Sunteți pe pagina 1din 132

!

!
!
!
!
!
!
PHYSIOLOGY!MULTIPLE!CHOICE!QUESTIONS!

16.

Two of the chambers of the heart have relatively thin walls, one has thick walls and one has very thick
walls. What is the relative thickness of the walls of each of the chambers?
Thin walls

17.

18.

19.

M00/410/H(1)

Thick walls

Very thick walls

A.

left and right ventricles

left atrium

right atrium

B.

left and right ventricles

right atrium

left atrium

C.

left and right atria

left ventricle

right ventricle

D.

left and right atria

right ventricle

left ventricle

Why is infection with HIV (human immunodeficiency virus) associated with many different symptoms?
A.

People infected with HIV have different lifestyles.

B.

HIV attacks many different cells in the body causing many of the bodys systems to stop functioning
properly.

C.

The immune system stops functioning properly so many different disease-causing organisms can
invade the body.

D.

People infected with HIV do not always develop AIDS.

How is the loss of heat from exposed parts of the human body such as fingers, toes and nose reduced in
cold weather?
A.

Less blood flows to these parts of the body.

B.

Capillaries move further away from the skin in exposed parts.

C.

Heat is generated elsewhere in the body by shivering.

D.

The fat layer becomes thinner.

What is placed into the uterus, after the process of in vitro fertilisation (IVF)?
A.

Eggs

B.

Sperm

C.

Embryos

D.

Fetuses

220-180

Turn over

20.

21.

Which hormones control the contraction of the muscle in the uterus wall?
A.

Oestrogen inhibits it and progesterone stimulates it.

B.

Progesterone inhibits it and oxytocin stimulates it.

C.

Oxytocin inhibits it and FSH stimulates it.

D.

FSH inhibits it and oestrogen stimulates it.

What are characteristics of animal cells during mitosis and cytokinesis but not plant cells?
Mitosis

22.

23.

M00/410/H(1)

Cytokinesis

A.

Centrioles present

Cell plate forms

B.

Centrioles absent

Cell plate forms

C.

Centrioles present

Cell membrane pulled inwards at the equator

D.

Centrioles absent

Cell membrane pulled inwards at the equator

What are the differences between introns and exons?


A.

Introns are translated but exons are not

Introns are excised from mRNA


but exons remain part of it

B.

Exons are translated but introns are not

Exons are excised from mRNA


but introns remain part of it

C.

Introns are translated but exons are not

Exons are excised from mRNA


but introns remain part of it

D.

Exons are translated but introns are not

Introns are excised from mRNA


but exons remain part of it

The amino acid leucine can be coded for by six different codons. How many different kinds of tRNA
could bind to it?
A.

Only one

B.

Not more than six

C.

Twelve

D.

Eighteen

220-180

13

36.

37.

38.

39.

M00/410/H(1)

What is the function of each of the tendons in the human elbow joint?
A.

Reducing friction between the humerus and the radius and ulna

B.

Sealing the joint to hold in the synovial fluid

C.

Transmitting force from a muscle above the joint to a bone below the joint

D.

Preventing damage to the joint by acting as a shock absorber

What process moves toxic waste products from the blood to the dialysis fluid in a kidney dialysis
machine?
A.

Active transport

B.

Diffusion

C.

Osmosis

D.

Ultrafiltration

What part of the human body has the same function as the spongy mesophyll layer in a leaf?
A.

Alveoli in the lungs

B.

Erythrocytes in the blood

C.

Villi in the small intestine

D.

Sweat glands in the skin

Which conditions will cause the most rapid transpiration in a terrestrial, mesophytic plant?
A.

No wind

20 C

0 % humidity

bright light

B.

Strong wind

20 C

100 % humidity

bright light

C.

Strong wind

10 C

0 % humidity

darkness

D.

No wind

10 C

100 % humidity

darkness

220-180

Turn over

8
16.

17.

18.

19.

M01/410/H(1)

What are the products of the reactions catalysed by the enzymes shown in the table?
Lipases

Proteases

A.

lactic acid

polypeptides

B.

fatty acids

amino acids

C.

nucleic acids

hydrochloric acid

D.

triglycerides

polysaccharides

How does heart muscle contraction differ from the contraction of other muscles in the human body?
A.

It can contract without stimulation from nerves or hormones.

B.

It is stimulated to contract by hormones but not nerves.

C.

It is stimulated to contract by nerves but not hormones.

D.

Nerves speed up its rate of contraction but hormones slow it down.

What is the function of phagocytic leucocytes?


A.

To form a barrier against infection.

B.

To move to sites of infection and ingest microbes.

C.

To divide by mitosis to produce more leucocytes.

D.

To secrete platelets.

The kidney carries out the process of excretion by producing urine, which passes out of the body. What is
contained in urine?
A.

Toxic waste products of metabolism.

B.

Indigestible foods and harmful bacteria.

C.

Excess glucose and amino acids.

D.

Water and plasma proteins.

221-134

9
20.

21.

22.

23.

M01/410/H(1)

What does amniocentesis involve?


A.

Removal of amniotic fluid, culturing of cells and karyotyping.

B.

Bursting of the amniotic sac before childbirth.

C.

Bursting of the amniotic sac, removal of embryos and resealing of the amniotic sac.

D.

Production of amniotic fluid to protect the fetus.

In which cells can mitosis occur?


A.

Haploid only.

B.

Diploid only.

C.

Haploid and diploid only.

D.

Haploid, diploid and polyploid.

What happens in the process of splicing mRNA in cells?


A.

Addition of nucleotides to the 5' end of the mRNA.

B.

Addition of nucleotides to the 3' end of the mRNA.

C.

Removal of exons from the initial mRNA transcript.

D.

Removal of introns from the initial mRNA transcript.

What are the special features of allosteric enzymes that are controlled by feedback inhibition by
end-products?
Position in a
metabolic pathway

Number of
binding sites

A.

At the beginning

B.

At the end

C.

At the beginning

D.

At the end

221-134

Turn over

13
32.

33.

34.

35.

M01/410/H(1)

Which characteristic feature is possessed by angiospermophytes but not by coniferophytes?


A.

Leaves

B.

Seeds

C.

Xylem

D.

Flowers

Which structure is used for locomotion in the earthworms but not in arthropods, bony fishes or birds?
A.

Muscles attached to a rigid skeleton

B.

Chaetae

C.

Antagonistic muscles

D.

Jointed legs

Which type of membrane protein is required for transmission of the nerve impulse along the axon?
A.

Channel proteins

B.

Carrier proteins

C.

Receptor proteins

D.

Enzymes

What is the function of the cartilage in the elbow joint?


A.

To reduce friction

B.

To join bones together at the joint

C.

To join the muscles to the bones

D.

To act as a lubricant

221-134

Turn over

14
36.

37.

38.

How does the composition of the blood in the renal artery and the renal vein differ?
A.

The renal artery contains less glucose than the renal vein.

B.

The renal artery contains more carbon dioxide than the renal vein.

C.

The renal vein contains less oxygen then the renal artery.

D.

The renal vein contains more urea than the renal artery.

Which process is used in renal dialysis by kidney machines?


A.

Ultrafiltration

B.

Passive diffusion

C.

Active transport

D.

Carrier-assisted diffusion

What structural adaptation is found in hydrophytes but not in xerophytes?


A.

Leaves reduced to spines

B.

Thick waxy cuticles

C.

Reduced root system

D.

Hairy leaves

221-134

M01/410/H(1)

8
15.

16.

17.

M02/410/H(1)+

Which products are formed by the action of the enzymes listed?


Protease

Amylase

A.

Amino acids

Maltose

B.

Dipeptides

Disaccharides

C.

Proteins

Starch

D.

Polypeptides

Glucose

What are the states of the valves when the ventricles are relaxed?
Atrio-ventricular valves

Semilunar valves in the arteries

A.

Open

Open

B.

Open

Closed

C.

Closed

Open

D.

Closed

Closed

Where are the chemoreceptors that detect the changes in blood pH and levels of glucose found?
Changes in blood pH

Changes in blood glucose

A.

Brain stem

Small intestine

B.

Carotid vein

Liver

C.

Carotid artery

Pancreas

D.

Venae cavae

Liver

222-134

9
18.

19.

M02/410/H(1)+

Chorionic villus sampling is a prenatal test. What is the sample?


A.

Tissue from the amnion

B.

Fluid from the amniotic sac

C.

Blood from the umbilical artery

D.

Tissue from the placenta

What changes occur prior and during labour?


(m = increase, o= decrease)
Nerve impulses
from the cervix

Levels of blood
progesterone

Levels of blood
oxytocin

A.

B.

C.

D.

222-134

Turn over

14
30.

31.

M02/410/H(1)+

What is the sequence of processes leading to fertilisation?


A.

Acrosome reaction, cortical reaction, egg membrane penetration

B.

Egg membrane penetration, acrosome reaction, cortical reaction

C.

Acrosome reaction, egg membrane penetration, cortical reaction

D.

Cortical reaction, acrosome reaction, egg membrane penetration

The diagram below shows the immune system identifying an infected cell in the body.

Infected
cell
MHC molecules

Cytotoxic
T-cell

What is the structure labelled I?


A.

Antigen

B.

Antibody

C.

IgA

D.

IgM

222-134

15
32.

33.

34.

M02/410/H(1)+

What types of agent cause the diseases listed in the table?


Measles

Diphtheria

Tetanus

A.

Virus

Bacterium

Bacterium

B.

Virus

Virus

Virus

C.

Bacterium

Bacterium

Bacterium

D.

Bacterium

Virus

Virus

An organism has cell walls of chitin, no chlorophyll, stores carbohydrate as glycogen and reproduces by
means of spores without flagella. What is its kingdom?
A.

Protoctista

B.

Plantae

C.

Fungi

D.

Prokaryotae

Which list shows four levels of taxa in decreasing order of hierarchy?


A.

Family

Class

Genus

Order

B.

Order

Family

Genus

Class

C.

Order

Class

Family

Genus

D.

Class

Order

Family

Genus

222-134

Turn over

16
35.

M02/410/H(1)+

What is the sequence of events when a nerve impulse reaches the synaptic knob of a neuromuscular
junction?
I.

Synaptic vesicles release neurotransmitter

II.

Ca 2 ions enter the synaptic knob

III.

Neurotransmitter attaches to receptors on the muscular membrane(sarcolemma)

IV. Na + ions enter the muscular membrane

36.

A.

I, II, III, IV

B.

II, I, III, IV

C.

I, IV, II, III

D.

IV, II, I, III

The diagram below shows part of an actin filament of skeletal muscle.


II
III

What are the names of the labelled parts?


I

II

III

A.

Actin

Tropomyosin

Troponin

B.

