Documente Academic
Documente Profesional
Documente Cultură
Faculty of Pharmacy
An Outcomes-Based Teaching-Learning Program for Chemistry of Biomolecules
2nd Semester, A.Y. 2014-2015
Course Title:
Chemistry of Biomolecules
Course Number:
BIOCHEM 1
Credit Units::
Contact Hours:
Course Placement:
Prerequisite:
CHEM 200
Course Facilitator:
Course Description:
The course deals with the structure and function, isolation, purification and characterization of biomolecules:
carbohydrates, proteins, lipids and nucleic acids, transmission and expression of genetic information, and
generation and storage of metabolic energy.
Prepared by:
Reviewed by:
Approved by:
Date of Approval:
05 January 2015
Content
Teaching-Learning
Activities
Assessment Tasks
1. Scope of Biochemistry
Interactivity or Interactive
Work
Lecture Forum
Analytic assessment
Scientific laboratory
session
Lab practical
CILO 2
Content
Teaching-Learning
Activities
Assessment Tasks
Interactive Lecturing
Problem Sets
Documented Problem
Solution
Scientific Laboratory
Session, Cookbook
Laboratory Work
Analytic Assessment
Lab Practical
Whats the Principle
Paper Prospective
Gapped Lecture
Summarizing
Lecture Forum
Analytic Assessment
1. 1, 2, 3 and 4 structures
2. Denaturation
Assigned Reading
Content
Teaching-Learning
Activities
Assessment Tasks
Gapped Lecture
Problem Sets
Documented Problem
Solution
Whats the Principle
Paper Prospective
Lab Practical
Gapped Lecture
Lecture Forum
Three-Minute Essay
Focused Listing
Content
Teaching-Learning
Activities
Nomenclature
Analytic Assessment
Paper Prospective
Lab Practical
Assessment Tasks
Gapped Lecture
Focused Listing
Lecture Forum
Three-Minute Essay
Analytic Assessment
Interactive Lecturing
Problem Sets
Documented Problem
Solution
Content
Teaching-Learning
Activities
Assessment Tasks
Ribonucleotides/Deoxyribonucleotides
2. Steps in replication
Scientific Laboratory
Session, Cookbook
Laboratory Work
Gapped Lecture
Summarizing
Lecture Forum
Analytic Assessment
Assigned Reading
Workshop
Gapped Lecture
Summarizing
Lecture Forum
Analytic Assessment
Content
Teaching-Learning
Activities
Assessment Tasks
rRNAand mRNA
Assigned Reading
3. Ribozymes
1. Genetic code
Gapped Lecture
Focused Listing
Lecture Forum
Three-Minute Essay
Analytic Assessment
Lecture Forum
Summarizing
1. Monosaccharides, oligosaccharides
and polysaccharides
Gapped Lecture
Lecture Forum
Assigned Reading
Summarizing
Analytic Assessment
Scientific Laboratory
Session, Cookbook
Laboratory Work
Paper Prospective
Whats the Principle
Lab Practical
Content
Teaching-Learning
Activities
Assessment Tasks
Gapped Lecture
Lecture Forum
Assigned Reading
Focused Listing
Summarizing
Scientific Laboratory
Session
Cookbook Laboratory Work
Content
Teaching-Learning
Activities
Assessment Tasks
Empty Outlines
Lecture Forum
Analytic Assessment
Assigned Reading
CILO 1
Gapped Lecture
2. Glycolytic pathway
* Substrate level phosphorylations
Oxidation Reduction reactions
Unit XV: Storage Mechanisms and
Control in Carbohydrate Metabolism
1. Glycogen metabolism
*Gluconeogenesis
Gapped Lecture
Empty Outlines
Lecture Forum
Analytic Assessment
CILO 1
Assigned Reading
Unit XVI: The Citric Acid Cycle
Analyze the reactions of the citric
acid cycle CILO 3
Lecture Forum
Summarizing
Gapped Lecture
Problem Sets
Documented Problem
Content
Teaching-Learning
Activities
Assessment Tasks
Solution
Gapped Lecture
Problem Sets
Documented Problem
Solution
Reflective Exercises
Campbell, M.K. and S.O. Farrell. (2012). Biochemistry. 7th ed. BROOKS/COLE CENGAGE Learning
Berg, J., J. Tymoczko and L. Stryer. (2012). Biochemistry. 7th ed. New York: W.H. Freeman and Co.
Devlin, T.M. (2010). Textbook of Biochemistry with Clinical Correlations. 7th ed. New York: Wiley-Liss.
Mathews, C.K., K.E. van Holde and K.G. Ahern. (2013). Biochemistry. 4th ed. San Francisco: Addison Wesley Longman, Inc.
Pratt, C.W. and Cornely K. (2013). Essential Biochemistry 3rd ed. New Jersey: John Wiley & Sons
Sylianco, C.L. and L. Sylianco-Wu. Biochemistry 4th ed. Quezon City: Aurum Technical Books
Voet, D., Voet, J.G., Pratt C.W. (2013). Principles of Biochemistry 4th ed. Singapore Pte. Ltd.: John Wiley & Sons
http://www.academic.cengage.com
http://www.wiley.com
GRADING SYSTEM:
The final grade is computed as 30% monthly, 35 % preliminary and 35% finals. The grade is composed of 60% lecture and 40% laboratory per
grading period. The lecture and laboratory grades are computed as follows:
Departmental Examination
Quizzes
Class Standing (Attendance/ Performance/Conduct)
Formal Reports
Pre-Lab Assignment
Data Sheet
Post-Lab Assignment
Total
Lecture (%)
50
40
10
------------------------100
Laboratory (%)
30
30
10
15
5
5
5
100
WEEK
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
CONTENT
Biochemistry and the Organization of Cells
Amino Acids and Proteins
Protein Isolation, Purification, and Characterization Techniques
Enzymes: Structure and Function
Enzymes: Mechanism and Control
MONTHLY
Nucleic Acids: How Structure Conveys Information
Replication: Biosynthesis of Nucleic Acids
Transcription of the Genetic Code: The Biosynthesis of RNA
Protein Synthesis: Translation of the Genetic Message
Mutation and Repair Mechanisms
PRELIMS
Nucleic Acid Biotechnology Techniques
Carbohydrates: Nomenclature, Classification and Function
Lipids: Nomenclature, Classification and Function
Glycolysis; Storage Mechanisms and Control in Carbohydrate Metabolism; The Citric Acid Cycle
Electron Transport and Oxidative Phosphorylation; Lipid Metabolism
FINALS