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Documente Cultură
Chilomastix mesnili
Entamoeba coli
Entamoeba histolytica
Endolimax nana
Giardia lamblia
Iodamoeba butschlii
Leishmania donovani
Balantadiasis
Non pathogenic
Non pathogenic
Amoebiasis
Non pathogenic
Giardiasis
Non pathogenic
Visceral Leshmaniasis
Cyst
Cyst
Mature cyst
Cyst
Cyst
Cyst
Cyst
Promastigote
ATRIAL FLAGELLATES
- Lower forms of parasite
- Completely unicellular
- Asexual reproduction Binary fission
- Non pathogenic
o Chilomastix mesnili
- Pathogenic
o Giardia lamblia
Metronidazole
INGESTION
Metronidazole
Stibogluconate Na
TROPHOZOITE
- DIAGNOSTIC STAGE
- Seen in WATERY STOOL
- Has 8 FLAGELLA
- With a pair of nuclei
- FALLING LEAF OTILITY
- PEAR SHAPED
- BINARY FISSION
CYST
- INFECTIVE STAGE
- With CONDENSED FLAGELLA
(cannot be seen, folded, thick,
exhibit no movement at all)
- OVOID in shape
- Young: 2 nuclei
- Mature: 4 nuclei
TROPHOZOITE
- INVASIVE FORM (PATHOGENIC STAGE)
- In LIQUID STOOL
- 1 NUCLEUS
- Pseudopod:active. progressive and
directional movement
- Centrally located karyosome: Bulls-eye
appearance
- With ingested RBC
- With Charcot-Leyden crystals
TROPHOZOITE
- Motility: Sluggish, nonprogressive
through blunt pseudopod
- Single nucleus with large irregularly
shaped karyosome that is
ECCENTRICALLY LOCATED
- Vacuoles often contain bacteria
- In contrast to E. histolytica, RED
BLOOD CELL INCLUSIONS ARE
NOT PRESENT IN THE
TROPHOZOITES OF E. COLI.
CYST
- Spherical with thick cell wall
- 1-8 NUCLEUS (E.histolytica 1 to 4
nuclei only)
- Cytoplasm contains glycogen mass
- Thin chromatoid bars, often with
pointed to splintered ends
PARASITE
Necator americanus
MORPHOLOGY: LARVA
DIAGNOSTIC STAGE: EGGS IN FECES
RHABDITIFORM
- Feeding Larva (L1)
Molting 2x (L2)
FILARIFORM
Infective stage (L3)
Adult form of Larva
Requires the pulmonary circulation to survive
Stays in the alveolar capillaries
SMALL INTESTINE
o maturation, differentiation and reproduction
PATHOLOGY:
Skin penetration
Vascular/lymphatic penetration
Pulmonary circulation (alveolar capillaries and rupture)
GIT then eggs in stool
DIAGNOSTIC TEST:
SUCKING BLOOD:
Necator (0.15 to 0.25 ml/day/parasite)
Duodenale (0.30 - 0.50 ml/day/parasite)
TREATMENT: Mebendazole and Pyrantel Palmoate
PARASITE
Ancylostoma braziliense
o CAT HOOKWORM
o Cutaneous larva migrans (CLM)
o Creeping eruption
o Never leave the skin
PARASITE
Ancylostoma caninum
o DOG HOOKWORM
o Creeping eruption
o Never leave the skin
BUCCAL CAVITY 3 PAIRS of teeth
DIAGNOSTIC STAGE: FILARIFORM
INFECTIVE STAGE: FILARIFORM (L3)
DEFINITIVE HOST: DOG
PATHOLOGY: Cutaneous Larva Migrans (CLM)
Erythematous and Itchy
Pinpoint lesion
Map-like lesion
INFECTIVE STAGE: Filariform Larva (L3)
LIFE CYCLE: Filariform Larva Only
DIAGNOSTIC TEST: Skin biopsy
TREATMENT: Thiabendazole
PARASITE
Trichuris trichiura (Egg)
Whipwhorm
Barrel/Lemon/Football-shape
With bacillary band
INFECTIVE STAGE: FULLY EMBRYONATED EGG
DIAGNOSTIC STAGE: FERTILIZED EGG
DISEASE: Intestinal obstruction / Allergy
DIAGNOSTIC TEST: Direct fecal smear
TREATMENT: Mebendazole
PARASITE
Trichinella spiralis(Encysted larva)
o Hook worm
o In the muscle
o Encyst or developed only in Striated muscle
o No egg stage
o Trichina worm - Dead end alley infection
(Cannot be transmitted from human to human)
ACCIDENTAL HOST: HUMAN
HABITAT: Striated muscles (Skeletal muscles)
ENCYSTATION: Upper Small Intestine
REPRODUCTION: after mating, males die afterwards and
females dies after passing the larva
INFECTIVE STAGE: ENCYSTED LARVA
DIAGNOSTIC: Muscle biopsy
MOT: Ingestion of infected muscle with encysted larva
TREATMENT:
Mebendazole: Kills the larva
Thiabendazole: Expels the adult worm
PARASITE
Trichinella spiralis(Adult female)
Trichina worm
No egg
dead-end alley infection
Male (mates once, dies); female(pass larva, dies)
PERMANENT HABITAT: Skeletal muscle (Striated muscle)
DISEASE: Trichiniasis
INFECTIVE STAGE: ENCYSTED LARVA
DIAGNOSTIC TEST: Muscle biopsy
MOT: Ingestion of infected muscle with encysted larva
DEFINITIVE HOSTS: Carnivorous or Omnivorous animals
(Cats, Dogs, Hogs, Rats, etc.)
