DRUG ANALYSIS

Drug name

Kalium
durule
Brand
name:
Potassium
Chloride

Indication

Mechanism of action

Dose

Contraindication

Side Effects

To prevent and
treat potassium
deficit secondary
to diuretic or
corticosteroid
therapy. Also
indicated when
potassium is
depleted by
severe vomiting,
diarrhea;
intestinal
drainage,
fistulas, or
malabsorption;
prolonged
diuresis, diabetic
acidosis

Principal intracellular
action; essential for
maintenance of
intracellular
isotonicity,
transmission of nerve
impulses, contraction
of cardiac, skeletal,
and smooth muscles,
maintenance of
normal kidney
function, and for
enzyme activity.
Plays a prominent
role in both
formation and
correction of
imbalances in acid
base metabolism.

1 tab TID

Severe renal
impairment;
severe hemolytic
reactions;
untreated
Addisons
disease; cushing
syndrome; early
postoperative
oliguria (except
during GI
drainage);a
dynamic ileus;
acute
dehydration; heat
cramps,
hyperkalemia,
patients receiving
potassium-sparing
diuretics, digitalis
intoxication with
AV conduction
disturbance

Arrhythmias,
Heart block,
Hypotension,
Cardiac arrest,
Hyperkalemia,
Respiratory
paralysis.
Adverse
effect:
Nausea,
vomiting,
diarrhea,
abdominal
distension.
Pain, mental
confusion,
irritability,
listlessness,
paresthesias
of extremities,
muscle
weakness and
heaviness of
limbs,
difficulty in
swallowing,
flaccid

Nursing
responsibility
Monitor I&O ratio
and pattern in
patients receiving
the parenteral
drug. If oliguria
occurs, stop
infusion promptly
and notify
physician.

paralysis

Drug name

Indicatio
n

Mechanism of action

Dose

Contraindicati
on

Side Effects

Nursing
Responsibility

Serc
Classification:
Antiemetic
And
Antivertigo

Meniere
s
disease,
Menierelike
syndrom
e (with
symptom
s of
vertigo,
tinnitus
and
sensorin
eural
deafness
) and
vertigo
of
peripher
al origin

It has a histamine-like action.

It is readily absorbed from the
gastrointestinal tract. It is
converted to two metabolites
and peak concentrations in
blood of the two metabolites
are achieved within 3 to
5hours. Most of a dose is
excreted in the urine, in the
form of the metabolites, in
about 3 days.
Unlike some other anti-vertigo
drugs, testing with nystagmus
induced by caloric and
rotational stimulation has
demonstrated that betahistine
does not decrease the
vestibular response, as
recorded by
electronystagmography.

1 tab
BID

Previous
hypersensitiv
e reaction to
the drug
components.

Headache
Heartburn,
indigestion
nausea
stomach upset
vomiting
Adverse effect:
Urticaria, pruritus,
mild gastric
complaints, false
heart beat,
Insomnia

Avoid contact of oral

solution or injection
with skin
Raise bed rails,
institute safety
measures, supervise
ambulation