Tropomyosin

Actin

Troponin

C.

Actin

Troponin

Tropomyosin

D.

Troponin

Actin

Tropomyosin

222-134

17
37.

Which structure of the kidney responds to ADH by reabsorbing water?


A.

Proximal convoluted tubule

B.

Loop of Henle

C.

Glomerulus

D.

Collecting duct

Which processes in angiospermophytes involve active transport?

38.

39.

M02/410/H(1)+

I.

Mineral ion uptake

II.

Translocation

III.

Transpiration

A.

I and II only

B.

I and III only

C.

II and III only

D.

I, II and III

What are the functions of xylem in angiospermophytes?


I.

Physical support

II.

Passive transport of water and minerals

III.

Active transport of carbohydrates

A.

I, II and III

B.

I and II only

C.

II and III only

D.

I and III only

222-134

Turn over

10
25.

M03/410/H(1)+

In garden peas, the pairs of alleles coding for seed shape and seed colour are unlinked. The allele for
smooth seeds (S) is dominant over the allele for wrinkled seeds (s). The allele for yellow seeds (Y) is
dominant over the allele for green seeds (y).
If a plant of genotype Ssyy is crossed with a plant of genotype ssYy, which offspring are recombinants?

26.

27.

28.

A.

SsYy and Ssyy

B.

SsYy and ssYy

C.

SsYy and ssyy

D.

Ssyy and ssYy

What constitutes a linkage group?


A.

Genes carried on the same chromosome

B.

Genes whose loci are on different autosomes

C.

Genes controlling a polygenic characteristic

D.

Alleles for the inheritance of ABO blood groups

Where would a digestive enzyme with an optimum pH of 2 be found?


A.

Large intestine

B.

Small intestine

C.

Stomach

D.

Pancreas

Which process decreases when the human body temperature decreases?


A.

Blood flow to the internal organs

B.

Secretion of sweat

C.

Secretion of insulin

D.

Shivering

223-134

11
29.

30.

M03/410/H(1)+

A synthetic hormone, syntocin, has the same effect on the body as oxytocin. For what purpose would
syntocin be used?
A.

Control of blood glucose levels

B.

Inhibition of the menstrual cycle

C.

Regulation of the heart rate

D.

Stimulation of uterine contraction

Which chamber pumps blood to the lungs?


II
I

III
IV

I
II

III

31.

A.

B.

II

C.

III

D.

IV

IV

Which process results in inhalation?


A.

An increase in volume of the chest cavity

B.

An increase in pressure in the chest cavity

C.

Relaxation of the external intercostal muscles

D.

Relaxation of the diaphragm

223-134

Turn over

12
32.

33.

34.

M03/410/H(1)+

Which of the following are barriers against the entry of pathogens into the body?
I.

Skin

II.

Mucous membranes

III.

Phagocytic leucocytes

A.

I only

B.

I and II only

C.

II and III only

D.

I, II and III

What is the correct sequence of events during blood clotting?


A.

Thrombin formation

clotting factor release

B.

Thrombin formation

fibrin formation

C.

Clotting factor release

fibrin formation

D.

Clotting factor release

thrombin formation

Which cell destroys viral-infected cells?


A.

Macrophage

B.

T-helper

C.

B-lymphocyte

D.

Cytotoxic T-cell

223-134

fibrin formation

clotting factor release


thrombin formation
fibrin formation

13
35.

M03/410/H(1)+

The diagram below shows the structure of testis tissue as seen using a light microscope.
Which is the primary spermatocyte?
A.
B.
C.

D.

36.

The diagram below shows a human elbow joint.

IV
III
II

Which response correctly identifies the ulna and the extensor muscle?
Ulna

Extensor muscle

A.

III

B.

IV

C.

II

IV

D.

II

III

223-134

Turn over

14
37.

38.

M03/410/H(1)+

Which substances are found in the glomerular filtrate but are usually absent in urine?
A.

Amino acids and glucose

B.

Water, pigments and salts

C.

Urea and hormone metabolites

D.

Large plasma proteins and red blood cells

The diagrams below show the distribution of tissues in the root and in the leaf of a dicotyledonous plant.
II

III

IV
upper

lower
Root

Leaf

Which tissues are phloem?

39.

A.

I and III only

B.

I and IV only

C.

II and III only

D.

II and IV only

Which response describes uptake of mineral ions into roots?


Movement of ions

Need for a
membrane protein

ATP requirement

A.

Following a concentration gradient

Yes

Yes

B.

Against a concentration gradient

Yes

Yes

C.

Following a concentration gradient

No

Yes

D.

Against a concentration gradient

No

Yes

223-134

9
18.

19.

20.

M04/411/H(1)+

Which of the following structures help the absorption of food by the small intestine?
I.

Capillary networks

II.

Villi

III.

Microvilli

IV.

Membrane proteins

A.

I and II only

B.

II and III only

C.

II, III and IV only

D.

I, II, III and IV

Which hormone affects the heart beat?


A.

Glucagon

B.

Insulin

C.

Adrenalin

D.

Oxytocin

Why do antibiotics kill bacteria but not viruses?


A.

Antibiotics stimulate the immune system against bacteria but not viruses

B.

Viruses have a way of blocking antibiotics

C.

Viruses are too small to be affected by antibiotics

D.

Viruses do not have a metabolism

224-134

Turn over

9
18.

19.

20.

M04/411/H(1)+

Which of the following structures help the absorption of food by the small intestine?
I.

Capillary networks

II.

Villi

III.

Microvilli

IV.

Membrane proteins

A.

I and II only

B.

II and III only

C.

II, III and IV only

D.

I, II, III and IV

Which hormone affects the heart beat?


A.

Glucagon

B.

Insulin

C.

Adrenalin

D.

Oxytocin

Why do antibiotics kill bacteria but not viruses?


A.

Antibiotics stimulate the immune system against bacteria but not viruses

B.

Viruses have a way of blocking antibiotics

C.

Viruses are too small to be affected by antibiotics

D.

Viruses do not have a metabolism

224-134

Turn over

10
21.

22.

M04/411/H(1)+

Which of the following is an effect of HIV on the human body?


A.

It reduces the number of erythrocytes in the blood

B.

It reduces the number of platelets in the blood

C.

It increases the amount of plasma in the blood

D.

It reduces the number of lymphocytes in the blood

In thermoregulation, what would happen over a short period of time in each of these areas, if a person was
placed in water at 15 C ?
Peripheral circulation

Sweat glands

Liver

Skeletal muscle

A.

Increased blood flow

Increased secretion

Decreased temperature

Decreased shivering

B.

Decreased blood flow

Decreased secretion

Decreased temperature

Increased shivering

C.

Decreased blood flow

Increased secretion

No change in temperature

Increased shivering

D.

Decreased blood flow

Decreased secretion

No change in temperature

Increased shivering

224-134

11
23.

M04/411/H(1)+

The diagram below shows the uterus of a pregnant woman.

I
II

III
IV

[Source: adapted from M B V Roberts (1986), Biology for Life, Nelson, page 348]

Where are samples taken from in amniocentesis?

24.

A.

B.

II

C.

III

D.

IV

The diagram below shows a nucleosome.

X
[Source: National Health Museum Graphics Gallery, www.accessexcellence.org/AB/GG/nucleosome.html]

What is structure X?
A.

DNA

B.

RNA

C.

Histone

D.

Deoxyribose

224-134

Turn over

14
29.

30.

31.

M04/411/H(1)+

When does recombination take place?


A.

Only when linked genes cross over

B.

When non-linked genes cross over and when linked genes show independent assortment

C.

Only when linked genes show independent assortment

D.

When non-linked genes show independent assortment and when linked genes show crossing over

A polygenic character is controlled by two genes each with two alleles. How many different possible
genotypes are there for this character?
A.

B.

C.

D.

16

What is the sequence of events in spermatogenesis?


A.

growth

meiosis

mitosis

differentiation

B.

mitosis

growth

meiosis

differentiation

C.

mitosis

meiosis

differentiation

growth

D.

meiosis

mitosis

growth

differentiation

224-134

15
32.

33.

M04/411/H(1)+

Which of the following parts of the male reproductive system contribute to the production of semen?
I.

Epididymis

II.

Seminal vesicle

III.

Bladder

IV.

Prostate

A.

II only

B.

II and IV only

C.

I, II and IV only

D.

I, II, III and IV

Where is human chorionic gonadotrophin (HCG) produced?


A.

Ovary

B.

Anterior pituitary

C.

Embryo

D.

Posterior pituitary

224-134

Turn over

16
34.

M04/411/H(1)+

Which curve shows the response of the immune system to a vaccine, followed by an infection?
A.

B.

Level of
antibody

Level of
antibody

Time

Time

Time

Level of
antibody

Level of
antibody

V = Vaccination

Time

I = Infection

What are the sequence of events at synaptic transmission?


I.

Neurotransmitter released

II.

Ca2+ enters synaptic knob

III.

Neurotransmitter binds with receptor

IV.

Action potential opens Ca2+ channels

A.

I, II, III, IV

B.

IV, II, I, III

C.

I, III, IV, II

D.

IV, II, III, I

224-134

D.

C.

35.

17
36.

37.

38.

M04/411/H(1)+

What is required to form a blood clot?


I.

Platelets

II.

Clotting factors

III.

Antibodies

IV.

Fibrinogen

A.

I and II only

B.

I, II and III only

C.

I, II and IV only

D.

I, II, III and IV

Where in the kidney does ultrafiltration take place?


A.

Glomerulus

B.

Loop of Henl

C.

Proximal tubule

D.

Collecting ducts

Which of the following are moved by active transport in the kidneys?


I.

Glucose

II.

Water

III.

Salts

IV.

Proteins

A.

I only

B.

I and II only

C.

I and III only

D.

I, II, III and IV

224-134

Turn over

8
19.

M04/412/H(1)+

Which of the following is correct regarding the enzymes listed in the table?
Enzyme
Amylase

20.

Lipase

Protease

A.

Substrate

polysaccharide

emulsified fat

dipeptide or polypeptide

B.

Substrate

emulsified fat

dipeptide or polypeptide

polysaccharide

C.

Product

amino acids

small polysaccharides or
monosaccharides

fatty acids and glycerol

D.

Product

small polysaccharides or
monosaccharides

amino acids

fatty acids and glycerol

The diagram shows how the body regulates glucose levels in the blood.
Glucose increase

X released

Glucose
normal

Y released

What is Y?
A.

Amylase

B.

Insulin

C.

Glucagon

D.

Glycogen

224-137

Glucose decrease

9
21.

22.

M04/412/H(1)+

What is transported by the blood?


I.

Carbon dioxide

II.

Antibodies

III.

Urea

A.

I only

B.

I and II only

C.

II and III only

D.

