2015 DECEMBER MCQ

1. PTH active region - N terminus

2. Lymes disease presenting with facial palsy, AV block, - early disseminated disease
3. Metamorphosia caused by EBV
4. Kawasaki which is not a DD - Enterovirus
5. HFMD caused by coksackie virus
6. Rash not seen in face - IMN, rickettsia, measles
7. Collodion baby - Tay Sachs disease
8. 1:1 mixing plasma corrects aPTT in factor 7 def, factor 8 inhibitor,
9. Reptilase time
10. Ichthyosis and corneal deposits in baby and mother - X linked iccthyosis
11. Severe disease - epidermolysis bullosa AD type, EB herlitz type, EB non herlitz type, EB
simplex
12. Mitochondrial illness - Reye's syndrome
13. Norway Indian partnership initiative to appoint women in hospital for new born care Yashoda, ASHA, Janani, ,bagyalakshmi
14. MDG under 5 mortality in 2015 - 40
15. 10 yr old female with fever, cola coloured urine, hypertension, low serum c3, biopsy
extensive glomerular proliferation, c3 deposits IgM,IgG and IgA deposits in
immunofluroscence - PIGN, membranous nephropathy, MPGN, SLE
16. Sinusitis + LRTI + renal manifestation - wegeners
17. Heiner's syn - pulmonary hemosiderosis
18. Catamenial pneumothorax associated with diaphragmatic defects
19. Hypocalcemia + deafness + VUR - HDR/GATA mutation
20. Progeria with ulcers - Werner syndrome
21. RTA + Rickets + cataract - Lowe syndrome

22. Unilateral gynaecomastia in 10 yr without history of drug intake, all inv normal - Rx
Reassurance
23. Unilateral thelarche in 1 yr old female, hormonal study normal - follow up
24. 17 OH progesterone screening done at - birth, 1 week, 2 week
25. Femur head ossifies at - 4+/- 2 months
26. Ossification centre present at birth - lower end of femur
27. Breast tanner III started GnRH analogue - which is true? Breast size decreases, pubic hair
decreases, ht 1 SD lesser than MPH, all of the above
28. 7.5 years, bone age 10, estradiol increased after GnRH stimulation - true precocious
puberty
29. Peripheral precocious puberty in boy treatment option - ketakonazole
30. Type 1 DM, with fever and abd pain with calcium 16, PTH low, phosphorus 3, ALP 230
cause- pseudohypoparathyroidism, pseudohyperparathyroidism, multiple endocrine hypoplasia
31. Vit D excess all except - diarrhoea, hypertension, hypercalcemia, pancreatitis
32. Vit A toxicity all except - anasarca, pseudotumor cerebri, desquamation, widening of sutures
33. Vit E deficiency all except - antr horn cell degeneration, hemolysis, posterior column defect,
pigmentary retinopathy
34. Hyperoxaliuria treatment - pyridoxine, vit c
35. Hypertensive emergency bp 160/100 with seizures - Rx sodium nitroprusside and
neuroimaging
36. Hypogonadism seen with Zinc deficiency
37. Fetal growth influenced by all except glucocorticoids, GH, insulin, thyroxine
38. Hypoglycemia, microphallus, prolongation of jaundice - hypopituitarism
39. 6 yr old hypothyroidism due to lymphocytic thyroiditis with signs of delayed puberty
probable finding - increased FSH/LH, mild elevation in TSH, increase in sella turcica
40. Tall stature Rx - Pegvisomant
41. Growth hormone clonidine test GH >7??
42. GH > 14, short stature +features? cause - ? Reiger hall pallister,GH excess

43. NTD recurrence folic acid dosage - 4 mg/day

44. NTD recurrence risk when one parent is affected 3-5%
45. Downs syndrome 95% trisomy, 4% translocation and 1% mosaicism
46. Diabetes insipidus option with plasma osmolaity >300 and urine osmolaity <300
47. Glucose challenge test increase in GH >5ng/ml
48. Skin manifestations + seizures + acidosis multiple carboxylase deficiency
49. Dengue warning signs all except (WHO criteria) tourniquette test
50. Babesiosis transmitted by hard tick
51. Rat bite fever organism streptobacillus moniliformis
52. Sickle cell anemia chest crisis organism mycoplasma pneumonia
53. Pertussis treatment Azithromycin
54. Respiratory epithelium attachment and inhibition of ciliary function Chlamydia,
mycoplasma, Hib, pneumococcus
55. Hypokalemia + metabolic alkalosis + normal BP Gitelman syndrome
56. Liddle syndrome treatment Triamterene
57. Hypokalemia + metabolic alkalosis + SNHL which gene - Barrtin
58. Hypernatremia seen in all except SIADH
59. MCC of hypertension by kidney PSGN,RVT, Renal Artery Stenosis
60. Hypervolemic Hyponatremia seen in all except obstructive uropathy, nephrotic syndrome,
heart failure, increased capillary leak due to sepsis
61. Hyperkalemia caused by all except Salbutamol
62. Hypokalemia ??

