Chapter 1

1.
2.
3.
4.
5.
6.
7.
8.
9.
10.
11.
12.
13.
14.
15.
16.
17.
18.
19.
20.

Tonofilaments (Nov 2007)

Fat necrosis (Nov 2007)
Cytoskeletal abnormalities (Nov 2006)
Apoptosis (Nov 2006, Feb 1997)
Role of free radicals in cell injury (Nov 2005, Oct 2003, Sep 1996, )
Theories of cellular ageing (Apr 2004)
Describe the genetic pathway of programmed cell death. Add a note on the role of
programmed cell death in the pathogenesis of disease. (Oct 2002)
Atrophy (May 2000)
Discuss irreversible cell injury in detail giving examples and add a note on apoptosis. (June
1999)
Descrobe briefly the structure of basement membrane and its alterations in diseased stages.
(Sep 1997)
Abnormal calcification.( Sep 1996)
Dystrophic calcification. (Mar 1996)
Intermediate filaments. (Sept 1994, DNB-95)
Fibrinoid necrosis. (Oct 1992)
Describe the pathology of reversible and irreversible cell injury. (Mar 1992)
Describe the importance of intracellular filaments in human disorders. (Aug 1985)
Lipofuscin.
Cellular responses to hypoxia. (Nov 2005)
Name the antioxidants. Discuss the role of various active radicals in the causation of injury to
the cells. Discuss the role of antioxidants in prevention of such injuries. (Aug 1984)
Nucleolar organizing regions. (DNB-95)

Chapter 2
1. Define Granuloma. Describe various giant cells. (DCP-Nov 2008)
2. Define inflammation. Discuss cellular events and chemical mediators of acute inflammation.
(DCP-June 2008, May 2001))
3. Describe in detail the cellular events in acute inflammation. (DCP Nov 2005)
4. Write short notes on giant cells. (DCP-Nov 2005)
5. Describe the role of chemokines in inflammation. (Nov 2008)
6. Describe the source ,derivation and functions of leucotrienes. (June2008)
7. Write short essay on the role of cells in inflammation. (Nov 2007)
8. Describe the plasma derived chemical mediators of inflammation. (Jun 2007)
9. Define and classify granuloma. Describe its pathogenesis and fate. (Jun 2007)
10. Write short notes on the role of endothelial cells in inflammation. (Nov 2006)
11. Describe the histology, immunochemistry, functions and the the role endothelial cells in
health and disease. (Jun 2007)
12. Acute phase reactants. (Nov 2006)
[1]

13. Chemokines and inflammation. (Oct 2003)

14. Discuss arachidonic acid metabolites and their role in inflammation. (Mar 2003)
15. Describe the functions of leucocytes in relation to inflammation and enumerate the various
clinical conditions due to leucocyte dysfunction. (Sept 2001, Feb 1997))
16. Describe chemokines. Discuss their role in health and disease. (Mar 2001)
17. Chemotaxis. (Dec 2000)
18. Cytokines. (Aug 1998, Feb 1994)
19. Endothelial leukocyte adhesion in inflammation. (Mar 1996)
20. Cells in chronic granulomatous inflammation. (Sept 1994)
21. Role of necrotic tissue in inflammation. (Oct 1992)
22. Sarcoidosis. (Mar 1992)
23. Discuss the role of chemical mediators in acute inflammation. (May 1988, Aug 1984)
24. Describe the various animal experiments which have helped to understand the dynamics of
inflammation. (Apr 1987)
25. Discuss the role of monocyte-macrophage system in health and disease. (Feb 1985)
26. Prostaglandins. (Mar 1985)
27. Interleukins. (Feb 1994)
28. Leucocyte function disorders. (Mar 2004)
29. Describe briefly the classification and laboratory investigations in neutrophil function
disorders. (Mar 2003)

Chapter 3
1. Discuss healing by first and second intention. Describe the factors influencing wound healing.
(DCP-Jun 2006)
2. Write short notes on adhesion molecules. (DCP-Nov 2005,Mar 2004))
3. Describe the role of cell adhesion molecules in health and disease. (Apr 2009)
4. Discuss the experimental aspects and recent advances in the phenomenon of repair. (Nov
2008)
5. Discuss the role of growth factors in wound healing. (Jun 2008)
6. Define and classify adhesion molecules and describe their role in pathology. (Jun 2007)
7. Describe the steps in the healing of fracture and its complications. (Jun 2007)
8. Mention most important growth factors and cytokines involved in tissue regeneration and
repair. What is their function? Discuss the signaling mechanisms in cell growth. (May 2006)
9. Growth factors. (Nov 2007, Nov 2006, Mar 2003)
10. Describe endothelial and leucocyte derived adhesion molecules and their role in
inflammation. (Apr 2005)
11. Describe the process of angiogenesis in detail. (Apr 2005)
12. Mechanism of wound healing. (Dec 2000)
13. Fibronectins. (Feb 1998)

[2]

14. Describe the composition of tissue matrix with emphasis on collagen. What are collagen
disorders? (Sep 1996)
15. Describe cell proliferation in health and disease. (Sep 1994)
16. Regeneration. (Mar 1992)
17. Stem cells. (Dec 1999)
18. Emerging applications of stem cell therapy. (Mar 2004)
19. Proliferation markers. (May 2001)
Chapter 4
1.
2.
3.
4.
5.
6.
7.
8.
9.
10.
11.
12.
13.
14.
15.
16.
17.
18.
19.
20.
21.
22.

Thrombogenesis. (Nov 2007)

Shock Lung. (Nov 2007)
Describe in detail Virchows triad. (May 2007)
Define and classify Infarct. Describe its morphology and fate. (May 2007)
Explain the role of endothelium in thrombosis and hemostasis. (Apr 2005)
Endothelial cells in health and disease. (Sep 2003, Sep 2002)
Cardiac thrombosis. (Mar 2004)
Discuss the pathogenesis and pathology of shock. (Mar 2003)
Thromboembolism. ( Mar 2002)
Discuss the recent concepts about shock. (May 2000, Apr 2005)
Define and classify shock. Add a note on cardiogenic shock. (Dec 1999)
Discuss the pathogenic mechanisms of septic shock. Describe the pathology of the organs
involved. (Aug 1998)
Discuss the pathogenesis of edema. (Mar 1996, Mar 1992)
Pulmonary embolism. (Sep 1995, DNB 1996)
Describe the pathophysiology and pathology of oligaemic shock. (Sep 1994)
Tissue plasminogen activator. (Mar 2003)
Chemical mediators of septic shock. (Feb 1997)
Nephrogenic edema. (Feb 1997, DNB Feb 1998)
Pathophysiology of septic shock. (DNB 1996)
Shock kidney. (DNB 1996)
Pathophysiology of cardiogenic shock. (DNB 1997)
Fate of thrombus. (DNB 1998)

Chapter 5
1.
2.
3.
4.
5.
6.
7.

Discuss molecular cytogenetics in modern pathology. (Apr 2009)

Discuss biochemical and molecular basis of single gene disorders. (DCP May 2007)
Describe the mendelian pattern of genetic inheritancewith examples. (May 2007)
Classify lysosomal storage disorders. Describe glycogen storage diseases. (Apr 2005)
Modification of PCR. (Sep 2003)
DNA repair genes. (Sep 2003)
Discuss the application of cytogenetics in diagnosis of disease. (Mar 2002)
[3]

8. Polymerase chain reaction. (Sep 2001)

9. Implications of genomic imprinting for human disease. (Sep 2001)
10. Write briefly on specific techniques and applications of diagnostic molecular pathology.
(Dec2000)
11. Chromosomal bonding techniques. (June 1999)
12. Ochronosis. (Sep 1997)
13. Describe briefly the various methods of DNA recombinant techniques and their diagnostic
applications in histopathology. (Feb 1997)
14. Klinefelter syndrome. (Sep 1996)
15. Molecular hybridization. (Mar 1996)
16. Lysosomal dysfunction. (Sep 1995)
17. Biochemical basis of mendelian disorders. (Sep 1995)
18. What are the indications and utility of cytogenetic studies? (Apr 1987)
19. Discuss clinical cytogenetics. (Feb 1985)
20. Glucose -6- phosphate deficiency. (Sep 2001)
21. Phenylketonuria. (Mar 1985)
22. Episomes. (Oct 1992)
23. Gene therapy. (Feb 1998, Apr 2005)
24. Discuss the current modalities of screening for genetic disorders. (Sep 2004)
25. Describe the medical applications of PCR. (Apr 2009)
Chapter 6
1. Discuss amyloidosis. (DCP Apr 2009)
2. Discuss the classification and pathogenesis of amyloidosis. (Sep 2001, Mar 1992, Nov 2005)
3. Describe the mechanisms involved in transplant rejection and discuss the methods of
increasing graft survival. (Jun 2008)
4. Describe the pathomechanisms and significance of type 2 hypersensitivity reactions with
examples. (May 2007)
5. Microscopic features of organ changes in secondary amyloidosis. (Nov 2008)
6. Describe the causes and mechanism that underlie the development of autoimmune diseases.
(Apr 2005)
7. Amyloidogenesis. (Mar 2004)
8. Autoimmune diseases. (Mar 2003)
9. Classify autoimmune diseases. Discuss the aetiopathogenesis and pathology of systemic lupus
erythematosus. (Sep 2002)
10. Histocompatibility antigens. (Mar 2002, Sep 2001)
11. Type 4 hypersensitivity antigen. (Dec 2000)
12. Primary immunodeficiency syndromes. (Aug 1998)
13. Discuss the aetiopathogensis of amyloidosis. Write briefly about the demonstration of
amyloid in tissues. (Feb 1998)
14. Local immune complex disease. (Feb 1998)
[4]

15.
16.
17.
18.
19.
20.
21.
22.
23.
24.
25.
26.
27.
28.

