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TEST AP101-2
Urinary System
Questions:
Test Duration:
Reading Time:
INSTRUCTION:
Only Bilingual Dictionaries allowed, NO NOTES. This test consists of one part, 115
multiple choice questions (numbers 1 to 115) to be answered on the computer answer
sheet (115 marks). Write your name and student number in the spaces provided on the
computer answer sheet. Carefully fill in the shapes on the computer-marked answer
sheet under your name and ID number with a 2B pencil. You must only use a 2B pencil
on the computer answer sheet. Please read the instructions on the answer sheet
carefully and follow them precisely. Select the best answer to questions. If you are
unsure of an answer, eliminate the alternatives that you know to be incorrect and select
answer from the remaining alternatives. To indicate your selection, use a 2B pencil to
blacken the corresponding oval on the computer answer sheet, AP101-1. No marks are
deducted for wrong answers. So students are advised to move on quickly without
wasting too much time on one question. - Advanced questions; require further reading
or online research.
An increase in the permeability of the cells of the collecting tubule to water is due
11.
A.
B.
C.
D.
12.
A.
B.
C.
D.
13.
A.
B.
C.
D.
14.
A.
B.
C.
15.
A.
B.
C.
The glomerulus differs from other capillaries in the body in that it:
has a basement membrane
is drained by an efferent arteriole
has a blood pressure much lower than other organ systems
3
17.
A.
B.
C.
D.
18.
A.
B.
C.
D.
19.
A.
B.
C.
D.
20.
A.
B.
C.
D.
21.
Place the following in the correct sequence from the formation of a drop of urine to
its elimination from the body.
a. major calyx
b. minor calyx
c. nephron
d. urethra
e. ureter
f. collecting duct
4
A. b, a, c, f, e, d
B. c, a, b, f, e, d
C. f, c, b, a, e, d
D. c, f, b, a, e, d
E.
22.
Aldosterone:
A. presence increases potassium concentrations in the blood
B. is secreted by the neurohypophysis
C. functions to increase sodium resorption
D. production is greatly influenced by ACTH
F.
G.
23.
The enzyme renin is responsible for the activation of
A. angiotensin
B. adrenaline
C. cortisol
D. erythropoietin
H.
24.
Alcohol acts as a diuretic because it ():
A. increases the rate of glomerular filtration
B. inhibits the release of ADH
C. is not reabsorbed by the tubule cells
D. increases secretion of ADH
I.
25.
The juxtaglomerular apparatus is responsible for:
A. the secretion of drugs
B. the secretion of acids and ammonia
C. regulating the rate of filtrate formation and controlling systemic blood pressure
D. reabsorption of organic molecules, vitamins, and water
J.
26.
While the kidneys process about 180 L of blood-derived fluids daily, the amount
that actually leaves the body is ():
A. 100 L
B. all of the 180 L
C. 50% or 90 L
D. 1% or 1.8 L
K.
27.
Which of the following acts as the trigger/stimulus for the initiation of micturition
(voiding)?
A. the stretching of the bladder wall serves as the trigger
B. the pressure of the fluid in the bladder opens a sphincter and allows the urine to
flow by gravity down the urethra
C. the sympathetic efferents are the predominant system controlling micturition
D. motor neurons control micturition
L.
28.
The function of angiotensin II is to:
A. decrease water absorption
B. constrict arterioles and increase blood pressure
C. decrease the production of aldosterone
D. decrease arterial blood pressure
5
M.
29. The chief force pushing water and solutes out of the blood across the filtration
membrane is:
A. the design and size of the podocytes
B. the size of the pores in the basement membrane of the capillaries
C. glomerular hydrostatic pressure (glomerular blood pressure)
D. the thickness of the capillary endothelium
N.
O.
P.
Q.
30.
Which of the following is not reabsorbed by the proximal convoluted tubule?
A. K+
B. Na+
C. creatinine
D. glucose
R.
31.
Micturition is ():
A. a mechanism for concentrating urine
B. production of urine
C. a sacral reflex
D. secretion of acid
S.
32.
