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TEST AP101-3
Questions:
Test Duration:
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INSTRUCTION:
Only Bilingual Dictionaries allowed, NO NOTES. This test consists of one part, 185
multiple choice questions (numbers 1 to 185) to be answered on the computer answer
sheet (185 marks). Write your name and student number in the spaces provided on the
computer answer sheet. Carefully fill in the shapes on the computer-marked answer
sheet under your name and ID number with a 2B pencil. You must only use a 2B pencil
on the computer answer sheet. Please read the instructions on the answer sheet
carefully and follow them precisely. Select the best answer to questions. If you are
unsure of an answer, eliminate the alternatives that you know to be incorrect and select
answer from the remaining alternatives. To indicate your selection, use a 2B pencil to
blacken the corresponding oval on the computer answer sheet, AP101-1. No marks are
deducted for wrong answers. So students are advised to move on quickly without
wasting too much time on one question. - Advanced questions; require further reading
or online research.
Digestion
1. In addition to storage and mechanical breakdown of food, the stomach:
A. is the first site where chemical digestion of starch takes place
B. is the only place where fats are completely digested
C. is the first site where absorption takes place
D. initiates protein digestion and denatures proteins
2. The chemical and mechanical processes of food breakdown are called:
A. absorption
B. digestion
C. secretion
D. ingestion
3. Parietal cells of the stomach produce:
A. mucin
B. pepsinogen
C. hydrochloric acid
D. rennin
4. Which of the following is not true of oblique layer in the stomach ()?
A. allows pummel the food and hence physical breakdown of bolus
B. allows ram the food into the small intestine
C. is a layer of muscularis externa
D. folds into oblique folds called rugae which increases the surface area
5. The solutes contained in saliva include:
A. only proteases and amylase
B. mucin, lysozyme, electrolytes, salts, and minerals
C. only salts and minerals
D. electrolytes, digestive enzyme, mucin, lysozyme, wastes, and IgA
6. The function of the hepatic portal circulation is to:
A. collect absorbed nutrients for metabolic processing
B. return glucose to the general circulation when blood sugar is low
C. distribute hormones
D. carry toxins to the venous system for disposal through the urinary tract
7. When we ingest large molecules such as lipids, carbohydrates, and proteins, they
must undergo catabolic reactions whereby enzymes split these molecules. This series
of reactions is called:
A. absorption
B. secretion
C. chemical digestion
D. mechanical digestion
8. Which of the following is not true of saliva?
A. moistens food and aids in compacting of the bolus
B. contains enzymes that begin the breakdown of proteins
C. cleanses the mouth
D. dissolves food chemicals so they can be tasted
9. There are three phases of gastric secretion. The cephalic phase occurs:
A. immediately after food enters the stomach, preparing the small intestine for the
influx of a variety of nutrients
2
B. before food enters the stomach and is triggered by aroma, sight, or thought
C. when the meal is excessively high in acids and neutralization is required
D. at the end of a large meal, and the juices secreted are powerful and remain in the
GI tract for a long period of time
10.
A.
B.
C.
D.
11.
A.
B.
C.
D.
12.
Why people experience retching before they vomit ()?
A. because the amount of irritants in the stomach has not reached the threshold
B. because esophageal distension by gastric contents induces peristalsis which
forces contents back to stomach
C. because pressure in esophagus is too high to induce vomiting
D. because stomach is not squeezed strong enough
13.
Short-chain triglycerides found in foods such as butterfat molecules in milk are
split by a specific enzyme in preparation for absorption. Which of the following
enzymes is responsible?
A. lipase
B. pepsin
C. rennin
D. cholecystokinin
14.
You have just eaten a meal high in complex carbohydrates. Which of the following
enzymes will help to digest the meal?
A. trypsin
B. cholecystokinin
C. gastrin
D. amylase
15.
A.
B.
C.
D.
16.
A.
B.
C.
D.
17.
A.
B.
C.
D.
18. The ducts that deliver bile and pancreatic juice from the liver and pancreas,
respectively, unite to form the:
A. pancreatic acini
B. hepatopancreatic ampulla
C. bile canaliculus
D. portal vein
19.
