Dr. M.

Hafizur Rahman
Assistant Professor
(HEC Approved PhD Supervisor)
Dr. Panjwani Center for Molecular Medicine and Drug Research (PCMD)
International Center for Chemical and Biological Sciences (ICCBS)
University of Karachi, Karachi-75270, Pakistan
Phone: 021-4824934-6 ext. 311
Email: hafizpcmd@yahoo.com; hafizur.rahman@iccs.edu
Number of Publications:
Impact Factor:
Total Citation:

10
13.481 (ISI Web of Knowledge)
45 (ISI Web of Knowledge/Scopus)

EDUCATION
PhD (Molecular Genetics), 2005
Kumamoto University, Japan
Thesis: Modulation of Chaperone Activities of Hsp70s by a Mammalian DnaJ/Hsp40 Homolog, DjA4
MSc (Biochemistry), 1995
University of Dhaka, Dhaka, Bangladesh
Thesis: Pathogenesis of Platelet Hyperaggregability in Diabetes Mellitus
BSc (Biochemistry), 1994
University of Dhaka, Dhaka, Bangladesh
AWARDS
2011: Awarded Travel and Accommodation Grant from International Diabetes Federation (IDF)
to attend the World Diabetes Congress going to be held on December 4-8, 2011, Dubai,
UAE
2010: Awarded Travel Grant from ANRAP to attend the 6th International Seminar on Plant
Materials as a Source of Antidiabetic Agents, January 15-17, 2010, Dhaka, Bangladesh.
2000-2005: Monbusho Fellowship, Ministry of Education, Science and Technology, Japan.

1999-2000: NST Fellowship, Ministry of Science and Technology, Bangladesh.

PROFESSIONAL APPOINMENTS / EXPERIENCES

Assistant Professor
PCMD, ICCBS, University of Karachi, Pakistan.
Research Officer
PCMD, ICCBS, University of Karachi, Pakistan
Postdoctoral Fellow
PCMD, ICCBS, University of Karachi, Pakistan.
Visiting Professor (HEC)
PCMD, ICCBS, University of Karachi, Pakistan.
Postdoctoral Fellow
Bangladesh Institute of Research and Rehabilitation in Diabetes,
Endocrine and Metabolic Disorders (BIRDEM), Dhaka, Bangladesh.
Scientific Officer
BIRDEM, Dhaka, Bangladesh.

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September 2010 - present

August 2008 - September 2010
November 2007 - July 2008
March 2007 - November 2007
April 2005 - March 2007

