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CH3
NH2
CH3
H3C
H3C
1. GENERAL INFORMATION
IUPAC Name:
1-(2,5-dimethoxy-4-methylphenyl)propan-2-amine
CAS#:
Synonyms:
Source:
Appearance:
Off-white powder
UVmax (nm):
Not Determined
Chemical Formula
Molecular Weight
Base
C12H19NO2
209
Not Determined
HCl
C12H19NO2 . HCl
245
187.6
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2,5-Dimethoxy-4-methylamphetamine
The Drug Enforcement Administration's Special Testing and Research Laboratory
generated this monograph using structurally confirmed reference material.
3. QUALITATIVE DATA
3.1 NUCLEAR MAGNETIC RESONANCE
Sample Preparation: Dilute analyte to ~10 mg/mL in deuterium oxide (D2O) containing TSP for 0 ppm
reference and maleic acid as quantitative internal standard.
Instrument:
Parameters:
10
Maleic acid (ISTD)
9
8
7
6
5
4
3
TSP
2
1
0
11
6 1
7.0
6.5
6.0
5.5
5.0
4.5
4.0
Chemical
3.5(ppm)
3.0
Shift
1.0
5.0
0.5
2.5
0
1
6.95
2.0
1.0
0.25
0.5
0
6
3.82 3.81 3.80 3.79
1
3.675
3.625
1.5
1.0
2.925
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0.5
1.5
7.5
1.5
2.5
0.50
2.0
3
2.200
1.325
1.275
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2,5-Dimethoxy-4-methylamphetamine
The Drug Enforcement Administration's Special Testing and Research Laboratory
generated this monograph using structurally confirmed reference material.
3.2 Gas Chromatography/Mass Spectrometry
Sample Preparation: Dilute analyte ~ 4 mg/mL base extracted into chloroform
Instrument:
Column:
Carrier Gas:
Helium at 1 mL/min
Injector: 280oC
MSD transfer line: 280oC
MS Source: 230 oC
MS Quad: 150oC
Oven program:
1) 100oC initial temperature for 1.0 min
2) Ramp to 300 oC at 12 oC/min
3) Hold final temperature for 7.0 min
Split Ratio = 25:1, 1 L injected
Temperatures:
Injection Parameters:
MS Parameters:
Retention Time:
166
6
Intensity [x 10 ]
44
151
1.0
40
60
100
120
140
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160
180
209
194
176
178
135
122
115
77
79
80
97
103
105
EI+
51
53
63
65
67
39
91
0.5
200
m/z
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2,5-Dimethoxy-4-methylamphetamine
The Drug Enforcement Administration's Special Testing and Research Laboratory
generated this monograph using structurally confirmed reference material.
3.3 INFRARED SPECTROSCOPY (FTIR)
Insrument:
Scan Parameters:
2035
%Transmittance
1200
420 434
440
451
465
540
1300
685
1400
648
1500
833
856
870
1600
750
895
935
1213
1700
Wavenumber (cm-1)
1045
30
20
1500
999
40
1090
50
2000
1173
1522
60
2500
1147
1595
70
3000
1306
1323 1354
1377
1390 1402
1435 1456
1466
1498
1508
%Transmittance
3500
434
540
648
750
1213
20
1045
30
685
833
870
2872
2908
40
1194
1402
1466
1508
50
999
60
1173
1306
1377
1595
2513
2600
2706
3037
70
1100
1000
900
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800
700
Wavenumber (cm-1)
Page 4 of 5
2,5-Dimethoxy-4-methylamphetamine
The Drug Enforcement Administration's Special Testing and Research Laboratory
generated this monograph using structurally confirmed reference material.
4. ADDITIONAL RESOURCES
Forendex
http://forendex.southernforensic.org/index.php/detail/index/167
Wikipedia
http://en.wikipedia.org/wiki/4-methyl-2,5-dimethoxyamphetamine
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