The function of the goblet cells is to:
A. provide protection against invading bacteria and other disease-causing organisms
that enter the digestive tract in food
B. absorb nutrients from digested food and store them for future use
C. secrete buffers in order to keep the pH of the digestive tract close to neutral
D. produce mucus that protects parts of the digestive organs from the effects of
powerful enzymes needed for food digestion
20.
A.
B.
C.
D.
21.
A.
B.
C.
D.
22.
Absorption is one of digestive processes. Venous blood containing absorbed
nutrients enters:
A. Peyers patches
B. pancreas
C. liver
D. gallbladder
23.
The ingestion of a meal high in fat content would cause which of the following to
occur?
A. severe indigestion would occur, caused by the lack of sufficient digestive enzymes
B. bile would be released from the gallbladder to emulsify the fat in the duodenum
C. the acid secretions from the stomach would be sufficient to digest this food
D. this type of food would cause secretion of gastrin to cease, causing digestive
upset
24.
A.
B.
C.
D.
25.
A.
B.
C.
D.
26.
A.
B.
C.
D.
produce
produce
produce
produce
mucin
pepsinogen
amylase
HCl
27.
A.
B.
C.
D.
The pancreas:
secretes pancreatic juice through a duct into the stomach
secretes lipase, nuclease, and amylase
is an immune organ that humans can easily live without
secretes bile
28.
A.
B.
C.
D.
29.
A.
B.
C.
D.
The liver:
sends blood into the hepatic portal vein
produces amylase and regulates metabolism of sugars and fats
produces bile and regulates metabolism of sugars and fats
is retroperitoneal
30.
A.
B.
C.
D.
31.
Which of the following incorrectly matches a digestive system cell with its correct
characteristic?
A. chief, produces an inactive enzyme
B. parietal, makes intrinsic factor
C. Kupffer, phagocytic
D. islet, produces lysozyme
32.
Which of the following correctly matches digestive process with the correct
description?
A. ingestion; chewing, mixing, churning, and segmentation of food
B. absorption; taking food into the digestive system
C. chemical digestion; enzymatic degradation of foodstuffs into simpler molecules
D. defecation; passage of digested materials from the lumen of the GI tract into the
blood or lymph
33.
There are two different types of cells (either exocrine or endocrine) in the
pancreas. Which of the following cells or glands is responsible for secreting
pancreatic juice that is important in chemical digestion?
A. pancreatic islets of Langerhans
B. acinar glands
C. adrenal glands
D. cardiac glands
34.
Which of the following is true ()?
A. rugae are located at the inferior end of the stomach which control stomach
emptying
B. pyloric sphincter lies at superior end and regulates movement of food from the
esophagus
5
36.
A.
B.
C.
D.
37.
its
A.
B.
C.
D.
Which of the following incorrectly matches a structure of the small intestines with
description?
ileum contains the valve that connects to the liver
microvilli are also known as the brush border
villi are fingerlike projections of the mucosa
duodenum contains openings for the bile and pancreatic ducts
38.
A.
B.
C.
D.
39.
In order to prevent self-digestion of the pancreas, activation of pancreatic
proteases occurs in the:
A. duodenum
B. pancreas
C. stomach
D. liver
40.
During deglutition (swallowing), the bolus passes into the stomach from the
oesophagus through the:
A. urethral sphincter
B. oesophageal sphincter
C. gastroesophageal sphincter
D. pyloric sphincter
41.
A.
B.
C.
D.
42.
A.
B.
C.
D.
43.
The propulsive function that occurs in the oesophagus is called:
A. swallowing
6
B. defecation
C. peristalsis
D. segmentation
44.
Which of the following is a characteristic of the large intestine?
A. it is the site for acid neutralization
B. it contains a large number of bacteria
C. is longer than the small intestine
D. it provides no absorptive function
45.
From the esophagus to the anal canal, the walls of every organ of the alimentary
canal are made up of the same four basic layers. Arrange them in order from the
lumen ().
A. mucosa, submucosa, muscularis, and serosa
B. serosa, mucosa, submucosa, and muscularis
C. muscularis, serosa, mucosa, and submucosa
D. submucosa, serosa, muscularis, and mucosa
46.
A.
