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1/26/2016

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EYE
SWTEYE
Marking:+1MarksforcorrectanswerandnonegativeMarkingforincorrectanswer.
TestDuration(mins):120
TimeLeft(mins):120
Instructions
Oncethetesthasstarted,donotpresstherefreshbutton(orF5onyourkeyboard)
Itisadvisabletosavethetestregularlytoavoidlosingyourinformation,savetestreferstostoringtheattemptedpartofthetest.
Incaseofaccidentalfailureofinternetconnectivitythesystemwillsavetheattemptedportionofthetestautomatically.
Oncethetesttimeisover,youwillbeawardedagracedurationtowrapupthetestand"Submit"it.
Submittestreferstothefinalcompletionoftest;onceyousubmitthetestyouwillnotbeabletoedit/previewyouranswers.
Pleaseensurethatyouareconnectedtotheinternet,whilesubmittingthetest.

SWTEYE
(Q.1) OCT(Opticalcoherencetomography)isbasedon?
(a)
Highcoherenceinterferometry
(b)
Lowcoherenceinterferometry
(c)
Noncoherenceinterferometry
(d)
Polarization
YourResponse:
b
CorrectAnswer:
Exp:

OpticalCoherenceTomography(OCT)ISanewimagingmodalitythatproduceshighresolution,cross
sectionalimagesofocularstructuresinvivo.
OCTproducesdetailedtwodimensionalimagesoftheretinaandmeasuresretinalthicknesswitha
longitudinalimageresolutionofapproximately10microns.
TheprinciplesofOCTaresimilartoBmodeultrasound,howeverOCTutiIizesthereflectionofIightwaves
fromdifferentstructuresintheeyeratherthansound.
Lowcoherentlight,producedbyacontinouswavesuperluminescentdiodesource,isdirectedintotheeye
andisreflectedattheboundariesoftissueswithdifferentopticalproperties.

(Q.2) Redgreencolordefectmaybeseeninfollowingconditionsexcept:
(a)
Opticneuritis
(b)
Conedystrophy
(c)
Choroidaldetachment
(d)
Stargardt'sdisease.
YourResponse:
c
CorrectAnswer:
Exp:

Deuteranopiareferstoabsentofthemiddlewavelengthi.e.greencone.
Bluepigmentgeneisfoundonchromosome7whereasredandgreenpigmentgeneon
chromosomeX.
Redgreendefectisseeninacquiredopticnervedisease,conedystrophyandStargardt'sdisease.
Blueyellowdefectsinmostretinaldystrophy.Blueyellowdefectinglaucomaandautosomal
dominantopticneuropathy.

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(Q.3) Mostcommontypeoflidcarcinomais:
(a)
(b)
(c)
(d)
YourResponse:
CorrectAnswer:
Exp:

Squamouscell
Basalcell
Adenocarcinoma
Melanoma
c
Themostcommonmalignantepithelialgrowthoflidisbasalcellcarcinoma(rodentulcer).Itfrequently
arisesfromthelowereyelid,followedinrelativefrequencybythemedialcanthus

(Q.4) Aadvantageofindirectophthalmoscopeoverdirectophthalmoscopeinclude:
(a)
Binocularview
(b)
Highermagnification
(c)
Erectimage
(d)
Theinstrumentissmallersize
YourResponse:
a
CorrectAnswer:
Exp:

Directophthalmoscopehasthefollowingadvantagesoverindirectophthalmoscope:easilyportable,virtual
anderectimageandlargermagnification(15X).
Ontheotherhand,indirectophthalmoscopehasthefollowingadvantages:binocularity,higherfieldofview
andthepresenceofteachingmirror.

(Q.5) Inwhichofthefollowingcondition,Christmastreecataractisseen:
(a)
Myotonicdystrophy
(b)
Trauma
(c)
Diabetes
(d)
Wilsondisease
YourResponse
:
Correct
a
Answer:
Exp:

Inmyotonicdystrophy,posteriorsubcapsularstellateopacities
(Christmastreecataract).

(Q.6) Whichofthefollowingiscommonestmalignancycausingbilateralproptosisinpediatricpopulation?
(a)
Retinoblastoma
(b)
BilateralRhabdomyosarcoma
(c)
ALL
(d)
AML
YourResponse:
d
CorrectAnswer:
Exp:

ThecommoncausesofbilateralproptosisincludegranulocyticsarcomaduetoAML/Myelodysplastic
syndromeandmetastaticneuroblastoma.

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Rhabdomyosarcomaandretinoblastomararelyproducebilateralproptosis.
Themostcommonmalignancycausingunilateralproptosisinchildren:
InIndiaRetinoblastoma
InWesternpopulationRhabdomysarcoma
ThemostcommonprimaryorbitalmalignancyinchildrenRhabdomyosarcoma
ThemostcommonmetastaticorbitalmalignancyinchildrenNeuroblastoma

(Q.7) Whatisthediagnosis?

(a)

(b)

(c)

(d)

YourResponse:
CorrectAnswer:
Exp:

Epicanthus
Microblepharon
Cryptophthalmos
Colobomaofthelid
a
Thisisasemilunarfoldofskin,situatedaboveandsometimescoveringtheinnercanthus.
Itisusuallybilateralandgivestheappearancethattheeyesarefarapartandhaveaconvergentsquintand
thebridgeofthenoseisflat.
Itmaydisappearasthenosedevelops.Itisnormalinmongolianraces,anddeformitycanberemediedby
plasticsurgery.

(Q.8) Inwhichofthefollowingcondition,bandshapedkeratopathyisseen:
(a)
Angularconjunctivitis
(b)
Eales'disease
(c)
VitaminDpoisoning
(d)
Keratoconus
YourResponse:
CorrectAnswer: c
Exp:

Bandshapedkeratopathyisacommonconditioninold,blindandshrunkeneyesandin
Stillsdiseaseofchildren.
Sometimesitisassociatedwithhyperparathyroidism,vitaminDpoisoningandsarcoidosis.
Itispresentintheinterpalpebralareaformingacontinuousbandacrossthecornea.

(Q.9) Thefollowingtestsareusedintestingthevisionofpreverbalchildrenexcept:
(a)
(b)
(c)

LogMAR
STYCAR
Catforddrum

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(d)

SheridanGardinertests

YourResponse:
CorrectAnswer:
Exp:

a
FarnsworthMunsellhue100testcontains84colourdiscstobearrangedinorderofclosest
colourmatch.
Thecoloursonlydifferinhuewithsamebrightnessandsaturation.
Ishiharatestplatesaremainlyforcongenitalredgreencolourdefect.
WavylinesareusedinIshiharaplatesforilliteratesorchildren.LanthonyNewColourTest
canbeusedinchildren.

(Q.10) Cornealhysteresisisstudiedusing:
(a)
GoldmannApplanationtonometry
(b)
Goldmannperimetry
(c)
Cornealtopography
(d)
DynamicContourTonometry
YourResponse:
d
CorrectAnswer:
Exp:

CornealhysteresisassessesthebiomechanicalstrengthofthecorneaandisassessedbyDynamic
ContourTonometry(DCT)

(Q.11) Trueaboutretinoblastoma?
(a) Asomaticmutationisdetectedinabout95%ofallpatientsofretinoblastoma
(b) Changesonchromosome11qhavebeenobservedingermcellmutations.
(c) 5060%casesareinheritedasanautosomaldominanttrait.
(d) AssociationwithconcomitantEwingssarcomaiswellknown.
YourResponse:
a
CorrectAnswer:
Exp:

Asomaticmutationisdetectedinabout95%ofallpatientsofRetinoblastoma.Intheotherpatients,itis
inheritedasanautosomaldominanttrait.
Changesonchromosome13qhavebeenobservedingermcellmutationsincasesofRetinoblastoma.
Retinoblastomasmaythenoccuratseverallocationsintheretinaorbilaterally.Whereretinoblastomais
inheritedasanautosomaldominanttrait.
Themostcommonsecondmalignancyinpatientswithretinoblastomaosteosarcoma.

(Q.12) Thedrugofchoiceofhypertensiveuveitisis
(a)

(b)

(c)

(d)

YourResponse:
CorrectAnswer:
Exp:

Phosphatidyliodine
Latanoprost
Phenylephrine
Pilocarpine
c
HypertensiveuveitisInacutephaseofthediseasepresenceofexudatesandinflammatorycellsintheAC
maycausecloggingoftrabecularmeshworkresultinginthedecreaseddrainageandthusariseinIOP
Latanoprost(0.0005%)syntheticdrugwhichisanesteranalogueofprostaglandinF2alpha,itisonly

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drugwhichexclusivelyactsbyincreasingvesperaloutflowandbycausingreductioninepiscleralvenous
pressure
Sideeffectsincludeconjunctivalhyperaemia,foreignbodysensationandincreasedpigmentationofthe
iris
Dipivefrin(propineorDIphenylephrine)sympathomimeticdrugs(Adrenergicdrugs)
Mechanismofaction
Increaseaqueousoutflowresultsbyvirtueofbothalphaandbetareceptorstimulation
Decreasedaqueoushumourproductionoccursduetostimulationofalphareceptorsintheciliarybody
Sideeffectssystemicincludeshypertension,tachycardiaheadache,palpitation,tremors,nervousness
andanxiety

(Q.13) Thefollowinginstrumentisusedforwhichofthefollowing?

Fundusexamination

(a)

(b)

(c)

(d)

YourResponse:
CorrectAnswer:

Binocularvision
Colorvision
Farvision
b

Exp:

Thisopticalinstrumentiscalledassynoptophorewhichisusedfortheexaminationofbinocularvision,the
capacityforfusionandthemusclebalance.

(Q.14) Zieglerknifeisusedforwhichsurgery?
(a)
(b)
(c)
(d)
YourResponse:
CorrectAnswer:
Exp:

Cataract
Glaucoma
Lidsurgery
Noneoftheabove
d
(Ref:Parson,20thedition,Page269)
Itisusedtomanageposteriorcapsularopacification(PCO)inchildrenwhocannotbemanagedwith
Nd:YAGcapsulotomy.Aninstrumentusedforcuttingtheopacifiedposteriorcapsuleofthelensoftheeye
beforeaspiratingit.

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(Q.15) FollowingarefeaturesofOculomotornervepalsyexcept:
(a)

(b)

(c)

(d)

YourResponse:
CorrectAnswer:
Exp:

Diplopia
Ptosis
Miosis
Lateraldeviationofeye.
c
Thethirdnerveisamidlinestructurethatcontainsbothsympatheticmotorandvisceralnuclei.
Itinnervatestheipsilateralmedialrectus,inferiorrectus,andinferiorobliquemusclesaswellasthe
contralateralsuperiorrectusmuscle.
Acentralnucleusinnervatesbothlevatorpalpebraesuperiorismuscles.
Moreover,axonsfromvisceralnucleiprojectipsilateralparasympatheticoutflowtothepupillarysphincter
andciliaryganglion,whichcontrolpupillaryreflexesaswellasaccommodation.
Therefore,amidbraininfarction(involvingthenucleusoftheoculomotornerve),ifcomplete,willproduce
aunilateralthirdnervepalsycharacterizedbyipsilateralptosisandinabilitytoturntheeyeupward,
downward,andinward.Bilateralptosisandparalysisofthecontralateralsuperiorrectusmusclewillresult.
Pupillaryinvolvementwillalsobecomplete(dilatedpupil).Moredistallesionscanproducesingleor
multipleextraocularmuscleabnormalitieswithorwithoutpupillaryderangement.
Itisalsoimportanttorecognizethatthethirdnervemaybeimpingedalongitsextracranialextent.

(Q.16) Retinoblastomadiffersfrompseudogliomainthatitcauses
(a)
Decreasedintraocularpressure
(b)
Blurringofvision
(c)
Enlargementoftheopticforamen
(d)
Alloftheabove
YourResponse:
c
CorrectAnswer:
Exp:

(pseudogliomaisaTermgiventotheD/Dofleucocoria)
Increasedintraocularpressureisseeninretinoblastoma(andsocausesenlargementofopticforamen)
whereasloweredintraocularpressureiscommoninpseudoglioma
Calcificationsoccursin75%ofcasesandisalmostpathognomicofretinoblastoma
Bscanultrasounddisplaysacauliflowerlikemassesarisingfromretinawithorwithoutaretinal
detachmentorvitreoushemorrhage
Pseudogliomahaveaverydifferentultrasonographicpicture
Ifthelacticdehydrogenaseactivityisraisedintheaqueousrelativetotheserumlevel,itissuggestiveof
Retinoblastoma.
Retinoblastomabeingamalignanttumor,causeserosionandenlargementopticalformen

(Q.17) Choroidalneovascularizationcanbeseeninallthefollowingexcept:
(a)

(b)

(c)

(d)

YourResponse:
CorrectAnswer:

Hypermetropia
Angioidstreak
Trauma
Myopia
a

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Exp:

(Ref.Basaksophathalmology2nded.pg.162)
Choroidalneovascularization
Astheouterlayersoftheretinareceivenourishmentfromchoriocapillaris,degenerationofchoroidis
oftenassociatedwithatrophyofretina.
Secondarydegenerationsoccurfollowinginflammatorylesions,trauma,myopia,orinlatestagesof
glaucoma.
AngioidstreaksaremostcommonlyseeninPseudoxanthomaelasticum.
TheycanalsobeseeninPagetsdisease,EhlersDanlossyndrome,sicklecelldisease,andrarelyin
acromegaly,hypercalcemia,andleadpoisoning.
Angioidstreakmaycausevisualimpairmentduetoinvolvementoffovea,choroidalneovascularizationor
choroidalrupture.

(Q.18) AssessmentandaidingfordevelopmentoffundsfortheNationalBlindnessControlProgrammeisdoneby:
(a)
(b)
(c)
(d)
YourResponse:
CorrectAnswer:
Exp:

UNICEF
WorldBank
DANIDA
WHO

b
(Ref.ParksTextbookofPSMbyK.Park21steditionpageNo.401)
FundingfortheNPCB
TheallocationoffundsfortheNPCBincreasedwiththestartoftheWorldBankfinancedProjectin1995.
ThetotaloutlayfortheNPCBintheNinthFiveYearPlanwasRs480crore.In200102,theoutlaywasRs
127.57crore,ofwhichthemajorcontributioncamefromtheWorldBank(75.7%)and16.4%fromthe
GovernmentofIndia.
AftertheendoftheWorldBankfinancedProjectin200102,theNPCBisbeingsustainedmainlythrough
thedomesticbudgetforwhichanallocationofRs445crorehasbeenmadeintheTenthFiveYearPlan.
TheGovernmentofIndiacontributed84.6%oftheRs85.59crorefortheProgrammein200203and
90.5%oftheRs86.96crorein200304;theremainingfundscomefromDanishassistance.
Themajorpartofthefundingwenttothedistricts(87.52%),therebyindicatingthatalargequantumof
theearmarkedfundsgodirectlyforpatientcare.OfthefundsutilizedattheCentralandStatelevels,the
majorpartisspentoninformation,educationandcommunication(IEC)activities,training,review,
monitoringandevaluation.

(Q.19) AboutBestdisease,falseis?
(a) Itisarecessivegeneticdisorder
(b) Sunnysideupeggyolk"ischaracteristicfeature
(c)
ERGisnormal,butanabnormalEOGishallmarkofthisdisease
(d) ThereisnosatisfactorytreatmentavailableforBest'sdisease.
YourResponse:
a
CorrectAnswer:
Exp:

Best'sdisease,alsocalledVitelliformmaculardystrophy,isanautosomaldominant(i.e.,50%offamily
membershaveit)formofgeneralizedretinalpigmentepithelium(RPE)dystrophy.T
heRPEisalayerofcellsinthebackoftheeyethatprovidesnourishmenttotheretinaand
photoreceptors.
Clinically,Best'sdiseaseischaracterizedbyoneormorelesionsinthebackoftheeyethatsometimes

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takesontheappearanceofa"sunnysideupeggyolk"intheearlystagesofthediseaseandlaterappears
asa"scrambledegg."
Dependingonthelocusofthelesion(s)itmayormaynotaffectvision.
Ifitdoesnotaffectvision,thenthepatientisanasymptomaticcarrierofthedisease.
Whenitdoesaffectvision,visualacuitymayrangefrom20/30to20/200(legalblindness).
ThereisnotreatmentavailableforBest'sdisease.ThediagnostictestforBest'sdiseaseistheelectro
oculogram(EOG),Visualacuityoftenremainsgood,andtheergisnormal.
Anabnormalelectrooculogram(EOG)isthehallmarkofthedisease.

(Q.20) Falseregardingfungalcornealulcer?
(a)
Signsaremorepronouncedascomparedtosymptoms
(b)
Satellitelesionsareseen
(c)
Topicalsteroidsmaybeused
(d)
Perforationisrare
YourResponse:
c
CorrectAnswer:
Exp:

Injurybyvegetativemattercausesfungalulcer.TypicallySymptoms<signs.
DrylookingulcerwithfeatheryextensionsandImmunering(Wesleysring).
Satellitelesionsmayoccur.Hypopyonisfixed.Perforationisrare.Nocornealvascularization.
Steroidsarecontraindicated.

(Q.21) Theonsetofpresbyopiadependsonthefollowingfactorsexcept:
(a)
Thesizeofthepupil
(b)
Sexofthepatient
(c)
Therefractivestateofthepatient
(d)
Amplitudeofaccommodation
YourResponse:
b
CorrectAnswer:
Exp:

Presbyopiaistheagerelatedlossoftheabilitytocomfortablysustaintheaccommodationnecessaryfor
clearnearvision.
Itsonsetisdependenton:theamplitudeofaccommodationtaskrequiredrefractivestateofthepatients
(earlierwithhypermetropiathanmyopia)sizeofthepupil(smallpupilhasapinholeeffect)latitudewhere
patientlives(onsetisearlierinthetropicthantemperatecountries)

(Q.22) Superonasalavulsionofthevitreousbaseispathognomonicof:
(a)
Traumaticretinaldetachment.
(b)
Earlyacutevitreoushemorrhage
(c)
Vitreoretinalmembrane
(d)
Rhegmatogenousretinaldetachment
YourResponse:
a
CorrectAnswer:
Exp:

Vitreousbaseavulsionispathognomonicforbluntoculartrauma.
Thevitreousbaseisfirmlyattachedtotheperipheralneurosensoryretinaaswellastothenonpigmented
epitheliumoftheparsplana.
Incasesofsubstantialblunttraumatotheglobe,avulsionoftheVitreousBaseoccurs.Itistypicallylocated

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intheinferotemporalorsuperotemporalquadrants.

