1.

Human seminal plasma, the fluid part of semen, is produced by contributions from the: i. Urethra ii. Prostate iii.
Seminal vesicle iv. Bulbourethral gland
(A). i and iii
(B). i and iv
(C). i, iii and iv
(D). ii, iii and iv
2. Which one of the following statement is correct?
(A). Spermatogenesis is the formation of sperm cells.
(B). Spermatogenesis occurs in the seminiferous tubules.
(C). Follicle-stimulating hormone (FSh) indirectly stimulates spermatogenesis.
(D). All of these are correct
3. Which one of the following statements is incorrect about menopause?
(A). Generally occurs between the ages of 45 and 55
(B). Causes the cessation of the female reproductive cycle
(C). Anterior pituitary no longer produces FSH and LH
(D). Ovaries slowly reduce their secretion of estrogen
4. Which one of the following statement is correct about sertoli cells also called as nurse cells?
(A). Found in adrenal cortex and secrete adrenaline
(B). Found in ovaries and secrete progesterone
(C). Found in pancreas and secrete cholecystokinin
(D). Found in Seminiferous tubules and provide nutrition of germ cells
5. Which one of the following statements about morula in humans is correct?
(A). It has more cytoplasm and more DNA than an uncleaved zygote
(B). It has almost equal quantity of cytoplasm as an uncleaved zygote but much more DNA
(C). It has far less cytoplasm as well as less DNA than in an uncleaved zygote
(D). It has more or less equal quantity of cytoplasm and DNA as in uncleaved zygote
6. Foetal ejection reflex in human female is induced by
(A). Differentiation of mammary glands
(B). Pressure exerted by amniotic fluid
(C). Release of oxytocin from pituitary
(D). Fully developed foetus and placenta
7. Which one of the following is the most likely root cause why menstruation is not taking place in regularly cycling human female?
(A). Retention of well-developed corpus luteum
(B). Fertilisation of the ovum
(C). Maintenance of the hypertrophical endometrial lining
(D). Maintenance of high concentration of sex-hormones in the blood stream
8. The correct sequence of spermatogenetic stages leading to the formation of sperms in a mature human testis is
(A). Spermatogonia-spermatid-spermatocyte-sperms
(B). Spermatocyte-spermatogonia-spermatid-sperms
(C). Spermatogonia-spermatocyte-spermatid-sperms
(D). Spermatid-spermatocyte-spermatogonia-sperms
9. Correct sequence of embryo development:
(A). Gamete Zygote Morula Blastula Gastrula
(B). Gamete Zygote Blastula Morula Gastrula
(C). Gamete Neurula Gastrula
(D). Gamete Neurula Morula

10. Which one of the following statements is incorrect about menstruation?

(A). The beginning of the cycle of menstruation is called menarche
(B). During normal menstruation about 40 ml blood is lost
(C). The menstrual fluid can easily clot
(D). At menopause in the female, there is especially abrupt increase in gonadotropic hormones
11. The hemoglobin of a human foetus:
(A). Has a higher affinity for oxygen than that of an adult
(B). Has a lower affinity for oxygen than that of the adult
(C). Its affinity for oxygen is the same as that of an adult
(D). Has only two protein subunits instead of four
12. What happens during fertilisation in humans after many sperms reach close to the ovum?
(A). Cells of corona radiata trap all the sperms except one
(B). Only two sperms nearest the ovum penetrate zona pellucid
(C). Secretions of acrosome helps one sperm enter cytoplasm of ovum through zona pellucid
(D). All sperms except the one nearest to the ovum lose their tails
13. Column I contains terms and column II contains definitions. Match them correctly and choose the right answer.
Column I
Column II
A

Parturition

Attachment of zygote to endometrium

Gestation

Release of egg from Graafian follicle

Ovulation

Delivery of baby from uterus

Implantation

Duration between pregnancy and birth

Conception

Formation of zygote by fusion of the egg and sperm

Stoppage of ovulation and menstruation

(A). A = q, B = s, C = p, D = t, E = r
(B). A = s, B = r, C = p, D = t, E = q
(C). A = t, B = p, C = q, D = r, E = s
(D). A = r, B = s, C = q, D = p, E = t
14. The figure given below depicts a diagrammatic sectional view of the female reproductive system of humans.
Which one set of three parts out of I VI have been correctly identified?

