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Abstract
The relationship between childhood abuse and adult mental and physical health
problems is well documented. Over the lifespan of victims of child abuse, social,
psychological and biological consequences of abuse interact in complex ways.
A biopsychosocial model is applied to the experiences of adult victims of child abuse to
make sense of the complex and varied impacts of child abuse. The long-term difficulties
experienced by adult victims of child abuse are discussed in relation to the neurobiological impacts of child abuse on the childs developing brain. The impact of child
abuse on neuro-endocrine functioning and the structure of the brain, in particular on the
amygdala, hippocampus, left hemisphere, and corpus callosum are explored. A number of
implications for social work practice are outlined.
Keywords: Biopsychosocial Model; Child Abuse; Child Neglect; Neuro-biology; Trauma
The association between child abuse and neglect, and adult mental health problems
has been well-established (Briere, 2002, 2004; Briere & Scott, 2006; Draper et al., 2008;
Harper, Stalker, Palmer, & Gadbois, 2008; Palmer, Brown, Rae-Grant, & Loughin,
2001; Spila, Makara, Kozak, & Urbanska, 2008). A number of research studies have
examined the relationship between traumatic experiences in childhood and later
health concerns and have found that a range of problems, including depression,
anxiety disorders, addictions, personality disorders, eating disorders, sexual disorders,
suicidal behaviour, and physical health problems can be, but are not necessarily,
associated with childhood experiences of abuse (Draper et al., 2008; Spila et al.,
2008). The long-term impact of child abuse is far reaching, with some studies
highlighting that the effects of childhood abuse can last a lifetime (Draper et al.,
2008).
Despite these findings, we still hear the saying What doesnt kill you makes you
stronger and Time heals all wounds. This common wisdom implies that traumatic
experiences, once overcome, result in greater levels of psychological, physical, and
AQ1
Correspondence to: Dominiek Coates, Research and Program Manager, Adults Surviving Child Abuse (ASCA),
Kirribilli Neighbourhood Centre, 1618 Fitzroy St, Sydney, New South Wales 2061, Australia. Email:
dcoates@psrc.com.au
Accepted 19 March 2010
ISSN 0312-407X (print)/ISSN 1447-0748 (online) # 2010 Australian Association of Social Workers
DOI: 10.1080/0312407X.2010.508533
emotional wellbeing. The impact of traumatic events on infants and young children is
often minimised in this way. Although trials and tribulations can build character, they
can also cause biological, neurological, and psychological compromise (Cozolino,
2002). It is ironic that greater resilience is often presumed during infancy and
childhood, a time of greatest vulnerability to the effects of trauma (Perry, Pollard,
Blakely, Baker, & Vigilante, 1995). The effects of early and severe trauma are
widespread, devastating, pervasive, and often difficult to treat (Cozolino, 2002, 2008;
Draper et al., 2008; Giarratano, 2004).
We know that our first intimate or loving relationship with our primary caregiver
informs our expectations and patterns of behaviour (Harlow, 1958). Most social
workers are familiar with attachment theory, a theory of personality development
emanating from John Bowlbys work (1969, 1973, 1980, 1988), which highlights the
relationship between patterns of attachment formed in childhood and patterns of
intimate relationships in adulthood. Attachment theory proposes that the negative
core schema determined by first attachment relationships can fundamentally affect an
individuals capacity to establish and sustain significant attachments throughout life.
Attachment theory suggests that early childhood relationships are internalised and
inform an internal working model of the self, others, and relationships and thus,
influence the pattern of relationships and attachment styles in adult life (Alexander &
Anderson, 1994; Carnelley, Pietromonaco, & Jaffe, 1994). Attachment theory posits
that difficulties associated with abuse-related attachment interact with the childs
biopsychosocial development and are mirrored in relationships throughout a childs
life.