B.
C.
D.
47.
Which sequence below represents the correct layering of the wall of the GI tract,
starting from the layer next to the lumen ()?
A. muscularis externa, serosa, submucosa, mucosa
B. mucosa, muscularis externa, submucosa, serosa
C. mucosa, submucosa, muscularis externa, serosa
D. serosa, mucosa, muscularis externa, submucosa
48.
Which of the following incorrectly matches a substance involved in organic
molecule digestion with its description ()?
A. sucrase, lactase, and maltase; pancreatic enzymes that act on disaccharides
B. bile; emulsifies fats for digestion
C. trypsin; digests proteins in the small intestines
D. none of the above (all correct)
49.
What would be the effect of stripping the small intestines of their villi?
A. greater absorption of nutrients would occur
B. decreased surface area for absorption, which in turn would cause malnutrition &
weight loss to occur
C. the large intestine would take over as the primary absorptive site
D. a duodenal ulcer
50.
A.
B.
C.
D.
51.
A.
B.
C.
D.
52.
A.
B.
C.
D.
53.
A.
B.
C.
D.
54.
Bile salts in bile are important in lipid digestion because it break fat droplets
apart. This process of breakdown is called:
A. lipolysis
B. hydrolysis
C. emulsification
D. oxidation
55.
A.
B.
C.
D.
56.
Which of the following is not one of structure of small intestine that maximise the
potential of absorption?
A. circular folds
B. microvilli
C. villi
D. rugae
57.
The digestive system in a cadaver is longer than in a living person because, in a
cadaver, there is no:
A. muscle tone
B. digestion taking place
C. food in the tube
D. nervous system influence
58.
Pancreatic islets of Langerhans are
hypoglycaemic hormone called
.
A. exocrine, insulin, glycogen
B. endocrine, insulin, glucagon
C. exocrine, glucagon, insulin
D. endocrine, glucagon, insulin
59.
A.
B.
C.
D.
60.
The movement of large intestine begins when food residues:
A. enter the cecum
B. pass ileocaecal sphincter
8
. The secretory
62.
A.
B.
C.
D.
63.
A.
B.
C.
D.
64.
Bilirubin is the chief bile pigment in bile and it is:
A. a waste product of heme of haemoglobin formed during breakdown of worn-out
erythrocytes
B. metabolism of nucleic acids
C. B-oxidation of lipid metabolism in the liver
D. gluconeogenesis
65.
Secretin & CCK are released in intestinal phase of regulation of gastric activity.
These secretions
exit of chyme from stomach and thereby
the rate of
bolus entering into small intestine, and
the rate of bolus passing through
small intestine. Consequently, this allows the maximal
in the
.
A. slow, slow, slow, absorption of nutrients, small intestine
B. speed up, speed up, speed up, digestion of nutrients, small intestine
C. slow, slow, slow, digestion of indigestible food, large intestine
D. speed up, speed up, speed up, absorption of water, large intestine
66.
Which of the following is a false statement?
A. in addition to gastrin, the stomach produces serotonin and histamine to regulate
smooth muscle contraction and parietal cells' release of HCl, respectively
B. protein digestion begins in the oral cavity under the action of salivary peptidase
C. the pancreas is a retroperitoneal organ
D. the pyloric sphincter regulates passage of chyme from the stomach into the
duodenum
67.
Involuntary swallowing is controlled by swallowing center in
. Motor
outputs are transmitted via cranial nerves, mostly by
nerves to muscles of
pharynx and oropharynx.
A. brain stem, vagus
B. midbrain, accessory
C. brain stem, vagus
D. midbrain, vagus
68.
Mass movement:
9
A.
B.
C.
D.
69.
Which of the following is true?
A. the (vermiform) appendix essentially has no known purpose
B. the hepatopancreatic ampulla is composed of the pancreatic duct and the lesser
hepatic duct
C. the submucosa is in direct contact with food
D. digested fats are absorbed into lymphatic lacteals
70.
A.
B.
C.
D.
71.
In anal canal, there are two sphincters involving defecation reflex.
reflex
causes colon and rectum to contract and
anal sphincter to relax. Whereas
anal sphincter is under voluntary control ().