Immunological subsets of lymphocytes. (Sep 1997,Apr 1987)

Discuss HIV related attractions in immune function. (Sep 1995)
Electron microscope appearance of amyloidosis. (Oct 1992)
Mast cells. (Apr 1987)
Discuss leucocyte products in immunologically mediated inflammatory reactions. (Aug 1985)
Renal amyloidosis. (Mar 1985)
Discuss the T-cell and B-cell identification in the diagnosis of immuneproliferative disorders.
(Aug 1984)
Give an account of immunological markers and its diagnostic role of diseases. (Apr 1990)
Discuss the experimental production of amyloidosis. (Mar 1986)
Anticoagulant proteins. (Dec 1999)
Cell mediated immunity. (Jan 1999)
Antigen retrieval methods. (Jun 1999)
Pathology of transplant rejection. (Feb 1997)
What is HLA? What is its role in transplantation? Give a short description of laboratory
procedures for organ transplantation. (Aug 1984)

Chapter 7
1. P 53 gene
2. Describe tumour suppressor genes in detail. (Apr 2009, Nov 2005, Apr 2004, Aug 1998, Dec
1999)
3. Describe viral and microbial carcinogenesis. (Nov 2008)
4. Discuss the major chemical carcinogens and steps involved in chemical carcinogenesis. (Jun
2008)
5. Discuss Asbestos related neoplasia. (Apr 2009)
6. Discuss paraneoplastic syndrome and their implications. (Apr 2009, Sep 1994)
7. Viral oncogenes. (Nov 2007)
8. Define, classify and describe premalignant lesions. (May 2007)
9. Mechanism of metastasis. (Nov 2006)
10. Tobacco and neoplasia. (Nov 2006)
11. Carcinoid syndrome. (Nov 2006)
12. Proto oncogenes. (Nov 2005)
13. Systemic effects of cancer. (Nov 2005, May 2000)
14. Radiation induced oncogenesis. (Nov 2005)
15. Classify oncogenes. Describe their role in neoplasia. (Apr 2005)
16. HPV and neoplasia. (Sep 2003)
17. Flow cytometry. (Sep 2002, Sep 2001, June 2007, Nov 2006)
18. Tumour antigens. (Sep 1992)
19. Biology of tumour metastasis. (Mar 2002)
20. Discuss the recent concepts of carcinogenesis and the role of oncogenes in carcinogenesis.
(Sep 2001)
[5]

21.
22.
23.
24.
25.
26.
27.
28.
29.
30.
31.
32.
33.
34.
35.
36.
37.
38.
39.
40.
41.
42.

Telomerase and neoplasia. (2001)

Chromosomal aberrations in solid tumours. (May 2001, Sep 1995)
Tumour angiogenesis. (Dec 2000)
Discuss the role of various gene classes involved in cancer. (Feb 1998)
Discuss briefly the role of viruses in neoplasia. (Sep 1997, Mar 1992, Mar 1985)
Precancerous lesions. (Sep 1997)
Discuss experimental carcinogenesis. (Mar 1996)
Dysplasia. (Aug 1995)
Discuss oncogenes and cancer. (Oct 1992)
Discuss teratomas. (Apr 1990)
Discuss non-neoplastic and neoplastic proliferative disorders. (Mar 1986)
Discuss the connective tissue alterations in malignancy. (Feb 1985)
Discuss the hormone receptors in human neoplasia. (Feb 1985)
Explain the pathogenetic mechanisms of paraneoplastic syndromes. (1986)
Xeroderma pigmentosum. (Mar 1985)
Estrogen as a promoter of neoplasia. (Apr 1987)
Metastatic gene. (Nov 1997)
FISH technology. (Dec 2000)
Role of IHC in diagnosis or cancer. (Aug 1996)
DNA viruses and cancer. (DNB 1996)
Principles of screening tests for early diagnosis of disease. (DNB 1998)
Discuss the different modalities of approach to a case of metastatic cancer of unknown
primary.
43. Hypercalcemia in malignancy. (Dec 2000)
Chapter 8
1.
2.
3.
4.
5.
6.
7.
8.
9.
10.
11.
12.
13.
14.

Discuss the immunopathology and laboratory diagnosis of Leprosy. (Nov 2008)

Describe in detail immune pathogenesis of HIV disease. (Nov 2008)
Classify Leprosy and discuss the immunopatholgy of Leprosy. (Jun 2008)
Describe the opportunistic infections of AIDS and mention the neoplasms found in HIV
infection. (Jun 2008)
Non reactive tuberculosis. (Nov 2006)
Prions. (Nov 2006, May 2001)
Atypical Mycobacterial infections. (Nov 2005)
Infections resembling mycosis. (Mar 2004)
Herpes simplex and Herpes genitalis infection. (Mar 2002)
Spirochaetal infections. (Dec 1999, Sep 1995)
Chlamydial diseases. (Jun 1999)
Viral inclusions. (Feb 1998)
Common deep fungal infections. (Feb 1997)
Gas gangrene. (Oct 1992)
[6]

15.
16.
17.
18.
19.
20.
21.
22.
23.
24.
25.
26.
27.

Give an overview of the pathology of AIDS. (Apr 1990)

Histoid Leprosy. (Nov 2007)
Mucocutaneous manifestations of HIV infections. (Dec 2000)
Epstein Barr virus. (Dec 1999)
Toxoplasmosis. (Oct 1988)
Discuss the pathogenesis and pathology of Legionnaires disease. (Aug 1985)
Lyme disease. (Oct 1992)
Pathogenesis of cerebral malaria. (2001)
Immunology of malaria. (Nov 2006)
Hemoparasites and newer diagnostic modalities. (Nov 2005)
Discuss the pathology of campylobacter infections in humans. (Jun 2007)
Discuss the current concepts in the pathogenesis of AIDS. (Dec 2000)
What are the contributory factors to AIDS and which organs show maximum involvement.
(Aug 1998)
28. Discuss the diagnosis of AIDS. (Aug 1997)
Chapter 9
1. Discuss the pathology and pathogenesis of gauchers disease. (Jun 2008)
2. Describe the acute radiation injury and delayed complications caused by ionizing radiation.
(Jun 2008)
3. Obesity and disease. (Nov 2006)
4. Describe radiation induced tissue injury in detail. (Apr 2005.Apr 1987)
5. Biological effects of radiation. (Mar 2004, Sep 2001))
6. Vitamin A toxicity. (Feb 1998)
7. Injury by non-ionising radiations. (Dec 1999)
8. Pathology of obesity. (Jun 1999)
9. Pathology of radiation injury. (Aug 1998)
10. Rickets. (Aug 1998)
11. Non-neoplastic hazards of smoking. (Feb 1998)
12. Discuss the role of calcium in health and disease. (Aug 1984)
13. Childhood tumours. (May 2006)
14. Metabolic bone disease. (1996)
15. Obesity and other systemic diseases. (1996)
16. Give an account of the pathological consequences of radiation exposure. (Apr 1990)
17. Mechanism of action of radiation injury. (Oct 1992)
18. Dystrophin. (Nov 2007)
Chapter 10
1. Discuss the pathogenesis and laboratory diagnosis of Hemolytic disease of newborn. (Aug
1995)
2. Non accidental injury in children. (Sep 2003)
[7]

