Rasoushadhis in Arbuda

RASAOUSHADHIS AND
BHASMAS IN THE
MANAGEMENT OF ARBUDA
DR. SANTHOSH B
DEPT. OF RASASHASTRA
Rasoushadhis and bhasmas used in Arbuda

- Dr. Santhosh B
Objectives
To understand the samprapti of Arbuda
To know different treatment modalities

To know where we can use rasoushadhis

- Dr. Santhosh B
Derivation
Derived from the root Arb with suffix Ena and
along with Nd
Destroy particularly the Mamsa Dhatu.
Denotes the fleshy out growths

- Dr. Santhosh B
Cancer
Dervied from Greek word
Karkinosmeaning Crab.
Appearance of large prominent veins
surrounding the growth, encircled the mass
like claws of a crab.

- Dr. Santhosh B
Definition
Large Glandular enlargement
A growth of new cells which proliferate

without relation to needs of body - Tumour
Types - Benign
- Malignant
- Dr. Santhosh B
Mechanism of
Carcinogenesis
- Dr. Santhosh B
Initiation
A single brief exposure to a carcinogen
induces changes in the tissue
The nature of the structural alterations in
initiated cell is diverse
Chemicals and ultra violet radiations directly

alter DNA structure
- Dr. Santhosh B
Promotion
Ability of a compound to induce an area of

proliferation in initiated tissue and stimulate
tumour formation
Dietary fat has been implicated as a tumour
promoter in the development of colon cancer

- Dr. Santhosh B
Progression
Usually refers to the later stage of tumour cell
evolution that are irreversible
Once the tumour develops, individual traits
such as hormone responsiveness, growth rate,
histologic type and invasiveness, function as
independent variables capable of progression

- Dr. Santhosh B
10
Metastasis
Active process consisting of 3 stages
attachment of cells to extra-cellular matrix
local degradation of extra-cellular matrix
locomotion through the locally degraded matrix
The spread of tumour from a primary lesion to a

distant site is a major cause of morbidity and mortality
Once the tumour cell has migrated to a metastatic site,
additional metastatic foci may occur by repetition of
these types
- Dr. Santhosh B
11
Mechanism of Invasion & Metastasis

Metastasis, the establishment of tumour cells at
distant sites in the body, is the hallmark of cancer
Tumour cells must acquire the ability to :
Invade stroma
Stimulate neoangiogenesis
Transgress stroma
Invade vessel walls
Extravasate into the extra vascular environment
Grow in a new microenvironment to establish
metastasis
- Dr. Santhosh B
12
Stem Cell
Initiation event
Initiated Cell
Promotion event
Pre Cancer Cell
Conversion event
Cancer Cell
Progression event
- Dr. Santhosh B
Metastatic Cell
13
Sushruta
uiSr qxqxM c S l
xlSwr qS MTluq ll
ui uaji i zT l
Muliri aljUi mS ll
Su. Ni. 11

- Dr. Santhosh B
14
Charaka
um cir pwM
xMz zxh Saku uhuMixi
shotha chikitsa

- Dr. Santhosh B
15
Su. Ni. 11 / 13-15

amSz YucSu Sw xqqcNi qxqpmSwr
u xjU qlSe qWliqlsmqs cUuSkrmMq
Muli qxmcr i zT iSoS zxuS uSli
uil ml MTl cm
Ul qxl c qSx c
iri ixr c shl alj xqll xS puli
- Dr. Santhosh B
16
Sw mS kU xUxi xqm xcr aiximMq

xxuqi qxmhQ qxUUciqz uq
xuirex kU mSqxkrqiSkUiqM xri
UrmSumQiiui mhQpuSoSmQixi

- Dr. Santhosh B
17
qmWUSpUSi qx mS mMUi zTq

AuSl xlakqllruhqmMqzqmqqmcsrq
mSqxxr lUxr oRqiulqxmUrhxr
qxoS iuiSxkrq ......