(A). Perimetrium, (II) Myometrium, (III) Fallopian tube

(B). Endometrium, (III) Infundibulum, (IV) Fimbriae
(C). Infundibulum, (IV) Fimbriae, (V) Cervix
(D). Oviducal funnel, (V) Uterus, (VI) Cervix
15. Given below is a diagrammatic sketch of a portion of human male reproductive system. Select the correct set of
the names of the parts labelled A, B, C, D.

A
(1)
(2)
(3)
(4)

D
Bulbourethral
Ureter
Seminal vesicle Prostate
gland
Bulbourethral
Ureter
Prostate
Seminal vesicle
gland
Bulbourethral
Vas deferensSeminal vesicle Prostate
gland
Bulbourethral
Vas deferensSeminal vesicle
Prostate
gland

(A). Option (1)

(B). Option (2)
(C). Option (3)
(D). Option (4)

16. The Leydig cells as found in the human body are the secretory source of
(A). Glucagon
(B). Androgens
(C). Progesterone
(D). Intestinal mucus
17. In a normal pregnant woman, the amount of total gonadotropin activity was assessed. The result expected was
(A). High levels of FSH and LH in uterus to stimulate endometrial thickening
(B). High level of circulating HCG to stimulate estrogen and progesterone synthesis
(C). High level of circulating FSH and LH in the uterus to stimulate implantation of the embryo

(D). High level of circulating HCG to stimulate endometrial thickening

18. Signals for parturition originate from
(A). Placenta only
(B). Fully developed foetus only
(C). Both placenta as well as fully developed foetus
(D). Oxytocin released from maternal pituitary
19. Which one of the following statements is false in respect of viability of mammalian sperm?
(A). Viability of sperm is determined by its motility
(B). Sperms must be concentrated in a thick suspension
(C). Sperm is viable for only up to 24 hours
(D). Survival of sperm depends on the pH of the medium and is more active in alkaline medium

20. The endocrine structure and the corresponding hormones are listed in the table below. Match the columns and
select the correct option.
Column I
Column II
(a) Hypothalamus
(p) Relaxin
(b) Anterior Pituitary
(q) Estrogen
(c) Testis
(r) FSH and LH
(d) Ovary
(s) Androgens
(t) Gonadotropin releasing hormone
(A). (a) - (t), (b) - (r), (c) - (s), (d) - (q)
(B). (a) - (t), (b) - (r), (c) - (q), (d) - (s)
(C). (a) - (p), (b) - (q), (c) - (s), (d) - (r)
(D). (a) - (r), (b) - (t), (c) - (s), (d) - (q)

21. Hormones and their functions are listed in the table below. Match the columns and select the correct option.
Column I
Column II
(a) Oxytocin
(p) Stimulates ovulation
(b) Prolactin
(q) Implantation and maintenance of pregnancy
(c) Luteinizing hormone
(r) Lactation after child birth
(d) Progesterone
(s) Uterine contraction during labour
(t) Reabsorption of water by Nephrons
(A). (a) - (s), (b) - (r), (c) - (p), (d) - (q)
(B). (a) - (t), (b) - (p), (c) - (s), (d) - (r)
(C). (a) - (s), (b) - (q), (c) - (r), (d) - (t)
(D). (a)- (t), (b) - (r), (c) - (p), (d) - (s)
22. Male Accessory Glands and their functions are listed in the table below. Match the columns and select the
correct option.
Column I (male Accessory Glands)
Column II (Functions)
(a) Seminal vesicle
(i) Secretes watery alkaline fluid for raising vaginal pH
(b) Prostate gland
(ii) Secretes lubricating mucus
(c) Bulbourethral gland
(iii) Secretes fructose & seminal fluid
(A). (a) - (ii), (b) - (iii), (c) - (i)
(B). (a) - (i), (b) - (ii), (c) - (iii)
(C). (a) - (ii), (b) - (i), (c) - (iii)
(D). (a) - (iii), (b) - (i), (c) - (ii)