A. sympathetic, internal, external
B. parasympathetic, external, internal
C. sympathetic, external, internal
D. parasympathetic, internal, external
72.
A.
B.
C.
D.
73.
Which of the following is not true of bile?
A. it is a yellow-green, alkaline solution
B. contains only bile salts, bile pigments, cholesterol, triglycerides, phospholipids
and electrolytes
C. only its bile salts and phospholipids aid the digestive process
D. many substances in bile are excreted in urine
74.
A.
B.
C.
D.
75.
_______ circulation collects nutrient-rich blood from the GI tract and delivers it to
the liver.
A. hepatic portal
B. peritoneal
C. subclavian
D. cardiac
76.
Which of the following is not true of the layer of alimentary canal and its function?
78.
A.
B.
C.
D.
79.
A.
B.
C.
D.
80.
Digestion of carbohydrates and proteins by brush border enzymes occurs within
the ________ of the small intestine.
A. rugae
B. microvilli
C. villi
D. goblet cells
81.
A.
B.
C.
D.
82.
A.
B.
C.
D.
83.
A.
B.
C.
D.
84.
A.
B.
C.
D.
85.
A.
B.
C.
D.
86.
A.
B.
C.
D.
liver
stomach
large intestine
small intestine
Gastric juice is:
pancreatic secretions
stomach secretions
hepatic secretions
all of the above
87.
Biliary calculi are solidified cholesterol and bile salts which causes vague
discomfort, jaundice, and pain in the upper abdomen. This is formed at:
A. gallbladder
B. liver
C. pancreas
D. duodenum
88.
A.
B.
C.
D.
89.
A.
B.
C.
D.
90.
A.
B.
C.
D.
91.
A.
B.
C.
D.
92.
A.
B.
C.
D.
93.
Which of the following is not a true statement?
A. the primary goal of digestive tract regulatory mechanisms is to optimize nutrient
breakdown and absorption
B. a weak gastroesophageal sphincter can result in heartburn
C. most digestion occurs in the small intestine
D. constipation results when food passes too quickly through the small intestine
12
94.
A person who does not consume
from diet.
A. protein
B. fat
C. carbohydrate
D. calcium
95.
The normal range of pH in the stomach is
due to the presence of
.
A. 10.5~12.5, acidity, bicarbonate
B. 3.5~5.5, alkalinity, HCl
C. 8.5~10.5, alkalinity, bicarbonate
D. 1.5~3.5, acidity, HCl
and this
is
96.
Which of the following tunics of digestive tract secretes fluid that lubricates the
mobile digestive organs?
A. serosa
B. muscularis externa
C. submucosa
D. mucosa
97.
A.
B.
C.
D.
98.
Which of the following is/are extrinsic autonomic nerves involved in regulating
digestive processes?
A. sympathetic and parasympathetic
B. parasympathetic only
C. sympathetic only
D. enteric nervous plexus
99.
When mucosa of alimentary canal is penetrated, there is a relatively high risk of
microbial infections because all surfaces of GITs are exposed to the external
environment. In oral cavity, which of the following is produced in response to a tissue
(mucosa) injury?
A. IgA
B. lymphocytes
C. defensins
D. saliva
100. In which of the following chemical digestion does not involve brush border
enzymes?
A. protein digestion
B. lipid digestion
C. carbohydrate digestion
D. none of the above
101. The thick stratified squamous epithelium of the oral cavity provides protection
against abrasion. This epithelisum is:
A. keratinised
B. melanised
13
103. Throughout the digestive tract, food can be compacted and partially digested.
Which of the following correctly matches name of food mass along a digestive
passage and a location of its formation (start from food)?
A. chyme (esophagus), bolus (stomach), faeces (large intestine)
B. bolus (mouth), chyme (esophagus), faeces (small intestine)
C. chyme (esophagus), bolus (small intestine), faeces (rectum)
D. bolus (mouth), chyme (stomach), faeces (large intestine)
104.
A.
B.
C.
D.
105. Although stomach is corrosively acidic, it is not normally damaged by its acidity
because it produces:
A. pepsinogen
B. intrinsic factor
C. mucosal barrier
D. serotonin
106. Excessive emesis can have negative effects on health. Which of the following is
not one of them?
