Q.no.

1: A 35 years old man who is HIV+ve admitted to emergency ward with

fever, headache and fits. A
C.T scan shows multiple hypodense ring enhancement lesions. What is the most
likely diagnosis?
(a) Cryptococal Meningititis
(b) Cerebral Toxoplasmosis
(c) Cerebral Lymphoma
(d) Tuberculoma
(e) All of the above

Q.No.2: Which of the following is least likely cause of pyrexia of unknown origin?
(a) Infective Endocarditis
(b) Tuberculosis
(c) Lymphoma
(d) SLE
(e) Osteoarthritis
Q.No.3: A house officer sustains a needle stick injury, while doing blood sampling
from a patient who is
HIV +. All of the following are true regarding needle stick injury except?
(a) Do not stop the bleeding and wash the wound immediately
(b) She should wait to initiate prophylaxis at least for three months
(c) Initiate prophylaxis with oral anti-retroviral therapy within 48-72 hrs for four
weeks

(d) Reassure the patient that transmission risk of HIV infection with needle stick
injury is only 0.3%
(e) Prophylaxis reduces the risk of HIV infection by 80%
Q.No.4: A 55 years old diabetic patient presents with Right sided facial nerve palsy
and vesicular lesions in external auditory canal of ear. A clinical diagnosis of
RAMSAY HUNT SYNDROME is made. What is the most likely causative organism?
(a) Herpes Simplex Virus
(b) Varicella Zoster Virus
(c)

Cytomegalovirus

(d)

Ebstein bar virus

(e)

Human papilloma virus

Q.No.5: A 75 years old male patient presented with painful vesicular rash followed
by few crusting lesions along the right side of chest, the most common complication
of disease is
(a)

7th nerve palsy

(b)

Aseptic meningitis

(c)

Transverse myelitis

(d)
(e)

Post herpetic neuralgia

Encephalitis

Q.No.6: 28 year old man is admitted to the emergency department with complaint
of dyspnea and fever. 2 days ago he developed itchy vesicular rash after coming in
contact with child who had chicken pox. Examination of chest reveals occasional
coarse crepitations in right middle lobe of chest. What is the most important
intervention?
(a)

Paracetamol

(b)

Prednisolone

(c)

I.V Acyclovir

(d)

Vericella Zoster immunoglobulins

(e)

I.V Clarithromycin

Q.No.7: Regarding the herpes zoster all are true except

(a)

Involves the dermatomal route

(b)

Infection usually crosses the midline of body

(c) Shingles is reactivation of dormant varicella zoster virus in dorsal root of

ganglion
(d)

Chicken pox is caused by infection with varicella zoster virus

(e)

Early therapy with acyclovir is effective

(f) Post herpetic neuralgia requires aggressive therapy with gabapentin or

amyline

Q.No.8: A 30 years old female patient presented with high grade fever, headache
and severe muscle aches. On examination she has wide spread maculopapular rash.
Investigations reveal Hb 17.2 gm%, TLC count
3.4 x10 9/L, platelets 65 x 109/L,
ALT 146 IU/L.
What is the most likely diagnosis?
(a)

Leptospirosis

(b)

Acute hepatitis

(c)

Malaria

(d)

Dengue fever

(e)

Viral encephalitis

Q.No.9: A 60 years old male patient presented with high grade fever, headache,
and severe body aches, epistaxis and gum bleeding. Screening results show
Hb 16 g%, TLC count 4000, Platelet count 65000, ESR 12mm/L, Urea 48 mg/dl,
Creatinine 1.6 mg/dl,
SGPT 101 U/L

What is the most appropriate initial investigation?

(a)

NS1 antigen

(b)

RNA PCR for dengue virus

(c)

IgM and IgG by ELISA

(d)

Monitoring platelets and hematocrit

(e)

D-dimers levels

Q.No.10: A 34 years old male is diagnosed as HIV+. He is currently normal with no

past medical history. AT what point antiretroviral therapy should be initiated.
At the time of diagnosis
(a)

CD4 < 200 x 106 /L

(b)

CD4 < 250 x 106 /L

(c)

CD4 < 300 x 106 /L

(d)

CD4 < 350 x 106 /L

Q.No.11: A 30 year male who is HIV+ refused to take the HAART therapy. When CD 4
count is < 100 cells/mm3, he can develop all of the following HIV associated
diseases except
(a)

Cerebral Toxoplasmosis

(b)

Cryptococcal meningitis

(c)

Non-Hodgkin Lymphoma

(d)

Pulmonary Tuberculosis

(e)

Primary CNS Lymphoma

Q.No.12: A 27 year old male patient presented with fever, malaise,

lymphadenopathy and maculopapular rash. Monospot test is negative. Give history
of high risk sexual behavior, you are asked to exclude an HIV seroconversion illness.
What is most appropriate investigation?
(a)

GP 120 PCR

(b)

CCR5 PCR

(c)

HIV PCR and P24 antigen

(d)

HIV antibodies

(e)

None of the above

Q.No.13: A 34 year old pregnant female presented with uncomplicated falciparum

malaria. Which of the following is most suitable drug to treat this infection?
(a)

Artemether-Lumefentarine

(b)

Doxycycline

(c)

Quinine

(d)

Mefloquine

(e)

Atovaquine+Proguanil

Q.No.14: A 35 years old male presented for advice regarding the prophylaxis of
malaria. He plans to travel to UK next month. All of the following drugs can be used
to prevent malaria except
(a)

Chloroquine

(b)

Doxycycline

(c)

Malarone(Atovaquine+Proguanil)

(d)

Artemether

(e)

Mefloquine

Q.No.15: A 29 years old female patient develops recurrent febrile illness. Following
investigations she was diagnosed to have Non Falciparum Malaria caused by
Plasmodium Vivax. What is the most appropriate treatment?
(a)

Cholorquine followed by primaquine

(b)

Doxycycline

(c)

Sulfadoxine-pyramethamine

(d)

Mefloquine

(e)

Atovaquine+Proguanil (Malarone)