I, II and III

Which features of alveoli make them well suited to gas exchange?


I.

Dense arterial network

II.

Moist lining

III.

Walls consisting of a single layer of flattened cells

A.

I and II only

B.

I and III only

C.

II and III only

D.

I, II and III

224-137

Turn over

10
23.

M04/412/H(1)+

What are the structures labelled I, II and III in the diagram below?

III

I
II

II

A.

Oesophagus

Bronchiole

Ribs

B.

Trachea

Oesophagus

Bronchus

C.

Oesophagus

Trachea

Lung

D.

Trachea

Bronchus

Lung

224-137

III

14
32.

33.

Where does human fertilization most frequently occur?


A.

Ovary

B.

Oviduct

C.

Uterus

D.

Vagina

Which part of the structure below is most directly involved in the acrosome reaction?
A

34.

35.

M04/412/H(1)+

Which type of immunity usually results from vaccination?


A.

active, natural

B.

active, artificial

C.

passive, natural

D.

passive, artificial

Which type of cell is responsible for secondary immune responses to a pathogen?


A.

Cytotoxic T-cells

B.

Phagocytes

C.

Macrophages

D.

Memory cells

224-137

15
36.

Which structure is responsible for passing messages directly to effector organs?


A

37.

38.

M04/412/H(1)+

The movement of which ion initiates an action potential?


A.

Calcium

B.

Magnesium

C.

Sodium

D.

Potassium

Which structure transports blood with the highest concentration of urea?

224-137

Turn over

8
18.

M05/4/BIOLO/HPM/ENG/TZ1/XX+

In 1789 Gilbert White, a naturalist, observed eight breeding pairs of swifts (Apus apus) in the English
village of Selborne. Each pair of swifts produces two offspring on average per year. In 200 years this
should have produced 1030 swifts in the village of Selborne. A survey carried out in 1983 revealed only
12 breeding pairs in this village.
Which of the following possibilities could have prevented the numbers rising to 1030 ?

19.

I.

The number of nesting sites remained the same

II.

The food supply of the swifts remained constant

III.

Predatory birds in the area were exterminated

IV.

The climate become colder from 1789 onwards

A.

I only

B.

I and II only

C.

I, II and III only

D.

I, II and IV only

What are the characteristics of the lipase used in digestion?


Source

20.

Optimum pH

Substrate

A.

Pancreas

Lipid

B.

Small intestine

Lipid

C.

Stomach

Sucrose

D.

Liver

Lipid

Which is the correct sequence of blood flow in normal human circulation?


A.

pulmonary vein t right atrium t aorta t vena cava

B.

vena cava t pulmonary vein t aorta t right atrium

C.

vena cava t right atrium t pulmonary vein t aorta

D.

pulmonary vein t vena cava t aorta t right atrium

2205-6007

9
21.

22.

23.

M05/4/BIOLO/HPM/ENG/TZ1/XX+

How can human immunodeficiency virus (HIV) get transmitted from one human to another?
I.

By touching the skin of an infected person

II.

Through drinking contaminated water

III.

Through the exchange of body fluids

IV.

From mother to child across the placenta

A.

I and III only

B.

III and IV only

C.

I, III and IV only

D.

I, II, III and IV

Which cells secrete insulin?


A.

!-cells of the pancreas

B.

Cells of the liver

C.

"-cells of the pancreas

D.

Epithelial cells of the intestine

What does oxytocin control?


A.

Brain development of the fetus

B.

Onset of ovulation

C.

Stimulation of uterine contractions

D.

Implantation of the blastocyst

2205-6007

Turn over

14
32.

33.

34.

M05/4/BIOLO/HPM/ENG/TZ1/XX+

Which of the following are functions of the placenta?


I.

Gas exchange

II.

Stimulation of uterine contractions

III.

Secretion of progesterone

IV.

Secretion of estrogens

A.

I only

B.

III and IV only

C.

I, III and IV only

D.

I, II, III and IV

A blood clot contains a network of protein. What is the protein?


A.

Fibrin

B.

Fibrinogen

C.

Hemoglobin

D.

Thrombin

Monoclonal antibodies are produced by hybridoma cells. Hybridoma cells are formed by fusing tumor
cells with another cell type. What is this cell type?
A.

Phagocytes

B.

B-cells

C.

Stem cells

D.

T-cells

2205-6007

15
35.

36.

37.

M05/4/BIOLO/HPM/ENG/TZ1/XX+

In a nerve impulse, what happens at the site following the highest point of the action potential?
A.

Voltage-gated sodium ion channels open and Na + is pumped in.

B.

Voltage-gated sodium ion channels open and Na + diffuses out.

C.

Voltage-gated potassium ion channels open and K + is pumped out.

D.

Voltage-gated potassium ion channels open and K + diffuses out.

The diagram shows part of a muscle fibre. What will have occurred to bring the muscle fibre into this
state?

A.

The sarcoplasmic reticulum becomes polarized.

B.

Calcium ions move out of the sarcoplasmic reticulum.

C.

ADP and inorganic phosphate condense to form ATP.

D.

Troponin/tropomyosin protein complex blocks actin filament.

What is the relative toxicity of the following nitrogenous compounds?


A.

ammonia > uric acid > urea

B.

uric acid > urea > ammonia

C.

urea > uric acid > ammonia

D.

ammonia > urea > uric acid

2205-6007

Turn over

16
38.

39.

M05/4/BIOLO/HPM/ENG/TZ1/XX+

Which part of the nephron shown below is impermeable to water molecules?

A.

B.

II

C.

III

D.

IV

Which of the following is a correct comparison of the bryophytes and the filicinophytes?
Bryophytes

Filicinophytes

A.

Has a waxy cuticle

No waxy cuticle

B.

Has true leaves

Has scales

C.

Has rhizoids

Has roots

D.

Has woody tissue

No woody tissue

2205-6007

M05/4/BIOLO/HPM/ENG/TZ2/XX+

16. Which of the following may correctly identify the role(s) of some bacteria in an ecosystem?

A.

Autotroph only

B.

Autotroph and decomposer

C.

Decomposer and heterotroph

D.

Autotroph, decomposer and heterotroph

17. Which of the following can produce variation in a species?


I.

Mitosis

II.

Meiosis

III. Fertilization

A.

I only

B.

I and II only

C.

II and III only

D.

I, II and III

18. Which of the following is correct for a pathogen? yes no


Can be a virus

Can cause antibody response

Is antigenic

A.

B.

C.

D.

2205-6013

M05/4/BIOLO/HPM/ENG/TZ2/XX+

19. Which of the following is closely associated with lowering of high body temperature?

A.

Constriction of blood vessels in the skin

B.

Vasodilation of blood vessels in the skin

C.

Increased shivering

D.

Decreased sweat production

20. Which of the following correctly describes blood entering the pulmonary artery from the heart?
A.

Leaves left ventricle

Oxygenated

B.

Leaves right ventricle

Deoxygenated

C.

Leaves left ventricle

Deoxygenated

D.

Leaves right ventricle

Oxygenated

21. Which of the following correctly explains the functions of parts of the digestive system?
Stomach

Small intestine

Large intestine

A.

Digests proteins

Absorbs vitamin K

Absorbs water

B.

Absorbs water

Digests carbohydrates

Digests proteins

C.

Digests lipids

Digests proteins

Absorbs water

D.

Digests proteins

Absorbs glucose

Absorbs water

2205-6013

Turn over

M05/4/BIOLO/HPM/ENG/TZ2/XX+

22. Which of the following represents the blastocyst?


A.

B.

C.

D.

[Source: Campbell and Reece, Biology, (2002), 6th edition, Benjamin Cummings, pages 10031004]

23. A biochemist isolated and puried molecules needed for DNA replication. When some DNA was
added replication occurred, but the DNA molecules formed were defective. Each consisted of a
normal DNA strand paired with segments of DNA a few hundred nucleotides long. Which of the
following had been left out of the mixture?

A.

DNA ligase

B.

Helicase

C.

Nucleotides

D.

DNA polymerase

2205-6013

11

M05/4/BIOLO/HPM/ENG/TZ2/XX+

31. Where would meiosis occur in humans?


A.

Bone marrow

B.

Liver cells

C.

Uterus

D.

Ovary

32. What is the primary/main role of human chorionic gonadotrophin (HCG) in pregnancy?

A.

Maintains corpus luteum

B.

Reduces progesterone levels

C.

Development of the fetus

D.

Increases estrogen levels

33. Which of the following are attacked by cytotoxic T-cells?


I.

Cancer cells

II.

Bacteria

III. Virus infected cells

A.

I only

B.

I and III only

C.

II and III only

D.

I, II and III

2205-6013

Turn over

12

M05/4/BIOLO/HPM/ENG/TZ2/XX+

34. The diagram below is of a neuron.


II

III

[Source: adapted from S I Fox, Human Physiology, (1999), 6, McGraw-Hill, page 168]

Which of the following correctly name the structures labelled I, II and III?
I

II

III

A.

Nodes of Ranvier

Myelin sheath

Cell body

B.

Myelin sheath

Nodes of Ranvier

Cell body

C.

Myelin sheath

Cell body

Nodes of Ranvier

D.

Nodes of Ranvier

Cell body

Myelin sheath

35. When a motor neuron is at its resting potential, which of the following is correct for the concentration
of Na+ and K+ ions?
Inside neuron

Outside neuron

A.

K+ high

Na+ low

B.

Na+ low

K+ high

C.

K+ high

Na+ high

D.

Na+ high

K+ low

2205-6013

13

M05/4/BIOLO/HPM/ENG/TZ2/XX+

36. Which nitrogenous waste products are excreted by the following organisms?
Freshwater sh

Birds

Mammals

A.

Urea

Urea

Uric acid

B.

Ammonia

Uric acid

Ammonia

C.

Ammonia

Uric acid

Urea

D.

Uric acid

Ammonia

Urea

37. In diabetes mellitus, which compound is found in excess in the urine?


A.

Insulin

B.

Glucagon

C.

Protein

D.

Glucose

38. Which of the following help(s) in supporting a terrestrial woody plant?


I.

Xylem tissue

II.

Turgor pressure

III. Phloem tissue

A.

I only

B.

I and II only

C.

II and III only

D.

I, II and III

2205-6013

Turn over

10
22.

23.

Which is the correct sequence of events in a heart beat?


A.

Atria
contract

Ventricles
contract

B.

Atria
contract

Atrio-ventricular
valves close

C.

Atria
contract

D.

Ventricles
contract

Semi-lunar
valves close
Ventricles
contract

Semi-lunar
valves close

Ventricles
contract

Atrio-ventricular
valves close

Semi-lunar
valves open

Atria
contract

Atrio-ventricular
valves close

Semi-lunar
valves close

What are the characteristics of blood owing in arteries and veins?


