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Original Article
ABSTRACT
INTRODUCTION
Department of Pharmacology and Toxicology, College of Veterinary Science and Animal Husbandry,
Kuthulia, Rewa-486 001, Madhya Pradesh, India, *E-mail: drnitesh_kumar01@yahoo.co.in
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Figure 1. Plasma concentrations of W. somnifera following a single oral dose of 500 mg/kg in healthy
buffalo calves.
Table 1. Kinetic parameters of W. somnifera following a single oral administration of 500 mg/kg in healthy
calves.
Parameter (Unit)
(h-1)
t1/2 (h)
AUC (mg/ml.h)
AUMC(mg/ml.h2)
MRT (h)
Vdss (L/kg)
ClB (L/kg/h)
Mean S.E.M.
0.74 0.025
0.92 0.032
181.44 8.84
246.2617.66
1.34 0.045
3.68 0.12
2.78 0.12
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REFERENCES
Arora, S., S. Dhillon, G. Rani and A. Nagpal.
2004. The in vitro antibacterial/synergistic
activities of Withania somnifera extracts.
Fitoterapia, 75(3-4): 385-388.
Jaffer, H.J. and A.L.M. Jawad. 1998. Evaluation of
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