q6
1 gm/tab
Cytoprotectives Forms a
complex by
binding with
positively
charged
proteins that
adheres to
ulcer site. This
selectively
forms a
protective coat
that protect
the lining
against peptic
acid, pepsin
and bile salts.
Duodenal and
Gastric ulcer

Chronic
gastritis
Constipation,
diarrhea,
nausea, gastric
discomfort,
indigestion,
dry mouth,
rash, pruritus,
back pain,
dizziness,
drowsiness
May decrease
binding of drug
to
gastrodoudenal
mucosa
imparing
effectiveness.
Separate doses
by 30 mins.
Reconstitute
drug before
instillation
through a
nasogastric tube.
Flush tube up
water to ensure
passage into
stomach

Monitor px for
severe persistent
constipation

Tell the px to
take meds on an
empty stomach,
1hr before each
meal.

CLASSIFICA
TION
MECHANISM OF
ACTION
INDICATION ADVERSE
REACTION
INTERACTION NURSING
CONSIDERATION
BRAND NAME:
Paracetamol


GENERIC
NAME:
Biogesic


DOSAGE:

Antibiotic
Antipyretic
Decrease fever
by inhibiting the
effects of
pyrogens on the
hypothalamic
action leading to
sweating and
vasodilation.

Relieves pain by
inhibiting
prostaglandin
synthesis at the
CNS but does
not have anti-
inflammation
action because
of its minimal
effect on
peripheral
prostaglandin
synthesis
Relief of fever,
minor aches
and pains


CONTRAINDIC
ATION:
Hypersensiti
vity to
acetaminop
hen or
phenacin

Long term
alcohol use
(may cause
hepatotoxici
ty)

Children <
3 years old
unless
directed by
a physician

Malnutrition

Thrombocyt
openia

Arthritic or
rheumatoid
conditions
Hepatic
Necrosis,
rash,
urticaria
Chronic
concurrent use
with NSAIDs,
including
aspirin may
increase the
risk of adverse
reactions

Diflunisal
increase
acetaminophen
blood vessels
and may
increases the
risk of
hepatotoxicity
with chronic
concurrent use.
Administer with a full
glass of water

May be taken with food
or on an empty stomach.

Advise patient to take
medication exactly as
directed and not to take
more than the
recommended amount

Avoid alcohol if taking
more than an occasional
1-2 doses

Use liquid form for
children and patients
who have difficulty
swallowing.

In children, dont exceed
five doses in 24 hours.

Advise patient that drug
is only for short term
use and to consult the
physician if giving to
children for longer than
5 days or adults for
affecting
children <
12 years old

longer than 10 days.

Advise patient or
caregiver that many over
the counter products
contain acetaminophen;
be aware of this when
calculating total daily
dose.

Warn patient that high
doses or unsupervised
long term use can cause
liver damage




CLASSIFICATI
ON
MECHANISM
OF ACTION
INDICATION ADVERSE
REACTION
CONTRAINDICA
TION
NURSING CONSIDERATION
BRAND NAME:
Lactated
Ringers
Solution with
5% Dextrose
(D5LR)
- Hypertonic
-
Nonpyrogenic
, parenteral
fluid,
electrolyte
and nutrient
replenisher
Hypertonic
Solutions are
those that have
an effective
osmolarity
greater than
the body fluids.
This pulls the
fluid into the
vascular by
osmosis
resulting in an
increase
vascular
volume. It
raises
intravascular
osmotic
pressure and
provides fluid,
electrolytes and
calories for
energy.

- Treatment
for persons
needing extra
calories who
cannot
tolerate fluid
overload.
- Treatment
of shock
-As a source
of water,
electrolytes
and calories
or as an
alkalinizing
agent
Allergic
reactions or
anaphylactoid
symptoms
such as
localized or
generalized
urticaria and
pruritis;
periorbital,
facial,
and/or laryng
eal edema,
coughing,
sneezing,
and/or
difficulty
with breathing
Administration of
sodium,
potassium,
calcium, chloride
or lactate could
be clinically
detrimental.

Severe metabolic
acidosis or
alkalosis, and in
severe liver
disease or anoxic
states which
affect lactate
metabolism.

Hypersensitivity
to corn products.

> Do not administer unless
solution is clear and
container is undamaged.
> Caution must be exercised
in the administration of
parenteral fluids, especially
those containing sodium
ions to patients receiving
corticosteroids or
corticotrophin.
>Solution containing acetate
should be used with caution
as excess administration
may result in metabolic
alkalosis.
>Solution containing
dextrose should be used
with caution in patients with
known subclinical or overt
diabetes mellitus.
> Discard unused portion.
> In very low birth weight
infants, excessive or rapid
administration of dextrose
injection may result in
increased serum osmolality
and possible intracerebral
hemorrhage.