(Q.23) Sphericalaberrationinhumaneyeisreducedbywhichofthefollowing?
(a) Theanteriorsurfaceofthecorneaisflatterperipherallythancentrally
(b) Thecortexofthelenshasahigherrefractiveindexthanthenucleus
(c) Thelenshasvariableanteriorsurfacecurvature
(d) Theretinahasaradiusofcurvaturewhichisshortercentrallythanperipherally
YourResponse:
CorrectAnswer: a
Exp:

Thefollowinginhumaneyereducessphericalaberration:
Theanteriorsurfaceofthecorneaisflatterperipherallythancentrally.
Thenucleusofthelensoftheeyehasahigherrefractiveindexthanthelenscortex.
Thepresenceofirisreduceslightcomingfromtheperipherallens.
Theretinalconesaremoresensitivetolightenteringtheeyeparaxiallythantolight
enteringobliquely.

(Q.24) Duaslayerislocated:
(a)
BetweenthecornealstromaandDescemet'smembrane
(b)
BetweentheendotheliumandDescemet'smembrane
(c)
Posteriortotheendothelium
(d)
BetweenepitheliumandBowmanslayer
YourResponse:
a
CorrectAnswer:
Exp:

Dua'slayer,accordingtoa2013paperbyHarminderSinghDua'sgroupattheUniversityofNottingham,is
alayerofthecorneathatis15micronsthickandlocatedbetweenthecornealstromaandDescemet's
membrane.

(Q.25) Allofthefollowingarenewstrategiesforcataractsurgeryexcept:
(a)
IOLimplantation.
(b)
Freeophthalmicservice.
(c)
Fixedfacilitysurgicalapproach.
(d)
Outreacheyecamps
YourResponse
:
CorrectAnswer d
:
Exp:

(Ref.BasakOphthalmology3rded.344)
"Revisedstrategyistoshiftfromtheeyecampapproachtoafixedfacility
surgicalapproach"

(Q.26) Visiblespectrumoflightinhuman:
(a)
(b)
(c)

200280nm
280315nm
315400nm

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(d)

400700nm

YourResponse:
CorrectAnswer:

Exp:

(Ref.GuytonPhysiology11th/pg.631;Figure507)
Theeyesconvertenergyinthevisiblespectrumintoactionpotentialsintheopticnerve.
Thewavelengthsofvisiblelightrangefromapproximately397nmto723nm.
Theimagesofobjectsintheenvironmentarefocusedontheretina.Thelightraysstrikingtheretina
generatepotentialsintherodsandcones.
Impulsesinitiatedintheretinaareconductedtothecerebralcortex,wheretheyproducethesensationof
vision.

(Q.27) Pterygiumischaracterizedby?
(a)
Excessivecollagendegenerationofthesubconjunctivaltissue
(b) Acuteinflammatoryreactionofthesubconjunctivaltissue
(c)
Pseudovascularizationofconjunctiva
(d) Conjunctivaltumor
YourResponse:
a
CorrectAnswer:
Exp:

(Ref.Basaksophathalmology2nded.pg.106)
PTERYGIUM
Pterygiumusuallyreferstoabenigngrowthofthesubconjunctivaltissue
Pterygiumintheconjunctivaischaracterizedbyelastoticdegenerationofcollagenandfibrovascular
proliferation.
Apterygiumcommonlygrowsfromthenasalsideofthesclera.
Itiscausedbyultravioletlightexposure(e.g.sunlight),lowhumidity,anddust.
Thepredominanceofpterygiaonthenasalsideispossiblyaresultofthesun'srayspassinglaterally
throughthecorneawhereitundergoesrefractionandbecomesfocusedonthelimbicarea.
Sunlightpassesunobstructedfromthelateralsideoftheeye,focusingonthemediallimbusafterpassing
throughthecornea.
Onthecontralateralside,however,theshadowofthenosemediallyreducestheintensityofsunlight
focusedonthelateral/temporallimbus.

(Q.28) Irispearlsareseeninuveitisof
(a)
(b)
(c)
(d)
YourResponse:
CorrectAnswer:
Exp:

Syphilis

Leprosy
Tuberculosis
Sarcoidosis
b
Alltheabovearecausesofgranulomatousuveitis.Leprosyleadstoonlyanterioruveitiswhileothersare
causesofpanuveitis.
Featuresofgranulomatousuveitisare
MuttonfatKPs
Broadbasedposteriorsynechiae&
Irisnodule(KoeppesonpupilandBusaccasonirissurface).Inleprosyirisnodulesarewhiteknownasiris

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pearls(pathognomonic).
BeadedCornealnervesareseeninleprosy.

(Q.29) Whichoffollowingisassociatedwithintensevitritis?
(a)
CMVretinitis
(b)
Acuteretinalnecrosis
(c)
Progressiveouternecrosis
(d)
HIVretinopathy
YourResponse:
b
CorrectAnswer:
Exp:

AllaremanifestationsofHIV/AIDSineye.CMVretinitisisseeninpatientswithCD4<50,hastypicalcheese
andketchupappearanceandistreatedwithgancyclovir.Thereismildmoderatevitritis.
ARN&PORNarecausedbyherpesandvaricellazoster.
Acuteretinalnecrosis(ARN)isaclinicalsyndromecharacterizedbyvitritis,severeocclusivevasculitis
whichproducesafullthickness,necrotizingretinitis.
Thediseaseiscausedbyanacuteinfectionwithamemberoftheherpesvirusfamily,usuallyVZVorHSV.
Theprognosisispoor,withsignificantvisualloss.
Clinicalcoursemostoftenleadstodetachmentoftheatrophicretina,regardlessantiviraltreatment.
HIVretinopathyiscausedbyHIVvirusitselfandisthemostcommoneyemanifestation.Itischaracterised
byCottonwoolspotsandhasnospecifictreatment.

(Q.30) WhichofthefollowingisnottrueaboutJackson'scrosscylinder?
(a) Doesnotblurtheimagewhenplacedbeforeanemmetropiceye
(b) Doesnotalterthesphericalequivalentofanametropiceye
(c) Isusedtochecktheaxisofthecylindersubjectively
(d) Isusedtocheckthepowerofthecylindersubjectively
YourResponse:
a
CorrectAnswer:
Exp:

Crosscylinderexamination(otherwiseknownasJackson'scrosscylinder)isanexaminationusedforthe
finalfinetuningoftheaxisandstrengthofastigmatismafteritsdeterminationthroughretinoscopy,
stellatecycleorautomaticrefractometry.
Withtheadventoftechnology,techniqueslikeretinoscopyandcrosscylinderexaminationmightseem
outdatedandusefulonlytothepersonnelofhumanitarianmissions.
Theydohoweverprovideanaccuratealternativeandtheirusegivesathoroughunderstandingofthe
principlesofrefraction.
Placedbeforeanemmetropiceye,thecrosscylinderblurstheimage.Placedbeforeanametropiceye,the
crosscylinderdoesnotalterthesphericalequivalent,butitwillenlargeorcontracttheintervalofSturm,
blurringorclarifyingtheimage,asitincreasesordecreasesthenetastigmaticametropia.
Thecrosscylinderisusedforsubjectiverefinementofaxisandpowerofcylinderafterplacingthebest
availableestimateofrefractionbeforetheeye(retinoscopy,astigmaticdialtest,orpreviousrefraction).

(Q.31) Hereditarydiseasesassociatedwithretinitispigmentosaincludethefollowingexcept:
(a)

(b)

(c)

(d)

YourResponse:

EagleBardetsyndrome
BassenKornzweigdisease
KearnsSayresyndrome
Refsumsdisease

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CorrectAnswer:

Exp:

Retinitispigmentosamayoccurinassociationwithrare,hereditarysystemicdiseaseslike
olivopontocerebellardegeneration,BassenKornzweigdisease,KearnsSayresyndrome,Refsumsdisease.
Chronictreatmentwithchloroquine,hydroxychloroquine,andphenothiazines(especiallythioridazine)can
producevisuallossfromatoxicretinopathythatresemblesretinitispigmentosa.

(Q.32) Whichcranialnervepalsyproduceshorizontaldiplopia,worseongazetothesideofthelesion?
(a)

VI

(b)
(c)

IV

(d)
YourResponse:
CorrectAnswer:

II

III

Exp:

Thesixth(abducens)cranialnerveinnervatesthelateralrectusmuscle.Apalsyproduceshorizontal
diplopia,worseongazetothesideofthelesion.
Anuclearlesionhasdifferentconsequences,becausetheabducensnucleuscontainsinterneuronsthat
projectviathemediallongitudinalfasciculustothemedialrectussubnucleusofthecontralateral
oculomotorcomplex.
Therefore,anabducensnuclearlesionproducescompletelateralgazepalsy,fromweaknessofboththe
ipsilaterallateralrectusandthecontralateralmedialrectus.

(Q.33) Radiusofcurvature(mm)ofanteriorsurfaceof
cornea?

8.4

(c)

(d)

Your
Response
:
Correct b
Answer:

5.8

(a)
(b)

Exp:

7.8
4.8

(Ref.GuytonPhysiology11th/pg.617)
TheCornea
RefractiveIndex:1.3
Posterior(back)Surface
Distancealongaxisfromcornealpole:.55
mm
Anterior(front)Surface
Radiusofcurvature:7.8mm
Posteriorcornealsurface:6.5mm

(Q.34) TrueaboutIridocornealEndothelialSyndrome?
(a)
(b)

Neovascularizationofiris
Progressivediffuseirisatrophy

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(c)

Diffusebilateralsenileirisdegeneration

(d) DepositionofacidmucopolysaccharidesinDescemetsmembrane
YourResponse:
b
CorrectAnswer:
Exp:

(Ref.Basaksophthalmology2nded.pg.161)
IRIDOCORNEALENDOTHELIALSYNDROME
Unknownetiology.
Characterizedby
i.Glaucoma,ii.Irisatrophy,iii.Decreasedendothelium,andiv.Irisnodules.
Aftermetaplasia,thecornealendotheliumproliferates,andDescemetsmembranelikematerialcovers
theanteriorsurfaceandangleoftheanteriorchamber,causingirisanomaliesandsecondaryglaucoma.
Thespectrumincludes3conditions:
i.Progressiveessentialirisatrophyii.Chandlerssyndromeiii.Irisnaevussybdrome

(Q.35) Thefollowingistrueforaccommodationexcept:
(a) Thefarpointofdistinctvisionofanemmetropiceyeisatinfinity
(b) Rangeofaccommodationisthedifferenceindioptricpowerbetweentheeyeatrestandfullyaccommodatedeye
(c) Dynamicrefractionreferstothedioptricpoweroftheaccommodatedeye
(d) Staticrefractionreferstothedioptricpowerofarestingeye
YourResponse:
b
CorrectAnswer:
Exp:

Rangeofaccommodationreferstothedistancebetweenthefarpointandthenearpoint.Thedifference
indioptricpowerbetweentheeyesatrestandthefullyaccommodatedeyeiscalledtheamplitudeof
accommodation.

(Q.36) Snowbankingisseenin:
(a)

Parsplanitis

(b)
(c)

Endophthalmitis
Ealesdisease

(d)
Coatsdisease
Your
Response
:
Correct a
Answer:
Exp:

(Ref.Parsonsdiseaseofeye19th
ed.360)
Snowbankingisseeninpars
planitis.

(Q.37) CausativefactorforMaculardegenerationindiabetesmellitus?
(a)

Retinalischemia

(b)
(c)

Neovascularization

(d)

Lipiddeposition

Hemorrhages

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YourResponse:
CorrectAnswer:
Exp:

a
(Ref.Basaksophthalmology2nded.pg.16,299,300)
BlindnessinDMisprimarilytheresultofprogressivediabeticretinopathyandclinicallysignificantmacular
edema.
Diabeticretinopathyisclassifiedintotwostages:
nonproliferativeand
proliferative.
Nonproliferativediabeticretinopathyusuallyappearslateinthefirstdecadeorearlyintheseconddecade
ofthediseaseandismarkedbyretinalvascularmicroaneurysms,blothemorrhages,andcottonwool
spots.Mildnonproliferativeretinopathyprogressestomoreextensivedisease,characterizedbychangesin
venousvesselcaliber,intraretinalmicrovascularabnormalities,andmorenumerousmicroaneurysmsand
hemorrhages.Thepathophysiologicmechanismsinvokedinnonproliferativeretinopathyincludelossof
retinalpericytes,increasedretinalvascularpermeability,alterationsinretinalbloodflow,andabnormal
retinalmicrovasculature,allofwhichleadtoretinalischemia.

(Q.38) Chalazionis?
(a)

Lipogranuloma

(b)
(c)

Acutebacterialinfection
InfectionoftheglandsofZeisorMoll

(d)
Stye
YourResponse:
CorrectAnswer:
Exp:

a
(Ref.ParsonsdiseasesofEye19thed.467)
Chalazionisachronicnonspecific,noninflammatorygranulomaofMeibomianglandswithalipomatous
center.
ThelipidcomponentofthetearfilmisproducedbysebaceousglandsknownasMeibomianglands
(locatedinthetarsalplatesalongtheeyelidmargins)andtheglandsofZeis(whichopenintothehair
folliclesoftheeyelashes).
AnenlargementofaMeibomianglandisknownasachalazionorhordeoluminternumwhilean
infectionofaZeisglandisknownasahordeolumexternumorstye.
Belowthelipidlayerislocatedtheaqueouslayerofthetearfilm.
Thismiddlelayeristhethickestofthethreetearlayers,anditisformedprimarilybytheglandsof
KrauseandWolfringandsecondarilybythelacrimalgland,allofwhicharelocatedintheeyelids.

(Q.39) Tearbreakuptime(TBUT)is:
(a)

<4seconds

(b)
(c)

58seconds

(d)
YourResponse:
CorrectAnswer:

1012seconds

Exp:

IntestingforTearBreakUpTime,sodiumfluoresceindyeisaddedtotheeyeandthetearfilmisobserved
undertheslitlampwhilethepatientavoidsblinkinguntiltinydryspotsdevelop.Thelongerittakes,the
morestablethetearfilm.Ashorttearbreakuptimeisasignofapoortearfilm.

<10seconds

Generally,>10secondsisthoughttobenormal,5to10seconds,marginal,and<5secondslow(withhigh
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likelihoodofdryeyesymptoms).
Meibomiamglanddysfunction,wherenotenoughlipidissecretedbythemeibomianglandstosealthe
aqueoustearsandretardevaporation,isacommoncauseoftearfilminstability.

(Q.40) Thefollowingaretrueaboutmyopiaallexcept:
(a)
(b)

Thesecondprincipalfocusliesbehindtheretina
Thepresenceofposteriorstaphylomasuggestsaxialmyopia

(c)
Nucleosclerosisisacauseofindexmyopia
(d)
Highmyopiamaybetreatedwithclearlensextraction
YourResponse:
a
CorrectAnswer:
Exp:

Inmyopia,thesecondprincipalfocusliesinfrontoftheretina.
Myopiamaybeclassifiedintoaxialmyopia(inwhichtheeyeisabnormallylongasinhighmyopiawhich
canproducestaphyloma)orrefractiveorindexmyopiainwhichtherefractivepoweroftheeyeis
increasedasinkeratoconusandnuclearsclerosis.

(Q.41) Falseabouttheimageformedbyanindirectophthalmoscope:
(a)
(b)

Isupsidedown
Isreal

(c)
Islaterallyinverted
(d)
Isnotaffectedbytherefractivestateofthepatient
YourResponse:
d
CorrectAnswer:
Exp:

Theimageformedbytheindirectophthalmoscopeisrealandinverted(bothverticallyandlaterally).
Itissituatedbetweentheobserverandthecondensinglens.
Theimageformedisaffectedbytherefractivestateofthepatientbutnottothesameextentaswith
directophthalmoscope.

(Q.42) Thefollowingaretrueabouthypermetropiaallexcept:
(a) Almost10timesmorecommoninfemalesthaninmales.
(b) Accommodationisusedtoachievenormalvision
(c) Aphakiaisaformofhypermetropia
(d) Patientwhohashypermetropicrefractionfollowingcataractsurgerywillhaveproblemforbothnearanddistantreading.
YourResponse:
a
CorrectAnswer:
Exp:

Thesecondprincipalfocusofhypermetropialiesbehindtheretina.
Accommodationisusedtocorrecttheemmetropiatocertainextent.
Theyrequirereadingglassesearlierthanthenormalpopulation.
Aphakiaisaformofhypermetropia.Followingcataractsurgery,theaccommodativeabilityoftheeyeis
lost.
Therefore,ifthepatientishypermetropic,thevisionwillbeblurredfordistantandnear.
Thisisthereasonwhymostpatientsaremadeslightlymyopicsothattheycanachieveareasonablevision
withoutglassesfordistance.

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(Q.43) Inayoungpatientcomplainingofflashesofbrightlight,"aveilfallinginfrontoftheeye,"withpainlesslossofvision,themost
likelyclinicaldiagnosisis?

(a)

Retinaldetachment

(b)
(c)

Ealesdisease

(d)

YourResponse:
CorrectAnswer:

Macularhole

Exp:

Vitreoushemorrhage

a
Ifthepatientcomplainsofflashesofbrightlight,"acurtainfallinginfrontoftheeye,"orfloatingblack
specks,thesefindingsmaybeanindicationofretinaldetachment.
Aretinaldetachmentispainless.Peopleusuallyseeanincreaseinsmall,floatingobjects(floaters)ormany
flashesofbrightlightthatlastlessthanasecond.
Peripheralvisionistypicallylostfirst,andvisionlossspreadsasthedetachmentprogresses.
Thelossofvisionresemblesacurtainorveilfallingacrossthelineofsight.
Ifthemaculabecomesdetached,visionrapidlydeteriorates,andeverythingbecomesblurred.

