Association Between Helicobacter Pylori Infection and
estimated Glomerolus Filtration Rate
ABSTRACTS Maharani K*, Damayanti A**, Kusnanto P**, Pramana TY**, Harmono T** *Resident Internal Medicine Medical Faculty Sebelas Maret University **Staff of Gastroenterohepatology Department Sebelas Maret University Background : It is generally known that Helicobacter pylori (H Pilory) infection is directly associated with progression of renal dysfunction. Many reports suggest that chronic H pilory infections may be associated with atherosclerosis and inflammations. Atherosclerosis and inflammation will decrease renal function. The aim of this study was to investigate the association between Helicobacter pilory infection and creatinin clearance in patient with dyspepsia. Methods : This retrospective study was conducted between Januari 2013 until Desember 2013 in Moewardi Hospital Surakarta. Inclusion criteria was dyspepsia syndrom. Exclusion criteria was chronic kidney disease, chronic liver disease, malignancy, infection. Modification of diet in renal disease equation was used to count estimated glomerolus filtration rate (eGFR).H pylory infection define by positive biopsi specimen from endoscopy esofago gastro duodenal. Statistical analysis using independence t test and pearson correlation test with SPSS 20, significant if p<0,05. Result : There were 60 patient, 20 with positive H pilory and 40 with negative H pilory. The mean creatinin was 1,12 + 0,654 mg/dL, mean ureum 30,45 + 30,34, and mean eGFR 61,34 + 21,34 ml/m2 (satuan salah). There was negative correlation between h pilory infection and eGFR in patient with syndrom dyspepsia (p:0,002, r:-0,453) Conclusion : This study demonstrated that H pilory infection was associated with lower eGFR in patient with dyspepsia syndrom Key: Dyspepsia, H. Pylori, Creatin Clearance Test
The Association Between Ferritin Serum and Degree of
Severity Cirrhotic By Child Pugh Turcotte Score ABSTRACTS Adhyaksari A*, Damayanti A**, Kusnanto P**, Pramana TY**, Harmono T** *Resident Internal Medicine Medical Faculty Sebelas Maret University **Staff of Gastroenterohepatology Department Sebelas Maret University Background : Chronic liver disease causes aberrant formation of fibrous tissue that impedes normal liver function, ultimately resulting in liver cirrhosis. Iron uptake can occur within the hepatic parenchyme or within the various nodules that form in a cirrhotic liver, termed siderotic nodules, this parenchyme changes will aggravate the decrease of liver function. The aim of this study was to investigate the association between ferritin serum and degree of severity cirrhotic by child pugh turcotte score Methods : This retrospective study was conducted between Januari 2013 until Desember 2013 in Moewardi Hospital Surakarta. Inclusion criteria was cirhhotic patient. Exclusion criteria was chronic kidney disease, infection, metabolic diseases, and chronic heart failure. Degree severity of cirhhotic was measured by Child Pugh Turcotte score. Statistical analysis using independence t-test and pearson correlation test with SPSS 20, significant if p < 0,05. Result : There was 60 patient, 35 male and 25 female. Mean age was 48,34 + 12,23. There was 30 patient with hepatitis B, 20 patient with hepatitis C. The child pugh turcotte score was 12 patient (child pugh A), 28 patient (child pugh B), and 20 patient (child pugh C). There was positive correlation between ferritin serum and child pugh turcotte score (p : 0,002, r : -0,453) Conclusion : This study demonstrated that increase ferritin serum was associated with severity liver disease measured by Child Pugh Turcotte score Key : Cirrhotic, Ferritin serum, Child Pugh Turcotte Score, Hepatitis