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What is cirrhosis?
Cirrhosis is a condition in which the liver
slowly deteriorates and is unable to function
normally due to chronic, or long lasting,
injury. Scar tissue replaces healthy liver
tissue and partially blocks the flow of blood
through the liver.
The liver is the bodys largest internal organ.
The liver is called the bodys metabolic
factory because of the important role it
plays in metabolismthe way cells change
food into energy after food is digested and
absorbed into the blood. The liver has many
functions, including
Liver
Bile ducts
Gallbladder
Small
intestine
Pancreas
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weakness
itching
loss of appetite
weight loss
nausea
bloating of the abdomen from
ascitesa buildup of fluid in the
abdomen
edemaswelling due to a buildup of
fluidin the feet, ankles, or legs
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a physical exam
a blood test
imaging tests
a liver biopsy
Medical and family history. Taking a medical
and family history is one of the first things a
health care provider may do to help diagnose
cirrhosis. He or she will ask the patient to
provide a medical and family history.
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Liver
A liver biopsy is a procedure that involves taking a piece of liver tissue for examination with a microscope for
signs of damage or disease.
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Preventing Problems
withMedications
People with cirrhosis should be careful
about starting new medications and should
consult a health care provider before taking
prescription medications, over-the-counter
medications, or vitamins. People with
cirrhosis should avoid complementary and
alternative medications, such as herbs.
Cirrhosis slows the livers ability to filter
medications from the blood. When this
slowdown occurs, medications act longer
than expected and build up in the body.
Some medications and vitamins may also
affect liver function.
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Points to Remember
Cirrhosis is a condition in which
the liver slowly deteriorates and is
unable to function normally due to
chronic, or long lasting, injury. Scar
tissue replaces healthy liver tissue
and partially blocks the flow of blood
through the liver.
The most common causes of cirrhosis
in the United States are chronic
hepatitis C, alcohol-related liver
disease, nonalcoholic fatty liver
disease (NAFLD) and nonalcoholic
steatohepatitis (NASH), and chronic
hepatitis B.
Many people with cirrhosis have no
symptoms in the early stages of the
disease. However, as the disease
progresses, a person may experience
the following symptoms:
a physical exam
weakness
a blood test
itching
imaging tests
loss of appetite
a liver biopsy
weight loss
nausea
bloating of the abdomen from
ascitesa buildup of fluid in the
abdomen
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References
1. Murphy SL, Xu J, Kochanek KD. Deaths:
final data for 2010. Centers for Disease
Control and Prevention website. www.
cdc.gov/nchs/data/nvsr/nvsr61/nvsr61_04.
pdf. Updated May 8, 2013. Accessed
February 6, 2014.
2. Wolf DC. Cirrhosis. Medscape website.
http://emedicine.medscape.com/
article/185856-overview. Updated August
5, 2013. Accessed February 6, 2014.
3. OShea RS, Dasarathy S, McCullough
AJ. Alcoholic liver disease. Hepatology.
2010;51(1):307328.
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Acknowledgments
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