(Q.44) Tonicpupilisleastlikelytobeseeninwhichofthefollowingcondition?
(a)

ShyDragersyndrome

(b)
(c)

Syphilis

(d)

YourResponse:
CorrectAnswer:
Exp:

Diabetes
Amyloidosis
b
Whenthenearstimulusisremoved,thepupilredilatesveryslowlycomparedwiththenormalpupil,
hencethetermtonicpupil.
InAdiessyndrome,atonicpupiloccursinconjunctionwithweakorabsenttendonreflexesinthelower
extremities.
Thisbenigndisorder,whichoccurspredominantlyinhealthyyoungwomen,isassumedtorepresenta
milddysautonomia.
TonicpupilsarealsoassociatedwithShyDragersyndrome,segmentalhypohidrosis,diabetes,and
amyloidosis.
Occasionally,atonicpupilisdiscoveredincidentallyinanotherwisecompletelynormal,asymptomatic
individual.
Thediagnosisisconfirmedbyplacingadropofdilute(0.125%)pilocarpineintoeacheye.

(Q.45) Whichofthefollowingisassociatedwithipsilateraloculomotorpalsywithcontralateralhemiparesis?
(a)
(b)

(c)

(d)

YourResponse:
CorrectAnswer:
Exp:

Nothnagelssyndrome
Benediktssyndrome
Weberssyndrome
Claudessyndrome
c
InNothnagelssyndrome,injurytothesuperiorcerebellarpedunclecausesipsilateraloculomotorpalsy
andcontralateralcerebellarataxia.
InBenediktssyndrome,injurytotherednucleusresultsinipsilateraloculomotorpalsyandcontralateral

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tremor,chorea,andathetosis.
Claudessyndromeincorporatesfeaturesofboththeaforementionedsyndromes,byinjurytoboththered
nucleusandthesuperiorcerebellarpeduncle.
InWeberssyndrome,injurytothecerebralpedunclecausesipsilateraloculomotorpalsywith
contralateralhemiparesis.

(Q.46) Inclusionconjunctivitisiscausedby?
(a)
(b)

Chlamydiapneumoniae

Chlamydiatrachomatis

(c)
Chlamydiapsittaci
(d)
L1,L2,L3serovars
YourResponse:
b
CorrectAnswer:
Exp:

Chlamydiae
Chlamydiaeareobligateintracellularparasitesthatcausemucosalinfections.
Thechlamydialpeptidoglycanwallisunusualinthatitlacksmuramicacid.
Its2formsare:
Elementarybody(small,dense),whichEnterscellviaendocytosis.
InitialorReticulatebody,whichReplicatesincellbyfission.
Chlamydiatrachomatiscausesreactivearthritis,inclusionconjunctivitis,andnongonococcalurethritis.
ChlamydiatrachomatisisinfactthemostcommoncauseofsexuallytransmitteddiseaseintheUnited
Statesandisalsoresponsibleforthemajorityofcasesofinfantconjunctivitisandinfantpneumonia.
LGVisasexuallytransmitteddiseasecausedbyC.trachomatisofimmunotypesL1,L2,andL3.
Labdiagnosis:cytoplasmicinclusionsseenonGiemsaorfluorescentantibodystainedsmear.
C.pneumoniaeandC.psittacicauseatypicalpneumonia;transmittedbyaerosol.
Treatment:erythromycinortetracycline.

(Q.47) Scleraisthinnestat:
(a)
(b)

Limbus
Equator

(c)
Anteriortoattachmentofsuperiorrectus
(d)
Posteriortoattachmentofsuperiorrectus
YourResponse:
d
CorrectAnswer:
Exp:

(Ref.Parsonssdiseasesofeye20thed.210)
Thescleravariesinthicknessbeingthickest(1mm)attheposteriorpole,neartheopticnerveandthinnest
(0.3mm)justbehindtheinsertionofrectusmuscles.

(Q.48) Apersonhasrestrictedeyemovementsinalldirections,ptosisbutnosquintordiplopia.Whatisthediagnosis?
(a)
(b)

Myasthenia
CPEO

(c)
Multiplecranialnervepalsy
(d)
Thyroidmyopathy
YourResponse:
b
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CorrectAnswer:
Exp:

(Ref.Harrison17th/2690;OphthalmologybyGerhardK.Langpg.486;Pocketatlasofophthalmology
pg.63)
Chronicprogressiveexternalophthalmoplegia(CPEO)
CPEOisamitochondriopathy.Thereisslowlyprogressiveweaknessofalltheocularmuscleswitha
variabledegreeofmotilitydisordersandcorrespondingdoublevision,andsubsequentlythereisalso
involvementofthelimbmuscles.
Bilateralptosiswithgreatlyimpairedlevatorfunctionisoftenobserved.
Inadditionthereisweaknessofthemusclesoffacialexpression,particularlytheorbicularisoculi.
AspecialformistheKearnsSayresyndrome.Alongwiththemuscleweakness,therearechangesinthe
funduslikethoseofretinitispigmentosaandalsocardiacarrhythmias,hearingdisorders,andmental
retardation.
CausaltreatmentofCPEOisnotpossible.

(Q.49) HornerssyndromeischaracterizedbythefollowingEXCEPT?
(a)
(b)

Ptosis

Miosis

(c)
Heterochromiairidis
(d)
Apparentexophthalmos
YourResponse:
d
CorrectAnswer:
Exp:

(Ref.VictorAdamsNeurology,pg296.)
Hornersyndromeischaracterizedby
a.Ptosisb.Miosisc.Anhydrosis,d.Enophthalmose.Lossofciliospinalrefles
CONGENITALHornersyndrome,whichmaybeinheritedasanautosomaldominanttrait,ischaracterized
byfailureofoneeyetodevelopnormaliriscolor(heterochromiairidis).

(Q.50) Mostisolatedtrochlearnervepalsiesaredueto?
(a)
(b)

(c)

(d)

YourResponse:
CorrectAnswer:
Exp:

Idiopathic
Closedheadinjuries
Aneurysmalrupture
Diabetesmellitus
a
Isolatedtrochlearnervepalsyoccursfromallthecauseslistedabovefortheoculomotornerve,except
aneurysm.
Thetrochlearnerveisparticularlyapttosufferinjuryafterclosedheadtrauma.
Thefreeedgeofthetentoriumisthoughttoimpingeuponthenerveduringaconcussiveblow.
Mostisolatedtrochlearnervepalsiesareidiopathicandhencediagnosedbyexclusionasmicrovascular.
Spontaneousimprovementoccursoveraperiodofmonthsinmostpatients.
Abasedownprism(convenientlyappliedtothepatientsglassesasastickonFresnellens)mayserveasa
temporarymeasuretoalleviatediplopia.
Ifthepalsydoesnotresolve,theeyescanberealignedbyweakeningtheinferiorobliquemuscle.

(Q.51) Blowoutfractureoforbitmostcommonlyleadstofractureof:
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(a)

Lateralwall

(b)

Roofoforbit

(c)
Medialwalloforbit
(d)
Posteriormedialwalloffloor
YourResponse:
d
CorrectAnswer:
Exp:

(Ref.OphthalmologyAShortTextbookGerhardK.Langpg.507)
BlowoutFracture
Etiology:
Blowoutfracturesoftheorbitresultfromblunttrauma.Bluntobjectsofsmalldiameter,suchasafist,
tennisball,orbaseball,cancompressthecontentsoftheorbitsoseverelythatorbitalwallfractures.This
fractureusuallyoccurswheretheboneisthinnest,alongthepaperthinflooroftheorbitoverthemaxillary
sinus.Theringshapedbonyorbitalrimusuallyremainsintact.Thefracturecanresultinprotrusionand
impingementoforbitalfatandtheinferiorrectusanditssheathsinthefracturegap.Wherethemedial
ethmoidwallfracturesinsteadoftheorbitalfloor,emphysemaintheeyelidswillresult.
Symptomsanddiagnosticconsiderations:
Themoreseverethecontusion,themoreseveretheintraocularinjuriesandresultingvisualimpairment
willbe.Impingementoftheinferiorrectuscanresultindiplopia,especiallyinupwardgaze.Initially,the
diplopiamaygounnoticedwhentheeyeisstillswollenshut.Alargebonedefectmayresultin
displacementoflargerportionsofthecontentsoftheorbitalcavity.Theeyemayrecedeintotheorbit
(enophthalmos)andthepalpebralfissuremaynarrow.Injurytotheinfraorbitalnerve,whichcourses
alongtheflooroftheorbit,mayresult.Thiscancausehypesthesiaoftheskinofthecheek.
Crepitusuponpalpationduringexaminationoftheeyelidswellingisasignofemphysemaduetocollapse
oftheethmoidalaircells.Thecrepitusiscausedbyairenteringtheorbitfromtheparanasalsinuses.The
patientshouldrefrainfromblowinghisorhernoseforthenextfourorfivedaystoavoidforcingairor
germsintotheorbit.

(Q.52) Neovascularglaucomaisnotseenin:
(a)

JRA

(b)
(c)

CRVO

(d)
YourResponse:
CorrectAnswer:

Eales'disease

Exp:

CRAO

a
Neovascularglaucoma(NVG)ischaracterizedbyformationofnewvesselsonthesurfaceofiris
(rubeosisiridis).andtrabecularmeshworkwhichleadstoraisedintraocularpressure.Itis
commonlycausedbyretinalischemiaduetothefollowingdiseases:
CRVO

Diabeticretinopathy

CRAO

Eales'disease

Longstandingretinal
detachment

Sicklecellretinopathy

Intraoculartumors
NVGoccursin510%ofCRAO.
InJRA,glaucomagenerallypresentsasacuteangleclosure,duetoposteriorsynechiae,orchronic
angleclosure,which
resultsfromprogressive,peripheralanteriorsynechiae.

(Q.53) Fortificationspectraarefeatureof?
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(a)

Maturecataract

(b)

Immaturecataract
AmaurosisFugax

(c)

(d)

YourResponse:
CorrectAnswer:

Migraine
d

Exp:

Inatypicalattack,asmallcentraldisturbanceinthefieldofvisionmarchestowardtheperiphery,leavinga
transientscotomainitswake.
Theexpandingborderofmigrainescotomahasascintillating,dancing,orzigzagedge,resemblingthe
bastionsofafortifiedcity,hencethetermfortificationspectra.
Patientsdescriptionsoffortificationspectravarywidelyandcanbeconfusedwithamaurosisfugax.
Migrainepatternsusuallylastlongerandareperceivedinbotheyes,whereasamaurosisfugaxisbriefer
andoccursinonlyoneeye.
Migrainephenomenaalsoremainvisibleinthedarkorwiththeeyesclosed

(Q.54) InERG'A'wavescorrespondsto:
(a)

Rodsandcones

(b)
(c)

Nervebundlelayer

(d)

YourResponse:
CorrectAnswer:

Pigmentepithelium

Exp:

ERG

Artifact

Awave

Activityofrodsandcones

Bwave

Bipolarcell

Cwave

Retinalpigmentepithelium(RPE)

(Q.55) Swingingflashlighttestcanbehelpfultoelicit?
(a)
(b)

ArgyllRobertsonpupil
Adiestonicpupil

(c)
MarcusGunnpupil
(d)
Subtleinequalityinpupilsize
YourResponse:
c
CorrectAnswer:
Exp:

Aneyewithnolightperceptionhasnopupillaryresponsetodirectlightstimulation.

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Iftheretinaoropticnerveisonlypartiallyinjured,thedirectpupillaryresponsewillbeweakerthanthe
consensualpupillaryresponseevokedbyshiningalightintotheothereye.
Thisrelativeafferentpupillarydefect(RAPD)MarcusGunnpupilcanbeelicitedwiththeswinging
flashlighttest.
Itisanextremelyusefulsigninretrobulbaropticneuritisandotheropticnervediseases,whereitmaybe
thesoleobjectiveevidencefordisease.

(Q.56) AllthefollowingaretrueaboutRetinitispunctataalbescensexcept?
(a)

Autosomaldominant

(b)
(c)

Retinalpigmentationinepithelium
Particularlyinvolvesposteriorpoleofretina

(d)
Whitedotsonfundusexamination
YourResponse:
c
CorrectAnswer:
Exp:

(Ref:PersonsDiseasesoftheeye20/ePage310)
Retinitispunctataalbescensisaprogressivedegenerativedisorderoftheretinacharacterizedbythe
presenceofnumerouswhitedotsattheleveloftheretinalpigmentepithelium.
Ithasanautosomaldominantmodeofinheritanceandatleastsomecasesareduetomutationin
theRDSgene.Thedotsarefoundthroughoutthefundus,buttendtosparetheposteriorpole.
Despiteaffectedthesamepartsoftheretinaasretinitispigmentosathepigmentarychangesareabsent.
Theretinalpigmentepitheliumhashyperchromaticnuclei,irregularlydistributedmelanin(especiallyatthe
posteriorpole),andcytoplasmicvauoles.
Retinitispunctataalbescensisoneofseveralretinaldiseaseswithwhiteretinaldots(fleckedretina
syndrome).
Otherconditionswithwhitedotsincludefundusalbipunctatus(Stargardtdisease)and
Doynefamilialmaculopathy.

(Q.57) Fleischerringisadistinctfeatureof:
(a)
(b)

Keratoconus
Pterygium

(c)
Congenitalocularmelanosis
(d)
CongenitalepithelialMelanosis
YourResponse:
a
CorrectAnswer:
Exp:

(Ref.Parson,DiseasesofEye,19thed.568)
TYPEOFPIGMENT DISORDER
Iron

LOCATION

Keratoconus(Fleischerring)

Cornealepithelium

Oldopacity(HudsonStahliline)Q

Cornealepithelium

Pterygium(Stockersline)

Cornealepithelium

Filteringbleb(Ferrysline)

Cornealepithelium

Copper

Wilsonsdisease,Chalcosis(KFring)

Descemetsmembrane

Melanin

Pigmentdispersionsyndrome(Krukenbergsspindle)

Endothelium

(Q.58) ForaneonatewithThresholdRetinopathyofprematurity,mostappropriateRxwouldbe:
(a)

Photocoagulation

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(b)

LessO2flow

Surgery

(c)

(d)

YourResponse:
CorrectAnswer:

Exp:

Retinopathyofprematurity

Antioxidants

ROPasper
severity

Meaning

Plusdisease Signofvascularactivitywhichaccompanyany
ROP
stage,indicatinggreaterlikelihoodof
progressiontostageIII(i.e.ridgewith
extraretinalfibrovascularproliferation).

Rx
Retinalablationwithlaser
photocoagulationforthoseprogresing
toprethreshold/thresholddisease

Prethreshold ROPwithincreasedlikelihoodofprogressionto
ROP
retinaldetachmentifleftuntreated.

(Q.59) ICGangiographyisprimarilyindicatedin?
(a)

MinimalclassicalCNV

(b)
(c)

OccultCNV
AngioidstreakswithCNV

(d)
Polypoidalchoroidalvasculopathy
YourResponse:
b
CorrectAnswer:
Exp:

Inalandmarkarticle,YannuzziandassociatesdemonstratedthatICGvideoangiographywasextremely
usefulinidentifyingwelldemarcatedlocalizedareasofneovascularizationinwhathadbeenclassifiedas
occultCNVbystandardfluoresceinangiography.

(Q.60) Entropionis:
(a)
(b)

Inversionofeyelid

Inversionofeyelashes
Eversionofeyelid

(c)

(d)

YourResponse:
CorrectAnswer:

Eversionofeyelashes
a

Exp:

Entropionisaconditioninwhichthelowereyelidturnsinward,rubbingagainsttheeye.Entropionoccurs
mostcommonlyasaresultofaging.Infectionandscarringinsidetheeyelidareothercausesofentropion.
Whentheeyelidturnsinward,theeyelashesandskinrubagainsttheeye,makingitred,irritatedand
sensitivetolightandwind.
Ifentropionisnottreated,aneyeulcermayform.Withsurgery,theeyelidcanbeturnedoutwardtoits
normalposition,protectingtheeyeandimprovingthesesymptoms.

(Q.61) Afterradiationinducedinjurycataractisseeninwhichpartoflens?
(a)

Anteriorcortical

(b)
(c)

Posteriorcortical

(d)

Nucleus

Subcapsular

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YourResponse:
CorrectAnswer:

Exp:

CATARACT

APPEARANCE

1.

Aftercataract(Posteriorcapsularopacity) Elschnigpearl&RingsofSoemerrings

2.

Brown/Cataractabrunescens

Nuclear/hardcataract

3.

Blackcataract/Cataractanigrans

Nuclear/hardcataract

4.

Bluedotcataract(Punctate)

Mostcommoncongenitalcataract

5.

ComplicatedCataract

Breadcrumbappearance&Polychromaticluster

6.

ConcussionCataract

RosetteshapedCataract

7.

Coronarycataract

DevelopmentalCataractatpuberty

8.

Chalcosis

Sunflowercataract

9.

DiabeticCataract(Juvenile)

Snowflake/stormappearance

10.

HypermaturesenileCataract

MorgagnianCataract

11.

Lamellar/Zonular

Riders

12.