23. Parts of the sperm and their descriptions are listed in the table below. Match the columns and select the correct
option.
Column I
Column II
(a) Acrosome
(i) contains mitochondria producing energy for the sperm
(b) Head
(ii) whip-like movements to propel the sperm
(c) Midpiece
(iii) contains the chromosomes
(d) Tail
(iv) contains the enzymes for assisting fertilization
(A). (a) - (i), (b) - (ii), (c) - (iv), (d) - (iii)
(B). (a) - (iv), (b) - (iii), (c) - (i), (d) - (ii)
(C). (a) - (iii), (b) - (i), (c) - (ii), (d) - (iv)
(D). (a) - (ii), (b) - (iv), (c) - (iii), (d) - (i)

24. Which one of the following statements is correct?

(A). FSH and LH occur in both males and females
(B). FSH and LH stimulate the follicle to secrete estrogen.
(C). The ovarian cycle depends on the blood levels of FSH and LH.
(D). All of these are correct.

25. Foramen ovale

(A). Is a shallow depression in the interventricular septum
(B). Is a condition in which the heart valves do not completely close
(C). Is a connection between the pulmonary trunk and the aorta in the fetus
(D). Connects the two atria in the fetal heart

26. Short-lived immunity acquired from mother to foetus across placenta or through mother's milk to the infant is
categorized as:
(A). Cellular immunity
(B). Passive immunity
(C). Active immunity
(D). Innate non-specific immunity

27. The part of Fallopian tube closest to the ovary is

(A). Infundibulum
(B). Isthmus
(C). Ampulla
(D). Cervix
28. About which day in a normal human menstrual cycle does rapid secretion of LH (Popularly called LH-surge)
normally occurs?
(A). 5th day
(B). 11th day
(C). 14th day
(D). 20th day

29. Ovulation in the human female normally takes place during the menstrual cycle
(A). At the end of the proliferative phase
(B). At the beginning of the proliferative phase

(C). Just before the end of the secretory cycle

(D). At the mid secretory phase

30. Which of the following structures are derivatives of the endoderm?

(A). Skin and nerve cord
(B). Alimentary canal and respiratory structures
(C). Muscles and blood
(D). Excretory and reproductive structures
31. ZIFT is
(A). Transfer of mixture of sperms and ova into the fallopian tube
(B). Transfer of embryo into the uterus
(C). Transfer of zygote into the fallopian tube
(D). Transfer of mixture of sperms and ova into the uterus

32. At the time of implantation, the human embryo is called

(A). zygote
(B). blastocyst
(C). embryo
(D). Foetus

33. Sertoli cells are nourishing cells in the testis. They also secrete a hormone. Identify the same.
(A). Inhibin
(B). Gonadotropin
(C). Testosterone
(D). Relaxin

34. The type of connective tissue that is associated with the Umbilical cord is:
(A). Adipose connective tissue
(B). Jelly-like connective tissue
(C). Areolar connective tissue
(D). Reticular connective tissue

35. The chemical substance released by activated spermatozoa that acts on the ground substances of the follicle
cells is known as
(A). Progesterone
(B). Hyaluronidase
(C). Relaxin
(D). Gonadotropin

36. Usually the first movements of the foetus and appearance of hair on its head are usually observed during which
month of pregnancy?
(A). Third month
(B). Fourth month
(C). Fifth month
(D). Sixth month

37. Which of the following are secretions produced by the spermatozoa at the time of fertilization?
(A). Fertilizin and sperm lysine
(B). Anti-fertilizin and sperm lysine
(C). Fertilizin and anti-fertilizin
(D). only sperm lysine

38. Which of the following groups of cells in the male gonad, represent haploid cells?
(A). Primary spermatocytes
(B). Spermatogonial cells
(C). Germinal epithelial cells
(D). Secondary spermatocytes