3. Give a short classification of inborn errors of metabolism. Discuss the pathology in glycogen
storage diseases. (Aug 1984)
4. Childhood renal tumours. (DNB 1995)
5. Tissue changes in plague. (DNB 1995)
6. Pathogenesis of cerebral malaria. (DNB 1996)
7. Lab diagnosis of childhood round cell tumours. (DNB 1997)
8. Fetal hydrops. (Nov 2006)
9. Phenylketonuria (Sep 2001)
10. Discuss the pathology of necrotizing enteritis. (Mar 1985)
Chapter 11
1. Discuss the risk factors for atherosclerosis and its recent concepts in pathogenesis of
atherosclerosis. (Jun 2008, April 1990, Mar 1985)
2. What are the recent trends in the etiology of atherosclerosis? (April 1987)
3. Anuerysms. (Nov 2007)
4. Discuss vasculitides. (Sep 2004)
5. Pathognesis of non infectious vasculitis. (Mar 2004)
6. Pathogenesis of atherosclerosis. (Feb 1997)
7. Hypersensitivity angitis. (Mar 1996)
8. Discuss the pathology of atherosclerotic diseases. (Mar 1992)
9. Describe the mechanisms of vasculitis and the syndromes associated with it. (1986)
10. Discuss the current concepts in atherogenesis. (May 2000)
11. Polyarteritis nodosa. (Sep 2001)
12. Aortic changes in atherosclerosis. (Aug 1998)
13. Aschoff nodule. (Sep 1997)
14. Role of growth factors in atherosclerosis. (DNB 1997)
Chapter 12
1. Discuss the pathology of cardiomyopathies. (Apr 2009)
2. Describe the current concepts in the etiopathgenesis and pathology of rheumatic heart
disease. (Nov 2008)
3. Discuss the etiopathogenesis , morphology and complications of myocardial infarction. Add a
note on lab diagnosis. (DCP Apr 2009)
4. Aschoff nodule. (Sep 1997)
5. Myocardial biopsy. (DCP May 1988)
6. Discuss the pathogenesis of lamellar subendocardial infarction of the heart. (Mar 1986)
7. Enzymes in heart disease. (Mar 1985)
8. Infectious endocarditis. (Nov 2006, May 2001)
9. Classify myocardial infarcts. Enumerate the enzyme changes in myocardial infarction. (May
2006)

[8]

10. Discuss the current concepts in the pathogenesis of ischemic heart disease. (Sep 2004, Sep
2001)
11. Discuss in detail the clinicopathological and functional forms of primaty cardiomyopathy. (Sep
2002)
12. Discuss briefly the pathology of cardiac conduction system. (Mar 2002)
13. Non infective endocarditis. (Dec 2000)
14. Discuss the pathogenesis and pathology of cardiomyopathies. (May 2000)
15. Complications of artificial valve. (Mar 1996)
16. Give an account of cardiomyopathies with special reference to aetiological concepts. (Apr
1990)
17. Discuss etiology, pathology and pathogenesis of cardiomyopathies.(Sep 2001, Feb 1985)
18. Cardiac pacemakers. (Mar 2004)
19. Left ventricular hypertrophy. (Aug 1998)
20. Lab diagnosis of ischemic heart disease. (Mar 1984)
21. Dilated cardiomyopathy. (DNB 1997)
22. Pathology of prosthetic materials and devices. (DNB 1998)
23. Discuss the etiopathogenesis and cardiac manifestations of onfective endocarditis. Explain the
current criteria and laboratory approach to the diagnosis of infective endocarditis. (Apr 2005)
Chapter 13
1.
2.
3.
4.
5.
6.
7.
8.
9.
10.
11.
12.
13.
14.
15.
16.
17.
18.
19.

Describe the lab diagnosis of multiple myeloma. (DCP Nov 2008)

Plasma cell leukemia. (DCP Jun 2008)
Discuss the pathology of follicular lymphoma and discuss its immunophenotyping. (Nov 2008)
Discuss the classification and diagnosis of T cell lymphoma. (Jun 2008)
Discuss human stem cell biopsy and therapy. (Apr 2009)
Discuss hairy cell leukemia. (Apr 2009)
Discuss the chromosomal abnormalities in childhood acute leukemia. (Nov 2008)
Discuss in detail the various classifications of leukemias. Discuss pathophysiology of chronic
myeloid leukemia. (Jun 2008)
Burkitts lymphoma. (Aug 1995)
Discuss the classification of lymphnode enlargement and give macroscopic and microscopic
appearances of Hodgkins disease (Apr 1987)
Sinus histiocytosis. (Mar 1985)
Cutaneous lymphoproliferative disorders. (nov 2006)
Thymic epithelial tumours. (Nov 2005)
Immunity in Hodgkins disease. (Nov 2005)
Discuss hodgkins lymphoma. (Sept 2004)
REAL classification of Non hodgkins lumphomas(Sep 2003)
Hypersplenism. (Sep 2002)
Angio immunoblastic lymphadenopathy. (mar 2002)
Leukemoid reaction. (sept 2001)
[9]

20.
21.
22.
23.
24.
25.
26.
27.
28.
29.
30.
31.
32.
33.
34.
35.
36.
37.
38.
39.
40.
41.
42.
43.
44.
45.
46.
47.
48.
49.
50.
51.
52.
53.
54.
55.
56.
57.

Pseudolymphoma. (May 2001)

Lymphnode in AIDS. (may 2001)
Classification of acute leukemias. (Sep 2001)
Langerhans cell histiocytosis. (Jun 1999,May 2000)
Discuss the merits and demerits of various classifications of Non hodgkins lymphoma. (Feb
1997)
Discuss the morphological and immunological classification of lymphomas. (Aug 1995)
Discuss histological diagnosis of Hodgkins disease. (Mar 1995)
Erythroleukemia. (Mar 1985)
Hairy cell leukemia. (Mar 1985, Feb 1994)
Macroglobulinemia. (Feb 1994)
Classify and discuss histiocytie disorders. (Apr 1987)
Myelodysplatic syndromes. (Apr 1987)
Bone marrow in health and disease. (Nov 2007)
Define ,classify and describe the lab diagnosis of acute leukemias. (May 2007)
Describe Waldenstrom macroglobulinemia. (May 2007)
Discuss acquired neutropenia. (May 2006)
Chronic myeloproliferative disorders. (Mar 2006)
Morphology of blast cell in acute leukemia. (May 2006)
Myelofibrosis. (Aug 1998)
Define and classify lymphoma. Discuss briefly the advantages and disadvantages of each
classification. (Apr 2005)
Discuss bone marrow transplantation in detail. (Apr 2005, Mar 2003, May 2000, Aug 1997)
Describe classification , lab diagnosis and recent concepts about MDS. (Sep 2004)
Causes of lymph node enlargement. Approach to diagnosis of lymphadenopathy. (Sep 2004)
Prognostic factors in multiple myeloma. (Sep 2003)
Immunophenotyping of acute leukemias. (Sep 2003, Nov 2007, Sep 2003)
Preleukemias. (Mar 2002, Aug 1995)
Myelodysplastic syndromes. (Sep 2002, Feb 1997, Apr 1987, Sep 2001)
Acute myelofibrosis. (Mar 2002, Aug 1998, Aug 1995)
Describe the recent concepts about myelodysplastic syndrome. (May 2001)
Discuss the pathology, diagnosis and prognosis of multiple myeloma. (May 2001)
Extra medullary myeloid cell tumours. (Dec 2000, Feb 1998)
Describe the plasma cell dyscrasias and add a note on the diagnostic criteria for multiple
myeloma. (Dec 1999)
Polymorphonuclear leucocyte granules. (Jun 1999)
Classify leukemias and discuss the recent advances in laboratory tests in histological typing of
leukemias. (Aug 1998)
Bone marrow failure. (Feb 1998, Sep 1997)
Discuss the classification and laboratory diagnosis of thalassemias. (Sep 1997)
Elaborate briefly the present concept of classification of acute leukemia. (Aug 1995)
What is M protein? Discuss different methods of its detection. (Aug 1995)
[10]

58.
59.
60.
61.
62.
63.
64.
65.
66.
67.
68.
69.
70.
71.
72.
73.
74.
75.
76.

77.

Polymacrocyte. (Aug 1995)

Give an account of hairy cell leukemia. (Feb 1994)
Classify leukemias and discuss the newer concepts on their etiology. (Mar 1997)
Classify and discuss histiocyte disorders. (Apr 1987)
Discuss the role of immunity in hodgkins disease. (May 2007)
Describe the advances in bone marrow pathology. (May 2007)
New therapies for chronic lymphocytic leukemias. (Nov 2005)
NK and NK/T cell neoplasms. (Nov 2005)
Diffuse large B-cell lymphoma. (Sep 2003)
Immunotherapy of chronic lymphocytic leukemia. (Sep 2003)
Discuss the non neoplastic lesions of lymphnodes. (May 2001)
Unusual types of lymphomas. (Sep 2002)
Discuss the recent concepts in the classification and diagnosis of thymic epithelial cell
tumours. (Dec 2000)
Describe classification , etiology, pathology and diagnosis of T cell malignant lymphomas.
(May 2001)
Transplantations of hematopoietic tissues. (Dec 1999)
Discuss the clinicopathological correlation in the recent classification of lymphomas and
leukemias. (Sep 1996)
Discuss recent trends in extranodal lymphomas. (Aug 1994)
Discuss the interpretation of lymph node biopsy and utility of special stains on it. (Apr 1987)
Discuss the recent histochemical methods which help to solve the morphological diagnostic
problems of leukemias and their application in prognosis and treatment of cases of leukemias.
(Aug 1985)
Name the plasma cell dyscrasias and related disorders. Discuss their applied aspect is
causation of various pathologies. (Aug 1984)