Radiationinducedcataract

Posteriorcapsularcataract

(Q.62) Whatsizeofdonorcorneaistakeninkeratoplasty?
(a)

2mm

(b)
(c)
(d)
YourResponse:
CorrectAnswer:

4mm

Exp:

Penetratingkeratoplasty

6mm
8mm

Keratoplastyisreferredtoascornealtransplantationorgrafting.
LamellarKeratoplastyisapartialthicknesscornealgrafting.
PenetratingKeratoplastyisafullthicknesscornealgrafting.
Lamellarrefractivekeratoplastyinvolvestheplacementofalenticuleonorwithinthecorneatoalterits
refractivepower,usuallybychangingitsanteriorcurvature.Lamellarkeratoplastyhastheadvantageof
beingprimarilyoutsidetheeye,makingitaprocedurethatpreservesendothelium.Theriskofrejection
becomeslessofanissue.Therisksofwoundleaksorflatanteriorchambersassociatedwithanintraocular
proceduremaybeeliminated:
2types:
Onlay
Inlay
TheSurgicalProcedure
Decideaboutgraftsize
Usuallygraftsizeisnobiggerthan8.5mmindiametertoavoidpostopincreaseinintraocularpressure,
anteriorsynechiae,andvascularization.
Anidealsizeis7.5mm.Smallersizeswouldgiverisetoastigmatismduetosubsequenttissuetension.
Excisionofdonortissue
Excisionofrecipienttissue

(Q.63) Suddenpainfullossofvisionisseenin:
(a)

Papillitis

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(b)

Centralretinalveinobstruction

(c)
Opticneuritis
(d)
All
YourResponse:
c
CorrectAnswer:
Exp:

Papillitisispainless.Onlyretrobulbarneuritisispainful.
CRVOcausesdecreasedvisionduetomacularedema(painless),CRVOcausesgradual,painfullossofvision
duetoneovascularglaucoma
REDPAINFULEYE

SUDDENVISUALLOSS

CHRONICVISUALLOSS

Cornealabrasions

Amaurosisfugax(TIAofretina)

Cataract

Keratitis

Factitious

Retinitispigmentosa

Herpesophthalmicus

GradeIVHypertensiveretinopathywith
macularstar

POAG

Anterioruveitisor
iridocyclitis

CRVO/BRVO

Epiretinalmembrane

Acuteangleclosure
glaucoma

Anteriorischemicopticneuropathy

DryARMD

Endophthalmitis

Posteriorischemicopticneuropathy

Melanoma&otherocular
tumors

Opticneuritis

Centralserous
chorioretinopathy

Posterioruveitis

Diabeticretinopathy.

Toxicopticneuropathy

Refractiveerror

Vitreoushemorrhage
RD
Classicmigraine
Occipitalinfarct
WetARMD

(Q.64) An18yrsoldboycomestotheeyecasualtywithhistoryofinjurywithatennisball.Onexaminationthereisnoperforationbut
thereishyphema.Themostlikelysourceofthebloodis:

(a)
Irisvessels
(b)
Circulariridismajor
(c)
Shortposteriorciliaryvessels
(d)
Circulariridismajor
YourResponse:
b
CorrectAnswer:
Exp:

(Ref.EssentialofOphthalmologybyBasak2nded.8,303)
Giliarybodyissuppliedbybranchesofmajorcircleofirisformedbytwolongposteriorciliaryarteries&
sevenanteriorciliaryarterieswhichformtheminorcircleifiristhatliesintheirisstroma.
Shortposteriorciliaryarteriesoriginatefromophthalmicarteryas23branches,whicharesubdividedinto
1020branchesthatperforatethescleraaroundopticnerve&directlycommunicatewiththechorio
capillaries.
Hyphaema(collectionofbloodinanteriorchamber)resultsfrominjurytosmallbranchesofcirculusiridis
majorduetotearbetweenlongitudinal&circularfibersoftheciliarymuscles(mostlikelysourceafter

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blunteyetrauma)&mayalsoresultfrominjurytocapillariesofcirculusiridisminorwhenthereis
sphincterictear.

(Q.65) Treatmentofchoiceforphlyctenularconjunctivitisis
(a)
(b)
(c)

(d)

YourResponse:
CorrectAnswer:
Exp:

Topicalsteroids
Sodiumcromoglycate
Zincoxide
AKT
a
(Ref.Parson,Diseasesofeye,18thed.,140)
Aphlyctenule(alsocalledphlycten)isacharacteristicnodularaffectionoccurringasanallergicresponseof
theconjunctivalandcornealepitheliumtosomeendogenousallergenstowhichtheyhavebecome
sensitized.
Aphlyctenule,orphlycten,isasmall,yellowishorpinkishwhitenodulesurroundedbyhyperemic
conjunctiva.Phlyctenmaybesingleormultipleandcanoccuranywhereontheconjunctiva,and
occasionallyonthecorneosclerallimbuswhereitcanbemistakenforacornealforeignbody.
Aetiology:
>Tuberculoprotein
>Toxinsfromstaphylococcusorstreptococcus
>Toxinsfromintestinalparasites
ClinicalTypes:
>Phyctenularconjunctivitis
>PhyctenularKeratoconjunctivitis
>PhyctenularKeratitis
Symptoms:
>Rednesswithformationofbleb
>Irritationandlacrimation
>Painandphotophobia
Treatment:
>Corticosteroideyedrop
>Incaseofsecondaryinfection,firsttreatbacterialconjunctivitisbylocalantibioticdropsandthentreat
withlocalcorticosteroiddrops.
>Whencorneainvolvedatropin(1%)eyeointment
>Improvementofthenutritionalstatus
>Treatmentofcausalfactorseg.
Treatmentoftuberculosis
Treatmentoftonsillitisoradenitis
Antihelminticsforintestinalparasites.
Phlyctenularkeratoconjunctivitis
Isadelayedallergicreactiontomicrobialproteinsortoxins(e.g.staphylococcalinflammation,TB
proteins).
Steroideyedrops.

(Q.66) Recoveryincataractsurgeryisfastestwithwhichofthefollowing?
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(a)
(b)
(c)

(d)

YourResponse:
CorrectAnswer:
Exp:

ICCE
ECCE
Phacoemulsification
ECCEwithIOL
c
(Ref.Parson,DiseasesofEye,18thed.,305;19thed.,180,326)
Principlesofphacoemulsification(asophisticatedformofecce)
Emulsificationoflensnucleusandcorticalmatterbyultrasonicvibrationsusinghollow1mmtitanium
needlevibratingat40,000times/secandthenremovedbysimultaneousirrigationandaspiration.
Assmallas35.5posteriorlimbalgroove/scleraltunnelismadeandwhenincisionis3mm,itiscalled
Suturelesssurgery.
Advantages
Suturelesssurgery
Fastestrecoveryaftersurgery
Earlystabilizationofrefractionwithminimalornoastigmatism
WholeposteriorcapsuleandpartofanteriorareleftintactforinthebagPCIOL.
Disadvantages
Expensiveequipments
Difficulttechnique
Highlytrainedandexperiencedsurgeonneeded
Difficulttouseingrade3+or4+nuclearsclerosis
Complicationswiththebeginnerslikeirisdamage,mixingoflensmaterialwithvitreouscanoccur.

(Q.67) Diplopiaisdiagnosticfeatureof
(a)

(b)

(c)

(d)

YourResponse:
CorrectAnswer:

Concomitantsquint

Exp:

Paralyticsquint
Latentsquint
All
b

(Ref.Parson,DiseasesofEye,18thed.,342;19thed.,180,326;Basak,Ophthalmology,2nded.,298)
Criterion

Concomitantstrabismus

Paralyticstrabismus

Onset

Atanearlyage,initiallyonly
periodically.

Atanyage,suddenonset

Cause

Hereditary,uncorrected
refractive

Diseaseoforinjurytoocularmuscles,nerves,
ornuclei.

error,perinatalinjury
Diplopia

None;imagesuppressed
(exceptin

Diplopiaispresent.

latestrabismuswithnormal
sensory
development)
Compensatory

None

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Present
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headposture
Depthperception

Notpresent

Presentonlywhenpatientassumes
compensatoryheadposture.

Visualacuity

Usuallyunilaterallyreduced
visualacuity

Nochangeinvisualacuity.

Angleofdeviation

Constantineverydirectionof Variable,increasinginthedirectionofactionof
gaze
theparalyzedmuscle.

(Q.68) ScleralExpansionBandsareusedintemanagementof:
(a)
(b)

Myopia

(c)
(d)
YourResponse:
CorrectAnswer:

Presbyopia

Astigmatism
keratoconus
c

Exp:

Schacharintroducedscleralexpansionbandsforsurgicalreversalofpresbyopia.
Originally,theimplantwasdesignedasacontinuousringthatwasplacedintothesclera.
However,presbyopicpatientshadasmuchas10Dofaccommodation,andcomplicationslikeanterior
segmentischemia,bandrotation,andextrusionoccurredaftersurgery.
Themodifiedandimproveddesignofthisprototypeconsistsoffourpolymethylmethacrylate(PMMA)
bandsthatareplacedinfourscleraltunnelsatdepthsof350to400minordertocreatemorespace
betweenthelensandthesclera.
ThisfollowsthetheoryofaccommodationdescribedbySchachar.
Hehypothesizedthatduringaccommodation,thecentralpartofthecrystallinelenssteepensbecauseof
tensionontheequatoriallenszonulesandarelaxedstatusoftheanteriorandposteriorzonules.
Accordingtohistheory,increasingtheworkingdistanceoftheciliarymuscle,achievedbyimplantationof
expansionbands,mightincreasetheamplitudeofaccommodation.
ThistheorycontradictsHelmholtz'stheoryandisnotsupportedbyrecentexperimentalstudies.

(Q.69) Topicalsteroidsareusedintreatmentof
(a)
(b)

Fungalkeratitis
Disciformkeratitis
Viralkeratitis

(c)

(d)

YourResponse:
CorrectAnswer:

Exp:

(Ref.Parson,DiseaseofEye,19thed.,221;Basaksopthalmology,2nded.,123)

Pyogenickeratitis

Disciformkeratitis
Disciformkeratitisisadeepkeratitis(stromal)withdisclikeedema,mainlycausedbyherpesvirus
(sometimesduetovacciniaandherpeszostervirus).
Corticosteroidsaretreatmentofchoice.Topicalcorticosteroiddrops(45timesdaily)underantiviral
cover(acyclovirointment)aregiven.Cycloplegicsmaybeused.

(Q.70) InSturgeWebersyndrome,theocularmanifestationis:
(a)

Retinalhemorrhage

(b)

Pulsatingexophthalmos

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(c)

Lischnodules

(d)
Hemangiomaofchoroidandglaucoma
YourResponse:
d
CorrectAnswer:
Exp:

EncephalotrigeminalangiomatosisorSturgeWebersyndromechildwithsensorimotorseizures
contralateraltoafacial"portwinestain."
Weberprovidedthefirstradiographicdemonstrationofanimportantcomponentofthedisorder,
intracerebralmeningealangiomatouscalcification(characteristictramlinecalcificationseeninsimpleX
ray)ipsilateraltoatrigeminalnevus.
Hemangiomaofchoroidandglaucomaisalsopresent.

(Q.71) Whichofthefollowingmuscleinlidisattachedtouppermarginofsuperiortarsus:
(a)

(b)

(c)

(d)

YourResponse:
CorrectAnswer:
Exp:

Superiorrectus
Muller'smuscle
Levatorpalpebrae
Superioroblique
b
SuperiortarsalmuscleorMuller'smuscleisattacheddirectlytotheuppermarginofsuperiortarsusandis
coveredbyconjunctivaonitsinferiorsurface.
Thetarsiare2thin,elongatedplatesofdensefibroustissueabout2.5cmlong;1isplacedineacheyelid.
Thetarsusoftheuppereyelidislarger,semiovalinshapeandabout10mminheightatthecenter.
Itgraduallynarrowstowardsitsextremities.

(Q.72) Presbyopiaoccursasaresultofthefollowingexcept:
(a)

Lossofelasticityofthecapsule

(b)
Sclerosisoflensfibres
(c)
Reducedanteriormovementofthelens
(d)
Reducedcontractionoftheciliarymuscle
YourResponse:
c
CorrectAnswer:
Exp:

Presbyopiaismultifactorialandisbelievedtoresultfrompoorciliarymusclecontractionwithageand
agerelatedsclerosisandlossofelasticityofthelensfibresandthelenscapsule.

(Q.73) Inachildthenormalresolutionvisualacuitylevelssuchasthatofadultsi.e.6/6isattainedbywhichage?
(a)
(b)
(c)

4months

(d)
YourResponse:
CorrectAnswer:

6years

Exp:

Thenewborn'seyeisshort,23Dhypermetropicandfoveaisimmature

1year
3years

Verysoonafterbirththebabycan'fix'orlookatalighthelpafewincheswaymomentarily.
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1monththefixationoflightbecomesmoresteadyandthebabydevelopsapreferenceforlookingata
faceorfacelikestimulusoveranyotherobjectnearby
3monthbinocularvisionandeyecoordinationareestablishedandtheeyewillfollowatorchhelpedin
frontofthefaceorpersonmovingacrosstheroom.
4monththeinfantdisplayarecognitionpatternsimilartoadultifafaceispresentedupsidedown
6monthofageabilitytoreachout,graspandplaywithsmallobjectsandeffortstoadjustpositiontoseaa
toydevelop
From9monthonwardsformaltestsofvisioncanbeattempted,butitisnotuntil6yearsofagethatthe
normalresolutionvisualacuitylevelssuchasthatofadultsi.e.6/6,20120areattained.
Maturationofinfantvisualfunctionhasbeenstudiedbytwotechniquesthepatternvisualevoked
potential(VEPs)andpreferentiallookingbehavior.Inchildrenyoungerthan2yearstheVEPtestproves
moresuccessful.Inchildrenover2yearswhocanmanagebothtests
Thecriticalperiodfordevelopingthefixationreflexinbothunilateralandbilateralvisualdeprivation
disorderisbetween2and4monthsofage.Anycataractdenseenoughtoimpairvisionmustbedealtwith
beforethisageandtheearliestpossibletimeispreferred.

(Q.74) WhatpercentofretinoblastomasareBilateral?
(a)
(b)
(c)
(d)
YourResponse:
CorrectAnswer:
Exp:

10
20
30
50

c
Retinoblastomaisthemostcommonprimarymalignantintraoculartumorinchildren,occurringin
approximatelyoneof20000births.In30%ofallcases,itisbilateral.

(Q.75) Whichofthefollowingcranialnervepalsyleavestheeyedownandout?
(a)
(b)

Trochlear

(c)
(d)
YourResponse:
CorrectAnswer:

Optic

Exp:

CN3lesioncausesdilatedpupil,downandouteye,droopyeyelid.

Oculomotor
Abducens

OculomotorNerve
Thethirdcranialnerveinnervatesthemedial,inferior,andsuperiorrecti;inferioroblique;levator
palpebraesuperioris;andtheirissphincter.
Totalpalsyoftheoculomotornervecausesptosis,adilatedpupil,andleavestheeyedownandout
becauseoftheunopposedactionofthelateralrectusandsuperioroblique.

(Q.76) Organisminvadingintactcornealmembraneis
(a)

Staphylococcus

(b)
(c)
(d)
Your

Streptococcus
Gonococcus
Pneumococcus

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Response:
Correct
Answer:

Exp:

(Ref.ParsonDiseaseofEye,19thed.,206&Basaks
opthalmology,2nded.,114)
Intactcornealepitheliumcannotbepenetratedbyanyorganism
EXCEPT,
Neisseriagonorrhea
Neisseriameningitides
Corynebacteriumdiphtheriae

(Q.77) Peripheraliridectomyismustinwhichofthefollowing?
(a)
(b)
(c)

Primaryopenangleglaucoma
Absoluteglaucoma
Closedangleglaucoma

(d)
Cataract
YourResponse:
c
CorrectAnswer:
Exp:

(Ref.ParsonDiseaseofEye,19thed.,117,133,306;Basak,Ophthalmology,2nd330)
Filtrationsurgeryforpacg:
Principle:
Theaqueoushumorisdrainedthroughtheanteriorchamberthroughasubconjunctivalscleralopening,
circumventingthetrabecularmeshwork.Formationofathinwalledfiltrationblebisasignofsufficient
drainageofaqueoushumor.
Technique:
Firstaconjunctivalflapisraised,whichmaybeeitherfornixbasedorlimbalbased.Thenapartial
thicknessscleralflapisraised.Accesstotheanteriorchamberisgainedviaagoniotomyperformedwitha
1.5mmtrephineatthesclerocornealjunctionorviaarectangulartrabeculectomyperformedwithascalpel
anddissectingscissors.Aperipheraliridectomyisthenperformedthroughthisopening.Thescleralflapis
thenlooselyclosedandcoveredwithconjunctiva.
Comment:
Apermanentreductioninintraocularpressureisachievedin8085%oftheseoperations.
Peripheraliridectomy(incisionalprocedure)
Wherethecorneaisstillswollenwithedemaortheirisisverythick,anopenproceduremayberequired
tocreateashunt.
Alimbalincisionismadeat12oclockundertopicalanesthesiaorgeneralanesthesia,throughwhicha
basaliridectomyisperformed.
Todayperipheraliridectomyisrarelyperformed,inonlyin12%ofallcases.
Whenthepatientreportsclearprodromalsymptomsandtheangleoftheanteriorchamberappears
constricted,thesafestprophylaxisistoperformaNd:YAGlaseriridotomyorperipheraliridectomy.

(Q.78) Visualacuityininfantsistestedwiththehelpof
(a)
(b)

Landoltsrings

(c)
(d)
YourResponse:

Perimeter

4dottest
Slitlamp
a

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CorrectAnswer:
Exp:

(Ref.Parson,DiseaseofEye,19thed.,93)
Visualacuityismeasureofspatialresolutionofeyeoranestimationofitsabilitytodiscriminatebetween
twopatients.
ALandoltC,alsoknownasaJapaneseVisionTest,LandoltringorLandoltbrokenring,isanoptotype,i.e.
astandardizedsymbolusedfortestingvision.
ItwasdevelopedbytheSwissbornophthalmologistEdmundLandolt.
TheLandoltCconsistsofaringthathasagap,thuslookingsimilartotheletterC.
Thegapcanbeatvariouspositions(usuallyleft,right,bottom,topandthe45positionsinbetween)and
thetaskofthetestedpersonistodecideonwhichsidethegapis.
ThesizeoftheCanditsgaparereduceduntilthesubjectmakesaspecifiedrateoferrors.
Theminimumperceivableangleofthegapistakenasmeasureofthevisualacuity.Itisgenerallypractised
inthelaboratory.

(Q.79) Irisbombeoccursdueto:
(a)

(b)

(c)

(d)

YourResponse:
CorrectAnswer:
Exp:

AdherentGlaucoma
AnteriorSynechiae
PosteriorSynechiae
Ringsynechiae
d
(Ref.Basaks,Ophthalmology,2nded.,pg148)
Ring(annular)synechiae
Posteriorsynechiaeextendingfor360degreesaroundthepupil(seclusiopupillae),preventthepassageof
aqueousfromtheposteriortotheanteriorchamber.Thisgivesrisetoforwardbowingoftheperipheral
iriscausinganirisbombe.
ThismayleadtoelevationofIOPduetosecondaryangleclosurebytheperipheraliris.