63. Refeeding syndrome hypophosphatemia

64. Drug causing Hypertrophic pyloric stenosis erythromycin
65. Replacement fluid of choice in emesis
66. Conventional microscopy cannot detect Treponema pallidum
67. Dog bite followed by infection possible organism Pasteurella multicoda
68. Brucella DOC Doxycycline
69. Duffy coat antigen Plasmodium vivax
70. DOC for uncomplicated strongyloidasis Iveremctin, Thiabendazole, nitazonaxanide,
Pyrantel pamoate
71. Dientamoeba coinfection is seen in Ankylostoma, Ascariasis
72. Neurodevelopment better indicator- BERA, VEP, SSEP, aEEG
73. ROP intravitreal anti VEGF Bevacizumab
74. PNH defect anchor glycolipid defect with complement mediated lysis
75. Chronic respiratory alkalosis compensation which is seen decreased H+ production,
increased acetoacetate, increased lactate, increase in catecholamine production
76. Acute respiratory acidosis compensation in a neonate for1mmhg increase in pCO2 0.1
increase in HCO377. PROBIT study is for probiotics
78. HIE which statement is true? MRS increased aspartate a poor prognosis, CKBBelevation
poor predictor, cardiac tropinin I levels as predictor
79. Maximum magnesium absorption is seen in stomach, small intestine, large intestine, all
parts of intestine equally

80. Hepatic encephalopathy MCC of death sepsis, brain stem herniation, bleeding
81. Fever, hematuria, hypertension, abd mass, ambiguous genitalia wilms, neuroblastoma,
testicular malignancy
82. In ambiguous genitalia all true except 10% dextrose as fluid for resuscitation , lng term
need for glucocorticoids and mineralocorticoids, HCO3- may be needed for treatment
83. Choanal atresia true statement most common anomaly, 50% associated with CHARGE
syndrome, bilateral asymptomatic at birth, can be diagnosed with mid facial xray definitely
84. Obesity + hypertension + acanthosis PCOS
85. Hungry bone syndrome MCC hyperparathyroidectomy
86. Retinoblastoma bilateral Rb usual diagnosis 15 months, most common manifestation is
strabismus, biopsy should be done before enucleation, Rb unilateral unifocal more common
87. Subluxation with secondary glaucoma - homocystinuria
88. BMI >31 obese, undernutrition, stunted
89. 1mm hg pO2 how much will be dissolved in blood 0.3, 0.03, 0.003, 0.00003
90. FRC of newborn 20ml/kg, 30, 40, 50
91. LMA all true except - proven inall newborns, facilitates ET insertion, no need of laryngoscopy
92. ASD early surgery is indicated in CCF controlled with medication, BPD on O2 dependence,
none of the above
93. L/H ratio 100% survival with >1.4
94. Short stature, pulmonary stenosis Noonans syndrome
95. Turners syndrome most common renal anomaly horse shoe kidney
96. 4 yr old female, absent uterus, abd testes XY + reared as female and gonadectomy

97. Female, bilateral inguinal hernia, no uterus, diagnosis Androgrn Insensitivity syndrome
98. Splenectomy decreased chance of infection with trauma, hodgkins lymphoma, WAS,
hemolytic anemia
99. MC adolescent girl problem primary dysmennorrhoea, secondary dysmenorhoea, PMS,
100.X linked Wiskot Aldrich syndrome
101.Congenital varicella classical lesion cicatricial skin lesions
102.Human genome 30000 genes
103.3 time constants give how much pressure equilibrium 95%
104.What happens to time constant if resistance increases and time constant remains the
same? increases
105.CPAP which is best flow CPAP, bubble CPAP, HFNC, Ventilatory CPAP
106.Percentage of water in plasma 1, 5, 7, 10
107.Osmolar gap >10 mosm/L
108.Long QT syndrome most common cause in newborn hypocalcemia, jervell lange
nielson syndrome
109.Most common cause of sudden asymptomatic death hypertrophic cardiomyopathy
110.Renoprotective drug ACE inhibitor
111.Not a PDD Rett, Asperger, Childhood disintegrative disorder, reactive inhibitory disorder
112.Development order given which is wrong? Order - circle followed by vertical strokes wrong
113.Handedness 3 years
114.Hand regard persisting beyond 5 months abnormal

115.9 months order of examination gross motor, fine motor, language, hearing and vision
116.Banging cubes at what age ? 12 months
117.Which is receptive language delay? 3 words at 18 months, no mama dada at 18 months,
standing alone at 15mins
118.Red flag sign - vocalization at 5 months
119.Heart development looping ventral and to right
120.Skin completely develops at 20, 22, 24, 28 weeks
121.Preterm lids closure for bright light when 28 weeks, 32 weeks
122.Skin care scale AWHONN 31 week PT, dry skin, erythema < 50% skin surface,scaling
1,5,7,9
123.Central pontine myelinosis is seen with treatment of hyponatremia
124.Sickle cell anemia TAMM score blood flow velocity increased of stroke >200
125.Risk of stroke HbS has to be decreased to <30%
126.Bite cells seen in G6PD deficiency
127.Transfusion GVHD prevention irradiation
128.Industrialized countries most common shigella S.sonnei
129.Increased ICP, normal CSF, small to normal ventricles pseudo tumor cerebri
130.Smallest biological organisms prions
131.Bioterrorism type of botulism inhalational, infantile, food borne, wound
132.Normal newborn oxygen consumption?
133.Keyhole sign in antenatal scan PUV