Select the correct statement about the nephrons ():
A. the glomerulus is correctly described as the proximal end of the proximal
convoluted tubule
B. filtration slits are the pores that give fenestrated capillaries their name
C. the parietal layer of the glomerular capsule is simple squamous epithelium
D. podocytes are the branching epithelial cells that line the tubules of the nephron
T.
33.
The mechanism of water reabsorption by the renal tubules is:
A. active transport
B. solvent drag
C. co-transport with sodium ions
D. osmosis via aquaporins
U.
34.
Which of the following substances would you expect to find in the filtrate close to
the glomerulus?
A. glucose
B. platelets
C. red blood cells
D. urea
V.
35.
The area responsible for adjusting the final concentration of the urine is the:
A. proximal convoluted tubule
B. collecting Duct
C. loop of Henle
D. macula densa
W.
36.
Which of the following does not stimulate the release of renin by the kidneys ()?
6
A.
B.
C.
D.
X.
37.
A.
B.
C.
D.
38.
A.
B.
C.
D.
Y.
39.
A.
B.
C.
D.
The structure(s) which convey urine from the nephron to the ureters are the:
urethras
collecting ducts
ureters
distal convoluted tubules
Z.
40.
Which one of the following structures contains blood?
A. glomerulus
B. proximal convoluted tubule
C. loop of Henle
D. Bowmans capsule
AA.
41.
Which of the following incorrectly matched the urinary system feature with its
characteristic?
A. creatinine, a protein metabolite found in skeletal muscles and excreted in urine
B. urea, a detoxified ammonia compound
C. glucose, a small amount normally found in the urine
D. uric acid, a nitrogen waste from RNA metabolism
AB.
42.
Which of the following correctly matched urinary term and its characteristic?
A. renal fascia, prevents infection from other areas spreading to kidney
B. juxtamedullary nephrons, short nephrons that constitute the cortex
C. macula densa cells, specialised chemoreceptors
D. renal pelvis, small cup-shaped structures at the apex of the renal pyramids
AC.
43.
Primary site of glucose and amino acid reabsorption in nephrons is:
A. descending limb
B. ascending limb
C. distal convoluted tubule
D. proximal convoluted tubule
AD.
44.
Which of the following incorrectly matches a hormone and its action on the urinary
system?
A. ADH, regulates water reabsorption at the distal convoluted tubule
7
A.
B.
C.
D.
nitrogenous waste
chloride
protein
sodium
AM.
AN.
AO.
AP.
53.
Which of the following is not true?
A. renal clearance tests are conducted to test the glomerular filtration rate (GFR)
B. the macula densa is a chemoreceptor
C. blood pressure in the glomerulus is higher than in other capillary beds
D. none of above
AQ.
54.
Which of the following statements about the urinary system is incorrect?
A. produces rennin, which helps regulate blood pressure
B. carries out the majority of gluconeogenesis in the body
C. produces erythropoietin, which stimulates red blood cell formation
D. metabolizes vitamin D to its active form
AR.
55.
The _____________ attaches the kidney to the posterior body wall.
A. perirenal fat capsule
B. ureter
C. fibrous capsule
D. renal fascia
AS.
56.
The renal ___________ is continuous with the ureter.
A. medulla
B. glomerulus
C. pelvis
D. cortex
AT.
57.
All of the following are layers of the filtration membrane in the glomerular
membrane, except the:
A. fenestrated endothelium
B. basement membrane
C. visceral membrane
D. renal capsule
AU.
58.
All of the following functions are carried out in the renal tubules, except:
A. reabsorption
B. formation of urine
C. filtration
D. secretion
AV.
59.
The ______________ play a major role in acid-base balance in the collecting ducts
().
A. macula densa
B. intercalated cells
C. mesangial cells
9
D. juxtaglomerular cells
AW.
60.
All of the following would stimulate the release of renin from granular cells, except:
A. hemorrhaging or dehydration
B. reduced stretching of the granular cells
C. inhibition by the macula densa cells
D. stimulation of the granular cells by the sympathetic nervous system
61.
If the efferent arteriole constricts while the afferent arteriole remains unchanged,
the glomerular filtration rate:
A. does not change
B. decreases
C. cannot be determined
D. increases
AX.
62.