Veins

A.

Slow velocity

Fast velocity

B.

High pressure

Low pressure

C.

Deoxygenated

Oxygenated

D.

Greater than 37

Less then 37

What makes the skin a barrier to infectious diseases?


A.

Impermeable cells which are frequently replaced

B.

Patrolling phagocytes

C.

Cells coated in antibody molecules

D.

Cells which secrete lysozyme enzyme

2206-6007

Atrio-ventricular
valves close

Arteries

24.

M06/4/BIOLO/HPM/ENG/TZ1/XX

11
25.

26.

M06/4/BIOLO/HPM/ENG/TZ1/XX

Which is the correct sequence of events during the phagocytosis of a bacterium by a leucocyte?
I.

Food vacuole forms

II.

Plasma membrane receptors detect antigen on the surface of the bacterium

III.

Lysosomes fuse with the food vacuole

IV.

Engulfs bacterium

A.

II

II

IV

III

B.

II

III

IV

C.

II

IV

III

D.

II

IV

III

Which labelled structures represent the epididymis and the prostate gland?

Epididymis

Prostate gland

A.

III

B.

II

III

C.

IV

D.

IV

2206-6007

Turn over

14
32.

M06/4/BIOLO/HPM/ENG/TZ1/XX

Which of the structures labelled in the diagram below provide nourishment for developing sperm
cells?

[Source: Freeman and Bracegirdle (1976), An atlas of histology, Heinemann, page 91]

33.

34.

Which hormone maintains the corpus luteum in the ovary of a woman at implantation?
A.

FSH

B.

LH

C.

HCG

D.

Progesterone

What is the difference between natural and articial immunity?


Natural

Articial

A.

Uses a vaccine

Uses synthetic antibodies

B.

Response to an infection

Response to a vaccination

C.

Memory cells formed

No memory cells formed

D.

Only active immunity

Only passive immunity

2206-6007

15
35.

36.

37.

M06/4/BIOLO/HPM/ENG/TZ1/XX

When an impulse arrives at a synapse which way do calcium ions move?


A.

Into the synaptic knob from the synaptic cleft

B.

Into the post synaptic nerve cell from the synaptic cleft

C.

Out from the synaptic knob into the synaptic cleft

D.

Out from the post synaptic nerve cell into the synaptic cleft

What are the characteristics of the skeletal systems of the following animals?
Earthworm

Bird

Insect

Bony sh

A.

Solid and internal

Solid and internal

Solid and internal

Fluid and internal

B.

Fluid and internal

Solid and internal

Fluid and internal

Solid and external

C.

Fluid and internal

Solid and internal

Solid and external

Solid and internal

D.

Solid and internal

Solid and external

Solid and internal

Solid and external

What are the main excretory products of birds?


I.

Urea

II.

Uric acid

III.

Ammonia

IV.

Carbon dioxide

A.

I and III only

B.

II and IV only

C.

III and IV only

D.

II, III, and IV only

2206-6007

Turn over

16
38.

M06/4/BIOLO/HPM/ENG/TZ1/XX

The diagram below shows part of the glomerulus from a kidney as seen under the electron microscope.
Which part is the basement membrane?
blood

ltrate

39.

40.

Xerophytes and hydrophytes are adapted to their environments. Which pair of adaptations is
correct?
Xerophytes

Hydrophytes

A.

Air spaces in roots

Water storage in roots

B.

No stomata

No stomata

C.

Stomata in pits

Thin or no cuticle

D.

Thick cuticle

Stomata in pits

Which direction does the phloem transport materials?


A.

Up the plant at night and down the plant during the day

B.

Up and down the plant all the time

C.

Up the plant only

D.

Down the plant only

2206-6007

9
21.

22.

23.

M06/4/BIOLO/HPM/ENG/TZ2/XX+

Which of the following changes occur with the onset of exercise?


A.

Increase in pH of blood

B.

Increase in rate of cellular respiration

C.

Decrease in rate of contraction of the diaphragm

D.

Decrease in carbon dioxide concentration of the blood

In which part of the digestive system is most water re-absorbed?


A.

The kidneys

B.

The stomach

C.

The small intestine

D.

The large intestine

Which of the following is part of the process of ventilation?


A.

Changes in the volume of the thoracic cavity

B.

Exchange of gases across the surface of the alveoli

C.

Exchange of gases across the surface of capillaries

D.

Cellular respiration

24. Which of the following occur(s) at birth in the mothers body?


I.

Increase in oxytocin

II.

Increase in uterine contractions

III.

Increase in levels of progesterone

A.

I only

B.

I and II only

C.

II and III only

D.

I, II and III

2206-6013

Turn over

10
25.

26.

M06/4/BIOLO/HPM/ENG/TZ2/XX+

Which of the following is regulated by positive feedback?


A.

Blood sugar

B.

Temperature

C.

Oxytocin levels

D.

Progesterone levels

Which of the following is a secondary sexual characteristic in human females?


A.

Increasing relative width of hips

B.

Presence of mammary glands

C.

Presence of a uterus

D.

Presence of a bladder

27.

According to the induced t model of enzyme function, which of the following statements is
correct?

A.

Active sites on enzymes are specic to a single substrate.

B.

The shape of the active site can be changed by the binding of an allosteric inhibitor.

C.

The binding of the substrate changes the shape of the active site slightly.

D.

Competitive inhibitors can change the shape of enzymes.

28.

Which of the following statements about pyruvate is true?


A.

It contains less energy than glucose per molecule.

B.

Every molecule of glucose is converted to one molecule of pyruvate.

C.

Pyruvate is produced in the mitochondria.

D.

Under aerobic conditions, pyruvate is converted to lactate.

2206-6013

11
29.

30.

31.

32.

M06/4/BIOLO/HPM/ENG/TZ2/XX+

At which stage of photosynthesis is light involved most directly?


A.

Reduction of NADP+ to NADPH2

B.

Chemiosmosis

C.

The synthesis of chlorophyll

D.

The photoactivation of chlorophyll

During which process are oxygen molecules directly involved during cellular respiration?
A.

Glycolysis

B.

Krebs cycle

C.

Oxidation of pyruvate to acetyl CoA

D.

Accepting electrons at the end of the electron transport chain

Which of the following is/are necessary to produce monoclonal antibodies?


I.

Tumour cells

II.

Plasma (B) cells

III.

Macrophages

A.

II only

B.

I and II only

C.

II and III only

D.

I, II and III

In which of the following structures does meiosis take place?


A.

Epididymis

B.

Prostate gland

C.

Testis

D.

Seminal vesicle

2206-6013

Turn over

12
33.

M06/4/BIOLO/HPM/ENG/TZ2/XX+

Membrane proteins are critical components of nerve function.


Which process in nerves does not require a membrane protein?

34.

35.

36.

A.

Diffusion of neurotransmitter

B.

Active transport of sodium

C.

Propagation of an action potential

D.

Binding of neurotransmitter

Which of the following has vascular tissue?


A.

Algae

B.

Chlorophyta

C.

Bryophyta

D.

Angiospermophytes

What treatment is most likely to lead to germination?


A.

Soaking the seeds in a solution of gibberellins

B.

Increasing CO2 concentration

C.

Increasing light intensity

D.

Dehydrating the seeds

Which of the following explains clonal selection?


A.

Memory cells are present at birth.

B.

Antigens activate specic immune responses.

C.

The body selects which antigens it will respond to.

D.

People with similar genes respond to antigens in a similar way.

2206-6013

7
17.

18.

19.

M07/4/BIOLO/HPM/ENG/TZ1/XX+

Two cellular activities that support human life are absorption and assimilation. What is needed for
assimilation but not for absorption?
A.

Enzymes to synthesize new molecules

B.

Blood capillaries

C.

Dissolved nutrients

D.

Microvilli

Which sequence of events correctly describes the destruction of pathogens in body tissues by
phagocytic leucocytes?
A.

amoeboid motion m endocytosis m chemical recognition m enzymatic digestion

B.

chemical recognition m amoeboid motion m enzymatic digestion m endocytosis

C.

amoeboid motion m chemical recognition m enzymatic digestion m endocytosis

D.

chemical recognition m amoeboid motion m endocytosis m enzymatic digestion

How many times does an oxygen molecule cross a plasma membrane when moving from inside an
alveolus to the hemoglobin of a red blood cell?
A.

Two

B.

Three

C.

Four

D.

Five

2207-6007

Turn over

8
20.

M07/4/BIOLO/HPM/ENG/TZ1/XX+

Women should periodically have a Pap smear test performed to detect cervical cancer. Which letter
indicates the cervix in the diagram below?

A
B
C
D

21.

In human embryo development, what is the approximate time span between fertilization and
implantation of the blastocyst?
A.

12 days

B.

7 days

C.

72 hours

D.

36 hours

2207-6007

12
31.

What is the origin and role of luteinizing hormone (LH) in spermatogenesis?


Origin

32.

M07/4/BIOLO/HPM/ENG/TZ1/XX+

Role

A.

Interstitial cells of testes

triggers rst meiotic division

B.

Pituitary gland

stimulates testosterone production

C.

Pituitary gland

triggers rst meiotic division

D.

Interstitial cells of testes

stimulates testosterone production

Why is human chorionic gonadotropin (HCG) important in early pregnancy?


A.

It is required for equal cell divisions in the growing embryo.

B.

It stimulates the ovary to continue production of estrogen and progesterone.

C.

It increases the rate of cell division in the embryo.

D.

It promotes growth of the inner cell mass within the embryo.

33.

Which sequence will result in the formation of a blood clot?

A.

damaged cells clotting factors thrombin brin

B.

damaged cells red blood cells clotting factors brinogen

C.

red blood cells clotting factors damaged cells brinogen

D.

red blood cells clotting factors thrombin brinogen

34.

What is the role of ligaments in the elbow joint?

A.

Attach biceps to radius

B.

Reduce friction between humerus, ulna and radius

C.

Hold humerus, ulna and radius in proper alignment

D.

Secrete synovial uid

2207-6007

13
35.

36.

M07/4/BIOLO/HPM/ENG/TZ1/XX+

Which division describes the central nervous system?


A.

Peripheral and central

B.

Voluntary and involuntary nerves

C.

Brain and spinal cord

D.

Sensory and motor nerves

Which process in the human body produces nitrogenous wastes?


A.

Osmoregulation

B.

Degradation of amino acids

C.

Cellular respiration

D.

Ultraltration

37.

What process do the kidney and kidney dialysis machines have in common?
A.

Endocytosis

B.

Active transport

C.

Diffusion

D.

