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A-filtration
B-humidification
*medical scenario:
During one of your hospital rotations you observe a resident performing pleural
tap to obtain a sample of pleural fluid. The resident inserts the needle near the
lower border of 8th rib at the right ant. Axillary line and withdraws small
quantity of pleural fluid. The next day, during your rounds, the patient
complains of tingling and numbness of the skin of his chest from the level on 8th
rib down toward the umbilicus of the right side.
Q1: what specific structure was likely to be damaged by the needle?
Intercostal nerve
Q2: list two other structures that may also be damaged?
Intercostal vein and artery
Q3: these structures are running in which muscle layers?
Q4: name the safe place where the resident should insert the needle to avoid
damaging these structures?
*the rule says we should insert the needle superior to the inferior rib* so the
resident has to insert the needle superior to the 9th rib.
Scenario2
Q5-7 are related to this clinical vignette.
A 65-year-old male resident of Riyadh visited the ER of a hospital, complaining
of difficulty in breathing and chest tightness for the past year. He is a heavy
smoker and have chorionic cough, producing several tablespoons of white
sputum each morning. He has no known cardiac disease but he is worried that
he may have pulmonary disease. The physician ordered spirometry tests. Test
results are shown below before and after the administration of an inhaled
bronchodilator
PFT
FVC (L)
FEV1 (L)
FEV1/FVC%
FEF 25%
75% (L/S)
Before Bronchodilator
Actual value
%predicted
After Bronchodilator
Actual value
%Change
4
2.4
60
2
4.2
2.9
68
2.4
103
80
51
5
20
20
Q6: which two PFT results support your answer? EV/FVC is low 2) both
FEV and FVC are low (FEF Is low)
Q7: what is your diagnosis? Asthma
__________________________________________________
TBL2
1-Which of the following occurs during normal quiet breathing?
A-respiratory gasps
B- Phrenic Motoneurons fire once every minute
C-firing of the phrenic motoneurons is rhythmic
2-early air way collapse during expiration in obstructive disease leads to
air trapping. What would you expect to see in that patient?
A-increased PaO2
B-increased PACO2
C- Increased FEV1
3-in spinal cord and central nervous system injuries
A-injury is below C5 level, quiet breathing is not affected
B- Injury is above C3 level, quiet breathing is not affected
C- Injury is above C2 level, quiet breathing is not affected
4-which of the conditions would produce the greatest stimulation of the
chemosensitive area in the medulla
A- Increase in arterial PO2
B- Increase in arterial H+
C- Increase in arterial PCO2
Medical scenario
A 67-year-old developed a worsening cough over several months and when the
septum began to show streaks of blood, he consulted a physician, the patient gave a
history of smoking cigarettes for 40 years and recently had noticed that his voice
had become hoarse. An x-ray of the chest revealed an irregularly shaped density in
the hilar region of the left lung.
Q1-how might the hoarseness relate to the location of the density?
Affected the recurrent laryngeal nerve causing hoarseness.
Q2-list 2 structures situated in the vicinity of hailer region of the lung?
Pulmonary A. pulmonary V.
Q3-what is the nerve supply of mediastinal pleura against which the density lies?
Phrenic N.
Q4- if density obstructed the left upper lobe bronchus, what would the affect be the
lung would collapse
*Scenario2
During a road traffic accident (RTA) a 25-year-old driver hit his head against a
wind screen. On arrival at the ER department of nearby hospital his pulse was 60
bpm and respiratory rate was 8 breaths per minute. His breathing was deep and his
blood labored. He also had brain edema.
His blood gases revealed:
______________________________________________________
TBL3
1-hypoxic vasoconstriction in the lung will result as a consequence of which of the
following physiological changes below?
A- Increased PAO2
B- Decreased PACO2
C- Increased PH
D- Decreased PAO2
2-which condition below will lead to a rise in pulmonary wedge pressure (PCWP)
A- A rise in right atrial pressure
B- A rise in left atrial pressure
C- A drop in pulmonary capillary pressure
D- A drop in left atria pressure
3-which of the following changes below will enhance the diffusion of a gas
exchange into the blood
A-decreased solubility (S) of the gas
B-increased diffusion distance
C-increased pressure differential
Scenario 2
A 57 year old man who has smoked two packed of cigarettes daily for the past 30
years present to the ER with a substernal pressure radiating down his left arm and
feeling of indigestion. The pain lasted 30 min and was accompanied by shortness
of breath. He has an intermittent cough that occasionally is productive of teaspoon
of septum in the morning.
In the emergency room the patient appears to be in moderate respiratory distress
and is complaining of chest tightness. His blood pressure is 140/90 mm Hg. His
pulse is 110 bpm, and his respiration are 30 breaths per min. the patient is
dyspneic. Examination of the chest reveals rales at both bases. His blood gases
while breathing room air reveal:
PaCO2= 32 mm Hg (normal 35-45)
PaO2= 60mm Hg (normal 80-100)
PH=7.47
His white blood cell count is 15,600 per mm (4300- 10,800)
Hb 14.3 (normal 13.5- 17.5)
The patient is admitted to the intensive care unit and the following pressure is
measured:
Pulmonary artery occlusion pressure (PAOP) or pulmonary capillary wedge
pressure (PCWP): 28 mm Hg (8-12 mm Hg)
Q1: list three possible causes of dyspnea in this patient?
1) Accumulation of mucus and fluid 2) smoking history 3) low oxygen
Q2: what does the present of rales tell you?
It indicates the presence of fluid in the cavity
Q3: list two causes of hypoxemia?
1) A low V/Q
2) The mucus/fluid barrier preventing o2 diffusion
Q5: based on the above observations, what is your diagnosis and what treatment
can you think of?
Chronic bronchitis and left heart failure (so this is cardiogenic)
Treatment: diuretics to release fluids, oral steroids and oxygen.
Good Luck =)
Done by:
Asmaa Dalhi