March 1997 - September 2000

TEACHING EXPERIENCE
June 2007- to date: Teaching Molecular Medicine course for the MS/PhD program at PCMD,
ICCBS, University of Karachi, Pakistan.
Jan - Dec, 2006: Taught Biotechnology in Master of Science (MS) course (36 hours of lectures),
North South University, Dhaka, Bangladesh.
GRANTS
A research grant titled Discovery of Insulin Secretagogues from Natural and Synthetic
Compounds in In vitro and In vivo has been submitted to HEC, Pakistan on April 19, 2011.
A research grant titled Evaluation and Comparison of In vivo and In vitro Antiglycation Activity
of Dietary Agents has been submitted to HEC, Pakistan on July 16, 2011.
A research grant titled Modulatory Effects of Cinnamomum cassia and Aegle marmelos on
Protein Glycation and -cell Function in Streptozotocin-induced Diabetic Rats has been
submitted to TWAS, Trieste, Italy on August 30, 2011.
PUBLICATIONS
1. Hafizur RM, Babiker R, Yagi S, Chrishti S, and Choudhary MI. Antidiabetic and antioxidant
activities of methanolic extract of Geigeria alata (DC.) roots on streptozotocin-induced diabetic
rats. Submitted for publication in the Natural Product Research
2. Hafizur RM, Kabir N, and Chishti S. Asparagus officinalis extract controls blood glucose by
improving insulin secretion and -cell function in streptozotocin-induced type 2 diabetic rats.
Submitted for publication in the British Journal of Nutrition
3. Shefin SM, Faruque MO, Hafizur RM, Islam NM, Hossain MM, Latif ZA, Akter S, Nahar Q,
and Ali L. Insulin Secretory Capacity in the Normoglycemic First Degree Relatives of
Bangladeshi Prediabetes Subjects. International Journal of Diabetes Mellitus (in press).
4. Islam MN, Hossain M, Hafizur RM, Khan I, Rashid MA, Shefin MS, Haque ME, Faruque MO,
and Ali L. Ratio of fasting glucose to adiponectin is an important predictor for the development of
type 2 diabetes. Journal of Diabetology (in press)
5. Karim MR, Zinnat R, Akter S, Islam S, Biswas KB, Rahman MH, and Ali L (2011)
Characterization of insulin secretion in type 2 diabetic subjects. Bang J Med Biochem 2, 2125.
6. Hafizur RM, Kabir N, and Chishti S (2011) Modulation of pancreatic -cells in neonatally
streptozotocin-induced type 2 diabetic rats by ethanolic extract of Momordica charantia fruit
pulp. Natural Product Research 25, 353 -367
7. Rahman MH, Hafizur RM, Nahar Q, Khan AR, and Ali L (2010) Insulin secretion and
sensitivity in Bangladeshi prediabetic subjects. J Diabetes Complications 24, 37-42
8. Ali ME, Ahmed MU, Alam S, and Rahman MH (2008) HLA-A, -B and -DRB1 allele
frequencies in the Bangladeshi population. Tissue Antigens 72, 115-119
9. Sardar K, Khatun UHS, Rahman MH, Rashid MA, Faruque O, and Ali L (2008) Hemodynamic,
glycemic and electrolyte response to total abdominal hysterectomy under general anesthesia in
type 2 diabetic subjects. Diab Endocr J 2008, 36, 8-12
10. Hafizur RM, Yano M, Gotoh T, Mori M, and Terada K (2004) Modulation of Chaperone
Activities of Hsp70 and Hsp70-2 by a Mammalian DnaJ/Hsp40 Homolog, DjA4. J Biochem 135,
193-200
11. Fatema K, Ali L, Rahman MH, Parvin S, and Hassan Z (2003) Serum glucose and insulin
response to mango and papaya in type 2 diabetic subjects. Nutrition Research 23, 9-14

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12. Abdul KM, Terada K, Gotoh T, Hafizur RM, and Mori M (2002) Characterization and functional
analysis of a heart-enriched DnaJ/Hsp40 homolog dj4/DjA4. Cell Stress Chaperones 7, 156-166
ABSTRACTS / SEMINARS / SYMPOSIA / WORKSHOP ATTENDED
1. M. Hafizur Rahman*, Shahrukh Momin, Nurul Kabir and M. Iqbal Choudhary. Cinnamomum
cassia Extract Reduces the Formation of Advanced Glycation End Products in Diabetic Model
Rats. 9th International and 21st National Chemistry Conference-2011, March 14-16, 2011,
Karachi, Pakistan.
2. M. Hafizur Rahman*, Nurul Kabir and Sidra Chishti. Development of Diabetic Models for
Investigating Anti-diabetic Natural Products. The 12th International Symposium on Natural
Product Chemistry, November 22-25, 2010, Karachi, Pakistan.
3. M. Hafizur Rahman*, Randa Babiker, Sidra Chishtia, Sakina Yagi and M. Iqbal Choudhary.
Anti-diabetic Activity of Methanol Extract of Geigeria alata (DC.) Roots on Streptozotocininduced Diabetic Rats. The 12th International Symposium on Natural Product Chemistry,
November 22 -25, 2010, Karachi, Pakistan.
4. Shahrukh Momin, M. Hafizur Rahman, Abdul Hameed, Sidra Chishti, Maryam Bano, Nurul
Kabir and M. Iqbal Choudhary. Antiglycation Activity of Asparagus officinalis and Cinnamomum
cassia in Diabetic Rat Models. The 12th International Symposium on Natural Product Chemistry,
November 22 -25, 2010, Karachi, Pakistan.
5. Islam MN, Hossain MM, Khan I, Shefin SM, Rashid MA, Hafizur RM, Faruque MO and Ali L.
Ratio of fasting glucose to adiponectin is an important predictor for the development of type 2
diabetes. The 7th Annual World Congress on Insulin Resistance (WCIR): November 5-7, 2009,
San Francisco, Ca, USA
6. Md. Hafizur Rahman*. Modulation of pancreatic -cells in type 2 diabetic rats by ethanolic
extract of Momordica charantia fruit pulp. The 6th International Seminar on Plant Materials as a
Source of Antidiabetic Agents, January 15-17, 2010, Dhaka, Bangladesh.
7. Md. Hafizur Rahman*. Immunohistochemical Studies on Pancreatic -cells in Streptozotocininduced Type 2 Diabetic Rats treated with Momordica charantia Extract. The 2nd International
Symposium-cum-Training Course on Molecular Medicine and Drug Research, January 12-15,
2009, Karachi, Pakistan.
8. Md. Hafizur Rahman*, Nurul Kabir, Sidra Chishti and Mohammed Mosihuzzaman.
Immunohistochemical Characterization of Pancreatic Islets in Streptozotocin-induced Diabetic
Wistar Rat. The 11th International Symposium on Natural Product Chemistry, October 29November 1, 2008, Karachi, Pakistan.
9. Huneza Khan, Suad Naheed, Md. Hafizur Rahman and Mohammed Mosihuzzaman.
Development of Diabetic Rat Models. The 11th International Symposium on Natural Product
Chemistry, October 29- November 1, 2008, Karachi, Pakistan.
10. Shefin SM, Hafizur RM, Islam NM, Hossain MM, Latif ZA, Akter S, Nahar Q, Islam S, Hassan
K, Faruque MO and Ali L. Insulin secretion and insulin sensitivity in first degree relatives of
subjects with impaired glucose regulation. The 44th Annual Meeting of the EASD, September 611, 2008, Rome, Italy.
11. Ali L, Sardar K, Khatun UHS, Rahman MH, Rashid MA. Glycemic and insulinaemic response
during lower abdominal surgery under general anesthesia in type 2 diabetic subjects.
Diabetologia, 2007 (suppl 1), S275
12. Rahman MH, Hafizur RM, Huq F, Nahar Q, Tazib T, Khan AR and Ali L. Insulin secretion and
insulin sensitivity in subjects with impaired glucose regulation. Diabetologia, 2006 (suppl 1), 451
13. Md. Ashraful Islam, Md. Hafizur Rahman, Nazlee Sharmin, Safiqul Islam, Tasnima Sarowar.
Need for Production of Pharmaceutical and Industrial Proteins- A Bangladesh Prospectus.
Promotion of Biotechnology in Bangladesh: National and International Perspectives, April 6-8,
2007, Dhaka, Bangladesh.

