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o f

S c i e n c e

SyllabuS

a n d

Yashwantrao Chavan
Maharashtra

Open University
Dnyangangotri, Near Gangapur Dam,
Nashik 422 222, India
Phone: 0253-2231714, 2231715, 2231473
Fax: 2231473/ 2231716
Email: sctech@ycmou.com
Website: http://www.ycmou.com/

Bio-Informatics Programme Curriculum

Te c h n o l o g y

Yashwantrao Chavan Mahara shtra Open University

S c h o o l

M.Sc.
in
Bio-Informatics

Page 1 of 14

Contents
1 Charts and Tables .............................................................................................................3
1.1 Bio-Informatics Programme Structure Charts ..............................................................3
1.2 Bio-Informatics Programmes Details ...........................................................................4
1.3 Bioinformatics Course Details ......................................................................................4
1.4 Course Distribution Chart ............................................................................................5
2 Syllabus ...........................................................................................................................6
2.1 Semester 08 ................................................................................................................6

2008, YCMOU. All Rights Reserved.


Price: Indian Rs 200/- or US$ 50/- only. Free Download of Internet Version.
Last Update: Saturday, June 27, 2009
Printed By:
Publisher: Registrar, YCMOU, Nashik 422 222, India.

Bio-Informatics Programme Curriculum

Page 2 of 14

1 Charts and Tables


1.1 Bio-Informatics Programme Structure Charts
1.1.1 For Odd Numbered Semesters
Mandatory
CS Month
Odd
Numbered
Semester
01

03

September

October

November

December

January

Course 1
4 CP, Theory
Course

Course 2
4 CP, Theory
Course
SBI012:
Communication
Skills

Course 3
4 CP, Theory
Course

Course 4
4 CP, Theory
Course
SBI014:
Environmental
Science

Course 5
4 CP, Practical or
Project-Work Course

SBI011:
Basic Biology
SBI031:
Basic
Biochemistry

SBI013:
Mathematics

SBI032:
General
Microbiology-I

SBI033:
Physiology

SBI034:
Metabolism

SBI015:
Lab Course
SBI035:
Lab Course

05

SBI051:
Basics of
Bioinformatics

SBI052:
Computer
Programming-I

SBI053:
DBMS-I

SBI054:
Introduction to
Molecular
Genetics

SBI055:
Lab Course

07

S08071:
Concepts in
Computing and
Basics of
Bioinformatics

SBI072:
Biological
Chemistry

SBI073:
Statistical
Techniques

SBI074:
Structural Biology

SBI075:
Lab Course

09

SBI093:
SBI094:
S09092:
Programming
Programming
SBI091:
Sequence-based Languages and
Languages and
Biochemistry of
Bioinformatics Softwarte Tools Softwarte Tools in
Metabolism
Approaches
in
Bioinformatics-II
Bioinformatics-I

SBI095:
Lab Course

1.1.2 For Even Numbered Semesters


Mandatory
CS Month
Even
Numbered
Semester

March

April

May

June

July

Course 2
4 CP, Theory
Course

Course 3
4 CP, Theory
Course

SBI022:
Basic Chemistry

SBI023:
Applied Physics

Course 4
4 CP, Theory
Course
SBI024:
Programming
Concepts

Course 5
4 CP, Practical or
Project-Work Course

02

Course 1
4 CP, Theory
Course
SBI021:
Basic Statistics

04

SBI041:
Cell Biology-I

SBI042:
Basic Biosciences

SBI043:
Biophysical
Techniques-I

SBI044:
Molecular Biology-I

SBI045:
Lab Course

06

08

10

SBI061:
Computational
Molecular
Biology

SBI062:
Computer
Programming-II

SBI081:
Genomics
Databases and
Applications

SBI082:
Genetic
Information
Flow and
Processing

SBI101:
Genetic
Engineering

SBI102:
Genetics and
Genomics

SBI064:
Cell Biology,
Genetics &
Immunology
SBI084:
SBI083:
Protein Structure
Programming in
Prediction and
Perl
Molecular
Modeling
SBI103:
SBI104:
Database
Research
Management
Methodology
Systems
SBI063:
DBMS-II

