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TheLumataGroup:HyperpolarizedMagneticResonanceLab
reynan.toledo@gmail
WelcometotheLumataresearchgroupwebsite!Wearea
biomedicalphysicsresearchteamintheDepartmentofPhys
icsattheUniversityofTexasatDallas.Ourlab'smain
researchisfocusedonhyperpolarizedmagneticresonan
ce:instrumentation,physics,optimizationmethodsand
biomedicalapplications(specifically,aberrantcellular
metabolismincancer).Hyperpolarization,technically
dynamicnuclearpolarization(DNP),isaphysicstechnique
whereinwecreateahighdegreeofnonBoltzmann
distributionofinsensitivenuclearspinsatlowtemperatureand
highmagneticfieldviamicrowaveirradiationoffreeelectrons.
Ourgoalistogetthehighestenhancednuclearpolarization
possibleforinsensitivenuclearspinssuchas13C,15N,89Y,
107,109Agetc.byoptimizingthephysicalparametersat
cryogenicconditions(closeto1K).Wethenutilizeafast
dissolutiondevicethatconvertsthefrozenhyperpolarized
samplesatcryogenicconditionsintohyperpolarizedliquidsat
physiologicallytolerabletemperatures.Whatthismeansis
thattheNMRandMRIsignalsofreportermolecules
(NMR/MRImolecularprobesthatcandetectpH,metabolism,
andotherimportantbiologicalactivities)areenhancedby
10,000100,000fold!Weaimtoexploreandinvestigate
newhyperpolarizedNMRandMRIbiosensorstoimprove
medicaldiagnostics.Joinus!
PRINCIPALINVESTIGATOR:LLOYDL.LUMATA,PH.D.
AssistantProfessor(June2014present),BiomedicalPhysics,Depar
tmentofPhysics,UniversityofTexasatDallas,Richardson,TX
75080USA.email:lloyd.lumata@utdallas.edu
PostdoctoralFellow(2014),BiomedicalPhysics,AdvancedImagin
gResearchCenter,UniversityofTexasSouthwesternMedicalCente
r,Dallas,TX75390USA
Ph.D.(2008),ExperimentalCondensedMatterPhysics,NationalHig
hMagneticFieldLaboratory,FloridaStateUniversity,Tallahassee,
FL32310USA
B.S.Physics(2002)PhysicsDepartment,WesternMindanaoState
University,Philippines
Reviewer:MagneticResonanceinMedicine,PhysicalChemistryChemicalPhysics,RSCAdvances
Member,InternationalSocietyforMagneticResonanceinMedicine(ISMRM),AmericanPhysical
Society(APS)
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Society(APS)
TheLumataGroup:HyperpolarizedMagneticResonanceLab
POSTDOCTORALFELLOW
ANDHIKAKISWANDHI,PH.D.
PostdoctoralFellow(2015present),DepartmentofPhysics,University
ofTexasatDallas,Richardson,TX
Ph.D.inExperimentalCondensedMatterPhysics(2014),NationalHig
hMagneticFieldLaboratory,FloridaStateUniversity,Tallahassee,FL
B.S.Physics(2007),UniversityofIndonesia,Jakarta,Indonesia
Researchinterest:DNPinstrumentation,condensedmatterphysics,
chemicalphysics
GRADUATESTUDENTS
PETERNIEDBALSKI
Ph.D.Physicsstudent(2013present),UniversityofTexasatDallas,
Richardson,TX
B.S.Physics(2013),summacumlaude,BenedictineCollege,Atchison,
KS
Member,AmericanPhysicalSociety(APS)
Researchinterest:Hyperpolarization,ESR,OverhausereffectDNP
CHRISTOPHERPARISH
Ph.D.Physicsstudent(2012present),UniversityofTexasatDallas,
Richardson,TX
B.S.PhysicsandMathematics(2012),MidwesternStateUniversity,
WichitaFalls,TX
Member,AmericanPhysicalSociety(APS)
Researchinterest:Hyperpolarization,NMR,chemicalphysics
SARAHFERGUSON
Ph.D.Physicsstudent(2014present),UniversityofTexasatDallas,
Richardson,TX
B.S.PhysicsandMathematics(2014),AngeloStateUniversity,Angelo,
TX
Researchinterest:Hyperpolarization/dissolutionDNP
UNDERGRADUATESTUDENTS
ARMINKHAMOSHI
Arminisanincoming4thyearundergraduatestudentatUTDallas
pursuingadualdegreeinphysicsandpuremathematics.Heisarecipient
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TheLumataGroup:HyperpolarizedMagneticResonanceLab
pursuingadualdegreeinphysicsandpuremathematics.Heisarecipient
ofthe20142015UTDUndergraduateResearchGrantAwardandthe
prestigiousGreenfellowshipatUTSouthwesternMedicalCenter.Heis
currentlyworkingonhyperpolarized13CNMRandelectronspin
resonance(ESR)propertiesofDNPfreeradicals.
