Documente Academic
Documente Profesional
Documente Cultură
Yamanashi Prefecture
Tsuru High School
Brussels, Belgium
12h
Flandria,
Dutch speaking.
German speaking.
Brussels,
bilingual.
Wallonia,
French speaking.
Grand-Place,
Brussels.
Atomium, Brussels.
Famous places
EU Parlement,
Brussels.
The Lion , Waterloo.
Mannekenpis,
Brussels.
Onze Lieve Vrouw,
Antwerp.
Bruegel
1525-1569
Magritte
1896-1967
Famous painters
Delvaux
1897-1994
Carnival, Binche.
Flowers drawing,
Grand-Place, Brussels.
Famous Events
Le Doudou, Mons.
Belgian Beers
Belgian Chocolates
Famous Food
Belgian Waffels
Mussels and
Potato Fries
David LEMIN
Born in 1975, Uccle, Brussels, Belgium.
High School Graduation, Sciences oriented, 1994.
Graduate Diploma in Chemical Sciences, Free University of Brussels, 1998.
Master Degree in Scicences , Free University of Brussels, 2001.
PhD. In Sciences , Free University of Brussels, 2004.
Japan Society for the Promotion of Sciences, Post-Doctoral Fellowship,
Chiba University, Octobre 2004 - Octobre 2006.
Carbohydrates
A broad category of chemical compounds, also reffered as Sugars. The most abundant
class of bio-organic molecules on Earth. Although relatively low in human, it constitute
about 75% by mass of dry plant materials.
Main functions: Energy storage, structure element , source of carbon of the biosynthesis of other subtsances, Markers on cell surface for cell-cell recognition.
OH
OH
OH
HO
O OH
O OH
OH
OH
OO
OH
OH
HO
OH
OH
Lactose
Glucose
Lipids
A broad category of chemical compounds, also reffered as Fat. Most of those products
are non polar fat, oil, or wax that does not (or poorly) dissolves in water.
Main functions: Main componant of cells membrane, energy storage, communication
between cells (hormones).
O
O O
O O
O O
O
Triglyceride
(+)
O
P O
O (-)
OH
P hos phatidylcho line
O
Testosterone
Proteins
A broad category of chemical compounds composed of amino acids. Includins
Aminoacids, polypetides, Enzymes.
Main functions: Very large variety of functions, from maintenance or repairing of
existing tissues and synthesis of new ones to the catalysis of all the bio-chemical
reactions that take place in a living organism (Enzyms).
O
H 2N
OH
R
R =
R =
R =
R =
....
....
....
...
Secondary Structure
C H2S H : C ys
C H3 : A la
C H2C O O H : A sp
(C H2) 4N H 2 : L ys
Tertiary Structure
A m ino A cid s
Quaternary Structure
Primary Structure
Nucleic Acids
A category of complex chemical compounds involved in the transmition of genetic
information (DNA) and its transfert as information to the cell (RNA).
Sugar:
Ribose (RNA),
Desoxyribose (DNA)
Phosphate group
NH2
N
O
(-) O
P O P
P
O
O
(-) O
(-) O
(-) O
ATP
O
O
HO
OH
Metabolism
The Metabolism is the sum of all the chemical reactions that take place in a
living organism.
Primary Metabolism: All the chemical reactions necessary for the live of the
organism by itself.
Primary Metabolites: All the chemical products involved in the Primary
Metabolism.
Secondary Metabolites: All the chemical products that are produced by the
living organism but are NOT involved in the primary metabolism. Not necessary
for the live of the organism by itself but usefull for interaction with others
(chemical communication, chemical defences).
Tobacco Plant
N
CH3
N
Nicotine
N
CH3
N
Nicotine
N
CH3
N
Nicotine
Nest
O
N
H
Food
D is p a r lu r e
Reproduction
(-)
(+)
Coccinelline
sm
i
t
ma
se
o
p
2 H 2O 2
Enzyme
2 H2O + O2
+ HEAT
hydrogen peroxide
OH
O
Enzyme
+ 2 H2O
+ H2 O 2
OH
hydroquinone
O
p-benzoquinone
+ HEAT
OH
O O
HO
O O
Digitoxin
HO
O O
HO
OH
Digitalis purpurea
OH
Willow tree
OH
HO
OH
Salicin
O
OH
HO
Felix Hoffmann
1868-1946
Salicylic acid
O
Ac2O
OH
Aspirin
OH
NH
HO
OH
O
H
HO
OH
1 0 - d e a c e t y lb a c c a t in I I I
H
HO
T a xo l
O
O
HN
HO
O
N
Quinine
Cl
N
Chloroquine
N
H
N
CF 3 Mefloquine
Sedum acre
O
OH
O
N
CH3
CH3
h o m o s e d in o n e
OH
OH
CH3
R
OH
N
CH3
(-) O
P O P
P
O
O
O
(-)
(-) O (-) O
(+)
4Na
HO
OH
ATP
NH2
N
O
(-) O
P X P
P
O
O
O
(-)
(-) O
(-) O
(+)
4Na
X = -CH 2-, -CCl 2R=
O H
O
R
O
Chirality
Racemic mixture
(R )-L im o n e n e
s m e lls o r a n g e s
(S )-L im o n e n e
s m e lls le m o n s
One enantiomer
O
NH2
O
O
H2N
O
N
NH
O
Mitomycin C
Br
(-)
(+)
N
Ph
Ar
CHO
Ph
CO2tBu
N
N
Ar
Streptomyces
CO2tBu
one enantiomer
Acknolegments