ACCIDENTAL HOST: Humans (cannot be transmitted from
human to human)
PATHOGNOMONIC: With STICHOSOME (Stichocytes nerve
cells)
TREATMENT: Thiabendazole - Expels the adult worm
PARASITE
Capillaria philippinensis (Pudoc worm)
EGGS: - Typical - yellow, moderately thick shell with
striations, with flattened bipolar plug, peanut shaped Atypical thin shelled, without bipolar plugs, with
segmentation, embryonated
INTERMEDIATE HOST: Freshwater fish
INFECTIVE STAGE: Larva
MOT: eating of infected fish with larva stage
HABITAT: Jejunum
DIAGNOSTIC STAGE: typical and atypical eggs in the feces
DIAGNOSTIC TEST: DIRECT FECAL SMEAR
SYMPTOMS:
Intestinal malabsorption (outstanding sign), worst
symptom among aphasmids
Fat malabsorption
Fluid and electrolyte losses
Free passage of plasma protein
Abdominal pain and distention
Cachexia and emancipation
TREATMENT: Mebendazole
PARASITE
Strongyloides stercoralis(Filariform larva)
o THREADWORM
o POINTED
o BUCCAL CAVITY: No teeth nor plates
o DOESNT REQUIRED HUMID SOIL
INFECTIVE STAGE: FILARIFORM (L3) Molts 4 times
DISEASE: Conchin china diarrhea
LIFE CYCLE:
4x molting
Pulmonary circulation
Auto reinfection
Manifest HYPERINFECTION
MOT: Skin Penetration
HABITAT: Small intestine, invade the mucosa up to muscularis layer
but not the serosal layer
DIAGNOSTIC STAGE: EGGS + RHABDITIFORM
LABORATORY: Stool exam, Duodenal & Sputum examination
POPULATION AFFECTED: Adults Institutionalized people
TREATMENT: Thiabendazole
PARASITE
Strongyloides stercoralis (Rhabditiform larva)
o THREADWORM
o STOUTER
o BUCCAL CAVITY: No teeth nor plates
o DOESNT REQUIRED HUMID SOIL
INFECTIVE STAGE: FILARIFORM LARVA (L3)
DISEASE: Conchin china diarrhea
LIFE CYCLE:
4x molting
Pulmonary circulation
Auto reinfection
Manifest HYPERINFECTION
MOT: Skin Penetration
HABITAT: Small intestine, invade the mucosa up to muscularis layer
but not the serosal layer
DIAGNOSTIC STAGE: EGGS + RHABDITIFORM
LABORATORY: Stool exam, Duodenal & Sputum examination
POPULATION: Adult, institutionalized patient
TREATMENT: Thiabendazole
PARASITE
Enterobius vermicularis (Adult female)
PINWORM & SEAT WORM
Presence of with CEPHALIC ALAE & ESOPHAGEAL BULB
Gravid female worms migrate down the intestinal tract and exist
through the anus to deposit eggs on the perianal skin
After deposition, FEMALE DIES
DISEASE: Oxyuriasis/Enterobiasis
COMPLICATION:
Appendicitis
Vaginitis
Endometritis
Salpingitis
Peritonitis
INFECTIVE STAGE: EMBRYONATED EGGS
DIAGNOSTIC STAGE: ADULT WORM OR EGG
PATHOLOGIC STAGE: ADULT
PATHOLOGY: Bleeding diarrhea and prolapsed rectum
DIAGNOSTIC TEST: Scotch adhesive tape swab demonstrate embyonated
ova
MOT: Self-infection, Person to person, Airborne
TREATMENT: Pyrantel Pamoate and Mebendazole (alternative)
PARASITE
Enterobius vermicularis (Eggs)
Most common helminthic infection
One side flattened, other is convex
Oxyuris Vermiculris, Pinworm, Seatworm
INFECTIVE STAGE: EMBRYONATED EGGS
DIAGNOSTIC STAGE: ADULT WORM OR EGG
One side flattened and the other side convex (D-shaped)
Shell has 2 layers
Shape is planoconvex
Contains embryo
RHABDITIFORM LARVA : 140-150 m by 10 m
Esophageal bulb but has no cuticular expansion on the anterior
end.