134.Renal scarring scan DMSA

135.10 moths, Hydronephrosis VUR grade 4, 2 times UTI DMSA & antibiotics, DMSA &
surgery
136.Vincents curtsy seen in detrusor dysynergia
137.PDA in preterm all except aorta LA square root ratio, all should be treated immediately, can
cause apnea
138.Measles warthin Finkkely cells seen in oral mucosa, skin, appendix, lung
139.GERD what cells in mucosa eosinophils,lymphocytes, monocytes, neutrophils
140.Newborn fungal infection which is false twice weekly flucanazole 3mg/kg to newborn, all
NICU inmates should be given antifungal prophylaxis
141.Immune compromised individual, fever, hypoxia, BAL gomorri silver stain positive
next step?- Rx with trimethoprim-sulfamethaoxazole
142.Dendritic keratitis cause HSV
143.Which is true for growth growth from birth to adulthood, early life hyperplasiatakes place,
aged cells replaced by new cells
144.Question on genetic polymorphism
145.Maternal disomy seen with Praderwilli syndrome
146.Single gene mutation investigation of choice- FISH, PCR, Karyotyping
147.Unexplained MR Investigation of choice microarray
148.Breast hypoplasia seen in all except hyperthyroidism, turners, adrenal tumor
149.Carbon monoxide in blood and expired air - dynamic measure of hemolysis
150.Recombinant GH therapy with hip pain Slipped capital femoral epiphysis

151.Sickle cell trait definite association exertional rhabdomyolysis,cholelithiasis, avascular

necrosis
152.Piece meal necrosis of liver seen in chronic active hepatitis
153.Hepatocellular failure seen in tyrosinemia
154.Anti HBs, anti HBc indicates recovered infection
155.Essential mixed cryoglobulinemia seen in Hep C infection
156.PAPPA all except purulent conjunctivitis
157.Dense deposit disease partial lipodystrophy
158.Streptococcal skin antibody which is best anti DNAase
159.Adrenal incidentaloma
160.Hypoplastic right heart syndrome tricuspid atresia
161.3 week old, BW 3.9kg NVD, diminished right hand movements since birth, no abduction,
palmar grasp and poor moro present. mRI shows psedomyelocoeles,EMG fibrillatory
waves. Probable lesion upper brachial plexus injury neuropraxia, upper brachial plexus total
avulsion, total brachial plexus injury with neuropraxia, total brachial plexus injury with root
avulsion
162.Hypophosatemia inheritance XLD
163.Levetiracetam dose in status epilepticus? 5-10, 10-15, 20-30, 50-60
164.Marker of kidney injury beta2 microglobulin
165.TTKG represents ?conservation of potassium in cortical collecting duct
166.Drug acting on NKCC channel furosemide

167.Hemangioma which is true more in males, more in term, increases till 2 yrs, kassabach
meritt syndrome not a classical finding
168.Repiratory burst assay is used for diagnosis of phagocytic defects
169.Which is not a T cell testing IgM, IgA levels
170.Placental transfer all except increased

cord IgG levels indicates in utero infection,

increased IgM and IgA indicates inutero infection, SGA decreased levels of Ig when compared
with baby of same age
171.Most common inherited phagocytic defect myeloperoxidase deficiency
172.Meningococcal infection seen in complement factor 7 deficiency
173.Meningococcal infection after 5 days antibiotics sudden swelling of right knee. Causes
hemorrhage into joint, septic arthritis, immune complex mediated process, immune
suppression mediated
174.Amoxicillin for 7 days in URI followed by blood in stools. Common cause
pseudomembranous colitis, rectal polyposis, bacillary dysentery
175.Transport of amino acids and calcium across placenta - simple diffusion,facilitated
diffusion, pinocytosis, active transport
176.Velamentous insertion of cord leads to vasa previa, oligohydramnios, multiple congenital
anomalies
177.GERD best non surgical treatment PPI
178.Best transfusion for sickle cell anemia erythracytapharesis
179.Suck and swallow cranial nerves
180.Kernicterus stains which part of brain? substansia nigra
181.Impending sign of respiratory failure grunt

182.MCC of neonatal mortality prematurity, birth asphyxia,

183.Gadchiroli study is for?
184.Incubator humidity for preterms in the first seven days 75-80%
185.<1kg preterm maximum protein used in TPN according to ISPHAGAN guidelines?