INTERNATIONAL ISLAMIC UNIVERSITY MALAYSIA

COURSE OUTLINE

Kulliyyah

Science

Department

Biotechnology

Program

Bachelor of Biotechnology (Honours)

Name of Course /
Mode

Medical Biotechnology

Course Code

SBT 2253

Name (s) of
Academic staff /
Instructor(s)

Dr. Qabirul Karan Sanusi Abdullah

Department of Biotechnology
Kulliyyah of Science

Rationale for the

inclusion of the
course / module in
the Program

1. The subject provides essential knowledge forming an important component of biological

sciences subjects
2. The subject equips student with theoretical basis for conducting future scientific research
3. The subject exposes student with certain basic skills in handling material or data for
research in biological sciences

Semester and Year

Offered

Semester I

Status

Core Course

Level

Proposed Start Date

Semester I, 2012

Batch of Student to
be Affected

2012

Credit Value / Hours

Pre-requisites (if any)

SBT 2113 Genetic

SBT 1233 Principles of Cell Biology

Co-requisites (if any)

14

120

Credit Hour Assign to the subject

Total SLT/40

Total SLT

Final exam

Preparation for assessment

Formal assessment
42

Continuous assessment

15

Revision

Non face-to-face learning

(eg. : assignment,
module, project)

Practical/tutorial
42

Consultation/PBL/Seminar

Student-centred learning

Independent Learning
Activities

Contact Learning Time

Teacher-centred
Lecture

Total Student
Learning Time (SLT)

The objectives (aims) of the course are to: -

Course Objectives

1.

Expose students to the general knowledge and current issues of biotechnological

application in medical area.

2.

Introduce the techniques or technologies applied in medical biotechnology.

3.

Discuss the importance of biotechnology application in medicine in an effort to benefit

the Ummah.

Upon completion of this course, students should be able to:

Learning Outcomes

1.

Discuss up-to-date basic concepts of human molecular genetics and relating them to a
few well-known human diseases. C4.

2.

Conversant with the application of technology related to the medical biotechnology field
such as DNA finger printing, SNPs, gene therapy technology to treat cancers and a few
other technologies. C4.

3.

Illustrate knowledge of the basic science behind medical biotechnology in perspective.

C4.

4.

Discuss the potential economic, social, ethical and political impact of the burgeoning
field on society. C4, A3, EM2.

5.

Show critical and creative thinking to solve problems related to the medical
biotechnology field through problem-solving based assessments given in the course.
C4, P3, CTPS2, CS3, TS3, LL2, LS2.

Skills and how they are developed and assessed, project and practical experience and
internship
Assessment
Assignment

Quiz

Transferable Skills

Communication
Critical
thinking
/Problem-solving
Creativity/
Innovation
ICT/Information
management
Team-working
Self awareness

Exam

Skill

How skills are developed

Lectures, problem-solving

Searching relevant resources for

assignments
Practical work, group discussion
Practical work, group di

cussion
(In place of instructional strategy)
Teaching-Learning
and assessment
strategy

Course Synopsis

No
1
2

Teaching-Learning
Lectures, Independent learning
Group assignment, Discussion

Assessment
Exam, Quiz
Project report, assignment

This course will update the students with technology of biotechnology in medical areas,
particularly in disease diagnosis and treatments. Generally the main emphasis is on current
issue of medical biotechnology. It equips the students with extra knowledge which is required
in job market. Furthermore, relevant issues on social and legal aspects will be discussed in
details.

Mode of Delivery
Assessment Methods
and Type/Course
Assessment
State weightage of
each type of
assessment.

Lectures, Assignments, etc

LO
1, 2, 3, 4
5
1, 2, 3, 4
1, 2, 3, 4

Method
Quizzes
Group discussion/ assignment
Mid-term examination
Final Examination
TOTAL

%
10
15
30
45
100
Aims
1
2

1. Discuss up-to-date basic concepts of human molecular genetics

and relating them to a few well-known human diseases.
2. Conversant with the application of technology related to the
medical biotechnology field such as DNA finger printing, SNPs,
gene therapy technology to treat cancers and a few other
technologies.
Mapping of the
course / module to
the program aims

3. Illustrate knowledge of the basic science behind medical

biotechnology in perspective.

4. Discuss the potential economic, social, ethical and political

impact of the burgeoning field on society.
5. Show critical and creative thinking to solve problems related to
the medical biotechnology field through problem-solving based
assessments given in the course.

Mapping of course / module to the Program Learning Outcomes

Program Outcomes
Course Learning Outcomes
O1
1.

2.

3.
4.
5.

Discuss up-to-date basic concepts of human

molecular genetics and relating them to a few
well-known human diseases.
Conversant with the application of technology
related to the medical biotechnology field such as
DNA finger printing, SNPs, gene therapy
technology to treat cancers and a few other
technologies.

O4

O5

O6

O7

O8

O9

Discuss the potential economic, social, ethical and

political impact of the burgeoning field on society.

Total

O3

Illustrate knowledge of the basic science behind

medical biotechnology in perspective.

Show critical and creative thinking to solve

problems related to the medical biotechnology
field through problem-solving based assessments
given in the course.