Exocytosis

2207-6007

Turn over

N07/4/BIOLO/HPM/ENG/TZ0/XX+

18. The diagram below shows a simplied version of the carbon cycle.
CO2 in atmosphere
I
II
Fuels

Plants
Secondary
Consumer
Primary
Consumer

What processes are involved in the transfer of carbon at stages I and II?
I

19.

II

A.

combustion

photosynthesis

B.

photosynthesis

respiration

C.

combustion

respiration

D.

fossilization

respiration

Which of the following outlines the roles of the two hormones oxytocin and progesterone during
childbirth?
Oxytocin

Progesterone

A.

causes uterine contraction

level rises allowing oxytocin production

B.

level falls allowing progesterone production

causes uterine contraction

C.

stimulates oestrogen production

level falls allowing oxytocin production

D.

causes uterine contraction

level falls causing oxytocin production

8807-6001

9
20.

21.

22.

N07/4/BIOLO/HPM/ENG/TZ0/XX+

How do endocrine glands function when they are involved in homeostasis?


A.

They release hormones directly into the blood system.

B.

They release hormones through ducts to where they are used.

C.

They release digestive enzymes from the pancreas.

D.

They cause positive feedback in the bodys structures.

What is a pathogen?
A.

An organism that transmits a disease to humans

B.

A factor that causes lethal mutations

C.

A gene that makes a disease lethal

D.

An organism causing a disease

Why are there many different types of lymphocyte in the body?


A.

Each type can recognize one specic antibody and produces a specic antigen against it.

B.

Each type can recognize one specic antigen and produces a specic antibody against it.

C.

Each type can recognize one antigen and engulf it by phagocytosis.

D.

Each type can recognize one antibody and engulf it by phagocytosis.

8807-6001

Turn over

10
23.

24.

25.

N07/4/BIOLO/HPM/ENG/TZ0/XX+

What substances are normally removed from the body by the kidney?
I.

Excess salts

II.

Water

III.

Glucose

A.

I and II only

B.

I and III only

C.

II and III only

D.

I, II and III

What happens to the zygote immediately after fertilization?


A.

It remains in the uterus until placenta develops.

B.

It implants in the wall of the uterus.

C.

It divides by meiosis to form an embryo.

D.

It divides by mitosis to form a blastocyst.

What is absorption?
A.

Food entering the mouth and being chewed

B.

Food entering the stomach for digestion

C.

Taking digested food into the blood stream

D.

Making complex organic molecules in cells using digested foods

8807-6001

11
26.

N07/4/BIOLO/HPM/ENG/TZ0/XX+

What is in vitro fertilization?


A.

Fertilization using donated sperm

B.

Articial fertilization of an egg inside the body

C.

Fertilization of an egg outside the body

D.

Cloning technique to help couples conceive

27. What occurs in the induced t model for enzyme catalysed reactions?

28.

29.

A.

There is an exact t between a specic substrate and a specic enzyme.

B.

The enzyme can change shape to accommodate the substrate.

C.

The substrate can change its shape to t a number of enzymes.

D.

Other substrates can bind away from the active site.

What is a nucleosome?
A.

The protein core of a chromosome

B.

Histone proteins and DNA

C.

A chain of ribosomes

D.

The material within the nuclear membrane

What is an intron?
A.

The 3a m 5a strand of a DNA double helix

B.

The 5a m 3a strand of a DNA double helix

C.

A section of mRNA removed before translation

D.

A tRNA with a start anticodon

8807-6001

Turn over

13
32.

N07/4/BIOLO/HPM/ENG/TZ0/XX+

The diagram below shows a cell undergoing meiosis. What is this stage of meiosis?

A.

Anaphase I

B.

Prophase I

C.

Anaphase II

D.

Telophase II

33.

A pure breeding tall plant with smooth seeds was crossed with a pure breeding short plant with
wrinkled seeds. All the F1 plants were tall with smooth seeds. Two of these F1 plants were crossed
and four different phenotypes were obtained in the 320 plants produced.

How many tall plants with wrinkled seeds would you expect to nd?

34.

A.

20

B.

180

C.

60

D.

30

What is the function of the epididymis?


A.

Mucus production

B.

Production of nutrient fructose solution

C.

Storage of sperm during maturation

D.

Secretion of alkaline solution

8807-6001

Turn over

14
35.

36.

N07/4/BIOLO/HPM/ENG/TZ0/XX+

During oogenesis how many gametes are produced from one oogonium, the cell that starts to divide
to produce gametes?
A.

B.

C.

D.

Some infectious diseases are treated by injecting the patient with antibodies after they have been
exposed to the disease.
What type of immunity is this?

A.

articial and active

B.

articial and passive

C.

natural and passive

D.

natural and active

37.

When a nerve impulse is received by skeletal muscle it initiates a number of processes that result in
contraction. What are the roles of Ca2+, tropomyosin and ATP in contraction?
Ca2+

Tropomyosin

ATP

A.

binds to troponin

exposes binding site

binds to myosin

B.

binds to myosin

exposes binding site

binds to troponin

C.

binds to actin

exposes binding site

binds to myosin

D.

binds to troponin

binds to myosin

binds to actin

8807-6001

15
38.

39.

N07/4/BIOLO/HPM/ENG/TZ0/XX+

What part of the kidney is affected by anti-diuretic hormone (ADH)?


A.

Proximal convoluted tubule

B.

Loop of Henle

C.

Collecting duct

D.

Glomerulus

The diagram below shows a cross section through part of a dicotyledonous plant. What is the tissue
labelled I?

40.

A.

Cortex

B.

Phloem

C.

Endodermis

D.

Xylem

What route can water from the soil take as it passes through the root?
A.

Active transport

B.

Symplast pathway

C.

Translocation

D.

Endocytosis

8807-6001

8
18.

M08/4/BIOLO/HPM/ENG/TZ1/XX+

Which vessels correspond with the descriptions of I, II and III below?


I.

Thick outer layer of longitudinal collagen. Thick layers of circular elastic and muscle bres.
Narrow lumen.

II.

Thin outer layer of longitudinal collagen. Thin layers with a few circular elastic and muscle
bres. Wide lumen.

III. Wall consists of single layer of cells. Pores between cells that form the wall. Very narrow
lumen.
I

II

III

A.

artery

vein

capillary

B.

vein

artery

capillary

C.

artery

capillary

vein

D.

vein

capillary

artery

2208-6007

9
19.

M08/4/BIOLO/HPM/ENG/TZ1/XX+

Which processes are represented by the labels in the diagram below?

I
II

20.

II

A.

A phagocyte ingesting a microbe by


exocytosis.

Digestion of the microbe with the help of


the Golgi apparatus.

B.

A phagocyte ingesting a microbe by


endocytosis.

Digestion of the microbe with the help of


a lysosome.

C.

A phagocyte ingesting a microbe by


exocytosis.

Digestion of the microbe with the help of


a lysosome.

D.

A phagocyte ingesting a microbe by


endocytosis.

Digestion of the microbe with the help of


the Golgi apparatus.

Which type of urine would be produced in a human whose diet contains very small quantities of
protein or uid?
Urea Concentration

Salt Concentration

A.

High

Low

B.

Low

High

C.

High

High

D.

Low

Low

2208-6007

Turn over

10
21.

M08/4/BIOLO/HPM/ENG/TZ1/XX+

The diagram below shows the human male reproductive system and associated organs.

Which of the labelled structures indicate the bladder, prostate and urethra?
Bladder

Prostate

Urethra

A.

B.

C.

D.

2208-6007

11
22.

23.

M08/4/BIOLO/HPM/ENG/TZ1/XX+

What are the effect(s) of changing levels of FSH in the human menstrual cycle?
A.

Peak levels cause ovulation.

B.

Peak levels stimulate follicle development and estrogen secretion of the follicle.

C.

Peak levels stimulate follicle development and progesterone secretion of the follicle.

D.

Peak levels cause repair of the lining of the uterus.

Which are the correct directions of the following processes?


Replication

Transcription

Translation

A.

5 to 3

3 to 5

3 to 5

B.

3 to 5

5 to 3

5 to 3

C.

5 to 3

5 to 3

5 to 3

D.

3 to 5

3 to 5

3 to 5

2208-6007

Turn over

17
30.

31.

M08/4/BIOLO/HPM/ENG/TZ1/XX+

What constitutes a linkage group?


A.

Genes whose loci are on different chromosomes

B.

Genes carried on the same chromosome

C.

Genes controlling a polygenic characteristic

D.

Genes for the inheritance of ABO blood groups

What are the possible outcomes of recombination?


I.
II.
III.

A different combination of unlinked genes not seen in the parents


A different combination of linked genes not seen in the parents
The same combination of genes seen in the parents

A.

I and II only

B.

I and III only

C.

II and III only

D.

I, II and III

32.

Which correctly describes the role of the epididymis in semen production?

A.

Produces uid containing fructose to nurture sperm.

B.

Finishes maturation of sperm so that they are capable of swimming.

C.

Produces alkaline uid with minerals to protect sperm.

D.

Produces uid containing fructose and store mature sperm.

2208-6007

Turn over

18

M08/4/BIOLO/HPM/ENG/TZ1/XX+

33.

After fertilization what is the correct order of events?

A.

Embryo secretes HCG implantation of embryo in uterine wall stimulates corpus luteum
to grow

B.

Implantation of embryo in uterine wall stimulates corpus luteum to grow embryo secretes
HCG

C.

Implantation of embryo in uterine wall embryo secretes HCG stimulates corpus luteum
to grow

D.

Continued secretion of progesterone and estrogen embryo secretes HCG stimulates corpus
luteum to grow implantation of embryo in uterine wall

34. Colostrum, the rst milk produced by the mother after giving birth, also contains antibodies that can
be absorbed into the babys blood. What type of immunity is the baby acquiring from its mother?
A.

Passive

B.

Antigen

C.

Active

D.

Articial

35.

What is the correct order in the production of monoclonal antibodies?

A.

Isolate B-cells producing specic antibody inject antigens into animal fuse B-cells with
tumour cells harvest monoclonal antibodies.

B.

Inject antigens into animal isolate B-cells producing specic antibody fuse B-cells with
tumour cells harvest monoclonal antibodies.

C.

Isolate B-cells producing specic antibody fuse B-cells with tumour cells inject antigens
into animal harvest monoclonal antibodies.

D.

Inject antigens into animal fuse cultured B-cells with tumour cells isolate B-cells producing
specic antibody harvest monoclonal antibodies.

2208-6007

19
36.

37.

M08/4/BIOLO/HPM/ENG/TZ1/XX+

After depolorization what happens to restore the resting potential?


A.

Sodium channels open and sodium ions diffuse out of the neuron

B.

Potassium channels open and potassium ions diffuse into the neuron

C.

Potassium channels open and potassium ions diffuse out of the neuron

D.

