Name of Patient

E. F.

Age

24 y.o

Height

52

Diagnosis

G1P1 (1001) PU delivered breech iive birth by 1o LSCTS

Sex

Female

Weight

55 kg

Author

M. M. Olmillo

Website

milkv.co.vu

A/N

youre welcome J

DRUG DATA
Generic name:
Cefuroxime

CLASSIFICATION
Pharmacologic:
Cephalosporin (2nd
gen.)

Trade name:
Ceftin, Zinacef
Patients dose:
500 mg BID
Minimum dose:
750mg every 8
hrs, depending
on the severity
Maximum dose:
1.5 g every 8 hrs,
depending on the
severity

MECHANISM OF
ACTION

Chemical: a secondgeneration
cephalosporin that
binds to bacterial cell
membranes and
inhibits cell wall
synthesis

Therapeutic:
Antibiotic

Route:
PO

General
Indications:
> pharyngitis,
tonsillitis
> bacterial
meningitis
> usual neonatal
dosage
> gynaecologic

Therapeutic:
Bactericidal: inhibits
synthesis of bacterial
cell wall, causing cell
death
Pregnancy Category
Risk: B

Contents:
Cefuroxime
Availability:
Tablets:125, 250,
500 mg
Suspension: 125
mg/5ml,
250mg/5ml
Powder for
injection: 750mg,
1.5g
Injection: 750 mg,
1.5g

INDICATION

Onset:
Rapid
Peak:
Immediate
Duration:
18-24 hr.
Half-life:
1.3 hr

Patients actual
indication:
Cefuroxime is
given to
postpartum
mothers to
prevent them
from postoperational
infections
especially c/s
mothers.

CONTRAINDICATI
ON

Contraindicated with
allergy to cephalosporins
or penicillins
Precaution:
Use cautiously with
renal failure, lactation,
pregnancy
Interactiions:
> drug-drug: increased
nephrotoxicity with
aminoglycosides,
increased bleeding
effects with
anticoagulants
> drug-lab test:
possibility of false
results of urine glycose,
using Benedicts
solution, Fehlings
solution, Clinitest tablets

ADVERSE
EFFECTS

CNS: headaches,
dizziness, lethargy,
paresthesias
GI: nausea,
vomiting, diarrhea,
anorexia, abdominal
pain, flatulence,
pseudomembranou
s colitis,
hepatotoxicity
GU: nephrotoxicity
Hematologic: bone
marrow depression
(decreased WBC,
platelets, Hct)
Hypersensitivity:
ranging from rash to
fever to
anaphylaxis; serum
sickness reaction
Local: pain, abscess
at injection site,
phlebitis,
inflammation at IV
site
Other:
superinfections,
disulfiram-like
reaction with alcohol

NURSING
RESPONSIBILITIE
S

Before:
> check the doctors order
> assess for history: hepatic and
renal impairment, lactation,
pregnancy
> assess for physical cues: skin
status, LFTs, renal function tests,
culture of affected area
> Have Vit. K available in case
hypoprothrombinemia occurs
> culture injection site, and arrange
for sensitivity tests before and during
therapy if expected response is not
seen
> take the pts BP
During:
> administer the right drug
> explain to the patient about the
importance and purpose of the drug
> administer at the right time and
right dosage
> avoid alcohol while taking this drug
and for 3 days after because severe
reactions often occur
> discontinue if hypersensitivity
reaction occurs
After:
> document and record.
> take note of side effects: stomach
upset or diarrhea
> report severe diarrhea, difficulty
breathing and unusual tiredness or
fatigue, pain at injection site
> take patients V/S
> perform bedside care

Source: Nursing
2011 Drug Guide
Lippincott, pg. 260

Source: Nursing 2011

Drug Guide Lippincott,
pg. 260

Source: Nursing 2011

Drug Guide Lippincott,
pg. 260

Source: Nursing
2011 Drug Guide
Lippincott, pg. 260

Source: Nursing 2011 Drug

Guide Lippincott, pg. 260

Source: Nursing 2011

Drug Guide Lippincott,
pg. 260

Source: Nursing 2011 Drug Guide

Lippincott, pg. 260