Bio-Informatics Programme Curriculum

SBI025:
Lab Course

SBI065
Lab Course

SBI085
Lab course
SBI105
Project

Page 3 of 14

1.2 Bio-Informatics Programmes Details


SN

Programme

For certification, student must confirm to


specified certification eligibility criteria and
following
courses
specified
for
the
respective programme must be successfully
completed

Post-Graduate Degree Programme


1

M.Sc. (Bio-Informatics)

All 20 courses at semester 07 to 10

Graduate Degree Programme


1

B.Sc. (Bio-Informatics)

All 30 courses at semester 01 to 06

1.3 Bioinformatics Course Details


CP: Credit Points
CST: Counseling Session Time
SST: Self-Study Time
Cat: Course Category from the below:

BS: Basic Science (Sem 01-02)

DB: Discipline Basic (Sem 03-04)

DC: Discipline Core (Sem 05-06)

SC: Specialization Courses (Sem 0710)


Type: Course Type from the below:

TH: Theory

PR: Practical

SP: Seminar or Project-Work


SN

Semester

Course
Code

CP

CST

SST

Marks

Cat

Type

SBI011

Basic Biology

40

120

100

BS

TH

SBI012

Communication Skill

40

120

100

BS

TH

SBI013

Mathematics

40

120

100

BS

TH

SBI014

Environmental Science

40

120

100

BS

TH

SBI015

Lab Course

80

120

100

BS

PR

SBI021

Basic Statistics

40

120

100

BS

TH

SBI022

Basic Chemistry

40

120

100

BS

TH

SBI023

Applied Physics

40

120

100

BS

TH

SBI024

Programming Concepts

40

120

100

BS

TH

10

SBI025

Lab Course

80

120

100

BS

PR

11

SBI031

Basic Biochemistry

40

120

100

DB

TH

SBI032

General Microbiology-I

40

120

100

DB

TH

SBI033

Physiology

40

120

100

DB

TH

SBI034

Metabolism

40

120

100

DB

TH

15

SBI035

Lab Course

80

120

100

DB

PR

16

SBI041

Cell Biology-I

40

120

100

DB

TH

SBI042

Basic Biosciences

40

120

100

DB

TH

SBI043

Biophysical Techniques-I

40

120

100

DB

TH

SBI044

Molecular Biology-I

40

120

100

DB

TH

20

SBI045

Lab Course

80

120

100

DB

PR

21

SBI051

Basics of Bioinformatics

40

120

100

DC

TH

SBI052

Computer Programming - I

40

120

100

DC

TH

SBI053

DBMS - I

40

120

100

DC

TH

SBI054

Introduction to Molecular Genetics

40

120

100

DC

TH

25

SBI055

Lab Course

80

120

100

DC

PR

26

SBI061

Computational Molecular Biology

40

120

100

DC

TH

SBI062

Computer Programming - II

40

120

100

DC

TH

SBI063

DBMS - II

40

120

100

DC

TH

3
4

8
9

12
13
14

17
18
19

22
23
24

27
28

5
6

Name

Bio-Informatics Programme Curriculum

Page 4 of 14

SN

Semester

Course
Code

29

Name

CP

CST

SST

Marks

Cat

Type
TH

SBI064

Cell Biology, Genetics &


Immunology

40

120

100

DC

30

SBI065

80

120

100

DC

PR

S08071

40

120

100

SC

TH

SBI072

Lab Course
Concepts in Computing and Basics
of Bioinformatics
Biological Chemistry