A. damaged mucosa of buccal cavity
B. dehydration
C. metabolic acidosis
D. disturbances in electrolyte balances
107.
A.
B.
C.
D.
108.
A.
B.
C.
D.
110.
A soft, retroperitoneal gland which produces a variety enzymes that break
down all categories of foodstuffs, is
and it delivers enzymes to
for chemical digestion.
A. liver, hepatopancreatic ampulla
B. pancreas, duodenum
C. liver, jejunum
D. pancreas, pancreatic duct
112.
A.
B.
C.
D.
113.
A.
B.
C.
D.
The molecule that serves as the major source of readily available body fuel is:
glucose
fat
acetyl CoA
cellulose
117. It is important to ensure that your diet is adequately rich in vitamins because:
A. all vitamins are water-soluble and pass out of the body too quickly to ensure
utilization
B. most vitamins are coenzymes needed to help the body utilize essential nutrients
C. very few foods contain vitamins
D. all of the above
118. Anabolism includes reactions in which:
15
A.
B.
C.
D.
119.
A.
B.
C.
D.
120.
A.
B.
C.
D.
121. Which of the following incorrectly matches an events of metabolism with the
process occurring.
A. gluconeogenesis; production of glucose from a noncarbohydrate source
B. lipogenesis; triglyceride synthesis
C. glycogenesis; polymerization of glucose
D. transamination; N
H3
synthesis
122. The process of breaking triglycerides down into glycerol and fatty acids is known
as:
A. lipolysis
B. fat utilization
C. gluconeogenesis
D. lypogenesis
123.
A.
B.
C.
D.
124.
A.
B.
C.
D.
125.
A.
B.
C.
D.
Which of the following is the amount of energy the body needs to maintain life?
BMI
MR
TMR
BMR
126.
A.
B.
C.
D.
16
127.
______ is considered "good" cholesterol; high blood levels of this cholesterol
are thought to be beneficial. For example, it prevents atherosclerosis and reduces
the risk of heart attack.
A. HDLs (high density lipoproteins)
B. LDLs (low density lipoproteins)
C. chylomicrons
D. VLDLs (very low density lipoproteins)
128. Cholesterol, while it is not an energy molecule, has importance in the body
because:
A. it helps provide essential nutrients to the brain and lungs
B. it is a stabilizing component of the plasma membranes and is the parent molecule
of steroid hormones
C. it helps mobilize fats during periods of starvation
D. it enters the glycolytic pathway without being altered
129.
A.
B.
C.
D.
130.
A.
B.
C.
D.
131.
A.
B.
C.
D.
132.
A.
B.
C.
C. amino acids
D. glycogen
135.
A.
B.
C.
D.
136.
A.
B.
C.
D.
Among the conditions required for measuring the basal metabolic rate is:
being in an absorptive state
keeping the room temperature between 20 and 25 degrees C
remaining in an upright position
sleeping
137.
A.
B.
C.
D.
138.
A.
B.
C.
D.
The hormone responsible for setting the basal metabolic rate is:
insulin
thyroxine
melatonin
glucagon
139.
A.
B.
C.
D.
140.
A.
B.
C.
D.
141. The amount of ________ produced is probably the most important factor in
determining BMR.
A. prolactin
B. thyroxine
C. norepinephrine
D. ADH
142.
A.
B.
C.
A.
B.
C.
D.
triglyceride
cholesterol
protein
glycerol
147.
A.
B.
C.
D.
148. Which of the following incorrectly match a vitamin with its function?
A. Vitamin A; required for synthesis of photoreceptor pigments in vision; integrity of
skin, mucosae, and normal bone; and tooth development
B. Vitamin K; enhances absorption of calcium; works in conjunction with hormones
regulating calcium blood levels
C. Vitamin D; essential for formation of clotting proteins; intermediate in electron
transport; participates in oxidative phosphorylation
D. both B and C
149. In the case of a person who consumes a normal, balanced diet, proteins are
essential to the body for all of the following except:
A. production of energy
B. production of some hormones
C. production of enzymes, clotting factors, and antibodies
D. formation of functional molecules like hemoglobin and cytochromes
150. Which of the following is not true?
A. calcium is a mineral
B. the major function of HDL is to transport excess cholesterol from peripheral
tissues to the liver
C. gluconeogenesis occurs during cell respiration in the mitochondria
D. before lipids can be metabolized, the fatty acids must undergo beta oxidation to
be converted into two-carbon acetic acid fragments
151.