Chapter 14
1. Classify hemolytic anemias. Discuss etiopathogenesis and recent concepts in pathology of
sickle cell anemia. (Apr 2009, Sep 1997, Feb 1997)
2. Discuss the role of red cell cytochemistry in hematological disorders. (Apr 2009)
3. Discuss the pathophysiology and lab investigations of Von willebrand disease. (Apr 2009)
4. Discuss anemia in chronic diseases. (Nov 2008)
5. Discuss in detail laboratory diagnosis of auto immune haemolytic anemia. (Nov 2008)
6. Discuss the laboratory investigations in functional platelet disorders. (Nov 2008)
7. Discuss molecular basis and diagnosis of thalassemia. (Jun 2008)
8. Discuss in detail laboratory diagnosis of congenital dyserythropoietic anemias. (Jun 2008)
9. Discuss in detail biochemical indicators of coagulation. (Jun 2008)
10. Discuss the lab diagnosis of iron deficiency anaemia. (DCP Apr 2009)
11. Sideroblast. (DCP Apr 2009)
12. Peripheral smear study. (DCP Nov 2008)
[11]

13.
14.
15.
16.
17.
18.
19.
20.
21.
22.
23.
24.
25.
26.
27.
28.
29.
30.
31.
32.
33.
34.
35.
36.
37.
38.
39.
40.
41.
42.
43.
44.
45.
46.
47.
48.
49.
50.
51.

Anti coagulants. (DCP Nov 2008)

Bombay blood group. (DCP Nov 2008)
Platelet function tests. (DCP Nov 2008, Aug 1998)
Discuss etiopathogenesis and laboratory diagnosis of Megaloblastic anemia. (Jun 2008, Sep
1997)
Discuss preparation , storage and uses of blood components. (Jun 2008)
Auto immune thrombocytopenia. (Jun 2008)
Idiopathic thrombocytopenic purpura. (May 1988)
Laboratory diagnosis of DIC. (Apr 1987)
Discuss the etiopathogenesis , pathology of ITP. How will you investigate? (Sep 2001)
Polycythemia vera. (Sep 2001)
Basic hematological features of hemolytic anemia. (Sep 2001)
Discuss the pathogenesis and laboratory diagnosis of DIC. (Sep 2001)
Enumerate and classify autoimmune hemolytic anemias. Discuss pathogenesis and laboratory
diagnosis. (Mar 1992)
Safe blood transfusion (2001)
Significance of reticulocyte count. (2001)
Alpha/beta gene interaction in thalassemia. (2001)
Problems in blood transfusion. (Nov 2007)
Thrombocytes- morphology and function. (Nov 2007)
Define DIC. Describe its aetiopathogenesis, pathology and laboratory diagnosis. (May 2007)
Describe congenital dyserythropoietic anemias. (May 2007)
Describe the advantages and disadvantages of blood substitutes. (May 2007)
Pure red cell aplasia. (May 2006)
Laboratory diagnosis of bleeding disorders. (May 2006)
Fibrin degradation products.(Nov 2006, Mar 2003, Dec 2000. Feb 1995)
Causes of bleeding disorders. (Nov 2006)
Red cell membrane defects and diseases. (Nov 2006, Mar 2002)
Discuss the pathology and diagnostic laboratory test in b-thalassemia. (Aug 1998)
Reticulocyte count (Aug 1998)
Hemophilias. (Aug 1998, Mar 1992)
Define and classify immune hemolytic anemias. (Nov 2005)
Laboratory diagnosis of purpura. (Nov 2005)
Hemopoietic progenitor cells. (Nov 2005)
Vitamin K antagonists. (Nov 2005)
Structure and function of platelets. (Apr 2005)
Discuss and classify hemolytic anemias. Discuss about hereditary hemolytic anemias. (Apr
2005)
Discuss various blood componentsand used in transfusion. (apr 2005)
Erythrocyte cytoskeleton. (Sep 2004)
Molecular biology and lab diagnosis of B thalassemia. (Sep 2004)
Disorders of coagulation in neonates.
[12]

52.
53.
54.
55.
56.
57.
58.
59.
60.
61.
62.
63.
64.
65.
66.
67.
68.
69.
70.
71.
72.
73.
74.
75.
76.
77.
78.
79.
80.
81.
82.
83.
84.
85.

Molecular imaging in hematology.

Lab diagnosis and molecular biology of sickle cell disease. (Mar 2004)
Micro environment in hemopoiesis. (Sep 2003)
Pathophysiology and laboratory diagnosis of G6PD deficiency. (Sep 2003)
Functional platelet disorders. (Sep 2003)
Protein C deficiency. (Sep 2003)
Classify hemolytic anemias. Describe the lad methods in the investigation of hemolytic
anemias. (Sep 2002)
Qualitative platelet disorders. (Sep 2002)
Hazards of blood transfusion. (Sep 2002)
Discuss briefly the classification and laboratory investigations of deficiency anemias. (Mar
2002)
Discuss the role of platelets in health and disease. (Mar 2002)
Porphrias. (Mar 2002, May 2001,Mar 1992)
Discuss the laboratory diagnosis of hemoglobinopathies. (May 2000)
Osmotic fragility. (May 2000)
What is leuco erythroblastic reaction? Discuss the various causes producing leuco
erythroblastic reaction. (Dec 2000)
G6PD deficiency. (Dec 2000)
Discuss in detail erythropoiesis and its disorders. (Dec 1999)
Classify porphyrias. Discuss its genetic, metabolic and diagnostic aspects. (Jun 1999)
Describe the process of normal haemostasis. Write briefly about anticoagulant proteins. (Jun
1999)
Platelet antigens. (Jun 1999)
What are the alternatives of whole blood transfusion. Discuss the preparation and processing
of various fractions of blood for blood transfusion. (Jun 1999)
Sideroblastic anemia. (Jun 1999)
Classify thalassemias. How will you investigate a case of thalassemia. (Feb 1998, Sep 1997)
Discuss the diagnosis , management and prevention of mismatched blood transfusion. (Feb
1998)
7 yr male child came with a hematoma and swelling left knee following a trivial injury. How
will you investigate the case to come to a diagnosis. (Sep 1997)
Anticoagulants. (Sep 1997)
Packed cell volume. (Sep 1997)
Hemoglobinometry and its applications. (Sep 1997)
Blood transfusion reactions. (Feb 1997)
Von willebrands disease. (Feb 1997)
Christmas disease. (Aug 1995)
Non thrombocytopenic purpura. (Aug 1995)
Enumerate and classify causes of pancytopenia. Discuss pathogenesis and laboratory
diagnosis. (Feb 1995)
Dsicuss thalessemia. (Aug 1994)
[13]

86.
87.
88.
89.
90.
91.
92.
93.
94.
95.
96.
97.

Artificial blood. (Aug 1994)

Discuss lab investigations in a case of hemorrhagic disorder. (Oct 1992)
Autoblood transfusion. (Oct 1992)
Describe the role of fetal hemoglobin in health and disease. (May 2007)
Fetal hemoglobin synthesis and its stimulation. (Nov 2005)
Blood substitutes. (Nov 2005)
Stimulation of fetal hemoglobin synthesis using pharmacological agents. (Nov 2005)
Clinical uses of hemopoietic growth factors. (Sep 2003)
Antibody screening in blood transfusion therapy. (Sep 2003)
Protein C and is relevance. (Apr 1996)
Discuss the role of thrombophilic factors in inherited thrombotic disorders. (2001)
Significance of International noramlised ratio. (2001)

Chapter 15
1.
2.
3.
4.
5.
6.
7.
8.
9.
10.
11.
12.
13.
14.
15.
16.
17.
18.
19.
20.
21.
22.
23.
24.