(Q.80) Conjunctivalfollicleintrachomawillshow?
(a)

(b)

(c)

(d)

YourResponse
:
Correct
c
Answer:
Exp:

Plasmacell
Epithelioidcells
Lymphocytes
Mastcells

(Ref.BasaksOpthalmology,2nded.,pg100)
TrachomaChronicRareintemperatecountriesbutendemicinwarm

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climates
Lymphoidfolliclesonthepalpebralconjunctivaoftheupper
eyelid.
cicatricialentropion,ptosis,trichiasis,cornealscarring,xerosisof
theconjunctiva.
Causativeagent:Chlamydiatrachomatis(serotypeAC)

(Q.81) A25yearoldmalepresentswithsuddenpainlesslossofvision.Theocularandsystemicexaminationisnormal.Whatisprobable
diagnosis?

(a)
(b)
(c)

Retinaldetachment
Ealesdisease
Glaucoma

(d)

YourResponse:
CorrectAnswer:

Opticneuritis

Exp:

SuddenpainlesslossofvisionoccursinEalesdiseaseduetovitreoushemorrhage.Howevertheocular
examinationwouldrevealvasculitisandvitreoushemorrhage.

Retrobulbarneuritis(opticneuritis)causessuddenprofoundlossofvision.However,ocularexamination
doesnotrevealanyabnormality.
Disease

Features

Eale'sdisease anidiopathicperipheralperiphlebitistypicallyaffectingbotheyesofayoungmale.
presentingfeaturebeingsuddenblurringofvisionduetovitreoushaemorrhage.
unsatisfactorytreatment,laserpanretinalphotocoagulation&parsplanavitrectomy
Opticneuritis isaninflammatory,demyelinatingconditionthatcausesacute,usuallymonocular,visual
loss.
Mostcasesofacutedemyelinatingopticneuritisoccurinwomen(twothirds)andtypically
developinpatientsbetweentheagesof20and40.

(Q.82) Retinitispigmentosaisassociatedwithfollowingexcept:
(a)
Refsum'sdisease
(b)
HallavardianSpatzdisease
(c)
NARP
(d)
Abetalipoproteinemia
YourResponse
:
Correct
b
Answer:
Exp:

Systemicdiseasesassociatedwithretinitispigmentosa:
a.LaurenceMoonBiedlsyndromeb.Usher'ssyndrome
c.Cockayne'ssyndromed.NARPandNeuronalceroid
lipofuscinosis
e.Hallgren'ssyndromef.Waardenburgsyndrome,
g.BardetBiedlsyndromeh.Abetalipoproteinemia
i.KearnsSayresyndromej.Refsumdisease
k.Alportsyndrome
l.Mucopolysaccharidoses(eg,Hurlersyndrome,Scheiesyndrome,
Sanfilipposyndrome)

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(Q.83) Photophthalmiaisseenwith
(a)
(b)

Ultravioletrays

Infraredrays
Gammarays

(c)

(d)

YourResponse:
CorrectAnswer:

Xrays
a

Exp:

Photoophthalmiareferstooccurrenceofmultiplecornealepithelialerosionsduetotheeffectof
ultravioletraysespeciallyfrom311to290nm
Snowblindnessduetoreflectedultravioletraysfromsnowsurface.
Clinicalfeaturessevereburningpain,lacrimation,photophobia,blepharospasm,swellingofpalpebral
conjunctivaandretrotarsalfolds
ProphylaxisCrooke'sglasswhichcutsoffallinfraredandultravioletraysshouldbeusedbythosewho
arepronetoexposureegoWeldingworkers,cinemaoperators
Treatment
Coldcompresses
Padandbandagewithantibioticsfor24hours,healsmostofthecases
Oralanalgesicsifpainisintolerable
Singledoseoftranquilisers
*Photoretinitisdueinfraredrays(eclipseburnofretina)

(Q.84) Angularconjunctivitisiscausedbywhichofthefollowingorganism:
(a)
(b)
(c)
(d)
YourResponse:
CorrectAnswer:
Exp:

Fungus

Bacteroides
Virus
Moraxella
d
AngularconjunctivitisordiplobacillaryconjunctivitisiscausedtypicallyduetoMoraxella.Moraxellaisa
diplobacillusconsistingofapairoflarge,thickrods,placedendtoend.
Thisformofconjunctivitisrespondstooxytetracyclineointment.Zincoxideointmentactsbyinhibitingthe
proteolyticenzymes.

(Q.85) Hornerssyndromecanbecausedbyfollowingexcept:
(a)
Medialmedullarysyndrome
(b)
Carotidaneurysm
(c)
PostoperativeRaynaudsdisease
(d)
Multiplesclerosis
YourResponse:
a
CorrectAnswer:
Exp:

(Ref.HandbookofneurosurgbyGreenberg7th/pg.833;H17th/pg.2527)
ThetriadofmiosiswithipsilateralptosisandanhidrosisconstitutesHorner'ssyndrome,although

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anhidrosisisaninconstantfeature.Alsoenophthalmosandhyperemiaofeyecanoccur.
CausesofHornerssyndrome
1storderneuron

centralneurons

Vascularocclusion(usuallyPICA)
Syringobulbia
Intraparenchymal(hypothalamic,
brainstem)neoplasm

2ndorderneuron

Preganglionic

Lateralsympathectomies
Significantchesttrauma
Pancoasttumor
Highthoracicorcervicalneuroblastoma

3rdorderneuron

Postganglionic

Necktrauma

(1%hydroxyamphitaminecausesNErelease (mostcommon
type)
fromnerveendingsatneuroeffector
junctioncausingpupildilattionin2ndorder

Carotiddiseases(e.g.carotiddissection)

butnotin3rdorderneuronlesions)

Shullbaseneoplasms

Cervicalbonyabnormalities
Migraine
Cavernoussinuslesions(e.g.
meningioma)
Note:withinvolvemntonlyoffibrson
ICA,anhidrosisdoesnotoccur.

(Q.86) Paralysisof3rd,4th&6thnerveswithinvolvementofophthalmicdivisionof5thnerve,localizesthelesionto:
(a)
(b)
(c)

CavernousSinus

Apexoforbit
Brainstem

Baseofskull
(d)

YourResponse:
a
CorrectAnswer:

Exp:

Site
Lateralwallof
CavernousSinus

Cranialnerves
involved
III,IV,VI&first
divisionofVoften
withproptosis

EponymicSyndrome
FoixTolsaHunts

Usualcause
Aneurysmsorthrombosisof
CavernousSinus,invasivetumors
fromSinuses&Sella;benign
granulomas

(Q.87) RecentlyusedtopicalNSAIDforophthalmicuse
(a)
(b)

Indomethacin
Nepafenac
Flurbiprofen

(c)

(d)

YourResponse:
CorrectAnswer:

Exp:

NepafenacisthenewlylaunchedTopicalNSAIDforophthalmicuse.

Oxyphenbutazone

NepafenacisaNSAID,usuallysoldasaeyedrop(0.1%solution).
Itisusedtotreatpainandinflammationassociatedwithcataractsurgery.
Itisusedinmanagementofcystoidsmacularedemabecauseofitsgoodpenetrationinto
theposteriorsegment.
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(Q.88) Trueaboutcomplicatedcataractis
(a)
(b)

Hypertensionisalmostalwayscomplicatedbycataract
Occursonlyinfemales

(c)
Morethan50%casesleadfurthertoendophthalmitis
(d)
Occursonposteriorsurfaceoflens
YourResponse:
d
CorrectAnswer:
Exp:

(Ref.Parson,DiseaseofEye,19thed.,297;Baskasophthalmology2nded.181)
Complicatedcataracts
Resultsfromadisturbanceofthelensmetabolismduetoinflammatoryordegenerativeoculardiseases.
Canoccurasacomplicationofanyprotractedintraocularinflammation,especially
Chroniciridocyclitis,
Retinalvasculitis
Retinitispigmentosa.
Thereisapumicelikeposteriorsubcapsularcataractthatprogressesaxiallytowardthenucleus.
Theopacityusuallycommencesinposteriorcortexintheaxialplane(posteriorcorticalcataract).
Thisformofcataractproducesextremelightscatteringandwithslitlampexamination,theopacityshows
acharacteristicrainbowdisplayofcolors,thepolychromaticluster.
Theopacityhasabreadcrumbappearance
Visionismuchimpairedeveninearlystage,duetopositionoftheopacitynearnodalpointofeye.
Operativeandvisualprognosisisusuallypoor.

(Q.89) Intraoculartensionisdecreasedbyallexcept
(a)
(b)

Pilocarpine

(c)
(d)
YourResponse:
CorrectAnswer:

Apraclonidine

Exp:

(Ref.Parson,DiseaseofEye,18thed.,31)

Atropine
Tropicamide

Occularhypotensivedrugs
1.

Carbonicanhydraseinhibitor

Acetazolamide,
Methazolamide,
Ethoxzolamide
Dichlorophenamide,and
Dorzolamide(topical)

2.

Parasympathomimetics
(miotics)

Pilocarpine
Carbachol
Physostigmine
Demecarium

3.

Sympathomimetic

Epineprine
Dipivefrine
Clonidine
Brimonidine

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Apraclonidine
4.

adrenergics

Timolol
Betaxalol
Levobunolol
Carteolol

5.

Hyperosmoticagents

Metoprolol,
Glycerol
Mannitol
Urea
Isosorbide

6.

Prostaglandinanalogues

Latanoprost(PGF2a)

(Q.90) ThegoldstandardinvestigationforCarotidCavernousFistulas:
(a)
(b)
(c)

Digitalsubtractionangiography
DynamicGadoliniumenhancedMRA
DynamicContrastenhancedmultisliceCT

(d)
ColorDopplerstudywitha7MHZlineartransducer
YourResponse:
a
CorrectAnswer:
Exp:

CarotidCavernousFistulas
Withanteriordrainagethroughtheorbittheseproduceproptosis,diplopia,glaucoma,andcorkscrew,
arterializedconjunctivalvessels.
Directfistulasusuallyresultfromtrauma.Theyareeasilydiagnosedbecauseoftheprominentsigns
producedbyhighflow,highpressureshunting.
Indirectfistulas,orduralarteriovenousmalformations,aremorelikelytooccurspontaneously,especially
inolderwomen.
Thesignsaremoresubtleandthediagnosisisfrequentlymissed.
Thecombinationofslightproptosis,diplopia,enlargedmuscles,andaninjectedeyeisoftenmistakenfor
thyroidophthalmopathy.
Abruithearduponauscultationofthehead,orreportedbythepatient,isavaluablediagnosticclue.
Imagingshowsanenlargedsuperiorophthalmicveinintheorbits.
DSAisbestandgoldstdinvestigationforconfirmingthediagnosisinadditiontothefactthatCarotid
cavernousshuntscanbeeliminatedbyintravascularembolization.

(Q.91) Appreciationofcolorisfunctionof?
(a)
(b)

(c)

(d)

YourResponse:
CorrectAnswer:
Exp:

Rods
Cones
Both,RodsandCones
Choroid
b
(Ref.Parsons,DiseaseofEye,19thed.,131;Khurana,Ophthalmology,3rded.,250)
Sensationofanycolourisdeterminedbytherelativefrequencyofimpulsesforconesystem.
Theappreciationofcolorsisfunctionofconesandoccursinphotopicvision.
Normalcolorvisionistrichromatic,thebasisofYoungHelmoltztrichromatictheoryofcolourvision.
Othertheoriesofcolorvisionare:

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HeringorHurvichandJamesLaw(trichromaticsignalfromconesfedintosubsequentneuralstageand
exhibitspectralapponentandspectralnonopponentproperty),and
EdwinLandwavelengththeory.
Conesarephotoreceptorstightlypackedinfoveacentraliswheretherearenorodsandotherlayersof
retinaareverythinhere.

(Q.92) Advantagesofbinocularindirectophthalmoscopyareallexcept
(a)
(b)
(c)

Peripheralretinacanbevisualized
Widerretinalfieldvisualized
Opacitiesinthemediavisualized

(d)
Morebrightimagesseen
YourResponse:
c
CorrectAnswer:
Exp:

(Ref.Parsons,Diseasesofeye,19thed.,131;18thed.,89)
Ophthalmoscopy
Features

Directophthalmoscopy

Indirectophthalmoscopy

Vitreousopacity

Seen

Opacitiespenetrated

Condensinglens

Notrequired

Required

Examinationdistance Ascloseaspossibleto
patient

anarmsdistance

Accessiblefundus
view

Slightbeyondequator

Widerperipheryofretina,seenuptoora
serrata

Image

Virtual,erect

Inverted,real

Areaoffieldinfocus 2D

8D

Magnification

15times

45times

InHazymedia

Notuseful

Usefulanddetermining

Illumination

NotsoBright

Bright

Absent

Present

10 Steropsis

(Q.93) Atropineiscontraindicatedin
(a)
(b)
(c)

Narrowangleglaucoma
Openangleglaucoma
Congenitalglaucoma

(d)
Steroidinducedglaucoma
YourResponse:
a
CorrectAnswer:
Exp:

(Parson,DiseasesofEye,18thed.,221)
USESOFATROPINE
Atropineisindicatedinchildrenbelowageof7yearsduringretinoscopy.
Itisusedas1%ointmentfor3consecutivedaysbeforeperformingretinoscopy.
Itseffectlastsfor10to20days.
1%atropineeyeointment/dropisusedindecreasingpainfromciliaryspasmandtopreventformationof
posteriorsynechiaefromsecondaryiridocyclitisinpatientsofcornealulcer.
Inacutephasegofiridocyclitis:
Givescomfortandresttotheeyebyrelievingciliaryspasm.

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Preventformationofsynechiaeandmaybreakthesame.
Reducesexudationbydecreasinghyperaemiaandvascularpermeability.
Increasesbloodsupplyofanterioruveabydecreasingpressureofciliaryarteries.
Inaccommodativespasm.
Aspenalizationtreatmentinamblyopia.
Inaccommodativeconvergentsquint.
Contraindicationtoatropine
Anglecloserglaucoma.
Veryshallowanteriorchamber.
Openanteriorchamber.
IrisfixationIOL.

(Q.94) Highestrefractoryofindexisat:
(a)
(b)

Antsurfaceofcornea
Postsurfaceofcornea

(c)
Centeroflens
(d)
Posteriorcapsuleoflens
YourResponse:
c
CorrectAnswer:
Exp:

(Ref:Duanesophthalmology2006edition,vol1,chapter33)
Table:TheGullstrandSchematicEye
Element

Surface

Radius(mm)

Thickness(mm) Refractiveindex Position(mm)

Air
Cornea

1.000
Anterior

7.7

Posterior

6.5

Aqueous
Anteriorlens
cortex

Anterior

10.0

Posterior

7.911

Lenscore
Posteriorlens
cortex

Anterior

5.76

Posterior

6.0

Vitreous
Retina

0.50

0.0
0.50

3.10

1.336

0.546

1.386

3.60

2.419

1.406

4.146

0.635

1.386

6.565
7.20

16.80
12.0

1.376

1.336
24.0

(Q.95) Mostcommoncauseofleukocoriainnewbornis
(a)

Congenitalcataract

(b)
Toxocarainfection
(c)
Retinoblastoma
(d)
CMVinfection
YourResponse
:
CorrectAnswer a
:
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Exp:

(Ref.Khuranaophthalmology4thed.242;ClinicalOphthalmologyby
Kanski,3rded.,225)
AMAUROTICCATSEYE/WHITEPUPILLARYREFLEX(LEUKOCORIA)
a.Congenitalcataractb.Retinoblastoma
c.PHPV(persistenthyperplasticprimaryvitreous)d.ROP
(retinopathyofprematurity)
e.ExtensiveRetinaldetachmentf.MetastaticEndophthalmitis
g.Organizedvitreoushemorrhageh.Toxocaragranuloma
i.Coatsdiseasej.Norriesdisease(pseudotumorof
retina)
k.Massiveretinalgliosisl.Medulloepithelioma
m.PseudogliomaofBlochSclzbergersyndromen.Funduscoloboma
o.Largeatrophicchorioretinalscar

(Q.96) Thefollowingopticalinstrumentisusedfor?

(a)
(b)
(c)

Fielddefect

(d)
YourResponse:
CorrectAnswer:

Nearvision

Exp:

Squint
Colorvision

b
Hessscreentestisusedtomeasurethedegreeofdeviation,andparticularlytomeasureanyprogressive
increaseordecrease,theHessscreentestisuseful.
Itconsistsofatangentscreenmarkedinredlinesonablackclothwithredspotsattheintersectionofthe
15degreeand30degreelineswiththemselvesandwiththehorizontalandverticallines;overitthree
greenthreadsaresuspendedinsuchawaythattheycanbemovedoverthescreeninanydirectionbya
pointer.
Thepatient,wearingredandgreenglasses,isaskedtoplacethejunctionofthethreethreadsoverthered
spotsinturn.
Throughtheredglasshecanonlyseetheredmarkersandthroughthegreen,thegreenthreads,sothat
heindicatedthepointatwhichoneeyeislookingwhentheotherfixesaspot.
Thepositiononwhichtheindicatorappearstocoincidewiththespotgivesapermanentrecordofthe
primaryandsecondarydeviation.

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(Q.97) Steroidinducedcataractis
(a)
(b)
(c)

(d)

YourResponse:
CorrectAnswer:

Posteriorsubcapsular
Anteriorsubcapsular
Nuclearcataract
Cupuliformcataract

Exp:

a
Steroidinducedcataractsteroidsbothsystemicandtopicalarecataractogenic.Thelensopacitiesare
initiallyposteriorsubcapsular;latertheanteriorsubcapsularregionbecomesaffected
Posteriorsubcapsularopacitiesareassociatedwithuseoftopicalaswellassystemicsteroidschildrenare
moresusceptiblethanadults
DruginducedcataractcausedbySteroids,Chlorpromazine,Busulphan,Amiodarone,Gold,
Allopurinol

(Q.98) Whichofthefollowingtumormostcommonlypresentswithbilateralproptosis?
(a)

Leukemia

(b)
Adenocarcinoma
(c)
Fibroushistiocytoma
(d)
Cavernoushemangioma.
YourResponse
:
Correct
a
Answer:
Exp:

98.Ans.a.Leukemia
Causesofbilateralproptosis:
a.Thyroideyediseaseb.Secondariesfromneuroblastoma
c.Leukemicinfiltration.d.Symmetricallymphoma
orlymphosarcoma,
e.Ewingssarcomaandf.craniofacialdysostosise.g.
oxycephaly(towerskull).
g.Osteitisdeformans,ricketsandacromegaly.h.Mikuliczs
syndrome,
i.andlatestagesofcavernoussinusthrombosis.