MOT: Self infection, Person to person, Airborne
DIAGNOSTIC TEST: Scotch adhesive tape swab demonstrate
embyonated ova
TREATMENT: Mebendazole and Pyrantel pamoat
PARASITE
Toxocara canis
Toxocara canis cervical alae is longer than broader compared to
Toxocara cati
Subglobose, moderately thick, coarsely pitted eggshell
DEFINITIVE HOST: DOG
INFECTIVE STAGE: EGG
PATHOLOGIC STAGE: LARVA
ACCIDENTAL HOST: HUMANS
TWO MAIN CLINICAL PRESENTATIONS:
Visceral larva migrans common in Preschool children
Ocular larva migrans
DIAGNOSIS: TISSUE BIOPSY /ELISA
MOT:
By ingesting infective stage eggs from soil
By ingesting larvae in tissues of paratenic hosts that were
infected from soil or by cannibalism or predation
TREATMENT: Albendazole and Mebendazole
PARASITE
Ascaris lumbricoides (Fertilized egg)
Giant Intestinal Roundworm parasitizing human
Golden brown in color
Brodly ovoid with thick and transparent shell
WITH VITELLINE LAYER (Innermost layer) AND
MAMMILATIONS
DISEASE: ASCARIASIS, LOEFFLER SYNDROME
DEFINITIVE HOST: HUMAN
INFECTIVE STAGE: FULLY EMBRYONATED EGG
PATHOGENIC STAGE: Adult, Larva
ADULTS: 3 prominent lips , Each with dentigenous ridge and no
interlabia or alae
DIAGNOSTIC EXAMS:
Direct fecal smear
Demonstration of eggs in feces
TREATMENT: Mebendazole Drug of choice
PARASITE
Ascaris lumbricoides (UNFertilized egg)
Most common human helminthic infection
MORPHOLOGY:
Egg-thick shelled
CLINICAL MANIFESTATION:
ADULT WORMS usually causes NO SYMPTOMS
Loefflers syndrome (Cough, dyspnea, hemoptysis and
eosinophilic pneumonitis)
DEFINITIVE HOST: HUMAN
INFECTIVE STAGE: FULLY EMBRYONATED EGG
DIAGNOSIS:
Direct Fecal Smear
Demonstration of eggs in feces
TREATMENT: Mebendazole/Albendazole
DISEASE
INTERMEDIATE HOST
DIAGNOSTIC STAGE
INFECTIVE STAGE
PERIODICITY
BODY CURVES
PRESENCE/ABSENCE OF
TRANSPARENT SHEATH
ARRANGEMENT OF BODY
NUCLEI
DIAGNOSTIC EXAM
DRUG OF CHOICE
Lymphatic Filariasis
Anopheles, Culex, Aedes
Microfilariae
L3
Nocturnal
Graceful curves, bluntly rounded
anterior and pointed posterior
(+)
Lymphatic Filariasis
Mansonia
Microfilariae
L3
Nocturnal
Stiff, kinky body
(+)
NO INTERMEDIATE HOST!!
INFECTIVE STAGE: CERCOCYTIS
DIAGNOSTIC STAGE: EGGS WITH 6 HOOKLETS IN THE FECES
HABITAT: ILEUM
DEFINITIVE HOST: HUMAN, MICE AND RATS
MOT: INGESTION
TREATMENT: PRAZIQUANTE