Aetiopathogenesis and types of bronchogenic carcinoma. (DCP Nov 2008)

Classify pneumonias and describe the pathology of lobar pneumonia. (DCP Nov 2008)
Asbestos related diseases. (DCP May 2006)
Classify pneumoconiosis and discuss about asbestosis. (DCP Mar 2004, Sep 2001)
Describe the etiopathogenesis of bronchogenic carcinoma and discuss the histological types of
carcinoma lung. (DCP Sep 2003)
Reinfection tuberculosis. (DCP May 2000)
Describe the pathology and complications of bronchopneumonia. (DCP June 1999)
Bronchiectasis. (DCP Jan 1999)
Classify pneumoconiosis and discuss in detail about one of them. (DCP Sep 1996)
Discuss the role of bronchial lavage in pulmonary diseases. (June 2008)
Discuss the tumours of mediastinum. (Nov 2008, Aug 1985)
Complicated coal workers pneumoconiosis. (Mar 1996)
Classify pneumonias. What is the gross and microscopic picture of lobar pneumonia. (Aug
1995)
Discuss the pathology of emphysema. (May 1988)
Discuss the pathogenesis and pathology of pulmonary emphysemas. (Nov 1987)
Discuss the pathology noninfection and non neoplastic chronic lesions of the lung. (Apr 1987)
Intralobar sequestration of lung. (Mar 1985)
Pulmonary function tests. (Mar 1985)
Interstitial pneumonias. (May 2006, Sep 2001)
Discuss the current concepts in the etiopathogenesis of lung cancer. (Sep 2004)
Pathogenesis of immunological lung disease. (Mar 2004)
Idiopathic pulmonary fibrosis. (Sep 2003)
Discuss in detail the neoplastic and non neoplastic neuroendocrine proliferations of lung. (Sep
2002)
Pathology of pulmonary hypertension. (Mar 2002)
[14]

25. Discuss the dust associated respiratory diseases with general emphasis on asbestos associated
diseases. (Dec 1999)
26. Occupational lump disease. (Aug 1998)
27. Discuss adult respiratory distress syndrome. (Mar 1996)
28. Alpha 1 antitrypsin deficiency diseases. (Oct 1988)
29. Discuss the pathogenesis and pathology of COPD. (1986)
30. Granulomatous lesions of lung. (Sep 2001)
31. New WHO classification of lung tumours. (Nov 2007)
32. Atypical adenomatous hyperplasia of lung. (Mar 2004)
33. Discuss interstitial lung diseases. (Sep 2004, Aug 1998)
34. Prognostic indicators in small peripheral lung adenocarcinoma. (Sep 2003)
35. Pulmonary aspergillosis. (May 2001)
36. Hyaline membrane disease. (Sep 1996)
37. Sudden infant death syndrome. (DNB 1996)
38. Pulmonary endocrine system. (DNB 1998)
39. Cytological diagnosis of bronchogenic carcinoma. (DNB Feb 1992)
Chapter 16
1. Classify salivary gland tumours and discuss briefly pathology of malignant tumours of salivary
gland. (Nov 2008)
2. Discuss the role of FNAC in salivary gland lesions. (June 2008)
3. Discuss the pathology, precancerous lesions and carcinoma of the orla cavity. (Apr 1987)
4. Nasopharyngeal carcinoma.
5. Give an account of oropharyngeal leucoplakia and other precancerous lesions. Explain how a
pathologist can guide a clinician in management of such case. (Mar 1985)
6. Submucous fibrosis. (Mar 1985)
7. Basal cell adenoma of salivary gland. (2001)
8. Cytology of salivary gland tumours. (Nov 2007, DNB 1997)
9. Ameloblastoma. (May 1988)
10. FNAC of parotid tumours. (Aug 1994)
Chapter 17
1. Discuss the pathology and pathogenesis of lesions caused by Helicobacter pylori infection.
(Apr 2009)
2. Discuss etiopathogenesis and pathology of gastrointestinal lymphoma. (Nov 2008)
3. Describe the etiopathogenesis, morphology and complications of chronic gastric ulcer. (May
2006)
4. Baretts oesophagus. (Nov 2005, Feb 1998, Sep 2001)
5. Discuss the pathogenesis of ascites. Briefly discuss the laboratory tests done in its diagnosis.
(May 2001)
6. Discuss the etiopathogenesis, pathology and complications of enteric fever. (Sep 1997)
[15]

7. Discuss the etiopathogenesis of colon carcinoma. Describe the gross and microscopic features
of cancer in sigmoid colon. (Aug 1995)
8. Discuss the pathogenesis and pathology of various ulcerative lesions of large intestine. (Apr
1987)
9. Carcinoid syndrome. (DCP Apr 1987)
10. Discuss the pathology of polyps of the GI tract and with reference to malignancy. (Apr 1987)
11. Intestinal polyps. (Nov 2007)
12. Inflammatory bowel diseases. (Nov 2006, Sep 2004)
13. Discuss the pathology of obstructive lesions in small intestines. (May 2006)
14. Role of endoscopic biopsies in malabsorption syndromes. (May 2006)
15. Discuss the etiopathogenesis and pathology of gastric carcinoma. (Sep 2004)
16. Interpretation of small intestinal biopsies in malabsorption syndromes. (Mar 2004)
17. Molecular genetics of colonic cancer. (Sep 2003)
18. Gross and histologic classification of gastric carcinoma. (Sep 2002)
19. Angiodysplasia of colon. (May 2000, Feb 1998)
20. Hirschsprung disease. (Dec 1999, Mar 1992)
21. Define and classify gastritis. Describe the pathology of H.pylori gastritis. (Jun 1999)
22. Ulcerative colitis. (Aug 1998)
23. Gastrointestinal polyposis syndromes. (Feb 1997)
24. Discuss current concepts on peptic ulcer. (Aug 1995)
25. Make an account of ulcerative diseases of the colon and the role of the pathologist in helping
towards making a diagnosis. (Apr 1990)
26. Gastric analysis. (Mar 1985)
27. Classify and diffuse briefly in IBD. (Nov 1987)
28. Primary gastric lymphomas. (May 2000)
29. Describe the pathology of different ulcerative lesions of the bowel. (Apr 1987)
30. Myopathies of gastro intestinal tract. (Sep 2003)
31. Diagnosis of hirschsprung disease. (Sep 2003)
32. Mucosal biopsy in malabsorption syndromes. (Dec 2000)
33. Early gastric carcinoma. (May 2001)
34. Primary neuroectodermal tumours. (Feb 1998)
35. GIST. (June 1999)
36. Discuss interpretation of intestinal mucosal biopsy. (Apr 1996)
37. Hisotchemistry of hirschsprung disease. (Feb 1995)
Chapter 18
1.
2.
3.
4.
5.

Biliary cirrhosis. (May 2007)

Describe the classification and etiopathogenesis of cirrhosis. (Nov 2005)
Describe the etiopathogenesis and pathology of chronic cholecystits. (Sep 2003)
Classify cirrhosis of liver and describe the etiopathogenesis of alcoholic cirrhosis. (Mar 2003)
Nutmeg liver. (Jun 1999)
[16]

6.
7.
8.
9.
10.
11.
12.
13.
14.
15.
16.
17.
18.
19.
20.
21.
22.
23.
24.
25.
26.
27.
28.
29.
30.
31.
32.
33.
34.
35.
36.
37.
38.
39.
40.
41.
42.
43.

Gall stones. (DCP Jun 1999, Oct 1992)

Define cirrhosis. Describe the etiopathogenesis of micronodular cirrhosis. (Jun 1999)
Discuss the pathology and laboratory findings in Hepatitis B infection. (Aug 1998)
Describe the pathology of chronic active hepatitis. (DCP Sep 1997, Feb 1985)
Assessment of liver function by lab investigations. (Apr 2009)
Serum bilirubin. (Apr 2009)
Define jaundice. Discuss laboratory diagnosis of jaundice.
Discuss application of various biochemical tests to differentiate the type of jaundice. (Nov
2006)
Describe in detail liver function tests. (Sep 2004)
Discuss the pathology and pathogenesis of primary biliary cirrhosis. (Jun 2008)
Discuss the pathology of noncirrhotic portal fibrosis. (Nov 2008)
Female 35 years presents with history of passing high coloured urine and pruritus. How will
you investigate her to know the diagnosis. (DCP Aug 1995)
Noncirrhotic portal hypertension. (Mar 1985)
Classify hepatitis. Discuss the role of serodiagnosis and follow up of viral hepatitis. (May 2006)
Histological classification of tumours of gall bladder and extrahepatic bileducts. (Nov 2005)
Drug induced and toxic liver cell injury. (Mar 2004)
Neonatal colestasis. (Sep 2003)
Discuss the spectrum of alcoholic liver disease. ( Mar 2002)
Hepatitis C infection. (Aug 1998, Feb 1998, Sep 2001)
Discuss the spectrum of viral hepatitis and their laboratory diagnosis. (Aug 1998)
Non A non B hepatitis. (Feb 1997)
Pathology of Indian childhood cirrhosis. (Mar 1992, Aug 1985)
Immunocytochemistry of liver tumours. (Mar 1992)
Discuss the classification and etiopathogenesis of cirrhosis liver. (Apr 1990)
Intrahepatic cholestasis. (Mar 1985)
Give a brief summary of bilirubin metabolism. Tabulate and discuss disorders of bilirubin
metabolism. (Apr 1987)
Discuss the laboratory diagnosis of jaundice. (May 2007)
Serum and urine examination in jaundice. (May 2007)
Discuss the pathology and pathogenesis of alcoholic liver disease. (May 2000)
Infantile jaundice. (Sep 2001)
Modified H.A.I (histological activity index) scoring of chronic hepatitis. (Mar 2004)
Classify gall stones with their characteristics. Discuss the current concepts in the formation of
gall stones. (Sep 2004)
Discuss the recent concepts about alcoholic liver disease. (Feb 1998)
Cholelithiasis. (Aug 1998)
Disorders leading to cirrhosis in pediatric age group. (Aug 1997)
Primary sclerosing cholangitis. (Feb 1997)
Alcohol related liver injury. (Apr 1996)
Give an update of liver tumours. (Aug 1994)
[17]

44. Discuss the recent concepts of viral hepatitis with special reference to the role of Hepatitis B
infection. (Apr 1987)
45. Classification of hemochromatosis. (Nov 2005)
Chapter 19
1. Describe the pathology of chronic pancreatitis. (Jan 1999, May 2001)
2. Amyloid pancreatitis. (Jan 1999)
3. Discuss the etiopathogenesis, pathology and lab diagnosis of acute pancreatitis. (Jun 2008)
Chapter 20
1.
2.
3.
4.
5.
6.
7.
8.
9.
10.
11.
12.
13.
14.
15.
16.
17.
18.
19.
20.
21.
22.
23.
24.
25.
26.
27.
28.