39. In the human female, menstruation can be deferred by the administration of:
(A). Combination of estrogen and progesterone
(B). Combination of FSH and LH
(C). LH only
(D). FSH only

40. Both corpus luteum and macula lutea are

(A). found in human ovaries
(B). a source of hormones
(C). characterized by a yellow colour
(D). contributory in maintaining pregnancy

41. Which one of the following statement is incorrect?

(A). Scrotum regulates the temperature of the developing sperm within the testes.
(B). Middle piece of a sperm contains many mitochondria to provide energy for movement.
(C). Epididymis and ductus deferens also store sperm.
(D). Sperm contributes cytoplasm and organelles to zygote.

42. In spermatogenesis, reduction division of chromosome occurs during conversion of

(A). Secondary spermatocytes to spermatids
(B). Primary spermatocytes to secondary spermatocytes
(C). Spermatogonia to primary spermatocytes
(D). Spermatids to sperms

43. Match the following :

List I
List II
a. Inguinal canal
1. Network of seminiferous tubules
b. Rete testis
2. Secondary sexual characters
c. Leydig cells
3. Far descending of testis
d. Prepuce
4. Dorsal bundles of muscles
e. Corpora cavernosa
5. Terminal skin of Penis
The correct match is
(A). a 1, b 2, c 3, d 5, e 4
(B). a 3, b 1, c 4, d 2, e 5
(C). a 3, b 1, c 2, d 5, e 4

(D). a 2, b 4, c 3, d 5, e 1

44. Identify the human development stage shown below as well as the related right place of its occurrence in a
normal pregnant woman, and select the right option for the two together.

(A). Late morula Middle part of Fallopian tube

(B). Blastula End part of Fallopian tube
(C). Blastocyst Uterine wall
(D). 8-celled morula Starting point of Fallopian tube

45. Match List I with List II and choose the correct answer.
List I
List II
a. Hypothalamus
1.
Sperm lysins
b. Acrosome
2.
Estrogen
c. Graafian follicle
3.
Relaxin
d. Leydig cells
4.
GnRH
e. Parturition
5.
Testosterone
(A). a 4, b 1, c 2, d 3, e 5
(B). a 2, b 1, c 4, d 3, e 5
(C). a 2, b 1, c 5, d 4, e 3
(D). a 4, b 1, c 2, d 5, e 3
46. Which one of the followings causes the mammary glands to enlarge at puberty?
(A). Testosterone
(B). Progesterone
(C). Estrogen
(D). Oxytocin

47. What is the inner lining of the uterus called?

(A). Cervix
(B). Oviduct
(C). Endometrium
(D). Fimbriae\

48. Where does fertilization usually take place?

(A). Cervix
(B). Vagina
(C). Uterus
(D). Oviduct

49. Which one of the followings regarding 'Estrogen' is correct?

(A). Causes the endometrium to rebuild
(B). Has no effect on the Wolffian duct
(C). Maintains the secondary sexual characteristics in female
(D). All of these

50. The process of sperm production takes place in the ______.

(A). Epididymis
(B). Vas deferens
(C). Prostate glands
(D). Seminiferous tubules

51. Which one of the followings secretes the gonadotropic hormones?

(A). Adrenal
(B). Anterior pituitary
(C). Posterior pituitary
(D). Thyroid

52. The secretory phase in the human menstrual cycle is also called
(A). Luteal phase and lasts for about 6 days
(B). Follicular phase lasting for about 6 days
(C). Luteal phase and lasts for about 13 days
(D). Follicular phase and lasts for about 13 days

53. Vasa efferentia are the ductules leading from

(A). Epididymis to urethra
(B). Testicular lobules to rete testis
(C). Rete testis to vas deferens
(D). Vas deferens to epididymis

54. Which one of the followings is incorrectly matched regarding female reproductive organs?
(A). Ovaries - eggs and sex hormones are produced
(B). Oviducts - serves as the site of fertilization
(C). Uterus - Serves as the birth canal
(D). Cervix - Contains opening to embryo/fetus