THANGTRAN
Thangisanincoming4thyearundergraduatePhysicsstudentatUTD
withaminoraChemistry.HeplanstogotogradschoolandgetaPh.Din
Physicsandbecomeaprofessorinthefuture.Heisinterestedin
QuantumPhysicsandBiomedicalinstrumentsfordetecting,imagingand
manipulatingchemicalsandmaterials.
EDUARDOCERVANTES
Eddieiscurrentlyajuniorundergradstudentmajoringinphysics.Heis
interestedinbothmedicineandphysics.Hewouldliketobeinvolvedin
anythingthatbridgesthegapbetweenthesetwofieldsofstudy.Heis
currentlyworkingonEarthfield'sNMRandMRI.
JAYANTHHARKARA
JayisasophomoreundergradstudentinMechanicalEngineering.Heis
currentlydoinganinternshipatRaytheonandwillcontinueworkinginthe
hyperpolarizedNMR/MRIlabthisFall2015.
CANICELEIDANCEL
I'mstudyingbiologybecauseIplantobeapediatricianoneday.Ihopeto
researchdiseasesthataffectchildren,butI'mopentoanytopic,
especiallyifitdealswithbiomedicalresearch.
ALANZANDERS
AlanisasophomoreB.S.PhysicsstudentatUTDallas.Heisinterestedin
workingonNMRspectroscopy.
MICHELLETRAN
IamMichelleTran,afreshmanatUTD.Iamabiochemistrymajor,pre
med.Researchingcancercells,allowsmetogaininsightintoaparticular
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TheLumataGroup:HyperpolarizedMagneticResonanceLab
med.Researchingcancercells,allowsmetogaininsightintoaparticular
healthissuethatisrelevanttotheworldtoday.Learninghowcancercells
behavethroughtheuseofMRIscouldbewaytoimprovehealth
diagnosesandimprovemedicineforthefuture.
DANIELCARLTON
DanielisaB.S.PhysicsstudentatUTDallas.He'sinterestedin
biomedicalapplicationsofdynamicnuclearpolarization.
ARTEMBOLSHAKOV
ArtemisaB.S.PhysicsstudentatUTDallas.Heiscurrentlyworkingona
steppermotorbasedhomebuiltsurfacescanningmachinewithcontrol
codeswritteninPython.
HIGHSCHOOLSTUDENTS
ALUMNI/FORMERMEMBERS
KylieTacker,B.S.Geophysics,LumataLab
AnaghaKrishnan,TexasAcademyofMathematics
member(Fall2014
andScience,HighSchoolUTDNanoexplorer
currentposition:undergraduateresearcheratDr.
(Summer2015)
AnvarZhakidov'slab(UTDallas).
AayushGoyal,TexasAcademyofMathematics
MudrekhGoderya,B.S.PhysicsandComputer
andScience,HighSchoolUTDNanoexplorer
Science,Lumatalabmember(Fall2014)
(Summer2015)
currentposition:Softwaredeveloper,PetroCloud,
Irving,TX
AnishaOommen,PrestonwoodHighSchool,UTD
Nanoexplorer(Summer2015)
RESEARCHFUNDING
U.S.DepartmentofDefense(DoD)ProstateCancer
ResearchProgram(PCRP)
ExplorationHypothesisDevelopmentGrantAward
PrincipalInvestigator:LloydLumata
Hyperpolarized15NMagneticResonanceImagingof
ProstateCancer
Totalfunding:$114,750.00(October2015October2016),Award
No.W81XWH1410048
TheRobertA.WelchFoundationresearchgrantaward
PrincipalInvestigator:LloydLumata
TrackingCancerMetabolisminRealTimeUsing
Hyperpolarized13CMagneticResonance
TotalFunding:$195,000.00(June2015May2018),Grant
NumberAT1877
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TheLumataGroup:HyperpolarizedMagneticResonanceLab
AVAILABLEPOSITIONS
Wearelookingforhighlymotivatedmembers(graduatestudents)forthe
Lumataresearchgroup.Projectsincludethedevelopmentofdynamic
nuclearpolarization(DNP)/hyperpolarizationinstrumentationfor
biomedicalNMRspectroscopyandimaging,optimizationofDNPsignals,
ESRoffreeradicalpolarizingagents(incollaborationwiththeNationalHi
ghMagneticFieldLaboratoryinTallahassee,FL),invitro
hyperpolarizedNMRspectroscopyofcancercells,andinvivo
hyperpolarized15NMRIofprostatecancer(incollaborationwithAdvance
dImagingResearchCenter,UTSouthwesternMedicalCenter).Please
inquirefromthePI(email:lloyd.lumata@utdallas.edu)formoredetails.
UTDallasGraduate
PhysicsProgram
fromAmerican
InstituteofPhysics
(AIP)catalog
aip_utdallasphysics.
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