Cm chapter 10

1. The functions of the CSF include all

of the following
except:
A. Removal of metabolic
wastes
B. Producing an ultrafiltrate
of plasma
C. Supplying nutrients to the
CNS
D. Protection of the brain and
spinal cord
2. The CSF flows through the:
A. Choroid plexus B. Pia
mater
C. Arachnoid space
Dura mater

D.

3. Substances present in the CSF are

contolled by the:

B. RBC
D.

8. A web-like pellicle in a refrigerated

CSF specimen is
indicative of:
A. Tubercular meningitis
Multiple sclerosis
C. Primary CNS malignancy
D. Viral meningitis

B.

9. Given the following information,

calculate the CSF
WBC count: cells counted, 80; dilution,
1:10; large
Neubauer squares counted, 10.
B. 80
D. 8000

10. A CSF WBC count is diluted with:

4. The CSF tube labeled 3 is sent to:

B.
D.

5. The CSF tube that should be

refrigerated is:
A. Tube 1
C. Tube 3

A. Immature liver function

degradation
C. A recent hemorrhage
Elevated CSF protein

A. 8
C. 800

A. Arachnoid granulations
B.
Blood-brain barrier
C. Presence of one-way valves D.
Blood-CSF barrier

A. The hematology department

The chemistry dpt
C. The microbiology department
The serology dpt

of the following except:

B. Tube 2
D. Tube 4

6. Place the appropriate letter in front

of the statement
that best describes CSF specimens in
these two conditions:
A. Traumatic tap
B. Intracranial hemorrhage
_____Even distribution of blood in all
tubes
_____Xanthochromic supernatant
_____Concentration of blood in tube 1
is greater
than in tube 3
_____Specimen contains clots
7. The presence of xanthochromia can
be caused by all

A. Distilled water B. Normal saline

C. Acetic acid
D. Methylene blue
11. A total CSF cell count on a clear
fluid should be:
A. Reported as normal
B. Not
reported
C. Diluted with normal saline
D.
Counted undiluted
12. The purpose of adding albumin to
CSF before
cytocentrifugation is to:
A. Increase the cell yield
B. Decrease the cellular distortion
C. Improve the cellular staining
D. Both A and B
13. The primary concern when
pleocytosis of neutrophils
and lymphocytes is found in the CSF
is:
A. Meningitis
malignancy
C. Multiple sclerosis
Hemorrhage

B. CNS
D.

14. Neutrophils with pyknotic nuclei

may be mistaken
for:

21. Cells resembling large and small

lymphocytes with
cleaved nuclei represent:

A. Lymphocytes B. Nucleated RBCs

C. Malignant cells D. Spindle-shaped
cells

A. Lymphoma cells
cells
C. Melanoma cells
Medulloblastoma cells

15. The presence of which of the

following cells is
increased when a CNS shunt
malfunctions?
A. Neutrophils
C. Eosinophils
Lymphocytes

B. Macrophages
D.

16. Macrophages appear in the CSF

following:
A. Hemorrhage B. Repeated spinal
taps
C. Diagnostic procedures D. All of the
above
17. Nucleated RBCs are seen in the
CSF as a result of:
A. Elevated blood RBCs
of anemia
C. Severe hemorrhage
marrow contamination

B. Treatment
D. Bone

18. Following a CNS diagnostic

procedure, which of the
following might be seen in the CSF?
A. Choroidal cells B. Ependymal cells
C. Spindle-shaped cells
D. All of the
above
19. Hemosiderin granules and
hematoidin crystals are
seen in:
A. Lymphocytes B. Macrophages
C. Ependymal cells
D.
Neutrophils
20. Myeloblasts are seen in the CSF:
A. In bacterial infections
B. In conjunction with CNS malignancy
C. Following cerebral hemorrhage
D. As a complication of acute leukemia

B. Choroid
D.

22. The normal value of CSF protein

is:
A. 68 g/dL
B. 1545
g/dL
C. 68 mg/dL
D. 1545 mg/dL
23. CSF can be differentiated from
plasma by
the presence of:
A. Albumin
C. Prealbumin
transferring

B. Globulin
D. Tau

24. In plasma, the second most

prevalent protein is IgG;
in CSF, the second most prevalent
protein is:
A. Transferrin
Prealbumin
C. IgA

B.
D. Ceruloplasmin

25. Elevated CSF protein values can

be caused by all of
the following except:
A. Meningitis
sclerosis
C. Fluid leakage

B. Multiple
D. CNS malignancy

26. The integrity of the blood-brain

barrier is measured
using the:
A. CSF/serum albumin index B.
CSF/serum globulin ratio
C. CSF albumin index
D. CSF
IgG index
27. Given the following results,
calculate the IgG index:
CSF IgG, 50 mg/dL; serum IgG, 2
gm/dL; CSF albumin,
70 mg/dL; serum albumin, 5 gm/dL.
A. 0.6
C. 1.8

B. 6.0
D. 2.8

28. The CSF IgG index calculated in

Study Question 27
is indicative of:
A. Synthesis of IgG in the CNS
B. Damage to the blood-brain barrier
C. Cerebral hemorrhage
D. Lymphoma infiltration
29. The finding of oligoclonal bands in
the CSF and not
in the serum is seen with:
A. Multiple myeloma
malignancy
C. Multiple sclerosis
infections

B. CNS
D. Viral

30. A CSF glucose of 15 mg/dL, WBC

count of 5000, 90%
neutrophils, and protein of 80 mg/dL is
suggestive of:
A. Fungal meningitis
meningitis
C. Tubercular meningitis
meningitis

B. Viral
D. Bacterial

31. A patient with a blood glucose of

120 mg/dL would
have a normal CSF glucose of:
A. 20 mg/dL
C. 80 mg/dL
mg/dL

B. 60 mg/dL
D. 120

32. CSF lactate will be more

consistantly decreased in:
A. Bacterial meningitis
meningitis
C. Fungal meningitis
Tubercular meningitis

B. Viral
D.

33. Measurement of which of the

following can be
replaced by CSF glutamine analysis in
children with
Reye syndrome?
A. Ammonia
C. Glucose
ketoglutarate

B. Lactate
D. _-

34. Prior to performing a Gram stain

on CSF, the specimen
must be:
A. Filtered
B. Warmed
to 37_C
C. Centrifuged
D. Mixed
35. All of the following statements are
true about cryptoccocal meningitis
except:
A. An India Ink preparation is positive
B. A starburst pattern is seen on Gram
stain
C. The WBC count is over 2000
D. A confirmatory immunology test is
available
36. The test of choice to detect
neurosyphilis is the:
A. RPR
B. VDRL
C. FTA
D. FTA-ABS