Sodium channels open and sodium ions diffuse into the neuron

The diagram below shows part of a muscle bre. What parts are labelled I and II?
I

II

II

A.

Myosin laments

Actin laments

B.

Troponin laments

Tropomyosin laments

C.

Tropomyosin laments

Troponin laments

D.

Actin laments

Myosin laments

2208-6007

Turn over

7
16.

What is a factor that increases the greenhouse effect and what is a consequence of it?
Factor contributing to increases
in the greenhouse effect

17.

M08/4/BIOLO/HPM/ENG/TZ2/XX+

Consequence of the increased


greenhouse effect

A.

Increasing global temperatures

Rising sea levels

B.

Rising sea levels

Increasing global temperatures

C.

Increasing global temperatures

Burning fossil fuels to run air conditioning

D.

Increases in air travel

Increasing global temperatures

Which of the following structures increase the surface area for absorption of digested food in the
small intestine?
I.

Microvilli

II.

Protein pumps

III.

Villi

A.

I only

B.

I and III only

C.

II and III only

D.

I, II and III

2208-6013

Turn over

8
18.

M08/4/BIOLO/HPM/ENG/TZ2/XX+

What are the structures labelled I and II on the diagram of the heart?
I
II

19.

A.

I is the pulmonary artery and II is the atrio-ventricular valve.

B.

I is the pulmonary vein and II is the atrio-ventricular valve.

C.

I is the pulmonary artery and II is the semi-lunar valve.

D.

I is the pulmonary vein and II is the semi-lunar valve.

Why are antibiotics ineffective against viruses?


A.

Viruses do not have metabolic pathways for the antibiotic to target.

B.

Viruses have developed resistance to antibiotics.

C.

Viruses destroy T-lymphocytes before the antibiotic can work.

D.

Viruses mutate quickly when challenged by an antibiotic.

2208-6013

9
20.

M08/4/BIOLO/HPM/ENG/TZ2/XX+

What changes would occur if a person moved from a cold swimming pool to a very warm
changing room?
Transfer of heat in
blood to the skin

Temperature of
the skin

Rate of blood ow in
skin arterioles

A.

Decreases

Increases

Increases

B.

Increases

Decreases

Increases

C.

Increases

Increases

Decreases

D.

Increases

Increases

Increases

21. Do the levels of progesterone and FSH increase or remain low during the rst few days of the
menstrual cycle?
A.

Progesterone and FSH both remain low.

B.

Progesterone remains low but FSH increases.

C.

Progesterone increases but FSH remains low.

D.

Progesterone and FSH both increase.

22.

What happens during amniocentesis?

A.

The amniotic sac lls up with uid to prevent damage to the fetus.

B.

Amniotic uid is removed to obtain fetal cells for testing.

C.

The amniotic uid is replaced to avoid rejection problems with rhesus positive fetuses.

D.

Fluid is emptied from the amniotic sac during childbirth.

2208-6013

Turn over

12
28.

M08/4/BIOLO/HPM/ENG/TZ2/XX+

Humans are in blood group M, N or MN. The alleles for blood group M (M) and blood group N (N)
are co-dominant. Humans are also in blood group A, B, AB or O. The alleles controlling these
blood groups are IA, IB and i.
If two parents have the genotypes ii MM and IAi MN what is the ratio of possible phenotypes of
their offspring?

29.

30.

A.

9 group A, group M

3 group A, group N

3 group O, group M

1 group O, group N

B.

9 group O, group M

3 group O, group N

3 group A, group M

1 group A, group N

C.

3 group O, group M

3 group O, group MN

1 group A, group M

1 group A, group MN

D.

1 group A, group M

1 group A, group MN

1 group O, group M

1 group O, group MN

A cell replicates its DNA and then starts to divide by meiosis. What is the expected arrangement of
chromosomes if crossing over has taken place between the two genes shown?
A.

B.

C.

D.

What is the location and function of Sertoli cells?


Location

Function

A.

Seminiferous tubule

Feeding developing sperm

B.

Seminiferous tubule

Feeding interstitial cells

C.

Epididymis

Feeding developing sperm

D.

Epididymis

Feeding interstitial cells

2208-6013

13
31.

During fertilization in humans, where do the acrosome and the cortical reactions occur most often?
Acrosome reaction

32.

M08/4/BIOLO/HPM/ENG/TZ2/XX+

Cortical reaction

A.

Vagina

Uterus

B.

Uterus

Oviduct (fallopian tube)

C.

Oviduct (fallopian tube)

Uterus

D.

Oviduct (fallopian tube)

Oviduct (fallopian tube)

Which is the correct sequence of events when skin is cut and bleeding occurs?

I.

Thrombin is produced

II

Fibrinogen is converted into brin

III

Platelets release clotting factors

A.

I m II m III

B.

I m III m II

C.

III m II m I

D.

III m I m II

33. What causes articial active immunity?

A.

Deliberately exposing a child to a disease

B.

Secretion of antibodies in milk

C.

Inoculation with a vaccine

D.

Injection of monoclonal antibodies

2208-6013

Turn over

14
34.

M08/4/BIOLO/HPM/ENG/TZ2/XX+

Which ion is pumped into the axon of a neuron to help maintain the resting potential?
A.

Calcium (Ca2+ )

B.

Hydrogen (H+ )

C.

Potassium (K+ )

D.

Sodium (Na+ )

35. What structures are used in the locomotion of bony shes and birds, but not in the locomotion of
earthworms and arthropods?

A.

Antagonistic muscles

B.

Bones to which antagonistic muscles are attached

C.

Neurons to stimulate muscle contraction

D.

Fins or wings for swimming or ying

36. In which part of the nephron is the glucose concentration of the ltrate reduced?
A.

Distal convoluted tubule

B.

Proximal convoluted tubule

C.

Ascending limb of the loop of Henl

D.

Descending limb of the loop of Henl

2208-6013

15
37.

M08/4/BIOLO/HPM/ENG/TZ2/XX+

What structures are labelled I, II and III in the diagram of the kidney below?
I

III
II

38.

II

III

A.

Cortex

Medulla

Urethra

B.

Medulla

Pelvis

Ureter

C.

Cortex

Medulla

Ureter

D.

Medulla

Pelvis

Urethra

Which is an adaptation of hydrophytes?


A.

Water storage tissue

B.

Shallow but widely spreading roots

C.

Reduced thickness of cuticle

D.

Large numbers of stomata in the lower epidermis

2208-6013

Turn over

9
17.

N08/4/BIOLO/HPM/ENG/TZ0/XX+

The diagram below represents the human digestive system.

1
4
2
3

Which of the following correctly represents the labels?


Esophagus

Gall bladder

Small intestine

Pancreas

A.

B.

C.

D.

18. What are the characteristics of blood owing through most arteries and veins?
Arteries

Veins

A.

slow velocity

fast velocity

B.

high pressure

low pressure

C.

deoxygenated

oxygenated

D.

greater than 37 C

less than 37 C

8808-6001

Turn over

10
19.

20.

N08/4/BIOLO/HPM/ENG/TZ0/XX+

What will be an effect of HIV infection on the immune system?


A.

Antigens no longer bind to antibodies.

B.

Number of active lymphocytes is increased.

C.

Antibody production is limited.

D.

HIV patient will fall ill more frequently.

The graph below shows the blood glucose concentration of a patient after feeding at 07:00.
240
220
200
Blood glucose /
mg 100 ml1

180
160
140
120
100
05:00

07:00

09:00
11:00
Time of day

13:00

What describes the events between 07:00 and 09:00 and between 09:00 and 11:00?
Between 07:00 and 09:00

Between 09:00 and 11:00

A.

islet cells produce and secrete insulin

islet cells produce glucagon

B.

islet cells produce and secrete glucagon

islet cells produce and secrete insulin

C.

islet cells produce and secrete glucagon

islet cells produce and secrete insulin

D.

islet cells produce and secrete insulin

islet cells produce and secrete glucagon

8808-6001

11
21.

N08/4/BIOLO/HPM/ENG/TZ0/XX+

The diagram below shows the female reproductive system and associated organs.

Which of the labelled structures correctly identify the cervix, urethra and ovary?

22.

Cervix

Urethra

Ovary

A.

B.

C.

D.

Which sequence of events precedes birth?


A.

Progesterone levels increase, oxytocin decreases, uterine contractions increase,


oxytocin decreases further.

B.

Progesterone levels decrease, oxytocin increases, uterine contractions increase,


oxytocin increases further.

C.

Progesterone levels increase, oxytocin increases, uterine contractions decrease,


oxytocin decreases.

D.

Progesterone levels decrease, oxytocin decreases, uterine contractions decrease,


oxytocin decreases further.

8808-6001

Turn over

16
32.

Which of the following correctly describes features of spermatogenesis and oogenesis?


Spermatogenesis

33.

N08/4/BIOLO/HPM/ENG/TZ0/XX+

Oogenesis

A.

mitosis

meiosis

B.

completed during fertilization

completed during fertilization

C.

four sperm produced per meiosis

one egg produced per meiosis

D.

sperm production starts during


fetal development

early stages happen during fetal


development

Which materials are passed across the placenta from the fetus back to the mother?
A.

Carbon dioxide, urea, hormones and water

B.

Oxygen, minerals, urea and hormones

C.

Carbon dioxide, proteins, uric acid and water

D.

Oxygen, carbon dioxide, urea and hormones

34. Which of the following represent an example of both articial immunity and passive immunity?
A.

Antibodies passed across in colostrum

B.

Injection of antivenom used to treat snake bites

C.

Exposure to somebody who is ill with Chickenpox

D.

Immunization with a weakened form of a virus

8808-6001

17
35.

36.

N08/4/BIOLO/HPM/ENG/TZ0/XX+

What is(are) the use(s) of monoclonal antibodies in treatment and diagnosis?

I.

Targeting viral proteins

II.

Purication of interferon

III.

Tissue typing for transplants

A.

I only

B.

I and II only

C.

I and III only

D.

I, II and III

In the diagram of the motor neuron below what is indicated by the labels W, X, Y and Z?
W
X

A.

myelin sheath

dendrite

node of Ranvier

elongated axon

B.

myelin sheath

dendrite

elongated axon

node of Ranvier

C.

dendrite

myelin sheath

elongated axon

node of Ranvier

D.

dendrite

node of Ranvier

myelin sheath

elongated axon

8808-6001

Turn over

18

N08/4/BIOLO/HPM/ENG/TZ0/XX+

37. In the human elbow joint, what are the functions of synovial uid, cartilage and ligaments?
Synovial uid

38.

Ligaments

A.

reduces friction

lubricates the joint

links bone to bone

B.

lubricates the joint

reduces friction

links bone to bone

C.

reduces friction

links bone to bone

lubricates the joint

D.

lubricates the joint

links bone to bone

reduces friction

Which excretory product occurs in which group of organisms?