Urea transport into the medullary collecting duct is enhanced by ():
A. rennin
B. angiotensin II
C. prostaglandin E2
D. ADH
AY.
63.
Which of the following substances is the largest component of urine by weight after
water?
A. creatinine
B. glucose
C. urea
D. protein
AZ.
64.
Which of the following is not true of urinary system ()?
A. juxtamedullary nephrons account for 15% of the nephrons
B. reabsorption occurs through the tubule wall and into the peritubular capillaries
C. the ascending limb of the loop of Henle is impermeable to sodium chloride and
actively transports water into the surrounding interstitial fluids
D. the juxtaglomerular apparatus contains both osmoreceptors and
mechanoreceptors
BA.
65.
Which of the following is false?
A. the distal tubule is under control of ADH and aldosterone
B. blood is carried to the glomerulus via the efferent arteriole
C. the renal corpuscle is composed of the glomerulus and the glomerular (Bowman's)
capsule
D. the stimulus for renin secretion is a drop in systemic blood pressure
BB.
66.
Which of the following is true?
A. the renal cortex contains the glomeruli
B. the thick smooth-muscle layer of the bladder is called the trigone
C. the kidneys are located in the lower abdominal cavity at the L5 to S3 region
D. the myogenic control mechanism reflects the fact that vascular smooth muscle
tends to contract when stretched
BC.
10
D. a, c, f, e, b, d
g.
80.
Renal tubule consists of three parts except:
A. proximal convoluted tubule
B. collecting duct
C. distal convoluted tubule
D. loop of Henle
h.
81.
Which limb of loop of Henle is close to the renal corpuscle?
A. descending
B. ascending
C. proximal
D. distal
i.
82.
Which of the following incorrectly matches urine formation mechanism and its
major site in kidneys?
A. tubular secretion, at proximal convoluted tubule
B. glomerular filtration, at glomerulus
C. tubular reabsorption, at distal convoluted tubule
D. Both A and C
j.
83.
Which of the factor does not contribute to effective filtration at the glomeruli?
A. large surface area of filtration membrane
B. continuous energy supply from adipose capsule
C. permeability of filtration membrane to water and solutes
D. large diameter of afferent arteriole (compared to efferent arteriole)
k.
84.
Which of the pressure is responsible for filtrate formation ()?
A. blood colloid osmotic pressure
B. glomerular hydrostatic pressure
C. capsular hydrostatic pressure
D. net filtration pressure
l.
85.
Glomerular filtration rate (GFR) is directly proportional to both blood pressure (BP)
and net filtration pressure (NFP). Which of the following is not true?
A. hypertension will increase GFR
B. angiotensin II receptor blockers may increase GFR
C. sweating will decrease GFR
D. the action of noradrenaline will decrease GFR
m.
86.
Which of the following hormone is released when there is a wide fluctuation in
water balance?
A. antidiuretic hormone (ADH)
B. aldosterone
13
C. renin
D. all above
n.
87.
The proteins in collecting ducts that open in response to ADH, allowing water
reabsoprtion are called:
A. glycoprotein
B.
+
+
Na - K
pump
C. aquaporins
D. integral proteins
o.
88.
detects a reduction in concentration of water (or osmolarity in blood), and
then stimulates _______
to release ADH ().
A. midbrain, anterior pituitary gland
B. hypothalamus, neurohypophysis
C. medulla oblongata, adenohypophysis
D. medulla oblongata, posterior pituitary gland
p.
q.
89.
Diuretic drugs are prescribed for many medical conditions. Which of the following
condition would be inappropriate to administrate diuretics?
A. hypertension
B. diabetes
C. edema of congestive heart failure
D. anuria
r.
90.
One of kidneys functions is maintaining homeostatic balance of blood pH. Which of
the following is not strictly one of renal mechanisms involved in this function ()?
A. tubular secretion of
+
H
B. tubular reabsorption of
HC O 3
+
H and tubular reabsorption of
HC O 3
A. polydipsia
B. hyperglycaemia
C. anuria
D. glycosuria
u.
93.
There are two types of diabetes. Both types result when
hormone) is absent or deficient.
A. glucagon
B. insulin
C. glycogen
D. angiotensin II
(a
v.