A.
B.
C.
153.
A.
B.
C.
D.
154.
A.
B.
C.
D.
155. Small intestine receives substances from liver and pancreas for chemical
digestion. Which of the following is not one of these?
A. Vitamin B12
B. bile
C. digestive enzymes except brush border enzymes
D. bicarbonate ions
156. Amino acid rich sources such as ______ are important as they are a primary source
of ______, which is required for_______.
A. meat, glucose, fat production
B. fish, protein, enzyme production
C. pasta, glucose, ATP production
D. cheese, fat, ATP production
157. Which of the following is a micronutrient (that is, a nutrient required in minute
amounts), not a major nutrient?
A. water
B. lipids
C. minerals
D. proteins
158.
A.
B.
C.
D.
Insulin:
is abundant in the blood in the starved state
stimulates glycolysis in liver and muscle
stimulates glycogenesis in liver and muscle tissues
is used to produce ATP in cells
159.
A.
B.
C.
D.
160. Which of the choices below is not a fate of carbohydrate taken into the body?
A. ATP production
20
B. lipogenesis
C. conversion to a nucleic acid
D. glycogenesis
161. The molecule that serves as the major source of readily available body fuel in the
fed state is:
A. fat
B. acetyl CoA
C. glucose
D. cellulose
162.
A.
B.
C.
D.
163.
A.
B.
C.
D.
164.
A.
B.
C.
D.
165.
A.
B.
C.
D.
166.
A.
B.
C.
D.
167.
A.
B.
C.
D.
168. When ketone bodies are present in the blood and urine in large amounts, it
usually indicates increased metabolism of:
A. proteins
B. fats
C. glucose
D. lactic acid
169.
A.
B.
C.
D.
What is the preferred use order of energy sources for the body?
glycogen, blood glucose, protein, fat
blood glucose, glucagon, fat, protein
blood glucose, glycogen, fat, protein
the body has no preference for which energy sources to use
21
170.
Most vitamins:
A. have only one function in the body
B. function as coenzymes in the body
C. are metabolized to make ATP
D. are used as building blocks for the body
171.
A.
B.
C.
D.
172.
A.
B.
C.
D.
173.
A.
B.
C.
D.
The hormone that controls essentially all events of the absorptive state is:
thyroxine
ADH
insulin
glucagon
22
174.
The role of _____________ is to transport excessive cholesterol from
peripheral tissue to the liver, where it is broken down and becomes part of bile.
A. high-density lipoproteins (HDLs)
B. very-low-density lipoproteins (VLDLs)
C. low-density lipoproteins (LDLs)
D. Chylomicrons
175.
A.
B.
C.
D.
176. ___________ acts to suppress appetite by inhibiting _____, which is the mostpowerful known appetite stimulant.
A. leptin; neuropeptide Y
B. growth hormone; lipase
C. insulin; glucagon
D. serotonin; adrenaline
177.
A.
B.
C.
D.
178.
A.
B.
C.
D.
179. The ability to convert one type of molecule to another is truly remarkable in the
body, specially:
A. pancreas
B. skeletal muscle
C. adipose tissue
D. liver
180.
A.
B.
C.
D.
181.
A.
B.
C.
D.
182.
A.
B.
C.
Which of the following organ does not prefer fatty acids as an energy fuel?
liver
cardiac muscle
resting skeletal muscles
23
D. brain
183. In the absorptive state, the main thrust is
. In the post-absorptive state, the main thrust is
.
A. catabolism, glucagon; anabolism, insulin
B. anabolism, insulin; catabolism, glycogen
C. hydrolysis, glucagon; synthesis, insulin
D. anabolism, insulin; catabolism, glucagon
184.
A.
B.
C.
D.
Ingested
are absorbed via lymph.
monosaccharides
amino acids
fats
nucleic acids
24