Carbon dioxide

39.

Cartilage

Uric acid

Oxygen

A.

mammals

birds

plants

B.

mammals

plants

birds

C.

plants

mammals

birds

D.

birds

plants

mammals

A plant has roots, leaves and short woody stems. The leaves are usually curled up during growth and
divided into leaets. They produce spores, usually on the underside of the leaves.
What type of plant could this be?
A.

Hydrophyte

B.

Filicinophyte

C.

Bryophyte

D.

Xerophyte

8808-6001

M09/4/BIOLO/HPM/ENG/TZ1/XX+

18. Which of the organisms AD, identied by the key below, represents an Annelid?

1. Shows bilateral symmetry


Does not show bilateral symmetry

go to 2
Cnidaria

2. Has a segmented body


Does not have a segmented body

go to 3
go to 4

3. Has jointed legs


Does not have jointed legs

A
B

4. Has a shell
Does not have a shell

C
D

19. Which of the following parts of the digestive system secrete proteases?
Stomach

Small Intestine

Large Intestine

A.

Yes

Yes

No

B.

Yes

No

Yes

C.

Yes

No

No

D.

No

No

No

20. Why are antibiotics effective against bacteria but not viruses?

A.

Viruses can hide inside host cells.

B.

Bacteria are recognized as pathogens but viruses are not.

C.

The enzymes of bacteria can be inhibited by antibiotics.

D.

Viruses are resistant to antibiotics.

2209-6007

Turn over

10

M09/4/BIOLO/HPM/ENG/TZ1/XX+

21. The diagram below represents the homeostatic control of body temperature. What does the part
labelled X represent?

core body
temperature
<37 C

muscles of skin
arteriole walls
skeletal muscles

NEGATIVE FEEDBACK
blood temperature

A.

Heart

B.

Kidney

C.

Pituitary

D.

Hypothalamus

2209-6007

return to
37 C

11

M09/4/BIOLO/HPM/ENG/TZ1/XX+

22. What are the structures labelled I and II on the diagram of the male reproductive system?

II

II

A.

Testis

Seminal vesicle

B.

Vas deferens

Testis

C.

Seminal vesicle

Epididymis

D.

Seminal vesicle

Prostate gland

23. What are the fundamental structural units of eukaryotic chromosomes?


A.

Nucleosomes

B.

Centromeres

C.

Histones

D.

Nucleoids

2209-6007

Turn over

16

M09/4/BIOLO/HPM/ENG/TZ1/XX+

35. Which of the following processes result in the production of recombinants?


I.

Crossing over between linked genes

II.

Reassortment of non-linked genes

III. Mutation

A.

I only

B.

I and II only

C.

I and III only

D.

I, II and III

36. What is required to produce monoclonal antibodies?


A.

T-lymphocytes and oocytes

B.

T-lymphocytes and early embryo cells

C.

B-lymphocytes and tumour cells

D.

B-lymphocytes and stem cells

2209-6007

M09/4/BIOLO/HPM/ENG/TZ2/XX+

10. If 15 % of a sample of DNA is thymine, what percentage of the DNA is guanine?


A.

15 %

B.

30 %

C.

35 %

D.

It cannot be determined from the information given.

11. On which molecule is a codon found?


A.

Polypeptide

B.

mRNA

C.

tRNA

D.

rRNA

12. What do all human males inherit from their mother?


I.

An X chromosome

II.

A Y chromosome

III. Mitochondrial DNA

A.

I and II only

B.

II only

C.

I and III only

D.

I, II and III

13. Which structure releases glucagon?


A.

cells of the pancreas

B.

cells of the pancreas

C.

Liver cells

D.

Hypothalamus

2209-6013

Turn over

M09/4/BIOLO/HPM/ENG/TZ2/XX+

14. Which muscle action is associated with an increase in the volume of the thoracic cavity during
inspiration?

A.

The diaphragm contracts.

B.

The external intercostal muscles relax.

C.

The internal intercostal muscles contract.

D.

The abdominal muscles contract.

15. When a pathogen is ingested by a phagocyte, which event occurs rst?


A.

T-cell activation

B.

Memory cell proliferation

C.

Antigen presentation by the phagocyte

D.

B-cell activation

2209-6013

M09/4/BIOLO/HPM/ENG/TZ2/XX+

16. Which of the following describes arteries?


A.

They have thick muscular walls.

B.

They usually contain valves.

C.

They carry blood towards the heart.

D.

They carry blood from the lungs.

17. What is the main function of the large intestine?


A.

Absorption of water

B.

Digestion of fats and proteins

C.

Absorption of nutrients

D.

Recycling of digestive enzymes

18.

To which group do sponges belong?

A.

Cnidaria

B.

Filicinophyta

C.

Porifera

D.

Mollusca

2209-6013

Turn over

10

M09/4/BIOLO/HPM/ENG/TZ2/XX+

24. In the following diagram of the kidney, which structure contains urine?
A
B
C
D

25. Which structure is acted upon by ADH (vasopressin)?


A.

Proximal convoluted tubule

B.

Bowmans capsule

C.

Loop of Henle

D.

Collecting duct

26. What is the distinction between highly repetitive DNA sequences and single-copy genes?

A.

The highly repetitive sequences have greater amounts of guanine.

B.

The highly repetitive sequences have greater amounts of cytosine.

C.

The highly repetitive sequences are not transcribed.

D.

The highly repetitive sequences are not replicated.

2209-6013

11
27.

M09/4/BIOLO/HPM/ENG/TZ2/XX+

Which of the cells labelled in the diagram below provides nourishment for developing sperm cells?

A
B

[Source: Freeman & Bracegirdle, An Atlas of Histology, (Heinemann: 1976) p. 91, Copyright holder unknown.]

28. What is the advantage of CAM (crassulacean acid metabolism) and other adaptations of xerophytes
in plants?

A.

It helps the plant to survive high humidity.

B.

It helps the plant prevent water loss.

C.

It helps the plant survive low light intensities.

D.

It helps the plant survive when there are low nutrients in soil.

29. Which plant hormone is responsible for the closing of the stomata?

A.

Gibberellic acid

B.

Abscisic acid

C.

Phytochromes

D.

Ethylene

2209-6013

Turn over

13

M09/4/BIOLO/HPM/ENG/TZ2/XX+

32. What structure within muscle tissue is surround by membrane and has multiple nuclei?

A.

Muscle bundle

B.

Muscle bre

C.

Myobril

D.

Sarcomere

33. Which of the following are features of the dicotyledonous plants?


I.

Parallel leaf veins

II.

Flower parts in groups of three

III. Two seed-leaves (cotyledons)

A.

III only

B.

II and III only

C.

I and II only

D.

I, II and III

34. Which of the following statements is true about enzymes?


A.

They are used up in the reactions they catalyse.

B.

Allosteric inhibitors bind to the active site.

C.

They lower the energy of activation for a reaction.

D.

They supply the energy of activation for a reaction.

2209-6013

Turn over

N09/4/BIOLO/HPM/ENG/TZ0/XX+

19. Pseudolarix amabilis produces seeds but not owers. Physcomitrella patens has leaves but not roots.
To which groups do they belong?
Pseudolarix amabilis

Physcomitrella patens

A.

coniferophyta

licinophyta

B.

licinophyta

angiospermophyta

C.

coniferophyta

bryophyta

D.

angiospermophyta

coniferophyta

20. The diagram below shows parts of the human digestive system.

Which points are linked by the small intestine?

A.

I and III

B.

II and III

C.

II and IV

D.

III and IV

8809-6001

N09/4/BIOLO/HPM/ENG/TZ0/XX+

21. What route does blood follow to supply oxygen to heart muscle?

A.

pulmonary vein m left atrium m left ventricle m aorta m coronary artery

B.

pulmonary vein m right atrium m right ventricle m aorta m coronary artery

C.

pulmonary artery m left atrium m left ventricle m aorta m coronary artery

D.

pulmonary artery m right atrium m right ventricle m aorta m coronary artery

22. What change occurs to the pressure and volume of the lungs when the external intercostal muscles
contract?

A.

Both pressure and volume increase.

B.

Pressure increases and volume decreases.

C.

Pressure decreases and volume increases.

D.

Both pressure and volume decrease.

23. The graph below shows changes in membrane potential in an axon during the passage of an
action potential. What is causing the decrease in membrane potential at point X?
X
0

Time

Membrane
potential /
mV

70

A.

Sodium ions entering the axon

B.

Potassium ions entering the axon

C.

Sodium ions leaving the axon

D.

Potassium ions leaving the axon

8809-6001

Turn over

10

N09/4/BIOLO/HPM/ENG/TZ0/XX+

24. What is the consequence of insufcient secretion of FSH in women?


A.

Embryo implantation fails because the uterus lining is too thin.

B.

Mature eggs (oocytes) are not produced.

C.

Menstruation starts before embryo implantation occurs.

D.

Progesterone secretion is inhibited.

8809-6001

16

N09/4/BIOLO/HPM/ENG/TZ0/XX+

36. What is a hypothesis in biology?


A.

An experiment that is used to test a theory

B.

An idea that cannot be tested experimentally

C.

A method used to prove a law

D.

A proposed explanation of observations

37. Which cells activate helper T-cells by antigen presentation?


A.

B-cells

B.

Bacteria

C.

Macrophages

D.

Plasma cells

38. What happens during muscle contraction?


A.

The number of light bands is reduced.

B.

The width of the dark bands is reduced.

C.

The lengths of the sarcomeres are reduced.

D.

Actin and myosin laments coil up.

39. The Bowmans capsule is a cup-shaped structure that is part of the nephron. What is the source of
glucose in the uid in the Bowmans capsule?

A.

Blood in the glomerulus

B.

Urine in the renal pelvis

C.

Filtrate in the distal convoluted tubule

D.

Interstitial uid in the medulla

8809-6001

17

N09/4/BIOLO/HPM/ENG/TZ0/XX+

40. The diagram below shows a human egg.

II

III

What are the structures labelled I, II and III?


I

II

III

A.

acrosomes

zona pellucida

follicle cells

B.

acrosomes

cell wall

sperm

C.

cortical granules

cell wall

sperm

D.

cortical granules

zona pellucida

follicle cells

8809-6001

10

M10/4/BIOLO/HPM/ENG/TZ1/XX+

19. Which of the following are used as evidence for evolution?


I.

Homologous structures

II.

Selective breeding of domesticated animals

III. Overproduction of offspring

A.

I and II only

B.

I and III only

C.

II and III only

D.