Childhood trauma can have a profound impact on the emotional, behavioural,
cognitive, social, and physical functioning of children (Perry et al., 1995), with the
impacts of child abuse continuing into adulthood (Briere, 2002; Draper et al., 2008;
Perry et al., 1995; Van Der Horst, LeRoy, & Van Der Veer, 2008). However, it should
be noted that the extent and nature of the impact of child abuse and neglect varies
from person to person. A number of reviews have estimated that between a third and
half of individuals who have experienced sexual abuse do not experience adult
psychiatric or psychological problems (Fergusson & Mullen, 1999; McGloin &
Widom, 2001). A variety of factors may influence if and how abuse has an impact,
including the gender of the victim and perpetrator, the type and severity of the abuse,
the duration of and time since the abuse, genetic variations, biopsychological factors,
family reactions and background, and perceived social support (Collishaw et al.,
2007; Futa, Nash, Hansen, & Garbin, 2003; McClure, Chavez, Agars, Peacock, &
Matosian, 2007; Ullman, Filipas, Townsend, & Starzynski, 2007). In addition to a
number of variables that moderate the impact of abuse Rutter (2007) stressed the
important role of the of gene-environment interaction in understanding the
heterogeneity in outcome of childhood adversity and the resilience of the child.
To help make sense of the repercussions of child abuse in adulthood, an
understanding of the effects of child abuse and neglect on a childs biopsychosocial
development is necessary. Therefore, the model adopted to understand the pervasive
393
impact of child abuse in the present paper is the biopsychosocial model, which holds
to the idea that illness and health are the result of an interaction between biological,
psychological, and social factors (Alonso, 2004; Suls, 2004). The primary questions
explored are:
.
How does the quality of the attachment relationship with the primary caregiver
impact on a developing childs physiology?
What are the implications in terms of social work practice with adults who have
experienced child abuse?
A review of the relevant research, with a focus on the biological impacts of child
abuse, is used to explore these questions.
Regulating Stress: Impact of Abuse on Neuro-endocrine Systems
Brain development is affected by stress early on in ones life. Early severe stress and
abuse produces a cascade of neurobiological events that have the potential to cause
enduring changes in brain development, with these neurobiological sequelae, in turn,
playing a significant role in the emergence of psychiatric disorders (Teicher, 2002;
Teicher et al., 2003).
Safety and security are considered crucial factors in early brain organisation. A safe
environment with a caring primary caregiver helps moderate the potentially negative
impact stress places on the developing brain (Gunnar, 1998). It is often suggested that
the role of a primary caregiver is to provide the child with environments that are
stimulating, while at the same time being consistently available to help regulate the
childs physiological arousal and ensure the child does not become overwhelmed. In
secure environments, stressed children seek and receive comfort from the primary
caregiver, which regulates their arousal response and enables them to return to
exploratory activity away from the caregiver (Streeck-Fischer & van der Kolk, 2000).
By providing a balance between soothing and stimulation, and helping the child
regulate and moderate his or her physiological arousal, the primary caregiver helps
the child to develop a biological framework for dealing with future stress (Schore,
1994). Children who are not provided with a secure base, and who cannot rely on
their primary caregiver for comfort, become incapable of calming themselves down
when threatened, and struggle to develop a biological framework for regulating stress.
The main biological system involved in regulating stress is the neuro-endocrine
system.
Extensive research into the neuro-biology of stress has established the link between a
history of childhood abuse and neglect, and neuro-endocrine impacts (Hertsgaard,
Gunnar, Erickson, & Nachmias, 1995; Neigh, Gillespie, & Nemeroff, 2009). The neuroendocrine system refers to the system of interaction between the brain, nervous
system, and hormones; with one of its primary roles the regulation of moods,
emotions, and stress response. Any disruption to the neuro-endocrine system affects a
range of basic psychological and physiological functions. Research suggests that many
of the long-term impacts of child abuse result from the chronic neuro-endocrine
395
The hippocampus plays a critical role in the encoding and retrieval of information
(Desgranges, Baron, & Eustache, 1998), and is implicated in the generation of
dissociative states (Mesulam, 1981), anxiety, and panic disorders (Gray, 1983).
A study by Teicher et al. (1993), using a questionnaire designed to test limbic system
dysfunction in adults, found that adult psychiatric outpatients with a history of
childhood physical or sexual abuse had a significantly higher score, indicating limbic
system dysfunction. This study found a 38% increase in limbic abnormalities
following physical abuse, 49% after sexual abuse, and 113% following more than one
type of abuse.
Hippocampal volume has also been found to decrease after exposure to
environments of extreme stress, especially in childhood (Gould & Tanapat, 1999).
Decreased hippocampal volume has been associated with poorer declarative memory,
increasing the risk of developing PTSD-like symptoms, depression, and physical
inflammations (Danese, Pariante, Caspi, Taylor, & Poulton, 2006).
Impact of Child Abuse on the Cerebral Cortex
Studies have found that child abuse and neglect impact on the development of the
cortex, in particular on the left hemisphere and corpus callosum. A study by Ito et al.