26

40

120

100

SC

TH

SBI073

Statistical Techniques

40

120

100

SC

TH

29

SBI074

Structural Biology

40

120

100

SC

TH

30

SBI075

Lab Course

80

120

100

SC

PR

26

SBI081

Genomics Databases & Applications

40

120

100

SC

TH

27

SBI082

Genetic Information Flow and


Processing

40

120

100

SC

TH

SBI083

Programming in Perl

40

120

100

SC

TH

SBI084

Protein Structure Prediction &


Molecular Modelling

40

120

100

SC

TH

30

SBI085

Lab Course

80

120

100

SC

PR

26

SBI091

Biochemistry of Metabolism

40

120

100

SC

TH

27

S09092

40

120

100

SC

TH

40

120

100

SC

TH

40

120

100

SC

TH

27
28

28
29

29

SBI094

30

SBI095

Sequence-based Bioinformatics
Approaches
Programming Languages and
Softwarte Tools in Bioinformatics-I
Programming Languages and
Softwarte Tools in Bioinformatics-II
Lab Course

80

120

100

SC

PR

26

SBI101

Genetic Engineering

40

120

100

SC

TH

27

SBI102

Genetics and Genomics

40

120

100

SC

TH

SBI103

Database Mnagement Systems

40

120

100

SC

TH

SBI104

Research Methodology

40

120

100

SC

TH

SBI105

Project

80

120

100

SC

SP

28

28
29

10

30

SBI093

1.4 Course Distribution Chart


1.4.1 As per Course Category
SN

Course Category

No of
Courses

Credit
Points

% of Credit
Points

Counseling
Hours

% of
Counseling
Hours

BS: Basic Science

10

40

20%

480

20%

DB: Discipline Basic

10

40

20%

480

20%

DC: Discipline Core

10

40

20%

480

20%

SC: Specialization Courses

20

80

40%

960

40%

Total

50

200

100%

2400

100%

No of
Courses

Credit
Points

% of Credit
Points

Counseling
Hours

% of
Counseling
Hours
67%

1.4.2 As per Course Type


SN

Course Type

TH: Theoretical

40

160

80%

1600

SB: Skill Based (PR and PW)

10

40

20%

800

33%

Total

50

200

100%

2400

100%

Bio-Informatics Programme Curriculum

Page 5 of 14

Syllabus

2.1 Semester 08
2.1.1 SBI081
Code

Course Name

Prog

Sem

CP

CST

SST

Marks

Type

Cat

BI

40

120

100

TH

SC

SBI081 Genomics Databases & Applications


Course Prerequisites:

Basic knowledge
databases

about

Course Objectives: After successful completion of this


biological course, student should be able to

Understand the role of Bioinformatics in the


genome sequencing, assembly, annotation and
post genomic analyses for gene identification,
structural
and
functional
elucidation
of
genomes, drug target identification etc.

Remarks:
UN

Name of Unit

CST

Evaluation Pattern

10

1 SAQ & 1 LAQ (in End Exam) and 5 MCQs


(in Self-Test) will be asked on these units.

Data Mining Tools

10

1 SAQ & 1 LAQ (in End Exam) and 5 MCQs


(in Self-Test) will be asked on these units.

Linking Genotype to Phenotype

10

1 SAQ & 1 LAQ (in End Exam) and 5 MCQs


(in Self-Test) will be asked on these units.

Applications of Genome Data

10

1 SAQ & 1 LAQ (in End Exam) and 5 MCQs


(in Self-Test) will be asked on these units.