I, II and III

20. Which of the following is correct for lipase?


Substrate

Source

pH optimum

A.

triglycerides

pancreas

pH = 8

B.

fatty acids

small intestine

pH = 7

C.

triglycerides

small intestine

pH = 9

D.

fatty acids

pancreas

pH = 9

21. What prevents antibiotics from being effective against viruses?


A.

Viruses have a high rate of mutation.

B.

Viruses have no RNA.

C.

Viruses have no metabolism.

D.

Viruses have a protein shell that protects them.

2210-6007

11

M10/4/BIOLO/HPM/ENG/TZ1/XX+

22. The diagram below shows the human heart. What structures are indicated by the labels X, Y and Z?

Y
X

[Source: adapted from http://whyles.org/102spareparts/images/heart2.gif]

A.

left atrium

aorta

semi-lunar valve

B.

left atrium

aorta

atrio-ventricular valve

C.

right atrium

pulmonary artery

atrio-ventricular valve

D.

right atrium

pulmonary artery

semi-lunar valve

23. Which muscles contract to cause air to pass into the lungs through the trachea?

A.

Internal intercostal muscles and diaphragm

B.

Internal intercostal muscles and abdomen wall muscles

C.

External intercostal muscles and diaphragm

D.

External intercostal muscles and abdomen wall muscles

2210-6007

Turn over

12

M10/4/BIOLO/HPM/ENG/TZ1/XX+

24. The diagram below shows the changes in membrane potential during an action potential.

What occurs at the stages labelled 1 and 2?
+ 60

Membrane potential / mV

+ 40

Action potential
2

40

Threshold potential

60

Resting potential

100

0 1 2 3 4 5 6 7 8
Time / msec
1

2
+

A.

Na ions diffuse in;


inside becomes more positive

K ions diffuse out;


inside becomes more negative

B.

K+ ions diffuse out;


inside becomes more negative

Na+ ions diffuse in;


inside becomes more positive

C.

Na+ ions diffuse out;


inside becomes more negative

K+ ions diffuse out;


inside becomes more positive

D.

Na+ ions diffuse in;


inside becomes more positive

K+ ions diffuse in;


inside becomes more negative

25. What are the roles of testosterone in males?


A.

Stimulation of FSH production and growth in puberty

B.

Pre-natal development of genitalia and development of secondary sexual characteristics

C.

Development of genitalia and pre-natal secondary sexual characteristics

D.

Stimulation of FSH production and pre-natal development of secondary sexual characteristics

2210-6007

17

M10/4/BIOLO/HPM/ENG/TZ1/XX+

34. A test cross resulted in these recombinants:

tB

Tb

tb

tb

Which of the following was the parental test cross?


A.

B.

C.

D.

TB
tb
TB
tB
Tb
tB
TB
tb

tb
tb
tb
Tb
tb
tb
TB
tb

35. What occurs during the blood clotting process?


A.

Prothrombin is converted into thrombin which acts on brinogen.

B.

Prothrombin is converted into thrombin which acts on brin.

C.

Fibrinogen is converted into brin which acts on prothrombin.

D.

Fibrinogen is converted into brin which acts on thrombin.

2210-6007

Turn over

18

M10/4/BIOLO/HPM/ENG/TZ1/XX+

36. What is indicated by the letters X, Y and Z?


Z

X
Y
X

A.

sarcomere

myosin laments

actin laments

B.

sarcomere

actin laments

myosin laments

C.

dark band

myosin laments

actin laments

D.

dark band

actin laments

myosin laments

2210-6007

19

M10/4/BIOLO/HPM/ENG/TZ1/XX+

37. The diagram below shows some stages in the production of monoclonal antibodies. What are stages
X, Y and Z?
Tumour cells

X
Y

Tissue culture
Z

Monoclonal antibodies
isolated for cultivation
[Used with the permission of Access Excellence @ the National Health Museum]

A.

injection of antibody

isolation of B-cell

fusion between B-cell and tumour cell


resulting in plasma cell

B.

injection of antibody

isolation of T-cell

fusion between T-cell and tumour cell


resulting in plasma cell

C.

injection of antigen

isolation of T-cell

fusion between T-cell and tumour cell


resulting in hybridoma cell

D.

injection of antigen

isolation of B-cell

fusion between B-cell and tumour cell


resulting in hybridoma cell

2210-6007

Turn over

20

M10/4/BIOLO/HPM/ENG/TZ1/XX+

38. In the diagram of the nephron below, what structures are indicated by the letters Y and Z?

Z
Y

[Source: adapted from http://ex.susd.org/sjones/SGHL12007 les/image005.jpg]

A.

glomerulus

collecting duct

B.

Bowmans capsule

collecting duct

C.

Bowmans capsule

distal convoluted tubule

D.

glomerulus

distal convoluted tubule

2210-6007

21

M10/4/BIOLO/HPM/ENG/TZ1/XX+

39. What are the roles of the following structures in the production of semen?
Epididymis

Seminal vesicle

A.

production of a uid
containing alkaline
minerals

production of fructose

maturation of sperm

B.

maturation of sperm

production of a uid
containing citric acid

production of fructose

C.

maturation of sperm

production of fructose

production of a uid
containing alkaline
minerals

D.

production of a uid
containing alkaline
minerals

maturation of sperm

production of fructose

40. What is the role of HCG in early pregnancy?


A.

It prevents the degeneration of the corpus luteum.

B.

It initiates the development of the uterus lining.

C.

It inhibits the production of estrogen.

D.

It stimulates the degeneration of the corpus luteum.

2210-6007

Prostate gland

11

M10/4/BIOLO/HPM/ENG/TZ2/XX+

20. Which feature increases the absorption of glucose in the small intestine?

A.

Villi

B.

Lacteal

C.

Cilia

D.

Goblet cells

21. What is a role of the pacemaker or sinoatrial node (SAN)?


A.

To initiate contraction of the ventricle

B.

To pass the excitation through Purkinje bres

C.

To originate excitation in myogenic muscle

D.

To cause the relaxation of the atria

22. Why are antibiotics effective against bacteria?


A.

They can produce specic antibodies.

B.

They can engulf foreign matter.

C.

They can block specic metabolic pathways.

D.

They can act as a vaccine.

2210-6013

Turn over

12

M10/4/BIOLO/HPM/ENG/TZ2/XX+

23. Which of the following features of the alveoli adapt them to gaseous exchange?

I.

Single layer of cells

II.

Film of moisture

III. Dense network of capillaries

A.

I and II only

B.

II only

C.

II and III only

D.

I, II and III

2210-6013

13

M10/4/BIOLO/HPM/ENG/TZ2/XX+

24. The diagram below shows water in the human body.


Key:
ow of water
movement of water into
digestive system

Saliva
1500 ml

Food and
drink
2000 ml

Gastric
secretions
1500 ml

absorption of water from


the digestive system
5000 ml

Intestinal
secretions
2000 ml

Liver (bile)
1000 ml
9000 ml

Pancreas
(pancreatic juices)
1000 ml

Small intestine
Ileocecal valve
1200 ml

Colonic mucus
secretions
200 ml

1400 ml

Colon

Feces
150 ml

Where in the digestive system is the largest volume of water absorbed from?

A.

Colon

B.

Pancreas

C.

Small intestine

D.

Liver

2210-6013

Turn over

18

M10/4/BIOLO/HPM/ENG/TZ2/XX+

34. What kind of inheritance does skin colour represent?


A.

Sex-linked (X-linked)

B.

Multiple alleles

C.

Systemic

D.

Polygenic

35. Which are the possible recombinants in a dihybrid test cross involving the linked genes

A.

B.

C.

D.

JQ
JJ
and
jq
Qq

Jq
Qq
and
Qq
JJ

Jq
jQ
and
jq
jq

Jq
JQ
and
jq
jQ

36. How can active immunity be acquired?


A.

By having the disease

B.

Injection of antibodies

C.

Through colostrum

D.

Via placenta

2210-6013

JQ
?
jq

19

M10/4/BIOLO/HPM/ENG/TZ2/XX+

37. What are fused in the production of monoclonal antibodies?


A.

Tumour cells and T-cells

B.

Tumour cells and B-cells

C.

B-cells and T-cells

D.

Antibodies and antigens

38. The diagram below shows the side view of the arm joint.

Which letter is pointing to the ulna?

A.

B.

C.

D.

39. Which of the following best describes what happens in the glomerulus?

A.

Selective reabsorption of water and molecules by active transport

B.

Ultraltration introduces water and other molecules into the capillaries

C.

Regulation of salt balance leading to the production of urine

D.

High blood pressure forces water and other molecules into the nephron

2210-6013

Turn over

20

M10/4/BIOLO/HPM/ENG/TZ2/XX+

40. Which pair of statements best describes oogenesis and spermatogenesis?


Oogenesis

Spermatogenesis

A.

Four eggs are produced


per mitosis every 28 days

Millions of sperms are


produced per mitosis

B.

Four eggs are produced


per meiosis every 28 days

One sperm is produced per


meiosis

C.

One egg is produced per


mitosis every 28 days

Millions of sperms are


produced per meiosis

D.

One egg is produced per


meiosis every 28 days

Four sperms are produced


per meiosis

2210-6013

N11/4/BIOLO/HPM/ENG/TZ0/XX
27.

most

28.

29.

8811-6001

Turn over

N11/4/BIOLO/HPM/ENG/TZ0/XX
30.

31.

32.

8811-6001

N11/4/BIOLO/HPM/ENG/TZ0/XX
33.

immediately

34.

35.

36.

8811-6001

Turn over

M12/4/BIOLO/HPM/ENG/TZ1/XX
23.

24.

25.

2212-6007

not

Turn over

M12/4/BIOLO/HPM/ENG/TZ1/XX
19.
Atrio-ventricular valve

Semilunar valve

20.

21.

22.

2212-6007

M12/4/BIOLO/HPM/ENG/TZ1/XX
34.

both

35.

36.
Antigens injected into
a child by vaccination

2212-6007

Antibodies crossing the


placenta to the fetus

Antibodies received
by baby from
breastfeeding

Turn over

M12/4/BIOLO/HPM/ENG/TZ1/XX
37.

38.
ADH

39.

2212-6007

Permeability of the
collecting duct to water

M12/4/BIOLO/HPM/ENG/TZ1/XX
40.

2212-6007

M12/4/BIOLO/HPM/ENG/TZ2/XX
18.

19.

20.

21.

2212-6013

M12/4/BIOLO/HPM/ENG/TZ2/XX
22.

23.

2212-6013

Turn over

M12/4/BIOLO/HPM/ENG/TZ2/XX
24.

25.

2212-6013

M12/4/BIOLO/HPM/ENG/TZ2/XX
33.

34.

35.

36.

2212-6013

M12/4/BIOLO/HPM/ENG/TZ2/XX
37.

Cortex

Medulla

2212-6013

Turn over

S-ar putea să vă placă și