(Q.99) Comparedwithspectacles,thecontactlenses:
(a)
(b)
(c)

Increasethefieldofvision
Magnifyimagesinhypermetropia
Minifyimagesinmyopia

(d)
Donotreduceaniseikoniaandopticalaberration
YourResponse:
a
CorrectAnswer:
Exp:

Spectaclemagnifiesandminifiesimagesinhypermetropiaandmyopiarespectively.
Ascontactlensestendtoreturntheimagestonearnormalsize,theimagesareminifidinhypermetropia
andmagnifiedinmyopia.
Aniseikoniaie.differencesinimagesizeisreducedwithcontactlenses.

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Contactlensallowthepatienttolookthroughtheopticalcentreinalldirectionofgaze,opticalaberration
isreducedcomparedwithspectacles.

(Q.100) NotafeatureofVenalkeratoconjunctivitisis
(a)
(b)
(c)

Morecommoninsummers
Cobblestoneappearance
Fascicularcornealulcer

(d)
Keratoconus
YourResponse:
c
CorrectAnswer:
Exp:

FascicularulcerisseeninPhlyctenularkeratoconjunctivitis..VKCisIgEmediatedallergytopollens.
Alsoknownasspringcatarrh&ismoreinsummers,Severeitchingandrednessleadstochronicrubbing
whichcanleadtosecondarykeratoconus.
UpperpalpebralpapillaearefoundwhichmaybegiantleadingtoCobblestoneappearance.Leadsto
shieldulcer.
Treatedwithantihistaminics,masrcellstabilizersandtopicallowstrengthsteroids.

(Q.101) Whichofthefollowingistreatmentforchronicdacryocystitis?
(a)
(b)

Dacryocystorhinostomy
Dacryocystectomy

(c)
Massaging
(d)
Syringing
YourResponse
:
CorrectAnswer a
:
Exp:

(Ref.andParsons,DiseaseofEye,19thed.,501,Basak,Ophthalmology,
2nded.,282,336)
Dacryocystorhinostomy(DCR)isthetreatmentofchoiceforchronic
dacryocystitis.

(Q.102) Refractionatanteriorsurfacecorneaismaximumbecause
(a)
(b)

Anteriorsurfaceofcorneahassmallercurvature
Thereisgreaterdifferencebetweenrefractiveindicesofair&cornea.

(c) Itisavasculartransparenttissue.
(d) Alloftheabove.
YourResponse:
b
CorrectAnswer:
Exp:

(Ref.Basak,Ophthalmology,2nded.,4)
Refractivemedia
Refractivemedium

RefractiveIndex

Cornea

1.38

Aqueoushumor

1.33

Lens

1.4

Vitreoushumor

1.34

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Air

Maximumrefractionoccursatanteriorsurfaceofcorneabecause:
1.Anteriorsurfaceofcorneahasgreatercurvature,&
2.Thereisgreaterdifferencebetweenrefractiveindicesofair&cornea.
Refractivesurface

Refractivepower

Anteriorsurfaceofcornea

+48D

Posteriorsurfaceofcornea

4D

Lensofeye(Vivo)

+15D

Lensofeye(takenout)

+150D

(Q.103) "Jackinthebox"phenomenonisbecauseof:
(a)
Lossofaccommodation
(b)
Reducedvisualacuity
(c)
Prismaticeffect
(d)
Sphericalaberration
Your
Response:
Correct
c
Answer:
Exp:

Difficultiesofaphakiaanditscorrectionbyspectaclesareas
under:
Imagemagnificationof30%
Lackofphysicalcoordination
Sphericalaberrationproducinga"pincushioneffect"Q
"Jackinthebox"Qringscotomaduetoprismaticeffectsat
theedgeoflens
PrismaticerrorsQduetodisplacedopticalcentersofthe
lenses
Reducedvisualfieldsandpooreccentricacuity,
Inaccuratecorrectionduetoerroneousvertexdistances
PhysicalinconvenienceandcosmeticblemishduetoYheavy
spectaclelenses

(Q.104) Aftercataractisbesttreatedwith:
(a)
(b)

ARGONLASER
NdYAGLASER

EXIMERLASER
(c)

HolmiumLASER
(d)

YourResponse:
CorrectAnswer: b

Exp:

(Ref.Basak,Ophthalmology,2nded.,182)
Aftercataract
Posteriorcapsularopacification(PCO)followingECCE&discissionof
congenital/traumaticcataract.
Morecommoninchildren

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Elschnigspearl(Balloonlenscell)Q
Soemmeringsring(Ringbehindirisformedbylensfibers)Q
Rx:
Discissionorneedling
Capsulotomy/membranectomyNdYAGLASERcapsulotomy(safe,noninvasive&quick
OPDprocedure).Q

(Q.105) Pseudohypopyonisseenin
(a)

Cornealulcer

Uveitis
(b)

Glaucoma
(c)

Retinoblastoma
(d)

YourResponse:
d
CorrectAnswer:

Exp:

(Ref.Nelson,Pediatrics,7thed.,2115)
Signs(presenting)ofretinoblastomaare:
Initialsigniswhitepupillaryreflex(Leukocoria)
Strabismusissecondmostfrequentinitialsignofretinoblastoma.
Pseudohypopyon(tumorcellslayeredinferiorlyinfrontofiris),causedbytumorseedingin
anteriorchamberoftheeye,
Hyphema,
Vitreoushaemorrage
Signsoforbitalcellulitis.

(Q.106) Tubularvisioniscausedby:
(a)
(b)
(c)

Retinitispigmentosa
Narrowangleglaucoma
Nuclearcataract

(d)
Papilledema
YourResponse:
a
CorrectAnswer:
Exp:

(Retinitispigmentosa)(Ref.Basak,Ophthalmology,2nded.,203)
Astheprimaryopenangleglaucomaadvancestheglaucomatousfielddefectinduetogeneralized
constrictionofperipheralfieldalongwithdoublearcuatescotomaleadstotubularfieldofvision(tubular
vision),inwhichonlythecentralvisionremains.
Causesoftubularvisioninclude:
a.CRAOwithsparingofcillioretinalartery.b.Highmyopia
c.POAGd.Retinitispigmentosa

(Q.107) Ophthalmianeonatorumismostcommonlycausedby
(a)
(b)

Chemicals
Gonococcalinfection

(c)
(d)

Chlamydiaoculogenitalis
Purulentconjunctivitisbybacteria

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YourResponse:
CorrectAnswer:

Exp:

(Ref.Basak,Ophthalmology,2nded.,96)
Ophthalmianeonatorumisconjunctivitisoccurringduringfirstmonthoflife,asaresultof
carelessnessatthetimeofbirth.
Anydischargefromeye(evenwatery)during1stweekoflifeshouldbesuspectedbecausetearsare
notsecretedearlyinlife.
MostcommoncauseofneonatalblindnesstreatmentSulphacetamide10%dropsQIDorTetracycline.
Prophylaxis:Credesmethodbyusing1%silvernitratejustafterbirth(obsoleteasitcauseschemical
conjunctivitis)
Etiology

Timeofmanifestation

Comment

Chemicals

Hours

10%sulfacetamide

Gonococcal

13days

Mostseriousnow,rare

Otherbacterial

45days

Chlamydial

510days

Mostcommoncause

(Q.108) Styeoccursduetoinflammationof:

Muller'sgland

(c)

(d)

YourResponse:
CorrectAnswer:

Meibomiangland

Exp:

STYEorHORDEOLUMINTERNUMisasuppurativeinflammationofoneoftheZeis'gland.

(a)
(b)

Lacrimalgland
Zeis'gland
d

Intheearlystagesofdiseasetheglandbecomeswollen,hardandpainful.
Usuallythewholeedgeofthelidisedematous.
Subsequentlyabscessisformedwhichpointsnearthebaseofoneofthecilia.Painisconsiderable
untilpusisevacuated.

(Q.109) Ringscotomaisseenin?
(a)
(b)
(c)

Chronicsimpleglaucoma
Papillitis
Opticatrophy

(d)
Choroidaldegeneration
YourResponse:
a
CorrectAnswer:
Exp:

(Ref.Basaks,Ophthalmology,2nded.,p203)
Chronicsimpleglaucoma
Inchronicopenangleglaucoma,arelativelylargerarea,ofdefectintheformofarchingscotoma,which
eventuallyfillstheentirearcuatearea,fromblindspottothemedianraphe,isBjerrumsorarcuate
scotoma.
Withfurtherprogression,adoublearcuate(ringorannular)scotomatawilldevelop.
Othercausesofringscotoma:
i.Highmyopiaii.Aphakicspectaclecorrection
iii.Retinitispigmentosaiv.Panretinalphotocoagulation

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(Q.110) Whichofthefollowingisnotcorrectregardingmaculalutea?
(a)
Containsyellowpigment
(b)
Containslargenumberofcones
(c)
Containsrods
(d)
Liesatposteriorpole
YourResponse:
c
CorrectAnswer:
Exp:

(Ref.Graysanatomy,11thed.,SectionX,1c)
Inthemaculaluteathenervefibersarewantingasacontinuouslayer,theganglioniclayerconsistsof
severalstrataofcells,therearenorods,butonlycones,whicharelongerandnarrowerthaninother
parts,andintheouternuclearlayerthereareonlyconegranules,theprocessesofwhichareverylong
andarrangedincurvedlines.
Inthefoveacentralistheonlypartspresentare(1)thecones;(2)theouternuclearlayer,theconefibers
ofwhicharealmosthorizontalindirection;(3)anexceedinglythininnerplexiformlayer.Thepigmented
layeristhickeranditspigmentmorepronouncedthanelsewhere.
Attheoraserrata,thenervouslayersoftheretinaendabruptly,andtheretinaiscontinuedonwardasa
singlelayerofcolumnarcellscoveredbythepigmentedlayer.

(Q.111) Whatisthediagnosis?

(a)

Hordeoluminternum

(b)

Hordeolumexternum

(c)
Chalazion
(d)
Blepharospasm
YourResponse:
b
CorrectAnswer:
Exp:

ThisisasuppurativeinflammationofaZeisgland.Intheearlystagestheglandbecomesswollen,hard
andpainful,andusuallythewholeedgeofthelidisoedematous.
Anabscessformswhichgenerallypointsnearthebaseofoneofthecilia.
Thepainisconsiderableuntilthepusisremoved.Styesoftenoccursincrops,ormayalternatewithboils
ontheneck,carbuncles,oracne,usuallyindicatingadeficientresistancetostaphylococci.
Itiscommonestinyoungadults,butmayoccuratanyage,especiallyindebilitatedpersons.

(Q.112) Inlateralrectusmuscleparalysis,thediplopiaproducedis:
(a)

Uncrossed

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(b)

Crossed

(c)

Both

(d)
YourResponse:
CorrectAnswer:

None
a

Exp:

Paralysisoflateralrectusmuscle:Thereislimitationofoutwardmovementofeyeballandfaceisturned
towardstheparalyzedside.Homonymous(uncrossed)diplopiaoccursonlookingtotheparalyzedside.
Diplopia(doublevision)isthechiefcomplaintofthepatientsofparalysisofextrinsicmusclesofeyeball.
Iftheobjectasseenbytherighteyeistotherighttotheobjectseenbythelefteye,thentheconditionis
knownashomonymous(uncrossed)diplopia.
Onthecontraryiftheobjectasseenbythelefteyeliesapparentlytotherightoftheobjectasseenby
therighteye,theconditionisknownasheteronymous(crossed)diplopia.

(Q.113) Shaffersignisseenin:
(a)

Acuteglaucoma

(b)
(c)

Retinaldetachment
Uveitis

(d)

YourResponse:
CorrectAnswer:

Retinoblastoma

Exp:

(Ref:Parson,29thEdition,Page312)

Pigmentintheanteriorvitreous(tobaccodustingorShaffersign)isusuallypresent.
Afterafewweeks,aretinaldetachmentmaypresentwithmorefixedfolds,retinalthinning,intraretinal
cysts,subretinalfibrosis,anddemarcationlines.
Theselinesarepresentusuallyatthejunctionoftheattachedanddetachedretina.

(Q.114) Completeocclusionofthecentralretinalarteryischaracterizedby?
(a)

Rothsspots

(b)
(c)

Cherryredfovea

(d)

YourResponse:
CorrectAnswer:
Exp:

Hollenhorstplaques
Cottonwoollesions
b
Completeocclusionofthecentralretinalarteryproducesarrestofbloodflowandamilkyretinawitha
cherryredfovea.
Emboliarecomposedofeithercholesterol(Hollenhorstplaque),calcium,orplateletfibrindebris.
Whitecenteredretinalhemorrhages(Rothsspots)areconsideredpathognomonicforsubacutebacterial
endocarditis,buttheyalsoappearinleukemia,diabetes,andmanyotherconditions.

(Q.115) Thepowerofacontactlensisdeterminedbywhichofthefollowingallexcept?
(a)
(b)

Thickness

(c)

Oxygenpermeability

Posteriorcurvature

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(d)

Refractiveindex

YourResponse
:
CorrectAnswer c
:
Exp:

Thepowerofacontactlensisdeterminedbyits:
a.Anteriorcurvatureb.Posteriorcurvaturec.Thicknessd.
Refractiveindex.

(Q.116) NotseeninLaurenceMoonBiedlsyndrome:
(a)
(b)

Obesity

Retinitispigmentosa

(c)
Sexualunderdevelopment
(d)
Retinaldetachment
YourResponse:
d
CorrectAnswer:
Exp:

LAURENCEMOONBIEDLSYNDROMEisacombinationofobesity,sexualunderdevelopment,mental
retardation,retinaldegeneration,polydactyly,anddeformityoftheskull.
Itisinheritedasanautosomalrecessivetrait.LaurenceMoonBiedlsyndromeisthemostcommon
syndromeassociatedwithretinitispigmentosa.

(Q.117) WhichofthefollowingeyediseasemostcommonlyhasAutosomaldominantinheritancepattern?
(a)

Gyrateatrophy

(b)
(c)

BestDisease

(d)

YourResponse:
CorrectAnswer:
Exp:

Retinoschisis
StargardtDisease
b
BestDisease(VitelliformDystrophy)ischaracterizedbyalesioninthemacula,whichleadstoimpaired
centralvisioninoneorbotheyes.Itisanautosomaldominantdisease.
StargardtDisease/FundusFlavimaculatus
Thisformofmaculardegenerationusuallyappearsbeforetheageof20.Itischaracterizedbyareduction
ofcentralvisionwithapreservationofperipheralvision.Inmostaffectedfamilies,Stargardtandfundus
flavimaculatusareautosomalrecessivediseases,althoughautosomaldominantfamilieshavebeen
identified.

(Q.118) Ridersareseenin?
(a)

Bluedot

(b)
(c)

Zonularcataract

(d)

YourResponse:
CorrectAnswer:
Exp:

Coralliformcataract
Traumaticcataract
b
InZONULARCATARACTtheopacityisusuallysharplydemarcatedandtheareaofthelenswithinand
aroundtheopaquezoneisclear,althoughlinearopacitieslikespokesofawheel,calledriders,mayrun

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outwardstowardstheequator.
Occasionallytwosuchringsofopacityareseen.

(Q.119) Causesofcherryredspotonfundusincludefollowingexcept:
(a)

TaySachsdisease,

(b)
(c)

NiemannPickdisease,
Sandhoffsdisease

(d)
Fabrysdisease
Your
Response:
Correct
d
Answer:
Exp:

D/Dofcherryredspotonfundus
a.CRAO,b.Bluntinjury(Berlinsedemaofmacula),
c.TaySachsdisease,d.NiemannPickdisease,
e.Sandhoffsdisease

(Q.120) Whenusingtheplanemirrortechniqueduringretinoscopy,whichoneofthefollowingstatementsstandswrong?
(a)

A'with'movementisneutralizedwithapluslens

(b)

An'against'movementisneutralizedwithaminuslens

(c)
A'with'movementalwaysindicateshypermetropia
(d)
An'against'movementalwaysindicatesmyopia
YourResponse:
a
CorrectAnswer:
Exp:

Withtheplanemirrortechnique,pluslensisusedtoneutralizewithmovementandminuslensfor
againstmovement.
Whileanagainstmovementalwaysindicatesmyopia,awithmovementmaybeseeninmyopicpatientif
themyopiaislessthanthedioptricvalueoftheobserver'sworkingdistance(forexampleatadistanceof
2/3m,awithmovementisseenifthemyopiaislessthan1.50D.
Theneutralpointoccurswhenthepatient'sfarpointcoincideswiththeobserver'snodalpoint..

(Q.121) Painlesslossofvisionisseenin:
(a)

Vitreoushemorrhage

(b)
(c)

Opticatrophy
Developmentalcataract

(d)
AcuteAngleclosureglaucoma.
YourResponse:
a
CorrectAnswer:
Exp:

(Ref.Basak,Ophthalmology,2nded.,215)
Vitreoushemorrhageisassociatedwithsuddenpainlesslossofvision&onattemptedophthalmoscopy
thefundusglowischaracteristicallyabsentasthefundusishiddenbyadarkredhazeofblood.
Itcanoccurduetoretinal&vitreousdetachment,indiabetes,sicklecelldisease,hypertension&otheris
chemicoccurdisease.

(Q.122) Inelectroretinogram(ERG),awave,largenegativewaveisgeneratedby:
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(a)

Retinalpigmentepithelium

(b)
(c)

Rods&conesreceptoractivity.
Responseofamacrinecells

(d)
All
YourResponse:
CorrectAnswer:

Exp:

(Ref.Basak,Ophthalmology,2nded.,21)
ERG
Electroretinographymeansgrossrecordofelectricalpointial,changesintheretinaoften
stimulationwithlength.
Largenegativeawavewhichreflectsphotoreceptor(rods&cones)activity.
Thenalargepositivebwavefollowsduetoresponseofbipolarcells.
Lastly,asmallpositivecwaveisgeneratedbyretinalpigmentepitheliallayer.
Durationofentireresponse<250ms.
USES:
Usefulindistinguishingretinalandopticnervedysfunctionfrommaculardiseases.
Assessesretinalfunctioninpresenceofopacityinmediainsiderosisbulbi.
Usefulin
Corticalandhystericalblindness,
Retinitispigmentosa,
Chorioretinitis,
Rodandconedysfunction,and
Toxicretinopathy.