Browsing Genomic Resources

UN

Detail Syllabus of the Unit

Browsing Genomic Resources:

CP

Genome Assembly overview


Related data resources (EST, STS, GSS, HSS) etc.
Genomic databases at EBI and NCBI
Genomic databases for human, mouse, yeast and other model organisms
Genomic databases for plant, microbial, parasite and viral genomes
Challenges in development of genomic databases & resources
2

Data Mining Tools:


Basic Aspects of Genome Annotation
Browsing genomic data using Ensembl (EBI) and Map Viewer (NCBI)
Prediction of ORFs and Genes; Gene Modeling,
Gene prediction algorithms for prokaryotes & eukaryotes
Prediction of Signal sequences (Promoters, Primers, splice sites, UTRs etc.), Operons

Linking Genotype to Phenotype:


Human & mouse genome: OMIM database
Identification of Disease Genes
Linking human genome data, OMIM database and SNP databases
Querying genomic data for various diseases
Identification of homologous genes: Orthologs & Paralogs
Linking genomic data in the context of metabolic pathways

Applications of Genome Data:

Bio-Informatics Programme Curriculum

Page 6 of 14

Genome based drug design


Genome based vaccine design
Microarray analysis & tools
Proteomics analysis & tools
Structural genomics
Functional genomics
Book Code Title,
Author,
ISBN of Original Edition

Details of
Chapters and Sections
Included in Syllabus

Edition Publisher,
Year
Price,
Order It Here

Text Books
SBI081-T1 Principles
of
Genome Included:
Analysis And Genomics (3rd Excluded:
Ed.) by Primrose, S.B. &
Twyman, R.M.

Blackwell

SBI081-T2 The Genome

VCH

Publishing

Company, 2003.

Ram S. Verma
ISBN 1-56081-043-2.
Reference Books
SBI081-R1 Genome

mapping
sequencing
By
Dunham,

and
Ian

Bio-Informatics Programme Curriculum

Horizon,

ISBN1-

898486-50-6.

Page 7 of 14

2.1.2 SBI082
Code

Course Name

SBI082 Genetic
Information
Processing

Flow

and

Course Prerequisites:

Knowledge of genetic material


prokaryotes and eukaryotes

Prog

Sem

CP

CST

SST

Marks

Type

Cat

BI

40

120

100

TH

SC

Course Objectives: After successful completion of this


in course, student should be able to

Understand concepts in gene organization,


transcription, translation and gene regulation

Appreciate Biotechnological implications of


recent developments in cloning and genome
sequencing

Remarks:
UN

Name of Unit

CP

Gene Expression

Genes and Enzymes

Genes RNA and Proteins

Gene
Expression
Analysis

UN

and

Methods

of

CST

Evaluation Pattern

10

1 SAQ & 1 LAQ (in End Exam) and 5 MCQs


(in Self-Test) will be asked on these units.

10

1 SAQ & 1 LAQ (in End Exam) and 5 MCQs


(in Self-Test) will be asked on these units.

10

1 SAQ & 1 LAQ (in End Exam) and 5 MCQs


(in Self-Test) will be asked on these units.

10

1 SAQ & 1 LAQ (in End Exam) and 5 MCQs


(in Self-Test) will be asked on these units.

Detail Syllabus of the Unit

Gene Expression: Prokaryotic gene expression, operons positive & negative regulation, sigma
factors. Initiation, elongation and termination of transcription template & enzyme properties

Genes and Enzymes: Eukaryotic RNA polymerase I, II & III transcribed genes, promoter &
regulatory sequences, transcription factors, Techniques foot printing, Reporter genes

Genes RNA and Proteins: Organization of globin, immunoglobulin, HLA, r RNA and 5 sRNA
genes. Processing of RNA and Proteins Transport and Stability
Gene Expression and Methods of Analysis: Stress & hormones regulated gene expression
Organization of human genome. RFLP, Fingerprinting. RAPDs, Microarrays, ESTs

Book Code Title,


Author,
ISBN of Original Edition

Details of
Chapters and Sections
Included in Syllabus

Edition Publisher,
Year
Price,
Order It Here

Text Books
SBI082-T1 Handbook
of
Biology
Rapley, Walker

Molecular Included:
Excluded:

SBI082-T2 Genetics from Genes to


Genomes
L. H. Hartwell, L. Hood, M.
L. Goldberg, A.E. Reynolds,
L. M. Silver & R. C. Veres,

Humane Press

McGraw-Hill, 2004

Reference Books
SBI082-R1 Molecular Biology
and Biotechnology
Rapley,Walker

Panima

SBI082-R2 Genes IX.