- Dr. Santhosh B
18
CLASSIFICATION OF ARBUDA

- Dr. Santhosh B
19
AmM ?
MTkMiu
qSkMiu
SwxjUiu
ajl iw

- Dr. Santhosh B
20

- Dr. Santhosh B
21

- Dr. Santhosh B
22
SAMPRAPTI OF ARBUDA

- Dr. Santhosh B
23
Nija - Mamsahara
Nidana sevana
Agantuja - Mushtipraharadi
Sanchaya
Agnimandya
Dhatwagni mandya
Prasara
Prakopa
Dosha prakopa
Rakta & mamsa dushti
Sroto Dushti
Sthana Samshraya
Khavaigunya
Arbuda Mamsarbuda - Raktarbuda
Dwirarbuda - Adhyarbuda
- Dr. Santhosh B
Vyakti
Bheda
24
Dosha
SAMPRAPTI GHATAKA
: Kapha and Vata predominant
Dushya
:Mamsa, Meda and Rakta
Srotas
:Mamsa, Meda and Raktavaha
Sroto dushti
: Sanga and Sira granthi
Agni
: Jatharagni & Dhatwagni
Rogamarga
:Bahya
Udbhavsthana : Anywhere in the body

Adhisthana : Sixth layer of the Skin - Rohini
Pratyatma Linga: Mamso Pachaya Tu Shopham
- Dr. Santhosh B
25
Lung Cancer
A coronal CT scan
Showing malignant
cancer of the lung.
tumor
central pleural effusion
1 & 3 lungs
2 spine
4 ribs
5 aorta
6 spleen
7 & 8 kidneys
9 liver
- Dr. Santhosh B
26

- Dr. Santhosh B
27
AETIOLOGY
Genetics
Changes in lifestyle especially in diet and

regimen
Highly polluted environment

- Dr. Santhosh B
28
COMMON SITES
T
O
P
U
B
L
I
K
THYROID
ORAL
PROSTATE
UTERUS
BREAST
LUNGS
GIT
KIDNEY
- Dr. Santhosh B
29
BENIGN
MALIGNANT
BOUNDARIES
encapsulated or well
circumscribed
SIZEusually small
Poorly circumscribed &

irregular
Often large
SECONDARY
CHANGES occur less
often
PATTERNusually
resembles the tissue
More often
Often poor
resemblance
of origin closely
- Dr. Santhosh B
30
NUCLEOCYTOPLASMIC
RATIOnormal
FUNCTIONusually well
maintained
GROWTH RATEslow
LOCAL INVASIONoften
compresses the
surrounding tissues
without invading or
infiltrating them
METASTASISabsent
Increased
May be retained, lost
or abnormal
Rapid
Usually infiltrates the
adjacent tissues
Frequently present

- Dr. Santhosh B
31
STAGING IN CANCER
TNM staging
T tumour
N lymph node involvement
M metastasis

- Dr. Santhosh B
32
TNM CLASSIFICATION
T1
< OR = to 2 cm
T2
> Than 2 & = to 4 cm
T3
> Than 4 cm
T4
Adjacent structures
involved
Unilateral single node
> than 3 to 6 cm
N1

- Dr. Santhosh B
33
N2a
N2b
N2c
N3
M0
M1
bilateral single node >than

3 to 6 cm
unilateral multiple nodes <
or = to 6 cm
Bilateral or contralateral
nodes < or = to 6cm
Any node (s) > than 6cm
No detectable distant
metastasis
Distant metastasis present
- Dr. Santhosh B
34
Prognosis
Susrutha
Sadhya
Vataja
Pittaja
Kaphaja
Medoja
Asadhya
Mamsaja
Adyarbuda
Dvirarbuda
Raktaja
- Dr. Santhosh B
35
Treatment of Cancer
Specific
Supportive
Surgical Removal
Radiation Therapy
Chemotherapy
Blood Product
Transfusions
Indwelling Central
Catheters
Enteral And Para-enteral
Nutrition

- Dr. Santhosh B
36
Liposarcoma Medo arbuda

- Dr. Santhosh B
37

- Dr. Santhosh B
38
raUMU
aljwuqw Mui pwYzjmirq l
mYulq m xzkrUmrSuh pwe ll
ruU + uQ oe + alkM
aUaO M U
sm
qSl
alkzsuwkuQlapxqp xqhq l
MMsxUri smixoSkux ll
zsei
mjr
- Dr. Santhosh B
39
Vanagasena Arbuda chikitsa

erSkuimuqoS mcNlSp l
Ualpr SWm mSWuukeri ll
WUS sk mi aWkq qlzs l
qk maR smr qSoSWU mU ll
Liqu r MrSzw zMUoS l
- Dr. Santhosh B
40
Frequently Used Rasoushadhis
ApM pxq
zZuw pxq
iij pxq
WUM pxq
xuh pxq
iq pxq
US Ux
AoSWU Ux
- Dr. Santhosh B
41
Rasendra sara sangraha