Wilms tumour. (Jun 2008)

Polycystic kidney. (May 2007)
Nephrogenic oedema. (Feb 1997)
Describe the gross and microscopic features of renal cell carcinoma. (Aug 1995)
Renal oedema. (Aug 1995)
Discuss the pathophysiology of chronic renal disease. (Apr 1987)
Discuss the feasibility and utility of special techniques in studying renal biopsy. (Apr 1987)
Discuss the immunological investigations of renal disease. (Aug 1984)
Renal cysts. (Nov 2007)
Oncocytomas. (Nov 2007)
Discuss the classification, characteristics and pathology of renal cell carcinoma. (Sep 2004)
Childhood renal neoplasms. (Mar 2004)
Discuss cystic disease of kidney. (Sep 2004)
Pathogenesis and immunological profiles of primary glomerular disease. (Sep 2003)
Discuss the renal changes in systemic diseases. (May 2001)
Discuss the pathology and laboratory diagnosis of plasma cell dyscrasias. (Sep 2001)
Drug toxicity in the kidney. (May 2000)
Ig A nephropathy. (Dec 1999)
Congenital cystic lesions of kidney. (Feb 1997)
Nephroblastoma. (Mar 1995, Mar 1985)
Discuss rapidly progressive glomerulonephritis. (Oct 1992)
Discuss the recent concepts of aetiopathogenesis of glomerulonephritis and usefulness of
renal biopsy in this condition. (Apr 1990)
Discuss the pathology of primary glomerulopathies. (Oct 1988)
Define renal dysplasia. Explain the diagnostic criteria and pathological significance of the
lesion. (1986)
Discuss the feasibility and utility of special techniques in study of renal biopsy. (1986)
Discuss the renal changes in systemic disorders. (Aug 1985)
Discuss the clinicopathological correlations of the manifestations of acute nephritis. (Mar
1985)
Extrarenal uremia. (Mar 1985)
[18]

29.
30.
31.
32.
33.
34.
35.
36.
37.
38.
39.
40.
41.
42.
43.
44.
45.
46.
47.
48.
49.
50.
51.

52.
53.
54.
55.

Clear cell sarcoma of the kidney. (May 2000)

Renal biopsy and interpretation in various diseases. (prefinal)
Microalbuminuria. (Mar 2004, May 2000, Feb 1998)
Interstitial nephritis. (Sep 2001)
Urinary sediments. (Dec 2000, DCP Apr 2005)
Bence jones proteinuria. (Sep 1997)
Give an account of renal function tests. (Feb 1994, Apr 1996)
Dilution and concentration test for renal function . (Oct 1992)
Discuss the pathophysiology of chronic renal disease. (Apr 1987)
Role of cytology in the diagnosis of renal transplant rejection. (Sep 2003)
Discuss the pathophysiology of acute renal failure following obstetrical shock and the role of
laboratory in management of the same. (Feb 1985)
Give a short histological classification of glomerular diseases. Discuss their aetiopathogenesis.
(Aug 1984)
Malakoplakia. (Nov 2006)
Cystic disease of the kidney. (DNB 1996)
Immune mediators in glomerular injury. (DNB 1995)
Blastemal lesions of kidney. (DNB 1997)
Cytological diagnosis of kidney transplant rejection. (DNB 1998)
Lab diagnosis of nephritic syndrome. (DNB 1998)
Discuss the etiopathogenesis and morphology of chronic pyelonephritis. (DCP Mar 2003,Mar
2004)
Flea bitten kidney. (DCP Mar 2004)
Enumerate glomerular diseases and write in detail the pathology, pathogenesis of acute
diffuse proliferative glomerulonephritis. (DCP Sep 2002)
Classify glomerular diseases. Discuss about the etiopathogenesis and laboratory diagnosis of
nephrotic syndrome. (DCP May 2000)
25 yrs female came with history of puffiness of face and pedal oedema. Discuss the
differential diagnosis . how will you investigate the case to arrive at a diagnosis. (DCP June
1999)
Discuss the possible investigations for proteinuria in adults. (DCP Aug 1998)
35 yr old adult male presented with massive oedema, puffiness of face, proteinuria of short
duration. How will you investigate such a case? Discuss the various tests. (DCP Sep 1996)
Ketonuria. (DCP Apr 2009)
Discuss the urinary findings in various renal and urinary tract infections. (DCP Nov 2008)

Chapter 21
1.
2.
3.
4.

Seminoma. (DCP Apr 2005, Aug 1998)

Urolithiasis. (DCP Mar 2003, Aug 1998)
Classify tumours of testis and describe the pathology of seminoma. (DCP Jan1999)
How will you investigate a case of male infertility. (DCP Sep 2003)
[19]

5.
6.
7.
8.
9.
10.
11.
12.
13.
14.
15.
16.
17.

Discuss the premalignant lesions of prostate. (Nov 2008)

Describe prostatic intraepithelial neoplasia. (May 2007, 2001)
Application of gleason score in grading carcinoma prostate. (May 2006)
Testicular biopsy. (Apr 2005, Mar 1985)
Male infertility. (Mar 2004)
Diagnostic and prognostic markers of prostatic cancer. (Sep 2003)
Discuss the etiology , pathology and recent developments in diagnosis of urinary bladder
carcinoma. (Jun 1999)
Discuss the role of FNAC testis in infertility. (Apr 2009,Sep 2001)
Discuss the importance of semen analysis in infertility. (Jun 2008)
Enumerate the causes of male infertility . add a note on laboratory diagnosis of male
infertility. (Dec 1999, Nov 2005)
Discuss the etiopathogenesis and pathology of prostatic carcinoma. Write briefly on the
recent advances in the knowledge of premalignant lesions of the prostate. (Sep 2001)
Leydig cell agenesis. (Mar 2004)
Discuss the etiopathogenesis of cancer of prostate. Write briefly on recent advances in
diagnosis of prostatic carcinoma. (Dec 1999)

Chapter 22
1.
2.
3.
4.
5.
6.
7.
8.
9.
10.
11.
12.
13.

14.
15.
16.

Krukenberg tumour. (DCP Apr 2009, Apr 2005)

Carcinoma cervix. (DCP Apr 2009)
Teratoma. (DCP Nov 2008)
Mucoepidermoid carcinoma. (DCP Nov 2008)
Discuss pathology of ovarian tumour. (DCP May 2007)
Carcinoembryonic antigen. DCP May 2006, Mar 2004)
Classify tumours of ovary and describe pathology of mucinous cystadenoma of ovary. (DCP
Sep 2003)
How will you investigate a case of bleeding per vaginum in post menopausal woman. (DCP
Mar 2003)
Gonadoblastoma. (DCP Mar 2003)
Cervical intraepithelial neoplasia. (DCP Sep 2002, Mar 1985)
Trophoblastic tumours. (DCP May 2000)
Classify ovarian tumours and describe the pathology of krukenburg tumour. (DCP Jun 1999)
35 yr female came with history of bleeding per vaginum of 3 days following 3 months
amenorrhoea. Following admission she had a severe bout of hemoptysis and collapsed .
discuss the differential diagnosis. How will you investigate the case to arrive at a diagnosis.
(DCP Sep 1997)
Carcinoma cervix. (DCP Jun 1999)
Post menopausal lady presents with bleeding per vaginum . how will you investigate her?
Describe the microscopic feature probable diagnosis. (DCP Sep 1996)
Discuss the current concepts in pathogenesis of endometrial carcinoma. (Nov 2008)
[20]

