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A healthy, functioning body naturally increases its insulin levels so that its cells can
absorb glucose, a broken down form of sugar from carbohydrates. For those with
Type 1 Diabetes (T1D), the body cannot produce insulin and therefore cannot
regulate the amount of sugar in the blood. Those with T1D then have to regularly
inject themselves with insulin in order to compensate.
A major problem that T1Ds face is insulin shock, which can cause low blood sugar
formally known as hypoglycemia. This occurs when T1Ds inject themselves with too
much insulin, leading to dangerously low sugar levels which are below 70mg/dl
(Fletcher). On average, most T1Ds experience two mild cases of hypoglycemia per
week (Frank & Daneman, 2010). TD1s can be prescribed glucagon needles for
emergency use. However, the complexities of the application can be intimidating
and difficult to teach friends and family. Severe cases of insulin shock can result in
diabetic coma, brain damage, and death (Story, 2014). In fact, 10% of the 270,000
type 1 diabetic patients in Canada die from experiencing insulin shock and failing to
receive immediate medical attention (Cryer, 2012).
2. Who feels the problem / need most acutely? If there is more than 1
segment that feels this problem/ need, which will you target first and
why?
There are three main segments that suffer from hypoglycemia: T1D, reactive
hypoglycemia, and fasting hypoglycemia. Among the three groups, T1Ds constitute
the highest percentage of hypoglycemia incidences. In addition, the effects of low
blood sugar for reactive and fasting hypoglycemia are not as severe as it is for
T1Ds. However, the reactive and fasting hypoglycemia segments are required to
monitor their blood sugar level more often and follow a stricter diet plan.
We have decided to target the T1D in Canada first. There is a large T1D market in
Canada; since the country is ranked third for having the highest prevalence level of
diabetes among individuals aged 20 to 79 ("Institutional Links."). We believe the
adoption rate for this segment may be higher as type 1 diabetics experience low
blood sugars more often (Hamdy, 2015).
3. How is that problem / need currently being addressed by existing
competitors? Why or how is the problem / need underserved?
Novo Nordis and Elli Lily both offer glucagon kits involving one-time needles in a
complex eight-step application process (GlucaGen Hypokit & Glucagon for Injection).
This process requires practice to perfect and can be intimidating for individuals with
little to no medical background. Both companies suggest T1D to have two kits
handy because mistakes can occur when administering the emergency kit.
In addition, those suffering from insulin shock are dependent on the bystanders who
may be overwhelmed by the medical emergency and failed to consider grabbing the
emergency kit in the first place. Since the Nano-patch will reduce the number of
steps to administer, it will simplify the entire process for bystanders ( "Overview.").