(Q.123) Retinoscopyisusedto?
(a)

Todeterminedegreeofametropia.

(b)
(c)

ToknowconditionofRefraction
Testingvisualacuity

(d) Tomeasureastigmatismofanteriorcornealsurface.
YourResponse:
CorrectAnswer: a
Exp:

(Ref.Basak,Ophthalmology,2nded.,72)
Retinoscopy
Mostpracticalmethodofestimatingconditionofrefractionobjectively,with
accommodationatrest.
Principleistomakeeveryobservingeyeemmetropic,sothatemergingraysshould
formparallelbeam.
StreakretA)Todeterminedegreeofametropia.
inoscopyeasilydeterminesaxisofastigmatism,canbedoneinanyposition,children
andpreoperatively.
Cycloplegiamayberequiredchildren,howevernotadvisableundercycloplegia.
Itshouldpreferablybeconductedinadarkroom.
Sourceoflightshouldbebehindthepatient.
Inhypermetropia,emmetropia&myopia<1Dreflexmoves,reflexsamedirection.
Inmyopiaof1Dnomovement.
Inmyopia>1Dshadowmovesoppositedirection.

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(Q.124) Indacryocystorhinostomy(DCR)lacrimalsacisdirectlyopenedinto:
(a)

Superiornasalmeatus

(b)

Middlenasalmeatus

(c)

(d)

YourResponse:
CorrectAnswer:

Inferiornasalmeatus
Nasolacrimalduct
b

Exp:

(Ref.Basaks,Opthalmology,2nded.,pg,282,336)
DACROCYSTORHINOSTOMY(DCR)issurgicalprocedureofchoiceinchronicdacryocystitis,inwhicha
communicationismadebetweenlacrimalsacandmiddlemeatusofnose.
Contraindications:a.DNSb.Atrophicrhinitisc.Carcinomaoflacrimalsac

(Q.125) Amongtheretinalganglioncells,thefastestsignaltransmissiontothebrainandpromptresponsivenessforrapidchangesin
visualimageisthefunctionof:

(a)

Wcells

(b)
(c)

Ycells

(d)
YourResponse:
CorrectAnswer:

Horizontalcells

Exp:

Xcells

b
(Ref.Aldersphysiologyofeye10thed.718)
Theconesrespondtobrightlightandmediatehighresolutionvisionandcolorvision.
Therodsrespondtodimlightandmediatelowerresolution,blackandwhite,nightvision.
Humanshavethreedifferenttypesofcones(trichromaticvision).
Whenlightfallsonareceptoritsendsaproportionalresponsesynapticallytobipolarcells,whichinturn
signaltheretinalganglioncells.Thereceptorsarealsocrosslinkedbyhorizontalcellsandamacrine
cells,whichmodifythesynapticsignalbeforetheganglioncells.
Intheretinalganglioncellstherearetwotypesofresponse,dependingonthereceptivefieldofthecell.
InONcells,anincrementinlightintensityinthecenterofthereceptivefieldcausesthefiringrateto
increase.InOFFcells,itmakesitdecrease.Beyondthissimpledifference,chromaticsensitivityandthe
typeofspatialsummationalsodifferentiateganglioncells.
CellsshowinglinearspatialsummationaretermedXcells(alsocalledparvocellular,P,ormidget
ganglioncells),andthoseshowingnonlinearsummationareYcells(alsocalledmagnocellular,M,or
parasolretinalganglioncells).
AccordingtoLoewenfelditappearsthat3maintypesofganglioncellsmakeuptheprimateretina
dependingonthepropertiesofthemajorclassesofganglioncellsandtheirprojections:thealpha,beta
andgammacells.IncatsthesecorrespondtotheY,XandWcells,respectively.

(Q.126) A19yrboywitha2yrH/Oreduced&fluctuatingvisionalongwithchangeinpupillaryshapeandiriscolourinhislefteye

presentedtotheglaucomaclinic.O/Erevealeddistinctunilateralstretchholes,irisarchitecturechangesandlocalizedirisatrophy.
IOPwas16inRt&36mmHginLteye.Gonioscopyoftheleftanglerevealedbroadbasedperipheralanteriorsynechiaeat
approximately2O'clockto10O'clockposition.Theopticdiscofthelefteyehadaverticalcupof0.9whichmanifestassuperior
andinferiorarcuatescotoma.Specularmicroscopyshowedunilateralabnormalendotheliumwithirregularcellsofvariableshape
andsize.
Whatcanbeprobablediagnosis?

(a)

Glaucoma

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(b)

Iridocornealendothelialsyndrome

(c)

Uveitis

(d)
None
YourResponse:
CorrectAnswer:
Exp:

b
http://www.aao.org/publications/eyenet/201110/pearls.cfm
Unknownetiology.
Characterizedby
i.Glaucoma,ii.Irisatrophy,
iii.Decreasedendothelium,andiv.Irisnodules.
Aftermetaplasia,thecornealendotheliumproliferates,andDescemetsmembranelikematerialcovers
theanteriorsurfaceandangleoftheanteriorchamber,causingirisanomaliesandsecondaryglaucoma.
Thespectrumincludes3conditions:
i.Progressiveessentialirisatrophyii.Chandlerssyndrome
iii.Irisnaevussybdrome
Iridocornealendothelial(ICE)syndromecomprisesaspectrumofthreeclinicalvariations:Chandler
syndrome,progressiveirisatrophyandCoganReesesyndrome.Althoughinitiallydescribedseparately
andwithdistinctclinicalmanifestations,thesevariantsarelinkedbyafundamentaldefectofthecorneal
endotheliumasshownbyhistopathologicandultrastructuralstudies
ClinicalFeatures
DistinguishingclinicalfeaturesofICEsyndromeareasfollows.
Symptoms.
Acommonpresentingcomplaintisanacquiredabnormalityoftheshapeorpositionofonepupil.
SomepatientswithICEsyndromereportreducedvision,whichistypicallyworseinthemorningbecause
ofcornealedemathatdevelopswhentheeyelidsareclosedduringsleepandimprovesduringthedayas
thecorneadehydrateswithexposuretoair.
Signs.
ClinicalexaminationofapatientwithICEsyndromeusuallyrevealsabnormalitiesofthecornea,anterior
chamberangleandiris.
ThetypicalcornealabnormalityinICEsyndromeisseenbyslitlampexaminationasafine,hammered
silverappearanceoftheposteriorcornea,similartothatofFuchsdystrophybutlesscoarse.
Onspecularmicroscopy,cornealendothelialcellsarereducedinnumberandrevealvariabledegreesof
pleomorphisminsizeandshape,withlossofhexagonalmargins.
Theseabnormalcellsalsoshowdarklightreversal,withcellboundariesappearingbrightandcellsurfaces
dark.
ThesecellsaresometimescalledICEcells,andthetissuetheyform,ICEtissue.
Thetypicalanteriorchamberangleabnormality,whichisalsocommontoallvariationsofICEsyndrome,
isseenbygonioscopyasperipheralanteriorsynechiaethatmayextendanteriortoSchwalbesline.These
iridotrabecularadhesionsarebroadbasedandtypicallyprogressgraduallyaroundthecircumferenceof
theangle,eventuallyleadingtoangleclosureandIOPelevation.

(Q.127) ERGdepicts:
(a) Changesinrestingpotentialofeyeinducedbyaflashoflight
(b) Informationaboutanteriorchamber
(c) Functionalabnormalitiesofpigmentlayerofretina
(d) Conditionsinvolvingganglioncellsandhigherpathway
YourResponse
:
CorrectAnswer
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Exp:

(Ref.OphthalmologybyA.K.Khurana2nded.40;Ganongphysiology21st
ed.162)
Electroretinography
Itistherecordofchangesinrestingpotentialofeyeinducedbyaflashof
light.
NormalERGhas:
Awave:Negativewavearisingfromrodsandcones
Bwave:LargepositivewavegeneratedbyMullercells,butrepresents
activityofbipolarcells.
Cwave:Positivewaverepresentingmetabolicactivityofretinalpigment
epithelium.
FovealERGcanprovideinformationaboutmacula.
ERGisusefulindetectingfunctionalabnormalitiesofouterretina.
ERGisnormalindiseasesinvolvingganglioncellsandhigherpathway,suchas
opticatrophy.

(Q.128) InwhichofthefollowingconditionFrillexcisionisdone:
(a)

Foreignbodyineye

(b)
(c)

Panophthalmitis
Endophthalmitis

(d)
Intraoculartumor
YourResponse:
b
CorrectAnswer:
Exp:

OnlyindicationofeviscerationofeyeballaresomecasesofpanophthalmitisQtopreventtheextension
ofinfectionuptheopticnervesheath.
OneofthemethodsofeviscerationisFrillexcisioninwhichtheinsertionsofextraocularmusclesarecut
andgreaterpartofscleraisexcisedleavingonlyacollarofscleraaroundtheopticnerve.

(Q.129) Trueaboutmacularhole?
(a)

ItismorecommoninMalesthaninfemales

(b)

Usuallybilateral

(c)
Watzke'ssignpositive
(d)
Majorityofmacularholesresolvespontaneously.
YourResponse:
c
CorrectAnswer:
Exp:

Amacularholeisalesioninthefovea.Amacularholelookslikeaholeordepressedcircularorovalarea
thattypicallyisreddishinappearance.
Tothepatientamacularholelookslikeadarkareaorscotomainwhichthepatientcan'tseethrough.
Priortoafullblownmacularhole,a"premacularholelesion"maybepresentandthesehavebeen
referredtobyvariousnamesincludingmacularcyst,involutionalmacularthinningorimpendingmacular
hole.
Dependingontheseverity,sizeandlocationofthemacularhole,thepatientmayhavefromabout20/50
to20/400visualacuityintheaffectedeye.
TheslitlampcanbeusedtodetectthepresenceofmacularholeusingtheWatzke'ssign.Somemacular
holes,about10%,partiallyresolveorimprove,butthemajorityarepermanentasisthelossofvision.

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Usuallyonlyoneeyeisaffectedandwomenareaffectedmuchmorethanmen.Traumatotheeye
accountsforabout15%ofmacularholes,whiletherestaretypicallyassociatedwithaging(50and
older).

(Q.130) Trueaboutthekeratometerisfollowingexcept?
(a) Usesthecorneaasaconvexmirrorinthemeasurementofcornealcurvature
(b) Measuresonlythecentral3mmofthecornea
(c) Canbemisleadinginpatientswhohavehadcornealtransplantation
(d) Ismoreimportantinfittingsoftcontactlensthanrigidgaspermeablecontactlens
YourResponse:
d
CorrectAnswer:
Exp:

ThekeratometerusesthefirstPurkinjeSamson'simage.
Itmeasuresonlythecentral3mmandcanbemisleadinginpatientswhohavehadradialkeratectomy
orcornealtransplant.
Tonegatetheocularmovement,thecentralimageisdoubledduringkeratometry.
Keratometryisimportantforcontactlensfittingbutmoresoforrigidgaspermeable(RGP)contact
lensthansoftcontactlens.

(Q.131) Ectopialentisisafeatureof:
(a)

Marfanssyndrome

(b)

Homocystinuria

(c) WeilMarchesanisyndrome
(d) Alloftheabove
Your
Response
:
Correct d
Answer:
Exp: Causesoflensdislocation

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(Q.132) Tigroidfundusisseenin?
(a)

Severemyopia

(b)
(c)

Choroidalsclerosis
Retinitispigmentosa

(d)

YourResponse:
CorrectAnswer:

Retinoblastoma

Exp:

b
(Ref:Parson,29thEdition,Page134)
Inpeoplehavingalightpigmentation,thechoroidandsometimesitslargervesselsmaybevisible.
Sometimesthepigmentbetweenthechoroidalvesselsisparticularlydense,orthepigmentisdeficientin
theretinalpigmentaryepithelium,whilethechoroidisdeeplypigmented;thechoroidalvesselsarethen
seentobeseparatedbydeeplypigmentedpolygonalareas(tigroidortesselatedfundus).
Thisappearanceisoftenduetoaconditioncalledchoroidalsclerosisandmaybeaccompaniedbyadry
agerelatedmaculardegeneration.

(Q.133) Cobblestoneappearanceofconjunctivaisseenin:
(a)
(b)

Springcatarrh
Angularconjunctivitis

(c)
Eczematousconjunctivitis
(d)
Trachoma
YourResponse
:
CorrectAnswer a
:
Exp:

(Ref:OphthalmologybyAKKhurana2nded.100)
Springcatarrh(vernalkeratoconjunctivitis)
Recurrent,bilateral,interstitial,selflimitingallergic
Signs:
Palpebralform:
Presenceofhard,flattoppedpapillaearrangedincobblestoneor
pavementstonefashion.
Papillaemayhypertrophytoproducecauliflowerlikeexcrescences(Giant
papillae).
Bulbarform:
Duskyredtriangularcongestionofbulbarconjunctivainpalpebralarea.
Gelatinousthickenedaccumulationoftissuearoundlimbus
Discretewhitishraiseddotsalongthelimbus(HornerTrantasspots)
Mixedform:Featuresofpalpebralandbulbarform.
Vernalkeratopathy:
Punctuateepithelialkeratitis
Ulcerativevernalkeratitis(Shieldcornealulcer)
Vernalcornealplaques
Subepithelialscarring
Pseudogerontoxon(classicalCupidsbowoutline)
Rx:
Topicalvasoconstrictors

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Sodiumcromoglycate(2%)
Weakaceticaciddrops(0.20.5%)
Topicalantihistaminics
Topicalsteroids(Medrysone,betamethasone,dexamethasone)
topicalCyclosporine.

(Q.134) Bullseyemaculopathycanbecausedbywhichofthefollowing?
(a)
(b)

Quinine
Chloroquine

Amiodarone
(c)

Digoxin
(d)

YourResponse:
b
CorrectAnswer:

Exp:

(Ref.KDTripathiPharmacology5thed.239)
Chloroquine
Chloroquine,basicallyaantimalarialdrugs,isalsofoundtoinduceremissioninupto50%patients
ofRheumatoidarthritis.
Chloroquine/hydroxychloroquineareemployedinmildernonerosivedisease
Whengivenforrheumatoidarthritis,ithastobegivenforlongperiods.
Thisislesscommonandreversibleincaseofhydroxychloroquine,whichispreferredover
chloroquine.
Otheradverseeffectsare:
i.Rashes,ii.Grayingofhair,iii.Irritablebowelsyndrome,
iv.Myopathyandv.Neuropathy.

(Q.135) Commonestcauseofposteriorstaphylomais:
(a)
(b)

Glaucoma
Retinaldetachment

(c)
Iridocyclitis
(d)
Highmyopia
Your
Response:
Correct
d
Answer:
Exp:

(Ref:OphthalmologybyAKKhurana2nded.151)
POSTERIORSTAPHYLOMA
Itreferstobulgingofweaksclerabehindtheequatorlined
bythechoroid.
Commoncausesare:
Pathologicalmyopia,
Posteriorscleritisand
Perforatinginjuries.
DiagnosedbestonindirectophthalmoscopyandUSG(Bscan)
Itisseenasanexcavatedareawithretinalvesselsdippingin
it.

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(Q.136) Tyndalleffectisusedin?
(a)

Biomicroscopy

(b)
(c)

Fluorescenceangiography
Treatmentofretinoblastoma

(d)
Checkingofintraocularpressure
YourResponse:
a
CorrectAnswer:
Exp:

(Ref:Parson,29thEdition,Page134)
Thebasisofbiomicroscopyofthevitreousbody,aqueousflareistheTyndalleffect.
Thisismaximalwithahighintensityofprojectedlight,agoodcontrastbetweentheobservedstructure
andbackground,alargeangleofseparationbetweenobserverandilluminationaxesandwhenviewedby
adarkadaptedeye.

(Q.137) Squintcausedbyexcessiveeffortofconvergencewithsustainedaccommodationisdueto:
(a)

Myopia

(b)

Hypermetropia
Astigmatism

(c)

(d)

YourResponse:
CorrectAnswer:

Exp:

(Ref.ParsonsDiseaseofEye18thed.341,Basakophthalmology2nded.298)

Anisometropia

Hypermetropia
Thesecondprincipalfocusofhypermetropialiesbehindtheretina.
Accommodationisusedtocorrecttheemmetropiatocertainextent.
Theyrequirereadingglassesearlierthanthenormalpopulation.
Aphakiaisaformofhighhypermetropia.
Followingcataractsurgery,theaccommodativeabilityoftheeyeislost.
Therefore,ifthepatientishypermetropic,thevisionwillbeblurredfordistantandnear.Thisisthe
reasonwhymostpatientsaremadeslightlymyopicsothattheycanachieveareasonablevisionwithout
glassesfordistance.

(Q.138) Rossetesarecharacteristicallyseenin:
(a)

Retinoblastoma

(b)
(c)

Pulmonaryblastoma

(d)

YourResponse:
CorrectAnswer:
Exp:

Hepatoblastoma
Pancreatoblastoma
a

(Ref.Robbinspathology7thed.500,1442;Table.1010;Basaksophthalmology3rd.ed.227)
Nephroblastoma(Wilmstumor),hepatoblastoma,andneuroblastoma,Ewingstumor,.Owingtotheir
primitivehistologicappearance,havebeencollectivelyreferredtoassmallroundbluecelltumors.
Therosettesseenare:
FlexnerWintersteinerrosettes(specific)

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HomerWrightrosettes

(Q.139) ThebestaccountedfunctiontoMIP26inlens?
(a)

Glucosetransport

(b)

Regulationofwatercontent

(c)
Ionicbalance
(d)
Anerobicglycolysis
YourResponse:
b
CorrectAnswer:
Exp:

MIP26
FUNCTION:
Waterchannel.
Mayberesponsibleforregulatingtheosmolarityofthelens.
SUBCELLULARLOCATION:
Membrane;
Multipassmembraneprotein.
TISSUESPECIFICITY:
Majorcomponentoflensfibergapjunctions.
DOMAIN:
Aquaporinscontaintwotandemrepeatseachcontainingthreemembranespanningdomainsandapore
formingloopwiththesignaturemotifAsnProAla(NPA).
DISEASE:
DefectsinMIPareacauseofautosomalrecessivecongenitalcataract.