17. Discuss the recent concepts in pathology and pathogenesis of metaplasia in female genital
tract. (Apr 2009, May 2007)
18. Enumerate the microscopic variants of endocervical adenocarcinoma and discuss its
etiopathogenesis and pathology. (Jun 2008)
19. Immature teratoma. (Nov 2007)
20. Describe stromal tumours of ovary. (May 2007)
21. Yolk sac tumours. (Nov 2006)
22. Aetiology of carcinoma cervix. (Nov 2006, Aug 1998)
23. Discuss the pathology of sex cord stromal tumours of ovary. (May 2006)
24. Classify ovarian tumours. Describe in detail hormone producing ovarian tumours. (Apr 2005)
25. Discuss the value of endometrial biopsy in the diagnosis of dysfunctional uterine bleeding.
(Sep 2004)
26. Discuss the current concepts in the pathogenesis of cervical cancer. (Sep 2004)
27. Classify ovarian tumours. Add a note on their histogenesis and immunohistochemical
diagnosis. (mar 2004)
28. Enumerate and discuss the infectious diseases of female genital tract. (Sep 2003)
29. Discuss the pathology of female infertility. (May 2000)
30. Sex cord stromal tumours of the ovary. (Sep 1996)
31. Classify ovarian tumours and discuss th pathology and pathogenesis of thecoma. (Apr 1987)
32. Discuss the pathology of germ cell tumours. (Apr 1987)
33. FIGO staging of ovarian cancer. (Nov 2005)
34. Describe the pathological features of carcinoma cervix. (Mar 2003)
35. Dating of endometrium. (Dec 2000)
36. K cells in endometrium. (Mar 1996)
37. Arias stella reaction. (Aug 1995)
38. Describe the pathology of malignant trophoblastic tumours. (Mar 1995)
39. Endometrial changes in patients taking oral contraceptive pills. (Oct 1992)
40. Write a comprehensive essay of the role of endometrial biopsy on female infertility. (Apr
1990)
41. Age related changes in gynaec cytology. (May 2006)
42. Endometrial hyperplasia. (Sep 2001)
43. Application of image analysis in CIN. (Nov 2007)
44. New advances in endometrial carcinoma. (Nov 2007)
45. Prognostic factors in endometrial carcinoma. (Nov 2005)
46. Advances in endometrial pathology. (mar 2004)
47. Drug induced changes in female genital tract. (Sep 2003)
Chapter 23
1. Phyllodes tumour. (DCP Apr 2009, Mar 2003)
2. Diagnostic and prognostic features of carcinoma of breast. (DCP Apr2009)
3. Discuss the role of FNAC in benign and malignant tumours of breast. (CP Nov 2006, Sep 2004)
[21]

4.
5.
6.
7.
8.
9.
10.
11.
12.
13.
14.
15.
16.
17.

Discuss the differential diagnosis of lump in breast in female aged 30 years. (May 2006)
Histological grading of breast carcinoma. (Mar 2004)
Ductal carcinoma in situ. (Mar 2003)
Describe the FNAC of malignant breast neoplasms. (May 2007)
Discuss in detail premalignant lesions of breast. (Apr 2009, Jun 2008)
Discuss the diagnostic procedures to be adopted in a case of lump breast with nipple
discharge. (Apr 1987,1986)
Fibrocystic disease of breast. (Mar 2003)
Discuss cytology of breast lesions. (Oct 1992)
Breast implants. (Sep 2003)
Oestrogen receptors and breast cancer. (Aug 1994)
Prognostic indices in breast carcinoma. (DNB 1995)
Precancerous lesions of breast. (DNB 1998)
BRCA-1 and its role in breast carcinoma.
Risk assessment in breast. (Nov 2006)

Chapter 24
1. Discuss the pathology of anterior lobe of pituitary. (Apr 2009)
2. Discuss the thyroid function tests and their alteration in pathologic states. (Nov 2008, Nov
1987)
3. Discuss the pathogenesis of diabetes mellitus. (Apr 2009)
4. Discuss the criteria for diagnosis of follicular thyroid neoplasms and related conditions. (Nov
2008)
5. Describe the etiopathogenesis and recent concepts in papillary carcinoma of thyroid. (Jun
2008)
6. Hashimotos thyroiditis. (DCP Nov 2008, Sep 2004)
7. Discuss tumours of thyroid. (DCP Jun 2008, Oct 1992)
8. Multiple endocrine neoplasia. (DCP Nov 2006)
9. Discuss the role of FNAC in various thyroid lesions. (DCP Nov 2005, Apr 2005)
10. Describe the renal changes in diabetes mellitus. (DCP Sep 2004)
11. Pheochromocytoma. (DCP Sep 2004, Aug 1998)
12. Classify the tumours of thyroid and describe the pathology of medullary carcinoma of thyroid.
(Mar 2004)
13. Discuss in detail immunology of diabetes mellitus. (Jun 1999)
14. Kimmel Stiel Wilson syndrome. (Sep 1997)
15. Thyroid in thyrotoxicosis. (Apr 1987)
16. Estrogen as promoter of neoplasia. (Apr 1987)
17. Discuss the histological and histochemical patterns in hormone secreting tumours. (Mar 1986)
18. Autoimmune thyroiditis. (Nov 2007)
19. deQuervains thyroiditis. (May 2006)
20. Immunohistochemistry of pheochromocytoma. (Nov 2005)
[22]

21.
22.
23.
24.
25.
26.
27.
28.
29.
30.
31.
32.
33.
34.
35.
36.
37.
38.
39.
40.

Tumours of adrenal medulla. (Mar 2004)

Role of non enzymatic glycosylation in the pathogenesis of diabetes complications. (Sep 2002)
Limitations of FNAC of thyroid lesions. (Sep 2001)
Hypercalcemia in malignancy. (Dec 2000)
Discuss diabetic microangiopathy. (1986)
Multiple endocrine adenomas. (Mar 1985)
Biochemical abnormalities in blood in a case of hypertension due to primary aldosteronism.
(Feb 1994)
Glycosylated hemoglobin. (Nov 2006)
FNAC of thyroid lesions. (Nov 2006)
Thyroid function tests. (prefinal)
Describe the principles of fine needle aspiration cytology. Discuss its usefulness in the
diagnosis of thyroid lesions. (Sep 2002)
Hyperglycemia sine glycosuria. (Aug 1985)
Discuss thyroid functions in health and disease. (Feb 1995)
Criteria for malignancy in endocrine tumours. (Nov 2007)
Discuss the current classification, revised diagnostic criteria and pathogenesis of diabetes
mellitus. (Sep 2004)
Recently diagnosed variants of papillary carcinoma thyroid. (Sep 2002)
C cell lesions. (Dec 1999)
Discuss the current concepts in diabetes mellitus. (Feb 1995)
discuss the etiopathology and pathogenesis of thyroiditis. (Feb 1985)
Cytodiagnosis of lesions of thyroid gland. (2001)

Chapter 25
1.
2.
3.
4.
5.
6.
7.
8.
9.
10.
11.
12.
13.
14.
15.

Discuss the progress in diagnosis and prognosis of malignant melanoma. (Apr 2009)
Discuss the value of immunoflourescence in skin disorders. (Jun 2008)
Discuss the common malignant lesions of skin. (DCP Nov 2008)
Causes and mechanism of hyperpigmentation due to melanin. (Nov 2005)
Basal cell carcinoma (Apr 1987)
Discuss pigmented cutaneous lesions. (Aug 1985)
Keratinocytic lesions of skin. (Nov 2005)
Immunofluorescence of vesico-bullous lesions of skin. (Nov 2007, Mar 2004, Sep 2002)
Describe the pathology of bullous disorders of skin. (Dec 2000)
Staging of melanoma. (Aug 19950
Bullous lesions of skin. (Mar 1995)
Synovial biopsy. (Mar 1995)
Vitiligo. (Oct 1992)
Melanotic lesions of skin. (Mar 1992)
Discuss the classification, staging and diagnostic problems of malignant melanoma. (Mar
1985)
[23]

16. Discuss the application of enzyme histochemistry and monoclonal antibodies on lympho
proliferative conditions of the skin. (Mar 1986)
17. New approaches to the biology of melanoma. (Mar 2004)
18. Discuss the various skin manifestations due to internal disease. (Sep 2004)
19. Cutaneous lymphoproliferative disorders. (Sep 2001)
20. Skin adnexal tumours. (2001)
21. Discuss the pathology in pigmentary disorders affecting skin. (Aug 1984)
22. Describe the morphological features of different fungal infections of the skin. (2001)
Chapter 26
1.
2.
3.
4.
5.
6.
7.
8.
9.
10.
11.
12.
13.
14.
15.
16.
17.
18.
19.
20.
21.
22.
23.
24.
25.
26.
27.
28.

