Documente Academic
Documente Profesional
Documente Cultură
Key words:
Obesity;
Overweight;
Evidence-based practice;
Prevention;
Intervention;
Infant feeding practices;
Physical activity;
Growth monitoring;
Sleep;
Guidelines
The aim of this paper is to present an overview of the infancy-related guidelines from the Institute of
Medicine ( IOM, 2011) report Early Childhood Obesity Prevention Policies and highlight research
studies that support their implementation in pediatric practice. Findings from recent studies of infant
growth monitoring, feeding, sleep, and physical activity are presented. Research strategies that may
be applied to today's clinical assessments and interventions are specified. Participation by pediatric
nurses in the development of future multi-component interventions to prevent rapid infant weight gain
is recommended.
2014 Elsevier Inc. All rights reserved.
Background
Childhood obesity is a global problem. The World Health
Organization (WHO) estimates that over 40 million children
under 5 years of age are overweight or obese. While once
considered a public health issue primarily for high-income
countries, childhood obesity rates are rising quickly in
middle- and low-income countries, particularly in urban
areas (World Health Organization, 2012). The significance
of this change in child health status throughout the world is
the long term health consequences of obesity, including
cardiovascular morbidities and early development of type
2 diabetes.
International studies provide evidence that excess weight
gain during infancy is a significant risk factor for later
obesity. A population-based study of infants from the United
States (US) found a positive association between rapid
weight gain in the first 4 months of life and overweight status
at 7 years of age (Stettler, Zemel, Kumanyika, & Stallings,
2002). For American children from low-income minority
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Infant Feeding
The IOM's (2011) infancy-related guidelines for the
prevention of childhood obesity call for health care providers
to encourage exclusive breastfeeding in the first 6 months
and continuation of breastfeeding with the introduction of
solid foods during the second half of infancy. Further, the
report underscores the importance of helping parents
recognize and respond to infant hunger and fullness cues.
Examples of hunger cues in early infancy include sucking on
fist, waking and tossing, and opening mouth while feeding to
indicate wanting more. Conversely, infant cues to satiety or
fullness include behaviors such as turning head away, sealing
lips, and decreasing or stopping sucking (USDA, 2013).
To date, the findings from health care research related to
the healthy infant feeding component of the IOM guidelines
are inconsistent. One systematic review of eight international studies of breastfeeding duration and risk for
overweight or obesity in later childhood found that only
half of the studies reported a dose response of breastfeeding
after adjusting for other known risk factors for obesity
(Arenz, Rkerl, Koletzko, & von Kries, 2004). A metaanalysis of the same relationship was conducted using 17
studies from seven countries in Europe and North America
(Harder, Bergmann, Kallischnigg, & Plagemann, 2005).
The findings strongly supported a dose-dependent association between longer breastfeeding duration and reduced
risk for later obesity. However, due to methodological
differences across studies, adjustment for potential confounders could not be calculated. A later study found a
relationship between breastfeeding duration and overweight at age 4 years, but when the researchers controlled
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for other social and environmental risk factors, the
association diminished and was no longer statistically
significant (Procter & Holcomb, 2008).
To further examine whether breastfeeding offers a
protective factor against later obesity, a study based on the
Copenhagen Perinatal Cohort compared the effects of
breastfeeding duration and age of introduction to solid foods
on body mass index through childhood and adulthood. The
researchers found that later introduction of solids (approximately 6 months of age) was protective against later
overweight, but did not find a protective effect for longer
breastfeeding duration (Schack-Nielsen, Srensen, Mortensen, & Michaelsen, 2010). Researchers in Northern Ireland
found that infants who were introduced to solids prior to
4 months of age were heavier at 7 and 14 months than those in
a comparison group who started solids later. Group
differences remained significant after controlling for breastfeeding duration (Sloan, Gildea, Stewart, Sneddon, & Iwaniec,
2007). Further, a study using a nationally representative data
set in the US that examined the relationship between weight at
12 months of age and adherence to clinical practice guidelines
for feeding behaviors found significant associations with
breastfeeding intensity during the second half of infancy and
age of introduction to solid foods (Gaffney, Kitsantas, &
Cheema, 2012).
In addition to monitoring the source of infant caloric
consumption from breastfeeding, formula feeding and solid
food, the IOM guidelines recommend that health care
providers encourage infant feeding behavior that is responsive to hunger and satiety cues. A recent longitudinal study
of infants offers potential insight into the role of sensitivity to
infant feeding cues in preventing obesity. In a comparison of
babies who were fed at breast with those bottle fed (either
human or nonhuman milk), those who were exclusively
bottle fed gained significantly more weight per month
throughout infancy (Li, Fein, & Grummer-Strawn, 2010; Li,
Magada, Fein, & Grummer-Strawn, 2012). This finding led
researchers to conclude that infant weight gain may not only
be associated with type of milk consumed but also the type of
milk delivery. They proposed that the underlying processes
may be that infants fed at breast develop better selfregulation of intake than bottle fed infants and that mothers
who have breastfed their infants may develop improved
sensitivity and responsiveness to infant cues of hunger and
satiety. Support for this explanation comes from studies of
maternal sensitivity that have found lower levels of
responsiveness to satiety cues to be inversely associated
with infant weight gain (Thompson et al., 2009; Worobey,
Lopez, & Hoffman, 2009). However, a limitation of the
study was the underrepresentation of Hispanic mother
infant pairs in the sample. This is particularly important in
light of a recent US population-based study that found
Hispanic children under 2 years of age have a greater
prevalence of high weight-for-length than non-Hispanic
White, or non-Hispanic Black children (14.8%, 8.4%, 8.7%,
respectively; Ogden, Carroll, Kit, & Flegal, 2012).
Infant Sleep
The IOM infancy-related guidelines for obesity prevention call on health care providers to help families achieve
age-appropriate sleep duration for their babies. While most
research about the link between sleep and childhood obesity
has been conducted with older children, two studies have
examined the relationship between sleep duration in infancy
and weight gain. One study of 6 month old infants found that
shorter nighttime sleep duration, as measured by both
actigraph sleep percentages and parental surveys, was
correlated with higher infant weight-for-length ratios. The
significance of this relationship persisted after adjusting for
potential confounders, such as infant gender, birth weight,
and gestational age (Tikotzky et al., 2010). Another study
used multivariate regression analyses to predict the effects of
infant sleep duration (b 12 h/d vs. 12 h/d) on weight status
among preschoolers. The researchers found that infant sleep
less than 12 h/d was associated with higher BMI and
increased odds of overweight at 3 years of age (Taveras,
Rifas-Shiman, Oken, Gunderson, & Gillman, 2008). Replication and extension of these studies with larger and more
diverse samples will add the body of evidence that informs
practice in this area.
Further, the IOM (2011) guidelines call for testing
strategies that address the behavioral factors that lead to
healthy sleep hygiene for infants. Proposed actions include
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