Benjamin Lewin

Jones
&
Bartlett
Publishers, 2007.

Bio-Informatics Programme Curriculum

Page 8 of 14

2.1.3 SBI083
Code

Course Name

SBI083 Programming in Perl


Course Prerequisites:

Knowledge
of
SBI062

SBI052,

Prog

Sem

CP

CST

SST

Marks

Type

Cat

BI

40

120

100

TH

SC

Course Objectives: After successful completion of this


SBI053, course, student should be able to

Understand organisation of biological data in


databases and parse data for processing

Remarks:
UN

Name of Unit

CP

Perl Introduction & Data Types

Control

Structures

&

Regular

Expressions

CST

Evaluation Pattern

10

1 SAQ & 1 LAQ (in End Exam) and 5 MCQs


(in Self-Test) will be asked on these units.

10

1 SAQ & 1 LAQ (in End Exam) and 5 MCQs


(in Self-Test) will be asked on these units.

Formats

10

1 SAQ & 1 LAQ (in End Exam) and 5 MCQs


(in Self-Test) will be asked on these units.

System, Network & DBM using Perl

10

1 SAQ & 1 LAQ (in End Exam) and 5 MCQs


(in Self-Test) will be asked on these units.

UN
1

Detail Syllabus of the Unit


Perl Introduction & Data Types:
Introduction & Overview:
What is Perl? Why use Perl in Bioinformatics? History of Perl, Availability, Support, Basic
Concepts
Scalar Data: What Is Scalar Data?, Numbers, Strings, Scalar Operators, Scalar Variables, Scalar
Operators and Functions
Arrays and List Data: What Is a List or Array? Literal Representation, Variables, Array Operators
and Functions, Scalar and List Context

Control Structures & Regular Expressions:


Control Structures: Statement Blocks
Hashes: What Is a Hash? Hash Variables, Literal Representation of a Hash, Hash Functions, Hash
Slices. Basic I/O
Regular Expressions: Concepts About Regular Expressions, Simple Uses of Regular Expressions,
Patterns, More on the Matching Operator, Substitutions, The split and join Functions
Subroutines: System and User Functions, The local Operator, Variable-length Parameter Lists,
Notes on Lexical Variables
Miscellaneous Control Structures:
Filehandles and File Tests: What Is a Filehandle? Opening and Closing a Filehandle, Using
Pathnames and Filenames, A Slight Diversion: die, Using Filehandles, The -x File Tests, The stat
Function
3

Formats:
What Is a Format? Defining a Format, Invoking a Format
Directory Access: Moving Around the Directory Tree, Globbing, Directory Handles, Opening and
Closing a Directory Handle, Reading a Directory Handle
File and Directory Manipulation
Process Management: Using system and exec, Using Backquotes,
Other Data Transformation: Finding a Substring, Extracting and Replacing a Substring
Formatting Data: Sorting, Transliteration

Bio-Informatics Programme Curriculum

Page 9 of 14

System, Network & DBM using Perl:


System Information: Getting User and Machine Information, Packing and Unpacking Binary Data
Getting Network Information
Database Manipulation: DBM Databases and DBM Hashes, Opening and Closing DBM Hashes,
Fixed-Length Random-Access Databases, Variable-Length (Text) Databases,

Win32 Database

Interfaces
CGI Programming: The CGI.pm Module, Your CGI Program in Context, Simplest CGI Program,
Passing Parameters via CGI, Perl and the Web
Object oriented perl: Introduction to modules, Creating Objects
Bioperl: Introduction, Installation procedures, Architecture, Uses of bioperl
Book Code Title,
Author,
ISBN of Original Edition