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14. Attended the Life Sciences Workshop on Research and Drug Development, March 11-12, 2008,
Bahria University, Karachi, Pakistan.
15. Md. Hafizur Rahman*. Biopharmaceuticals: Bangladesh Prospectus. The 1st Congress of
Young Biotechnologist of Bangladesh (YBB), December 2006, Dhaka, Bangladesh.
16. Attended the COMSTECH Workshop on Industrial Biotechnology: Connecting Business,
Academia Nov 6-17, 2006, Islamabad, Pakistan.
17. Md. Hafizur Rahman*, Kazutoyo Terada. Chaperone Function of a Newly Found DnaJ/Hsp40
Homolog, DjA4. The 10th Annual General Meeting of Bangladesh Society for Biochemistry &
Molecular Biology, July 29, 2006, Dhaka, Bangladesh.
18. Md. Hafizur Rahman*. Heat Shock Proteins and Diabetes Mellitus (Invited Lecture). The 11th
Diabetes and Endocrine Conference, March 2-4, 2006, Dhaka, Bangladesh.
19. Hafizur RM*, Rahman MH, Huq F, Khan AR, Ali L. Insulin secretion and insulin sensitivity in
subjects with impaired glucose regulation. The Clinical Biochemists Association of India,
December 18-21, 2005, Patna, India.
20. Huq F, Akhter S, Hafizur RM, Rahman MK, Ali L. Insulinemic and proinsulinemic status in
subjects with impaired glucose regulation. The Clinical Biochemists Association of India,
December 18-21, 2005, Patna, India.
21. Hafizur RM*, Yano M, Gotoh T, Mori M, and Terada K. Regulation of Hsp70 and Hsp70-2
activities by a new mammalian DnaJ/Hsp40 homolog, DjA4. The Kyushu Regional Scientific
Meeting of the Japanese Biochemical Society, May 29-30, 2004, Kumamoto, Japan.
22. Terada K, Hafizur RM, Mori M. Cochaperone functions of Type I DnaJ homologues. The 26th
Annual Meeting of the Molecular Biology Society of Japan, December 10-13, 2003, Kobe,
Japan.
23. Hafizur RM*, Gotoh T, Yano M, Mori M, and Terada K. Modulation of chaperone activities of
Hsp70 and Hsp70-2 by a mammalian DnaJ/Hsp40 homolog, DjA4. The 76th Annual Meeting of
the Japanese Biochemical Society, October 15-18, 2003, Tokyo, Japan.
24. Abdul KM, Terada K, Gotoh T, Hafizur RM, and Mori M. Characterization and functional
analysis of a heart-enriched DnaJ/Hsp40 homolog dj4/DjA4. CSHS Stress Response and
Molecular Chaperones , May 4, 2002, Cold Spring Harbor, USA.
25. Fatema K, Hannan JMA, Nurun Nabi AHM, Rahman MH, and Ali L. Effect of Sodium
cyclamate on serum lipids and platelet aggregation in nondiabetic rats. Diabetes Research and
Clinical Practice 2000;50 (suppl 1):S380
26. Faruque MO, Hannan JMA, Rahman MH, Nurun Nabi AHM, Rokeya B, Ali L, Mosihuzzaman
M, and Nahar N. Effect of tropical antihyperglycemic plant extract (M001) on plasma lipids and
platelet aggregation in type 2 model diabetic rats. Diabetes Research and Clinical Practice
2000;50 (1):S382
27. Rokeya B, Hannan JMA, Rahman MH, Nurun Nabi AHM, Ali L, Mosihuzzaman M, and Nahar
N. Chronic effect of cold aqueous extract of Allium sativum on glycemic and lipidemic status and
platelet aggregation in type 2 diabetic model rats. Diabetes Research and Clinical Practice 2000;
50 (1):S393
28. Rahman MH*, Fatema K, Parvin S, Hassan Z, Ahmed S, Mondal HN and Ali L. Glycemic and
insulinemic index of mango and papaya in type 2 diabetic subjects. The 35th Annual Meeting of
the EASD, September 28-October 2, 1999, Brussels, Belgium.
29. Zinnat R, Rahman MH, Mahmud I, Azad Khan AK, and Ali L. Role of serum glucose and
insulin in the pathogenesis of platelet hyperaggregation in diabetic subjects. The 35th Annual
Meeting of the EASD, September 28-October 2, 1999, Brussels, Belgium.
30. Rahman MH*, Zinnat R, Mahmud I and Ali L. Pathogenesis of platelet hyperaggregability in
diabetes mellitus. The 4th Diabetes and Endocrine Conference, December 12-13, 1998, Dhaka,
Bangladesh.

