Name of Patient

F. S.

Age

35 y.o

Height

53

Diagnosis

G3P3 (3003) PU del. ceph. term live birth by 1oLSTCS +

BTL w/ variable deaceration; severe preeclampsia
M. M. Olmillo

Sex

Female

Weight

60 kg

Website

milkv.co.vu

A/N

youre welcome J

Author

DRUG DATA
Generic name:
Ceftriaxone
sodium

CLASSIFICATION
Pharmacologic:
3rd generation
cephalosporin

MECHANISM OF
ACTION

Bactericidal; inhibits
synthesis of bacterial
cell wall, causing cell
death.

Trade name/s:
Rocephin
Patients dose:
20mg OD

Therapeutic:
Antibiotic

Maximum dose:
4g/day

Onset: rapid
Peak: immediate

Minimum dose:
50-75 mg/kg/day

Pregnancy Category
Risk: B

Duration: 15-18 hr
Metabolism: 5-10 hr

Available forms:
Powder for
injection 2 g;
injection 1, 2g

Distribution: crosses
the placenta, enters
breast milk

INDICATIONS

For treatment of:

> Lower
respiratory
infections caused
bystreptococcus
pneumoniae
> acute bacterial
otitis media
> UTIs caused by
E. coli
> Gonorrhea
> intra-abdominal
infections
> PID caused by
N. gonorrhoeae
> skin and skin
structure
infections
> septicaemia
> bone and joint
infections
> meningitis
> Lyme disease

CONTRAINDICATI
ON

Contraindicated with
allergy to cephalosporin
or penecillins
Precaution:
Use cautiously with renal
failure, lactation,
pregnancy

Source: 2011
Lippincotts NDG

Interactions:
> drug-drug: increased
nephrotoxicity with
aminoglycosides;
increased bleeding
effects with
anticoagulants
> drug-lab test:
possibility of false results
on tests of urine glucose
using Benedicts
solution, Clinitest tablets

Source: 2011
Lippincotts NDG

Source: 2011
Lippincotts NDG

GI: nausea,
vomiting, diarrhea,
anorexia,
pseudomembranou
s colitis

Hematologic: bone
marrow depression
decrased WBC
count,decreased
platelets, decreased
Hct
Hypersensitivity:
ranging from rash to
fever to anaphylaxis
Local: pain, abscess
at injection site
Others:
superinfections,
disulfram-like
reaction with alcohol

Patients actual
indications:
> postoperative
prophylaxis for
potentially
contaminated
surgical
procedure (1o
LSTCS + BTL)

Source: 2011
Lippincotts NDG

CNS: headache,
dizziness, lethargy

GU: nephrotoxicity

Excretion: bile, urine

Route:
IVTT

ADVERSE
EFFECTS

Source: 2011
Lippincotts NDG

Source: 2011
Lippincotts NDG

NURSING
RESPONSIBILITIE
S

Before:
> check doctors order
> perform handwashing
> introduce drug to the patient and
educate her about its purpose and
importance
> assess for hepatic and renal
impairment, lactation, pregnancy
> assess skin status, LFTs, renal
function tests, culture of affected
area, sensitivity tests
During:
> administer the right drug at the
right dose
> check the patency of the IV site
and IV line
> have vitamin K ready in case
hypoprothrombinemia occurs
> do not mix ceftriaxone with any
other antimicrobial drug
> discontinue if hypersensitivity
reaction occurs
After:
> educate patient to avoid alcohol
while taking this drug and for 3 days
after because severe reactions often
occur
> monitor ceftriaxone blood levels in
patients with severe renal impairment
and in patients with renal and hepatic
impairment
> report severe diarrhea, difficulty
breathing, unusual tiredness or
fatigue, pain at injection site
> document and record.

Source: 2011 Lippincotts Nursing

Drug Guide