B. 0.095 ~ 1.0
C. 1.001 ~ 1.035
D. 1.5 ~ 1.75
ab.
99.
A layer of ureter wall which allows propulsion of urine by contraction mechanism
similar to in digestive system is called:
A. adventitia
B. transitional epithelium
C. muscularis
D. mucosa
ac.
100. Any unusual chemical or substance in urine may indicate pathology. Which of the
following substance in urine does not indicate pathology?
A. pus
B. uric acid
C. bile pigments
D. lymphocytes
ad.
101. Which of the following has the highest concentration (or most abundant) in the
urine?
A. urea
B. creatitine
C. water
D. uric acid
ae.
102. Ureters, tubelike organs that furnish transportation channels for urine, have the
wall that composed of three layers. One of three layers, mucosa consists of two tissue;
epithelium and lamina propria (hint: mucosa of ureter wall can be stretched when a
large volume of urine has to be transported to the bladder).
A. transitional
B. stratified
C. simple columnar
D. simple cuboidal
af.
103. Valve-like folds that prevent back flow (i.e., reflux) of urine are found in ():
A. major calyx
B. ureters
C. bladder
D. urethra
ag.
104. A homeostatic imbalance condition results from crystallisation of calcium or
magnesium ions, or uric acid salts in urine that obstruct a ureter and block urine
drainage is called:
A. renal ptosis
16
B. renal calculi
C. pyelitis
D. hydronephrosis
ah.
105. In urinary bladder,
ureter opening(s) and
urethral opening(s)
forms a trigone where many infections persist.
A. two, one
B. one, two
C. three, none
D. none, three
ai.
106. Which of the following allows urinary bladder to store more urine without a
significant rise in internal pressure?
A. longitudinal layer
B. detrusor muscle
C. transitional epithelium
D. circular layer
aj.
107. Which sex is more susceptible to urinary tract infections and why?
A. male, due to longer urethra
B. female, due to longer urethra
C. male, due to shorter urethra
D. female, due to shorter urethra
ak.
108. There are two sphincters in urethra important in controlling urine flow from
bladder. The internal urethral sphincter is formed by
muscle, and it is
sphincter. The external urethral sphincter is formed by
muscle, and it is
sphincter ().
A. longitudinal, voluntary; circular, involuntary
B. skeletal, voluntary; detrusor, involuntary
C. circular, involuntary; longitudinal, voluntary
D. detrusor, involuntary; skeletal, voluntary
al.
109. Which of the following is not true?
A. cysititis is a clitoris inflammation in females
B. pyelitis is renal inflammation
C. urethritis is urethra inflammation
D. dysuria is painful urination
am.
110. The act of emptying urinary or simply known as voiding is called:
A. micturition
B. mastication
C. deglutition
D. emesis
17
an.
111. To urinate, three structures must act simultaneously under parasympathetic
activity. Which of the following is not one of them ()?
A. external urethral orifice (relax)
B. external urethral sphincter (relax)
C. detrusor muscle (contract)
D. internal urethral sphincter (open)
ao.
112. In general, healthy humans have some voluntary control of urination until urine
volume exceeds
ml. After this volume of urine,
promotes urination
regardless your wills. After urination
ml urine remain in the bladder().
A. 200, pontine micturition center, 0
B. 200, simple spinal reflex, 10
C. 400, pontine micturition center, 0
D. 400, simple spinal reflex, 10
ap.
113. Which of the following has two centres that participate in the control of urination?
A. midbrain
B. medulla oblongata
C. pons
D. thalamus
aq.
114. In bladder wall,
are activated when there is 200ml of urine in bladder.
Sensory inputs are sent to
region of spinal cord which results in increased
parasympathetic activity and decreased sympathetic activity ().
A. nociceptors, cranial
B. baroreceptors, sacral
C. chemoreceptors, cranial
D. stretch receptors, sacral
ar.
115. Adrenal
has chromaffin cells which synthesis the
such
as adrenaline and noradrenaline ().
A. cortex, corticosteroids
B. medulla, catecholamines
C. cortex, catecholamines
D. medulla, corticosteroids
as.
at.
18