UqohSMl rauWl mreri l

- Dr. Santhosh B
42
pUi pwer UMU

rauW mra :
AalkZmU mmO
AalMqU Ux (31)
AqU xlSU Ux
AMcM Ux
Al MqU Ux
AUar xaU Ux
ESr pxMU Ux
Eqzqp Ux
MlisW Ux
- Dr. Santhosh B
43
Main Drugs
mUS
alkM
uixlp

- Dr. Santhosh B
44
Roudra Rasa
References :
Rasendra sara sangrah

Rasa chandamshu
Rasa raja sundara
Bhruhannighantu ratnakara
Rasa kamadhenu
- Dr. Santhosh B
45
z xi xq alk q rqcir l
laussUxr qblS mllu ll
aqmmmsr q Sku mOssb l
si S Ux US aleqoS eri ll

- Dr. Santhosh B
46
AoSWU Ux
ihQsrMuwplaMlrosUx l
aq c Ux m mOmYuoSSei ll
( U. U. x. 24/136 )

- Dr. Santhosh B
47
ApM pxq
Puta 1 1000 ( AkMxrkM Tsq )
aUie mUqqqi uimrbl mblok

mzqie uwrqrwrqarq
osr xlak cSqMT Sml ziur ia
xMsaSWSurq xilSolk (U. U. x. )
- Dr. Santhosh B
48
xuurkWU Swzql u xlSml....

....x mhuukl .....( U. m. x. )
qirpi WUi xii xurql qipMq ( A. m)
xuUaWU urq eri rauWMq ( U. c)
Dose : 1 to 2 Ratti ( 1 ratti = 125 mg)

- Dr. Santhosh B
49
zZuw pxq
MTuiqrWU , osr , uwr , Uxrl -( Uxqi )
UxolkMU , xlak , Swbl , UxurMi

( U. U. x. 3/ 126)
Dose : 1/120 to 1/30 ratti
- Dr. Santhosh B
50
iij pxq
sZl, pSl, Uxrl, osr, cwr, qWqSWU mU
xMclMU lQl osMi mUq
( U. i. 21/129 )

- Dr. Santhosh B
51
WUM pxq
ArwrmSq Swrmzql xMsqrblq xilSolk
qirler Aqimqqu ue ( U. U. x. 4/32 )
xqi WUM....wQxluiq
rauW.... xui Uxrlq
....qWqSulzlq... mhQzjSUWU......
uwr qWrwrq..... osr Swblq....
( U. i. 23/27 )
Dose : 1/32 to 1/16 ratti

- Dr. Santhosh B
52
xuh pxq
Ux
ur
umM
ah
qkU Mwr i
zi
qkU
xxl , a , sZl , rauW ,
Uxrl , Swlzl , Arwrq ,
osr
Dose : to ratti
( A. M. 2/48 )
- Dr. Santhosh B
53
iq pxq
Ux - i Mwr
ur - Ewh
umM - qkU
ah - sZl, m MTmW
Uabli - Slq, r, mhQ, M,
(U. U. x. 5/46 )
- Dr. Santhosh B
54
Maggotification
Paste of Nishpava, Pinyaka, Kulatha, Mamsa,
Takra etc. are applied over arbuda to attract
flies. So that worms & parasites may be
produced and will consume the tissues of
Arbuda. ( Su. Chi. 18 / 37-39 )
Remnant unconsumed Arbuda should be done
Lekhana & Agnikarma.

- Dr. Santhosh B
55

- Dr. Santhosh B
56

- Dr. Santhosh B
57

- Dr. Santhosh B
58

- Dr. Santhosh B
59
Effect of rasayana : It effects the genesis of proper rasadi dhatus

It acts as an immuno-modulator
It acts at the physical and mental levels
- Dr. Santhosh B
60
Some important Rasayana prayogas

Bhallataka rasayana
Chitraka rasayana
Silajatu rasayana
Lashuna rasayana
Pippali rasayana
Hareetaki rasayana
Guggulu rasayana
- Dr. Santhosh B
61
Drugs having anti cancerous action

Aswagandha
Vinca rosea
Ananthamoola
Lashuna
Amalaki
Silajatu
Triphala
Guggulu
Guduchi
Kumari
Bhallataka
Chitraka
Haridra
Yavani
- Dr. Santhosh B
62
Discussion
Can we manage Arbuda without surgery, only
on Rasoushadhis ?