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* Attended and presented oral /poster presentation

PROFESSIONAL AFFILIATION
1. Member, European Association for the Study of Diabetes (EASD 990557).
2. Member, Japanese Universities Alumni Association in Bangladesh (JUAAB).
3. Member, Graduate Biochemist Association, Bangladesh (01L/94).
4. Member, Diabetes and Endocrine Society of Bangladesh.
5. Member, Asian Network of Research on Anti-diabetic Plants (ANRAP).
6. Core Member, Kumamoto International Education Progress (KIEP), Rangpur, Bangladesh.
PERSONAL INFORMATION:
Date of birth
Nationality
Passport No
Marital status

:
:
:
:

January 02, 1974

Bangladeshi
R 0753283
Married (one child)

Permanent address
Elephant Park # 5C
135 Elephant Road
Dhaka 1205
BANGLADESH
Phone: +880-2-9667966
REFEREES
Professor Dr. M. Iqbal Choudhary H.I., S.I., T.I.
Director
International Center for Chemical and Biological Sciences
University of Karachi, Karachi-75270, Pakistan
Phone: 021-34824934-6
Fax: 021-34819018-9
Email: hej@cyber.net.pk
Masataka Mori M.D., Ph.D.
Professor, Molecular Genetics
Faculty of Pharmaceutical Sciences
Sojo University
Kumamoto 860-0082, Japan
Phone: +81-96-326-4283
Fax: +81-96-326-5048
Email: mori-m@ph.sojo-u.ac.jp
Professor Liaquat Ali M.B.B.S, M.Phil., Ph.D.
Director, Bangladesh Institute of Health Sciences (BIHS)
Coordinator, Biomedical Research Group
Bangladesh Institute of Research and Rehabilitation in Diabetes,
Endocrine and Metabolic Disorders (BIRDEM)
Dhaka 1000, Bangladesh
Phone: +880-2-8617130, 8611138

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Email: lali@dab-bd.org

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