Preparation No.

12
Calcium Hydroxide Topical Solution
Official, External, USP 31

1. Slake CaO for 5 mins.

(place in mortar or evaporating

Formula
Ingredients
CaOH
Water, qs
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PROCEDURE:

OA
3g
1000mL

CA
0.09g
30mL

Slaking
CaO + 5gtts H2O -> Ca(OH)2
56g/mol

74 g/mol

X:56g/n :: 0.09g:74g/n
X= 0.07 g of CaO

dish, sprinkle with 3-5 gtts of

water, cover with watch glass.
Let it stand for 5 mins.)
2. Add 30 mL cold water
3. Agitate for 30 mins in an ice
bath
4. Filter, collect filtrate
5. Transfer in container (liniment
bottle)
6. Add cold water up to the brim
**there should be no bubbles in bottle
because it indicates presence of

STIR FOR 15 mins.

WHY??
--to increase the solubility of CaOH in
water
**avoid too much exposure to air
AVOID BUBBLES??
Hydrogen + O2
we were preventing the formation of
CaCO3 (white precipitate)
FINAL RESULT:
Clear solution, no bubbles inside your
bottle. Add enough cold water up the
brim of the container.

carbon dioxide.
Ca(OH)2 + CO2 CaCO3 (white ppt)
USES:

Astringent
Protective

Calcium hydroxide is less soluble in

hot water than cold so cold purified
water is the solvent.
SYNONYMS:

lime water
Liquor calcis

CONTAINER && STORAGE:

Soln should be stored in well-filled,
tightly stappered containers to deter
the absorption of CO2 & should be
kept in a cool place to maintain an

adequate concentration of dissolved

3. Avoid holding the iodine crystals

solute, white clear solution.

bec it would stain your hands &

Preparation no 13

jewelries.

Strong Iodine Solution

Solubility of 1g of I2 will be dissolved in

Official, external, USP 31

2950 mL H2O ; it is very slightly

soluble.

FORMULA
Ingredients
Iodine
KI
Water, qs

OA
50g
100g
1000mL

CA
1.5g
3g=3mL
30mL

USES:

Antiseptic
Disinfectant

Solubilizing agent

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PROCEDURE
1. Dissolve KI in 2.5 mL of p.H2O
2. Dissolve Iodine crystals in KI
soln
3. Add sufficient amt of H2O to
obtain 15mL.
SYNONYMS:

Lugols solution

METHOD OF PREPN:

Simple solution Method

Potassium Iodide or sodium iodide

-

Used as solubilizing agent for

iodine

PRECAUTION:
1. Do not use stainless spatula bec
iodine is very corrosive &
reactive, use the porcelain
instead.
2. Watch glass should be used in
weighing

Converts iodine to
triiodocomplex form which is
more water soluble

PHYSICAL APPEARANCE:
Like Betadine.

Preparation no 14

It should be stored in a cool place,

Magnesium Citrate Oral Solution

preferably refrigerator. Keep the bottle

Official, Internal, USP 31

on its side so the cork or rubber liner

of the cap is kept moist & swollen,

FORMULA

thereby maintaining the air tight seal

Ingredients
MgCO3
Anhydrous

OA
15 g
27.4 g

CA
2.14 g
3.91 g

between the cap & the bottle.

Citric Acid
Syrup
Talc
Lemon Oil
KHCO3
p.H2O qs

60 mL
5g
0.1 mL
2.5 g
350 mL

8.57 mL
0.71 g
0.01 mL
0.36 g
50mL

colorless to slightly yellow, clear,

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Magnesium Citrate Oral Solution is a

effervescent liquid having a sweet,
acidulous taste, a lemon flavor. It is
commonly referred to as citrate or
ascapate of magnesia.

EXPECTED RESULT: POP!

Flavoring and sweetening agent

Lemon Oil and Syrup

Aluminum Foil
-

Is used to avoid formation of

molds

Talc
-

Dispersing agent for lemon oil

Clarifying agent w/c will remove
impurities

USES:

Saline Cathartic

HEAT

To allow reaction to take place

Prevent the formation of molds

STORAGE:

Cotton for the exchange of gas

PROCEDURES:
***Refer to your notes.

Preparation no 15
Saponated Cresol Solution

Cresol

Official, External, Poison

FORMULA
Ingredients
Cresol
Vegetable

OA
500mL
350mL

CA
15mL
10.5mL

Oil
Potassium

73 g

2.19 g

OH
Alcohol
P.H2O, qs

Poisonous
Immiscible in water(soap to

dissolve)
Responsible for disinfecting
Caustic like phenol, can burn
skin

*wash with alcohol or ethanol if put in

skin
KOH saponifying agent

55mL
1000mL

1.65 mL
30mL

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Ester vegetable oil (fatty acid)

SAPONIFICATION
Conjugation process

**Use hot plate with temperature not

Hydrolysis of ester by an alkaloid

more than 90c

*Upon addition of cresol, it will bcome
Saponification process

clear, yellow solution after stir.

Is complete if the solution is clear;

formation of bubbles, no oil globules
Is incomplete has globules
TO CONFIRM:
**Test mixture using 1mL water + 1
drop of mixture

METHOD OF PREPN

Chemical or Simple