Details of
Chapters and Sections
Included in Syllabus

Edition Publisher,
Year
Price,
Order It Here

Text Books
SBI083-T1 Beginning

Perl

Bioinformatics

for Included:
Excluded:

O-Reilly

James Tisdall,
SBI083-T2 Developing

Bioinformatics

O-Reilly

Computer Skills
Cynthia

Gibas,

Per

Jambeck,
SBI083-T3 Programming the Perl DBI
Alligator

Descartes,

O-Reilly

Tim

Bunce,
Reference Books
SBI083-R1 Advanced Perl Programming

O-Reilly

Sriram Srinivasan

Bio-Informatics Programme Curriculum

Page 10 of 14

2.1.4 SBI084
Code

Course Name

SBI084 Protein

Structure

Prediction

Prog

Sem

CP

CST

SST

Marks

Type

Cat

BI

40

120

100

TH

SC

&

Molecular Modeling
Course Prerequisites:

Knowledge of
SBI074

SBI051,

SBI071

Course Objectives: After successful completion of this


& course, student should be able to

Understanding
the
levels
of
structure
organization of macromolecules and related
methods of structure determination

Understand and use various methods of 2D and


3D structure prediction

Understand
the
interaction
between
macromolecules

Remarks:
UN

Name of Unit

CP

Protein Purification

Qualitative
and
Evaluation of Protein

Exploring proteins

Prediction of Protein Structure

UN
1

Quantitative

CST

Evaluation Pattern

10

1 SAQ & 1 LAQ (in End Exam) and 5 MCQs


(in Self-Test) will be asked on these units.

10

1 SAQ & 1 LAQ (in End Exam) and 5 MCQs


(in Self-Test) will be asked on these units.

10

1 SAQ & 1 LAQ (in End Exam) and 5 MCQs


(in Self-Test) will be asked on these units.

10

1 SAQ & 1 LAQ (in End Exam) and 5 MCQs


(in Self-Test) will be asked on these units.

Detail Syllabus of the Unit


Protein Purification:
Basics of protein purification, differential centrifugation, salting out, dialysis, gel filtration and
ion exchange chromatography, affinity chromatography, HPLC, gel electrophoresis, isoelectric
focusing, two dimensional electrophoresis.

Qualitative and Quantitative Evaluation of Protein:


Ultracentrifugation,

Mass

spectroscopy

MALTDI-TOF,

peptide

mass

fingerprinting,

eman

degradation, protein sequencing, automated soild phase peptide synthesis, NMr spectroscopy.
3

Exploring proteins:
Databases:, NDB & CCSD
Calculation of conformational energy for bio-macromolecules
Molecular Mechanics & Molecular Dynamics of Oligopeptides, Proteins, Nucleotides and small
Molecules
Mechanics and dynamics of bio-macromolecules
Simulation of molecular mechanics and dynamics
Simulations of Free Energy changes
Force fields
Molecular interactions of
Protein Protein
Protein DNA
Protein carbohydrate
DNA small molecules etc.

Prediction of Protein Structure:


Prediction of Secondary Structure using Chou & Fasman, GOR series, PHD, PSSM etc.

Bio-Informatics Programme Curriculum

Page 11 of 14

Metaservers
Tertiary structures of Proteins using homology modeling
Evaluation of structure using Procheck, ProsaII etc.
Databases & servers for modeling
Approaches based on Neural; networks, genetic algorithms & machine learning methods
Fold recognition, threading
Methods to predict three dimensional structures of nucleic acids, rRNA
CASP, CFASP experiments
Book Code Title,
Author,
ISBN of Original Edition

Details of
Chapters and Sections
Included in Syllabus

Edition Publisher,
Year
Price,
Order It Here

Text Books
SBI084-T1 Proteins:

And Included:
Properties Excluded:

Structure

Molecular
Creighton, T.E.
SBI084-T2 Protein

Folding,.