55. Which one of the followings is incorrectly matched regarding male reproductive organs?
(A). Testes: Sperm and sex hormones are produced
(B). Epididymis: Ducts where sperm mature
(C). Prostate gland: Contributes fluid to semen
(D). Urethra: Contributes nutrients and mucus-containing fluid to semen

56. Which one of the following events occurs in luteal phase (or secretory phase) of the menstrual cycle?
(A). Follicle-stimulating hormone (FSH) secretion begins

(B). Follicle maturation takes place

(C). Corpus luteum forms
(D). Endometrium breaks down

57. Where do the female gonads (paired ovaries) lie?

(A). Pelvic cavity
(B). Thoracic cavity
(C). Abdominal cavity
(D). Scrotal sacs

58. Which one of the following statements about human sperm is correct?
(A). Acrosome serves no particular function
(B). Acrosome has a conical pointed structure used for piercing and penetrating the egg resulting in fertilization
(C). The sperm lysins in the acrosome dissolve the egg envelope facilitating fertilization
(D). Acrosome serves as a sensory structure leading the sperm towards the ovum

59. The testes in humans are situated outside the abdominal cavity inside a pouch called scrotum. The purpose
served is for
(A). Providing a secondary sexual feature for exhibiting the male sex
(B). Maintaining the scrotal temperature lower than the internal body temperature
(C). Escaping any possible compression by the visceral organs
(D). Providing more space for the growth of epididymis

60. If for some reason, the vasa efferentia in the human reproductive system get blocked, the gametes will not be
transported from
(A). Vagina to uterus
(B). Testes to epididymis
(C). Epididymis to vas deferens
(D). Ovary to uterus
61. 32-celled stage of human embryo is
(A). Smaller than fertilized egg
(B). Same size as fertilized egg
(C). Two times the size of fertilized egg
(D). Four times the size of fertilized egg

62. A cross section at the midpoint of middle piece of human sperm will show
(A). Centriole, mitochondria and 9 + 2 arrangement of microtubules
(B). Centriole and mitochondria
(C). Mitochondria and 9 + 2 arrangement of microtubules
(D). 9 + 2 arrangement of microtubules only

63. A mature sperm has

(A). A pair of flagella
(B). A nucleus, an acrosome and a centriole
(C). A nucleus, an acrosome, a pair of centrioles
(D). A nucleus, an acrosome, a pair of centrioles and a tail

64. A protective layer around testes is

(A). Tunica adventitia
(B). Tunica vasculosa
(C). Tunica media
(D). Tunica albuginea

65. About 60% of the semen is formed by secretion of

(A). Cowpers gland
(B). Seminiferous tubule
(C). Prostate gland
(D). Seminal vesicles

66. Accessory genital gland found only in males is

(A). Cowpers gland
(B). Bartholins gland
(C). Perineal gland
(D). Prostate gland

67. Acrosomal cap is formed from

(A). Ribosomes
(B). Mitochondria
(C). Nucleus
(D). Golgi complex

68. Acrosome is derived from

(A). Nucleus
(B). Golgi apparatus
(C). Mitochondria
(D). Cytoplasm

69. Acrosome reaction in sperm is triggered by

(A). Release of fertilizin
(B). Release of lysins
(C). Capacitation
(D). Influx of Na+ in sperm

70. After few days of delivery, the mammary glands secrete a highly nutritive fluid called
(A). Colostrum
(B). Renin
(C). Serotonin
(D). Secretin

71. After ovulation, Graafian follicle forms

(A). Corpus luteum
(B). Corpus albicans

(C). Corpus artesia

(D). Corpus callosum

72. Amniotic fluid protects the foetus from

(A). Shock
(B). Encystment
(C). Degeneration
(D). Disease

73. An organ not formed from ectoderm is

(A). Middle ear
(B). Optic nerve
(C). Inner ear
(D). Skin

74. Antrum is cavity of

(A). Ovary
(B). Graafian follicle
(C). Blastula
(D). Gastrual

75. Bartholins glands are situated

(A). on the side of head of some amphibians
(B). at the reduced tail end of birds
(C). on either side of vagina in humans
(D). on either side of vas deferens in humans