O2

Content outline of the course / module and the SLT per topic
Learning
Hours

Task/Reading

1-2

An Introduction To Medical Biotechnology

Introduction; The role of genetics in medicine; Single-gene defects;
Multifactorial or complex disorders and traits; Chromosomal
mutations; Mitochondrial mutations; The Human Genome Project.

Chapter 1
[1]

3-4

Principles Of Human Molecular Disease

Overview and principles of human disease with emphasis on cancer
and other important disease.

Chapter 5 & 6
[1]

5-6

Gene Manipulation Technology

Principles, techniques and application of recombinant DNA
technology and cloning in medicine; Nucleic acid analysis; Stem
cells technology; Understanding gene function technology; Human
reproductive technology.

Chapter 8 & 9
[3]

Molecular Diagnostics
Amplification techniques; Molecular diagnosis of infectious disease
and inherited disease; Genetic testing.

Chapter 9 & 10
[3]

Weeks

Topics

Biotechnology Perspective on Biopharmaceuticals

Biotechnology
versus
pharmaceutical
biotechnology;
Pharmacogenetics and pharmacogenomics.

Chapter 1 & 2
[2]

9 - 10

Therapeutics Based on Biotechnology

Monoclonal antibody technology; Vaccines technology; Hormones;
Enzymes; Interferons and Cytokines; Haemopoietic growth factors
and coagulation factors.

Chapter 6 11
[2]

11 - 12

Gene Therapy
Somatic and germline gene therapy; Gene replacement and gene
addition; In vivo, ex vivo and in vitro gene therapy; Transgenic
animal models; Vehicles for gene transfer; Gene therapy for genetic
disease; Gene therapy for non-heritable disorders.

13 - 14

Issues in Medical Biotechnology

Current Issues; Risk and Ethics; Islamic Perspective; Islamic EthicsPopulation control, termination of life, prolongation of life, sex preselection, improving the quality of life, fertility problems,
experiments involving human-beings.

Chapter 7
[1]

Chapter 7-14
[4]

Main references supporting the course

The reference lists shall be presented in accordance with APA bibliographic practices and in alphabetical order.
Required
1. Sudbery, P., (2002), Human molecular genetics, 2nd ed. Pearson Education Limited, London.
2. Ho, R. J. Y., & Gibaldi, M., (2003), Biotechnology and biopharmaceuticals: Transforming proteins and genes to
drugs, John Wiley & Sons, Inc., New Jersey.
3. Bourgaize, D., Jewell, T. R., & Buiser, R. G., (2000), Biotechnology: Demystifying the concepts, Addison Wesley
Longman, Canada.
4. Mohsin Ebrahim, A. F., (1993), Biomedical issues: Islamic perspective, A. S. Noordeen, Kuala Lumpur.
Additional references supporting the course

Recommended
1. Kresina, T. F., (2001), An introduction to molecular medicine and gene therapy, Wiley-Liss, Canada.
2. Ross, D. W., (2003), Introduction to molecular medicine, 3rd ed. Springer, North Carolina.
3. Nussbaum, R. L., Mclnnes, R. R., & Willard, H. F., (2001), Thompson & Thompson genetics in medicine, 6th ed.
W. B. Saunders Company, U. S.
4. Brown, S. M., (2003), Essentials of medical genomics, John Wiley & Sons, Canada.

Prepared by:

Checked by:

Approved by:

Dr. Mohamed Tariqur Rahman

Lecturer
Kulliyyah of Science

Dr. Tg. Haziyamin Tengku Abdul Hamid

Head
Department of Biotechnology
Kulliyyah of Science

Prof. Dr. Kamaruzzaman Hj.

Yunus
Dean
Kulliyyah of Science

At the end of the Program, students are able to:

Outcome

Domain

Activities

PO1

Knowledge

To demonstrate the comprehensive understanding of biotechnology

and other the basic sciences that form the core principle
underpinning main areas of biotechnology

PO2

Psychomotor/
Practical/
Technical
Skills

To be able to apply the theoretical knowledge of biotechnology and

obtain the basic laboratory skills relevant to biotechnology

Critical
Thinking &
Scientific
Approach

To analyze, synthesize and integrate the knowledge of

biotechnology and relevant biological science areas

PO4

Communicatio
n Skills

Communicate and demonstrate interpersonal skills

PO5

Social Skills &

Responsibility

Able to disseminate knowledge and information to general public

concerning the importance of biotechnology.

PO3

To recognize the use of basic biotechnology equipment

Able to design (to a limited scale) and be able to conduct basic and
simple guided experiment as the foundation to future research

To seek, adapt and provide solutions to address the challenges and

concerns in biotechnology.
PO6

Life Long
Learning &
Information
Management

Able to manage and use biotechnology information as the foundation

for self development and continuous improvement

PO7

Professionalis
m, values
attitudes,
ethics

Demonstrate an understanding and awareness of basic commercial,

ethical, legal and social issues related to biotechnology

Managerial &
Entrepreneuria
l Skills

Demonstrate an understanding of basic principles and

entrepreneurship in biotechnology

PO8

PO9

Leadership skill

Able to integrate the knowledge of biotechnology with Islamic

perspective for the benefit of the Ummah

Demonstrate leadership qualities and able to work in a team