New
York.
W.
H.
Freeman and Company,
1992

structure

New
York.
W.
H.
Freeman and Company,
1996

Creighton,T.
SBI084-T3 Protein
prediction:

practical

approach, Sternberg, M.J.E.


SBI084-T4 Molecular
principles

Second New
York.
W.
H.
Edition Freeman and Company,
1993.

modelling:
and

applications

Leach. A. R.
Reference Books
SBI084-R1 Structural
Methods

Bioinformatics
of

Wiley-Liss, 2003.

biochemical

Analysis V. 44 by Philip E.
Bourne

(Editor),

Helge

Weissig (Editor)

Bio-Informatics Programme Curriculum

Page 12 of 14

2.1.5 SBI085
Code

Course Name

Prog

Sem

CP

CST

SST

Marks

Type

Cat

BI

80

120

100

PR

SC

SBI085 Lab. Course

Course Prerequisites:
Course Objectives: After successful completion of this

Knowledge of list all 4 courses in this course, student should be able to


sem

Perform
practical
related
to
Genomic
databases, Structural Bioinformatics, GIFP and
Perl.
Special Note: Study Centers should conduct any 20 activities out of total 24 activities given in the
list. Students are expected to perform all activities mentioned in each experiment and maintain the upto-date journal and get certified from the lab instructor.
UN
1

Detail Syllabus of the Unit


Browsing Genomic databases using MapViewer & ensembl, viewing genetic, linkage maps for
human and other model organisms.

Browsing Human genome data, OMIM, SNP databases to understand genetic and metabolic
disorders at least 2 each

Browsing genomic resources for plant, yeast genomes

Browsing resources for microbial and viral genomes

Mining genomic data to identify genomic features: codon usage, repeats, reversals,
Homologous regions, operon structures, syntenic regions, horizontal gene transfer

Gene prediction algorithms for Prokaryotes (at least 2)

Gene prediction algorithms for Eukaryotes (at least 2)

Structural databases: revise pdb, ndb, ccsd,

Evaluation of 3D structure of proteins:


Procheck, Ramachandran plot, ProsaII plot

10

Explore: Derived databases of structures: DSSP, FSSP, CATH & SCOP

11

Prediction of secondary structures of proteins: at least 3 methods for 3 proteins

12

Prediction of Tertiary structure fo proteins: SwissModel and Modeller

13

Exploring metaservers for 2D and 3D structure prediction


Calculation of MCC & rmsd

14

Identifying fold of proteins


Use of threading servers: Phyre etc

15

Energy minimisation & geometry optimization for proteins & peptides

16

Using servers for function annotations: Evolutionary trace method etc.

17

Perl assignments: 17-24


Finding restriction Sites in given nucleotide sequence

18

Finding GI number for a Given Accession Number

19

Finding restriction Sites in given nucleotide sequence

20

Reading

Feature

table

and

extraction

of

sequence

position

and

feature

information

for

biomacromolecules.
21

Conversion of sequence formats

22

Parsing PDB file to populate tables in a database

23

Finding Molecular weight given the Molecular formulae. Ex: C 6 H 1 2 O 6

24

Making Phylogenetic tree of given sequences by using ClustalW and PHYLIP

Bio-Informatics Programme Curriculum

Page 13 of 14

Book Code Title,


Author,
ISBN of Original Edition

Details of
Chapters and Sections
Included in Syllabus

Edition Publisher,
Year
Price,
Order It Here

Text Books
SBI085-T1 Bioinformatics
A beginners Guide
Claverie, Notredame

Included:
Excluded:

SBI085-T2 Programming the Perl DBI


by Alligator Descartes, Tim
Bunce,

Willey

O-Reilly.

Reference Books
SBI085-R1 Bioinformatics
C.S.V. Murthy

Bio-Informatics Programme Curriculum

Himalaya
House

Publishing

Page 14 of 14

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