- Dr. Santhosh B
63
Conclusion
Understanding the samprapti of Arbuda is
prime requirement for planning the treatment
Granthi Arbuda are Chedya Vyadhi. So
Surgery is the best line of treatment
Chemotherapy and Radiation therapy cause

lot of side effects. So Rasayana therapy should
be adjoined
- Dr. Santhosh B
64

- Dr. Santhosh B
65
References
A. P. I. Text book of Medicine

Sushruta Samhita
Charaka Samhita
Rasa Ratna Samuchaya
Rasa Tarangini
Yogaratnakara
Bruhannighantu Ratnakara
Rasendra Sara Sangraha
Dr. Pradeep Shinde sirs collection of PPT
Jamnagar dissertation
Internet
- Dr. Santhosh B
66

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RASAOUSHADHIS AND

Rasoushadhis and bhasmas used in Arbuda

To know different treatment modalities

Rasoushadhis and bhasmas used in Arbuda

Rasoushadhis and bhasmas used in Arbuda

Rasoushadhis and bhasmas used in Arbuda

A growth of new cells which proliferate

Chemicals and ultra violet radiations directly

Ability of a compound to induce an area of

Rasoushadhis and bhasmas used in Arbuda

Rasoushadhis and bhasmas used in Arbuda

The spread of tumour from a primary lesion to a

Mechanism of Invasion & Metastasis

Rasoushadhis and bhasmas used in Arbuda

Rasoushadhis and bhasmas used in Arbuda

Su. Ni. 11 / 13-15

Sw mS kU xUxi xqm xcr aiximMq

Rasoushadhis and bhasmas used in Arbuda

qmWUSpUSi qx mS mMUi zTq

Rasoushadhis and bhasmas used in Arbuda

Rasoushadhis and bhasmas used in Arbuda

Rasoushadhis and bhasmas used in Arbuda

Rasoushadhis and bhasmas used in Arbuda

Rasoushadhis and bhasmas used in Arbuda

Rasoushadhis and bhasmas used in Arbuda

Rakta & mamsa dushti

:Mamsa, Meda and Rakta

:Mamsa, Meda and Raktavaha

: Sanga and Sira granthi

: Jatharagni & Dhatwagni

Udbhavsthana : Anywhere in the body

Rasoushadhis and bhasmas used in Arbuda

Changes in lifestyle especially in diet and

Rasoushadhis and bhasmas used in Arbuda

Poorly circumscribed &

Rasoushadhis and bhasmas used in Arbuda

Rasoushadhis and bhasmas used in Arbuda

> Than 2 & = to 4 cm

Rasoushadhis and bhasmas used in Arbuda

bilateral single node >than

Rasoushadhis and bhasmas used in Arbuda

Liposarcoma Medo arbuda

Rasoushadhis and bhasmas used in Arbuda

Rasoushadhis and bhasmas used in Arbuda

Vanagasena Arbuda chikitsa

Frequently Used Rasoushadhis

Rasendra sara sangraha

Rasoushadhis and bhasmas used in Arbuda

pUi pwer UMU

Rasoushadhis and bhasmas used in Arbuda

Rasendra sara sangrah

Rasoushadhis and bhasmas used in Arbuda

Rasoushadhis and bhasmas used in Arbuda

aUie mUqqqi uimrbl mblok

xuurkWU Swzql u xlSml....

Dose : 1 to 2 Ratti ( 1 ratti = 125 mg)

UxolkMU , xlak , Swbl , UxurMi

Rasoushadhis and bhasmas used in Arbuda

Dose : 1/32 to 1/16 ratti

Rasoushadhis and bhasmas used in Arbuda

Rasoushadhis and bhasmas used in Arbuda

Rasoushadhis and bhasmas used in Arbuda

Rasoushadhis and bhasmas used in Arbuda

Rasoushadhis and bhasmas used in Arbuda