(1998) at McLean Hospital found that children with histories of abuse were twice as
likely as nonabused children to have abnormal electroencephalographs (EEGs). In a
group of 115 psychiatric inpatient children, a significant association was shown
between a history of child physical, sexual, or psychological abuse, and EEG
abnormalities in the left side of the frontal and temporal region of the brain.
Furthermore, this study revealed impaired development of the left brain in abused
patients, suggesting increased activity of the right hemisphere than in healthy
individuals. The right hemisphere of abused subjects had developed to the same
degree as the right hemisphere of controls, while the left hemisphere of the abused
subjects lagged substantially behind the left hemisphere of healthy controls. The left
hemisphere is usually dominant in a variety of tasks, and deals with perception and
expression of language and logical analytical thought. The right hemisphere deals
with the perception and expression of emotions, particularly unpleasant emotions
(Ross, Thompson, & Yenkosky, 1997). Similarly, a study by Choi, Jeong, Rohan,
Polcari and Teicher (2009) found that exposure to parental verbal abuse affects the
integrity of left hemisphere pathways involved with processing language, as well as
fiber tracts involved in emotional regulation. This study highlighted the potential
negative effect of ridicule, humiliation, and disdain on brain connectivity.
The corpus callosum has also been found to be affected by child abuse. The two
hemispheres need to interact closely with each other and are connected through the
corpus callosum (Teicher et al., 2004). Early stress exerts a strong effect on the
degree of rightleft hemispheric integration, with a number of studies having found
that the corpus callosum is smaller in abused children than in healthy children
(De Bellis et al., 1999; De Bellis et al., 2002; Teicher et al., 2004; Teicher, Ito, Glod, &
Andersen, 1997). Furthermore, McLean Hospital (2000) found that abused patients
397
shifted the degree of activity between the two hemispheres to a much greater extent
than normal. They theorised that a smaller corpus callosum leads to less integration
of the hemispheres. This can lead to dramatic shifts in mood or personality.
Impact of Child Abuse on Gene Expression
A study by McGowan et al. (2009) has shown that abuse in early childhood can
dramatically alter the way the brain copes with stress in adulthood. The study
examined samples from the hippocampal region of the brain of 36 people
12 suicide victims with a history of childhood abuse, 12 suicide victims without a
history of childhood abuse, and 12 people who had died suddenly of accidental
causes. While studying the hippocampus region of the brain, the team found that a
gene called NR3C1, which influences the brains susceptibility to stress hormones was
less likely to be activated in people who had been abused. Hence, this study found
that childhood abuse or neglect can alter the function of a gene that controls the
brains response to stress. While child abuse and neglect has previously been shown to
affect brain structure, the study is the first to demonstrate a genetic process that
appears to underlie such changes.
Implications for Social Work Practice
It is clear that early patterns of attachment have powerful effects across the lifespan,
and children who experience child abuse adapt to survive in a dangerous world.
Developmental modifications resulting from excessive stress are designed to help the
individual adapt to high levels of lifelong stress. However, these alterations are not
optimal for survival in a more benign environment (Teicher et al., 2003). Considering
the extent of the biopsychosocial impact of child abuse, therapeutic interventions that
are aimed at assisting individuals who have adapted to a dangerous world to survive
in a safe, or at least safer, world may be appropriate. The question of how social
workers can best assist victims of child abuse, whose brains have developed to survive
in a dangerous world, to adapt to life in comparatively safe environments needs to be
posed. Before outlining some recommendations, the plasticity of the brain needs to
be stressed. As outlined in this paper, there is significant evidence that shows that the
brain is plastic and changes in response to the environment. However, the plasticity of
the brain is not restricted to childhood, but continues throughout adult life. Studies
suggest that the adult brain is almost as malleable and plastic as the childs. (See
Doidge, 2007, for a study of brain plasticity). In a similar way to how the childs brain
adapts to survive in an abusive environment, the adult brain can change and adapt to
living in a safe world.
Teach Your Client Arousal Reduction Strategies
To survive in a dangerous world, victims of abuse learn to react instead of respond. In
times of danger, the emotional part of our brain (limbic system) becomes activated
and produces fightflightfreeze hormones to enhance survival before the slower
cortex becomes activated. When under attack, instinctive reactions are more
important in terms of survival than a carefully deliberated response. As discussed,
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