76. Binary fission does not occur in

(A). Amoeba
(B). Euglena
(C). Plasmodium
(D). Paramecium

77. Brain/CNS develops from

(A). Ectoderm
(B). Mesoderm
(C). Endoderm
(D). Ectoendoderm

78. Budding method of asexual reproduction occurs in

(A). Amoeba
(B). Plasmodium
(C). Paramecium
(D). Hydra

79. Capacitation of sperm occurs in

(A). Vagina
(B). Female genital tract
(C). Vas efferens
(D). Vas deferens

80. Cauda epididymis leads to

(A). Vas efferens
(B). Vas deferens
(C). Ejaculatory duct
(D). Rete testis

81. Cavity of graafian follicle is

(A). Amniotic cavity
(B). Antrum
(C). Liquor folliculi
(D). Discus proligerous

82. Cells of corona radiata remain grouped together by

(A). Pectins
(B). Lipids
(C). Hyaluronidase
(D). Hyaluronic acid

83. Cells of Leydig occur in

(A). Liver
(B). Ovary
(C). Testis
(D). Spleen

84. Cleavage starts after fertilization in

(A). Fallopian tube
(B). Uterus
(C). Vestibule
(D). Clitoris

85. Connective tissue around seminiferous tubules possess endocrine cells called
(A). Leydig cells
(B). Sertoli cells
(C). Primary germ cells
(D). Both (A) and (B)

86. Conversion of spermatids into sperms is

(A). Spermiogenesis
(B). Ppermatogenesis
(C). Gametogenesis
(D). Metamorphosis

87. Corona radia is made up of

(A). zona pellucid around the oocyte
(B). vitelline membrane
(C). follicular cells around the oocyte
(D). stratum functionalis

88. Corpus leteum develops from

(A). Oocyte
(B). Nephrostome
(C). Graafian follicle
(D). none of the above

89. Corpus luteum

(A). Degenerates during pregnancy
(B). Later forms corpus albicans
(C). Remains present throughout pregnancy
(D). Decreases in size during pregnancy

90. Corpus luteum develops under the influence of

(A). Progesterone
(B). Estrogen
(C). FSH
(D). LH

91. Corpus luteum disintegrates due to non-availability of

(A). LTH
(B). FSH
(C). Progesterone
(D). LH

92. Corpus luteum produces

(A). Estrogen
(B). Testosterone
(C). Progesterone
(D). None of the above

93. Corpus luteum secretes hormone

(A). Estrogen
(B). Progesterone
(C). FSH
(D). LH

94. Correct sequence in development is

(A). Fertilization Zygote cleavage Morula Blastula - Gastrula

(B). Fertilization Zygote Blastula Morula Cleavage - Gastrula
(C). Fertilization Cleavage Morula Zygote Blastula Gastrula
(D). Cleavage Zygote Fertilization Morula Blastula Gastrula

95. Correct sequence of hormone secretion from beginning of menstruation is

(A). FSH, progesterone, estrogen
(B). Estrogen, FSH, progesterone
(C). FSH, estrogen progesterone
(D). Estrogen, progesterone, FSH

96. Cryptorchidism is a condition of tests

(A). Unable to descend in scrotal sacs
(B). Unale to produce sperms
(C). Having been surgically removed
(D). Having remained undeveloped

97. Fertilizin is a chemical substance produced from

(A). Mature eggs
(B). Acrosome
(C). Polar bodies
(D). Middle piece of sperm

98. Immediately after ovulation, the mammalian egg is covered by a membrane known as:
(A). Chorion
(B). Zona pellucid
(C). Corona radiate
(D). Vitelline membrane

99. Loss of reproductive capacity in women after age of 45 years is

(A). Menstruation
(B). Ageing
(C). Menopause

(D). Menarche

100.When released from ovary, human egg contains

(A). One Y chromosome
(B). Two X chromosomes
(C). One X chromosome
(D). XY chromosomes