PIMS

1. Ladder pattern of DNA electrophoresis is due to action of

Endonucleases
Exonucleases
DNAse
Caspase
2. Both hyperplasia and hypertrophy is found in

Pregnancy uterus
Cardiac muscle in cardiomegaly
Skeletal muscle in athelete
Breast development in puberty

3. Fat necrosis is most commonly seen in:

Omentum
Breast
Retroperitoneal fat
All of the above
4. All of the following vascular changes are observed in acute
inflammation, except?
Vasodilation
Stasis of blood
Increased vascular permeability
Decreased hydrostatic pressure

5. Major basic protein is formed by

Lymphocyte
Basophil
Neutrophil
Eosinophil

6. A biopsy from a muscle reveals encysted forms of Trichinella

spiralis. What type of white blood cell is most likely to be
increased in numbers in the peripheral blood of this individual?
Basophil
Eosinophil
Macrophage
Neutrophil
7. In acute inflammation due to the contraction of endothelial
cell cytoskeleton, which of the following results?
Delayed transient increase in permeability
Early transient increase in permeability
Delayed permanent increase in permeability
Early permanent increase in permeability

8. Complement responsible for activation of bacterial lysis is

C3a
C3b
C5-9
C5
9. All of the following statements are true regarding reversible
cell injury except?
Formation of amorphous densities in the mitochondrial matrix.
Diminished generation of adenosine triphosphate (ATP)
Formation of blebs in the plasma membrane
Detachment of ribosomes from the granular endoplasmic
reticulum
10. Which of the following substances is produced by the
action of lipoxygenase on arachidonic acid, is a potent
chemotactic factor for neutrophils, and causes aggregation
and adhesion of leukocytes?

C5a
PGI2
IL-8
Leukotriene B4
11. Collagen most abundant in Hyaline cartilage

Type
Type
Type
Type

I
II
III
IV

12. Males are more commonly affected than females in(LQ)

Autosomal dominant
Autosomal recessive
X -linked dominant
X - linked recessive
13. Reverse cholesterol transport is mediated by

HDL
VLDL
LDL
Chylomicron
14. Tendon xanthomas are seen in Familial
Familial
Familial
Familial

hyper cholesterolemia
hyperlipidemic
dysbetalipoproteinemia
lipoprotein lipase deficiency

15. In Marfan's syndrome, aortic aneurysm occurs in: (LQ)

Ascending aorta
Descending aorta
Abdominal aorta
Arch of aorta
16. The chances of having an unaffected baby, when both
parents have achondroplasia, are

0%
25%
50%
100%
17. Cells are least radiosensitive in:

S phase
M phase
GI phase
G0 phase
18. All of the following cell types contain the enzyme
telomerase except
Germinal
Somatic
Hemopoietic
Tumour
19. 5HIAA is increased in urine in
Carcinoid syndrome
Pheochromocytoma
Carcinoma bronchus
Paraganglioma
20. Which of the following is the most common fixative used in
electron microscopy?

Glutaraldehyde
Formalin
Picric acid
Absolute Alcohol