Discuss the recent concepts in the pathology of chondrosarcoma. (Nov 2008)

Discuss the value and limitations of FNAC in evaluating soft tissue tumours. (Nov 2008)
Discuss the pathology of non neoplastic lesions of synovial membrane joints. (Apr 2009)
Discuss the significance of antineutrophil cytoplasmic antibody. (ANCA). (Nov 2008)
Discuss myofibroblastic proliferation mimicking soft tissue sarcomas. (Nov 2008)
Ewings sarcoma. (DCP May 2007,Nov 2005)
Osteosarcoma. (DCP May 2006)
Write in detail about usefulness of immunehistochemistry in soft tissue tumours. (DCP Apr
2005)
Classify the tumours of the bone and describe the pathology of osteosarcoma. (DCP Mar 2003,
May 2000)
Classify bone tumours and describe the pathology of Ewings sarcoma. (Sep 1997)
Discuss the role of synovial fluid analysis in clinical diagnosis. (DCP Jun 2008)
Urea cycle defects. (Dec 1999)
Gout (Sep 1997)
Giant cell lesions of the bone. (DCP May 1988, Nov 1987, Mar 2002, Apr 1987)
Inflammatory bone disease. (DCP May 1988)
Ameloblastoma (DCP May 1988)
Bone in osteogenic sarcoma. (Apr 1987)
Describe the pathology of different ulcerative lesions of the bone. (Apr 1987)
Discuss the differential diagnosis of giant cell lesions of bones. (Mar 1986, Sep 2001)
Variations of osteosarcoma. (Nov 2007)
Metabolic arthropathies. (Nov 2006)
Fibrous lesions of bone. (Nov 2005)
Discuss the importance of immunohistochemistry and other markers in the diagnosis of soft
tissue sarcomas. (Sep 2004)
Differential diagnosis of pathological fractures in elderly females. (Mar 2004)
Discuss pathology of lytic lesions of bone. (Mar 2003)
Chondrosarcoma variants. (Sep 2003)
Immunohistochemical markers in soft tissue tumours. (Sep 2003)
Discuss etiology, pathology and diagnosis of metabolic disorders of bone. (Dec 2000)
[24]

29.
30.
31.
32.
33.
34.
35.
36.
37.
38.
39.
40.

Osteopetrosis. (Feb 1998)

Chondromyxoid fibroma. (Mar 1996)
Factors influencing prognosis of chondrosarcoma. (Mar 1992)
Discuss bone disease in chronic renal failure. (1986)
Discuss the pathology of bone disorders in oldage. (Aug 1985)
Discuss the cystic lesions of the bone. (Mar 1985)
Extraosseous giant cell tumours. (Mar 1985)
R.A factor. (Aug 1994)
Synovial biopsy. (Sep 2001)
Discuss primary malignant bone tumours. (2001)
Osteomyelitis. (2001)
Classify soft tissue tumours . discuss the ultrastructural, immunohistochemical and genetic
aspects of soft tissue tumours. (Jun 1999)

Chapter 27
1.
2.
3.
4.
5.
6.
7.
8.
9.
10.
11.

Discuss the recent concepts in pathology of skeletal muscle tumours. (Apr 2009)
Myasthenia gravis. (Sep 2002)
Peripheral nerve biopsy. (Dec 1999)
Duchenne muscular dystrophy. (Jun 1999)
Muscle biopsy. (Mar 1995)
Mitochondrial inclusion myopathy. (2001)
Enzymes involved in muscle diseases. (Feb 1995)
Congenital myopathy. (Sep 2001)
Skeletal muscle tumours. (Mar 2001)
Write briefly on advances in muscular dystrophy and myopathies. (May 2001, Feb 1998)
Discuss the diagnostic application s of muscle biopsy. (Feb 1997)

Chapter 28
1.
2.
3.
4.
5.
6.
7.
8.
9.
10.
11.

Classify degenerative disease of brain and discuss about Alzheimers disease. (Apr 2009)
Discuss the pathology of Inflammatory neuropathies. (Jun 2008)
Discuss the pathology of paraganglioma. (Apr 2009)
Classify brain tumours. Discuss the pathology of meningioma. (Nov 2008)
Discuss human prion diseases. (Nov 2008)
Medulloblastoma. (DCP May 2000, Mar 2001)
Neuroblastoma. (DCP Jun 1999)
Astrocytoma. (DCP Jan 1999)
Meningioma. (DCP Sep 1997)
Describe the C.S.F analysis in meningitis. (Apr 2009)
Classify meningitis and discuss the laboratory tests useful in diagnosis of various types. (DCP
Aug 1998)
12. C.S.F in tuberculous meningitis. (DCP Sep 1996)
[25]

13.
14.
15.
16.
17.
18.
19.
20.
21.
22.
23.

Metachromatic leucodystrophy. (Nov 2005)

Glioblastoma. (Nov 2007)
Alzheimers disease. (Nov 2006, Dec 2000)
Mitochondrial encephalopathies. (Nov 2006)
Subacute sclerosing panencephalopathy. (May 2000)
Ependymoma. (Feb 1998)
Brain tumours in pediatric age group. (1996)
Slow viral diseases of brain. (Aug 1995)
Define and discuss the important pathological aspects of cerebro vascular disease. (Mar 1992)
Formation , circulation and alterations of CSF in meningitis. (Sep 2004)
Describe pathology and pathogenesis of Alzheimers disease. (Sep 2001)

Chapter 29
1. Discuss tumours of orbit. (Nov 2005)
2. Pseudotumours of orbit. (Sep 2003)
3. Retinoblastoma. (Oct 1992)
Miscellaneous
1.
2.
3.
4.
5.
6.
7.
8.
9.
10.
11.
12.
13.
14.
15.
16.
17.
18.
19.
20.
21.

Sphingolipidosis. (Mar 2003)

Histopathologist and internet. (Sep 2001)
Age related pathologic changes in various organs and systems. (Sep 2001)
Discuss the role of enzyme histochemistry in the understanding of tissue lesions. (May 2000,
Sep 1996, Sep 1995)
Discuss briefly the structure of basement membrane and its alterations in diseased stages.
(Sep 1997)
Pathological lesions encountered in drug addiction. (Sep 1994)
What is the role of frozen section as a rapid and in histopathology. (Nov 1987)
Discuss the experimental production of different tumours. (Nov 1987)
Explain Hybridoma technique. (Mar 1986)
Discuss chromosome breakage syndromes. (Aug 1984)
Exfoliative cytology. (Sep 2001)
Application of new techniques to cytopathology. (Sep 2001)
Discuss the diagnostic utility of electrophoretic fractionation of plasma proteins. (Mar 1992)
Blood lipiids. (Mar 1992)
Assessment of leucocyte function. (Mar 1992)
Counter electrophoresis. (Mar 1985)
Discuss the role of fluorescence microscope in laboratory diagnosis. (Feb 1994)
Behcets syndrome. (Feb 1994)
Myospherulosis. (Feb 1994)
Discuss the impact of information technology in diagnostic pathology. (2001)
Pitfalls in FNAC. (Nov 2007)
[26]

22.
23.
24.
25.
26.
27.
28.
29.
30.
31.
32.
33.
34.
35.
36.
37.
38.
39.
40.
41.
42.
43.
44.
45.
46.
47.
48.
49.
50.
51.
52.
53.
54.
55.
56.
57.
58.
59.

Isoenzymes. (Nov 2007)

LE cell test and interpretation. (Nov 2007)
Describe the utility of urine microscopy in diagnosis and prognosis. (May 2007)
Describe the role of serum lipids in health and disease. (May 2007)
Cytology in non neoplastic diseases. (May 2006)
Stains used in vaginal cytology. (Nov 2006)
Lazy leucocytic syndrome. (Nov 2006)
Scope of auto transfusions. (Nov 2005)
Computer aided cytomorphology. (Nov 2005)
Organ changes in Hypereosinophilic syndrome. (Nov 2005)
Disucc the metabolism of copper in man and the significance of estimation of ceruloplasmin.
(Apr 2005)
How do you organize a cytology lab for a 250 bedded hospital in a district. (Apr 2005)
Problems in pediatric blood transfusions. (Mar 2004)
Sports hematology. (Mar 2004)
Chorionic villus biopsy. (Mar 2004)
Antibody screening in blood transfusion therapy. (Sep 2003)
Discuss the role of automation in clinical pathology. (Dec 2000)
Urinary sediments. (Dec 2000)
Frozen section. (Aug 1998)
Vaginala cytology. (DCP Sep 1997)
Hormonal cytology. (Sep 1997)
Discuss the role of FNAC in surgical practice. (Feb 1997)
Quality control in laboratory. (Aug 1996)
Discuss the role of fine needle aspiration biopsy as aid in arriving at a diagnosis of different
lesions. (April 1987, Aug 1995)
Refinements in tumour staging. (Sep 2002)
Role of microwave technology in histopathology. (Sep 2002)
Molecular pathology of small round cell tumours. (May 2000)
Describe the role of DNA technology in histopathology. (Aug 1997)
Pathology of coronary arteries in sudden ischemic death. (Aug 1997)
Immunoblotting. (Sep 1996)
Histometry. (Aug 1995)
Decalcification techniques. (Aug 1995)
Uses of microwaves in pathology. (Aug 1995)
Immunoflourescence techniques. (Aug 1995)
Laboratory precautions in handling materials related to AIDS patients. (Feb 1995)
discuss the role electron microscopy in the diagnostis of tumours. (Feb 1995)
plan and discuss the relevant important investigations needed in an intensive cardiac care
unit. (Aug 1985)
Describe the cells of APUD( Amino Precursor Uptake Decarboxylation) series and discuss the
recent concepts regarding the neoplasm arising out of them. (Feb 1985)
[27]

60. Discuss the application of clinical cytology (exfoliative) in diagnosis of human diseases. (Feb
1985)
61. Plan and discuss the relevant lab investigations in cases developing iatrogenic hematological
problems. (Feb 1985)

[28]