(Q.140) Riddochphenomenonisseeninlesionof?
(a)
(b)

Retina
EdingerWestphalnucleus

(c)
Occipitallobe
(d)
Optictract
YourResponse:
c
CorrectAnswer:
Exp:

(Ref:Parson,20thedition,Page475)
Occipitallobehemianopiasareextremelycongauous,havingahomogeneousdensitywithsparingofthe
macula.
Riddochphenomenon,inwhichappreciationofadimkinetictargetisretainedwithinthedefectivevisual
fieldwithlossofappreciationofastaticbrighttarget,istypicalofanoccipitallesion.

(Q.141) TrueaboutARP?
(a)
(b)

Lightreflexispresent
Accommodationreflexispresent

(c)

SynonymouswithAdiespupil

(d)
Associatedwithdorsalmidbrainlesions
YourResponse:
b
CorrectAnswer:
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Exp:

ThesyphiliticlesionofthetectumaffectingthepupillarypathwayoftenresultsinArgyllRobertson
pupilwhereinthepupilsaresmallandthelightreactionisimpaired,butthereactiontoconvergenceand
accommodationareretained.

(Q.142) Phlyctenisdueto
(a)
(b)

Endogenousallergen
Exogenousallergen

(c)
Persistentirritation
(d)
Infection
YourResponse:
a
CorrectAnswer:
Exp:

(Ref:AKKhurana2nded:102)
PHLYCTENULARKERATOCONJUCTIVITISisacharacteristicnodularinflammationoccurringasanallergic
responsebyconjunctival&cornealepitheliumtosomeendogenousallergenstowhichtheyhavebecome
sensitized.ItistypeIVcellmediatedreactiontostaphylococcusproteins(mostcommon
cause),tuberculosisproteins,orMoraxellaAsxenfieldbacillusandcertainparasites(worminfestation).

(Q.143) Heteronymoushemianopiaisduetolesionat
(a)

Opticnerve

(b)
(c)

Opticchiasma
Lateralgeniculatebody

(d)
Cerebralcortex
YourResponse:
b
CorrectAnswer:
Exp:

(Ref.Harrison'sPrinciplesofInternalMedicine16thEdition164165)
Heteronymoushemianopia
Heteronymoushemianopiameansbitemporalorbinasalhemianopia.
Attheopticchiasm,fibersfromnasalganglioncellsdecussateintothecontralateraloptictract.
Crossedfibersaredamagedmorebycompressionthanuncrossedfibers.
Asaresult,masslesionsofthesellarregioncauseatemporalhemianopiaineacheye.
Tumorsanteriortotheopticchiasm,suchasmeningiomasofthetuberculumsella,produceajunctional
scotomacharacterizedbyanopticneuropathyinoneeyeandasuperiortemporalfieldcutintheother
eye.
Moresymmetriccompressionoftheopticchiasmbyapituitaryadenoma,meningioma,
craniopharyngioma,glioma,oraneurysmresultsinabitemporalhemianopia.
Homonymoushemianopia
Itisdifficulttolocalizeapostchiasmallesionaccurately,becauseinjuryanywhereintheoptictract,
lateralgeniculatebody,opticradiations,orvisualcortexcanproduceahomonymoushemianopia,i.e.,a
temporalhemifielddefectinthecontralateraleyeandamatchingnasalhemifielddefectintheipsilateral
eye.

(Q.144) Argonlaserisnotusefulin
(a)

C.R.V.occlusion

(b)
(c)

Retinitispigmentosa
Retinaldetachment

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(d)

Diabeticretinopathy

YourResponse:
CorrectAnswer:

Exp:

(Ref.Harrison'sPrinciplesofInternalMedicine16thEdition172)
Retinitispigmentosa
Thisisageneraltermforadisparategroupofrodandconedystrophies
Itischaracterizedbyprogressivenightblindness,visualfieldconstrictionwitharingscotoma,lossof
acuity,andanabnormalelectroretinogram(ERG).
Itoccurssporadicallyorinanautosomalrecessive,dominant,orXlinkedpattern.
Irregularblackdepositsofclumpedpigmentintheperipheralretina,calledbonespiculesbecauseoftheir
vagueresemblancetothespiculesofcancellousbone,givethediseaseitsname.
Thenameisactuallyamisnomerbecauseretinitispigmentosaisnotaninflammatoryprocess.
Mostcasesareduetoamutationinthegeneforrhodopsin,therodphotopigment,orinthegenefor
peripherin,aglycoproteinlocatedinphotoreceptoroutersegments.
VitaminA(15,000IU/day)slightlyretardsthedeteriorationoftheERGinpatientswithretinitis
pigmentosabuthasnobeneficialeffectonvisualacuityorfields.
Someformsofretinitispigmentosaoccurinassociationwithrare,hereditarysystemicdiseases
(olivopontocerebellardegeneration,BassenKornzweigdisease,KearnsSayresyndrome,Refsums
disease).
Chronictreatmentwithchloroquine,hydroxychloroquine,andphenothiazines(especially
thioridazine)canproducevisuallossfromatoxicretinopathythatresemblesretinitispigmentosa.
Thereisnospecifictherapyforretinitispigmentosa.
Geneticcounsellinghelpsinthenonpropagationofthedisease.

(Q.145) Photoretinitisisduetoexposureto
(a)

U.V.rays

(b)
(c)

Infraredrays
Gammarays

(d)
Xrays
YourResponse:
CorrectAnswer: b
Exp:

(Ref:AKKhurana2nded:263)
Photoretinitisisprimarilyaburnofthefoveolarregionresultingfrominfrared
raysofbrightsunlight.
HencealsocalledSOLARRETINOPATHY/ECLIPSEBURNofretina.

(Q.146) KayserFleischerringinvolvestheregionof
(a)
(b)

Bowmansmembrane

(c)

Stroma

Descemetsmembrane

(d)
Epithelium
YourResponse:
b
CorrectAnswer:
Exp:

(Ref:AKKhurana2nded.378;ParsonsDiseaseOfEye19thed.568)

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PIGMENTTYPEDISORDERLOCATION
IronKeratoconusCornealepithelium
(Fleischerring)
OldopacityCornealepithelium
(HudsonStahhline)
PterygiumCornealepithelium
(Stockersline)
FilteringblebCornealepithelium
(Ferrysline)
CopperWilsonsdisease,ChalcosisDescemetsmembrane
(KFring)
MelaninPigmentdispersionsyndromeEndothelium
(Krukenbergsspindle)
Kfring
KayserFleischer(KF)ringincorneaisadiagnosticfeatureofWilsonsdiseaseorhepatolenticular
degeneration.
ItisagoldenbrownringwhichoccursduetodepositionofcopperunderperipheralpartsofDescemets
membraneofthecornea.

(Q.147) Superiororbitalfracturedoesnotinvolve
(a)

IIcranialnerve

(b)

IIIcranialnerve
IVcranialnerve

(c)

(d)

YourResponse:
CorrectAnswer:

Exp:

(Ref.Harrison'sPrinciplesofInternalMedicine16thEd.)

VIcranialnerve

Superiororbitalfissurefracture
Superiororbitalfissuresyndrome,alsoknownasRochonDuvigneaud'ssyndrome,isaneurological
disorderthatresultsifthesuperiororbitalfissureisfractured.
Involvementofthecranialnervesthatpassthroughthesuperiororbitalfissuremayleadtodiplopia,
paralysisofextraocularmotions,exophthalmos,andptosis.
Blindnessorlossofvisionindicatesinvolvementoftheorbitalapex,whichismoreserious,requiring
urgentsurgicalintervention.

(Q.148) PilocarpinecausesallEXCEPT
(a)

Salivation

(b)

Miosis

(c)
Sweating
(d)
Cycloplegia
Your
Response:
Correct
d
Answer:
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Exp:

Pilocarpine
Pilocarpineisalocalparasympathomimeticocular
hypotensivedrug
Itsmioticeffectisusefulinthemanagementofangleclosure
glaucoma.
Itisnotacycloplegicdrug.
However,itssystemiceffectsinclude
i.Increasedsweating,ii.Increasedsalivation,
iii.Bronchospasm&iv.Abdominalcramps.
Contraindicationstopilocarpine:
i.Inflammatoryglaucomaii.Malignant
glaucomaiii.Allergy

(Q.149) Stockerslineispathognomonicof
(a)

Cholestaticjaundice

(b)

Pterygium

(c)
Hemochromatosis
(d)
Decreasedceruloplasminlevel
YourResponse:
b
CorrectAnswer:
Exp:

TYPEOFPIGMENT

DISORDER

LOCATION

Keratoconus(Fleischerring)

Cornealepithelium

Oldopacity(HudsonStahhline)

Cornealepithelium

Pterygium(Stockersline)

Cornealepithelium

Filteringbleb(Ferrysline)

Cornealepithelium

Copper

Wilsonsdisease,Chalcosis(KFring)

Descemetsmembrane

Melanin

Pigmentdispersionsyndrome(Krukenbergs
spindle)

Endothelium

Iron

(Q.150) Besttovisualizecornealendothelium

Fundoscopy

(c)

(d)

YourResponse:
CorrectAnswer:

Slitlampexam

(a)
(b)

Exp:

Specularmicroscopy
Operatingmicroscopy
b
Specularmicroscopy
Itisvitaltocountandstudymorphologyofcornealendothelialcells,especiallyinthecasesofcataract
withsuspectedendothelialdystrophy.
Normalcellcountis20002500cells/mm2.
IOLimplantationiscontraindicatedifthecellcountis<1500/mm2.
Specularreflectionbyslitlampbiomicroscope(specularmicroscopy)allowsvisualizationofcorneal
endotheliumbyviewinglightreflectedbackfromthisinterface,countofendothelialcellsispossibleusing
anElsergrid.

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(Q.151) Formaddoxrodtestdistancefrompatientshouldbe?
(a)

0.5m

(b)

1m

(c)
(d)
YourResponse:
CorrectAnswer:

2m
6m

Exp:

Diagnosisofheterophoria/latentstrabismusdependsontheabolishingfusionsothat,withitscontrol,
theeyesassumetheirpositionofrest.
Severaltestsareavailableforassessingangleofdeviation:
Covertest
Madoxrodtest(Therodisheldinfrontoftheeyes,imageofhighestpointclosetoeyebecomedissimilar
andfusionbecomesdissociated).Testsperformanceat6meterand35cmdistance.
Maddoxwingtest
Prismvergencetest
Synaoptophore

(Q.152) Pinkfunduscanbeseeninallthefollowingconditions
except

(a)

Papilledema

(b)

Pseudopapilledema

(c)
Papillitis
(d)
Retinitispigmentosa
Your
Response
:
Correct d
Answer:
Exp:
(Q.153) Primaryangle=secondaryangleofdeviationisseeninwhichsquint
(a)

Concomitant

(b)

Paralytic
Latent

(c)

(d)

YourResponse:
CorrectAnswer:

Exp:

Squint

None

S.No.

Concomitant(Aparalytic)

Paralytic(Nonconcomitant)

1.

Suddenonset

Insidiousonset

2.

Developmentalorigin

Acquired

3.

Infantsandchildren

Adultsaffected

4.

Diplopia

Nodiplopia

5.

Normalheadposture

Abnormalheadposture

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6.

Nofalseprojection

Falseprojection+

7.

Angleofsquintconstantinalldirectionof
gaze

Variableangleofsquint

8.

Normalocularmovement

Occularmovementsrestricted

9.

Secondaryangleofdeviation=primaryangle Secondaryangle>primary

10.

Amblyopia

Noamblyopia

11.

Goodsurgicalresults

Notsatisfactory/contraindicated

(Q.154) Rosettecataractisseenin
(a)

Concussioninjury

(b)

Penetratinginjury

(c)

(d)

YourResponse:
CorrectAnswer:

Diabetesmellitus

Exp:

(Ref.Parson,DiseasesofEye,18thed.,283;Basak,Ophthalmology,2nded.,182,305)

Chalcosis
a

CATARACT
Aftercataract(postcapopacity)

Elschnigpearl&ringsofSoemerrings

Brown/(cataractabrunescens)

Nuclear/hardcataract

Blackcataract/(cataracatnigrans)

Nuclear/hardcataract

Bluedotcataract(punctate)

Mostcommoncongenitalcataract

Complicatedcataract

Breadcrumbappearance

Concussioncataract

Rosetteshapedcataract

Coronarycataract

Developmentalcataractatpuberty

Chalcosis

Sunflowercataract

Diabeticcataract

Snowflake/stormappearance

Hypermaturesenilecataract

Morgagniancataract

Lamellar/zonular

Riders

(Q.155) Lensusedtotreatmyopiais
(a)

Convex

(b)

Concave

(c)
Cylindrical
(d)
Anyoftheabove
YourResponse:
CorrectAnswer b
:
Exp:

(Ref.Parson,DiseasesofEye,18thed.,65)
Myopia(shortsightedness)
Mostcommonisaxialmyopia
Clinicallysimplemyopiaismostcommon
Ifits>6D,calledhighmyopia
Treatment
OpticalConcavelenses

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Surgical
a).Radialkeratotomyb).Keratophakiac).Keratomileusis
d).LAISK(LaserassistedinsituKeratomileusis)e).Fukalasoperationf).
Scleroplasty
MinusIOL
ExcimerLASER(Photorefractivekeratoplasty/PRK)
IndicationsforLASIK:
a).Stablerefractiveerrorb).Age>21yearsc).Unsatisfactoryresultofnon
surgicaltreatment
ContraindicationforLASIK:
a).Cornealthinningdisordersb).Diabetesmellitus

(Q.156) Alloccurinprocessofaccommodationofeyeallexcept
(a)
(b)

Contractionofsphincterpupillae
Dilatationofpupil

(c)

Changeinlenscurvature

(d)
Contractionofciliarymuscles
YourResponse
:
CorrectAnswer b
:
Exp:

(Ref.Parson,DiseasesofEye,18thed.,49,Basak,2nded.,68)
ACCOMODATIONisabilitytoseenearobjectsclearly,byincreasing
convergingpowerofeye.
Componentsofneartriadinclude:
Constrictionofciliarymusclesandsphincterpupillae
Constrictionofpupil
Changeinlenscurvature(anteriorsurface)

(Q.157) DacryocystorhinostomyiscontraindicatedinallEXCEPT
(a)

Atrophicrhinitis

(b)
(c)

DNS
Carcinomalacrimalgland

(d)
Chronicdacryocystitis
YourResponse:
CorrectAnswer: d
Exp:

(Ref.Parson,DiseasesofEye,18thed.,376,19thed.,501504;Basak,
Ophthomology2nded.,282,336)
Dacrocystorhinostomy(DCR)
Itissurgicalprocedureofchoiceinchronicdacrocystitis.
Acommunicationismadebetweenlacrimalsacandmiddlemeatusofnose.
Contraindications:
i.DNSii.Carcinomaoflacrimalglandiii.Rhinitis(Atrophic)

(Q.158) Abductionandelevationofeyeiscaused
by

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(a)

Superioroblique

(b)
(c)

Inferioroblique
Superiorrectus

(d) Medialrectus
Your
Response
:
Correct b
Answer:
Exp:
(Q.159) Whichfieldofvisionislasttogoinchronicsimpleglaucoma?
(a)

Nasal

(b)
(c)

Peripheral

(d)
YourResponse:
CorrectAnswer:

Temporal

Exp:

Central

d
InPOAG(chronicsimpleglaucoma)glaucomatousdiscchangesarecharacteristicwithcuppingstartingin
inferiortemporalquadrant,followedbybayonetingsign,baringofcircumlinearvessels,splinter
hemorrhages,neuralrimthinning,polarnotching,laminardotsignandopticpallorandatrophy.
Fielddefectsincludeisoptercontraction,baringofblindspot,arcuate(Bjerrum)scotoma,superior
paracentralscotoma,Seidelsscotoma,ringscotoma,Roennesnasalstep,tubularfieldandlastlyonly
temporalislandofvision.
TreatmentofPOAG(primaryopenangleglaucoma):
Medicaltreatmentisalwaysfirstinplace,operativetreatmentislastresort.
Pilocarpine,betablockers,epinephrine,dipivefrin,dorzolamide,andlatanoprostareused.
LatanoprostisaPGanalogue,whichactsbyincreasingtheuveoscleraloutflow.
LASERArgonLaserTrabeculoplasty(ALT)
Newertrabeculotomywithantimetabolitesandvalveimplantation.
Filteringsurgeries.
TreatmentofPACG(primaryangleclosureglaucoma)
Pilocarpine24%,butdefinitiveissurgery,PBI,butnowreplacedinmostcasesbyLASERiridotomy.
ColoredhalosessentialsymptomofPACG.

(Q.160) Besttreatmentforbuphthalmosis
(a)
(b)

Trabeculectomy

(c)

Cryotherapy

Goniotomy

(d)
Conservative
Your
Response:
Correct
b
Answer:
Exp:

Buphthalmos
Treatmentofchoiceforbuphthalmosisgoniotomy.

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Eventualsuccessratewithgoniotomyis85%.
Howeverinresistantcasestrabeculectomyandtrabeculotomyare
helpful.
Trabeculotomyisusefulwhencornealcloudingispresentorwhen
goniotomyfails.

(Q.161) Whichofthefollowingdrugisbeingusedinthetreatmentofdiabeticretinopathy?
(a)

Etanercept

(b)
(c)

Eculizumab
Bevacizumab
Infliximab

(d)

YourResponse:
CorrectAnswer:

Exp:

Bevacizumabisadrugthatblocksangiogenesis,thegrowthofnewbloodvessels.
Itisusedtotreatvariouscancers,includingcolorectal,lung,andkidneycancer,andeyedisease.
BevacizumabisahumanizedmonoclonalantibodythatinhibitsvascularendothelialgrowthfactorA(VEGF
A).
VEGFAisachemicalsignalthatstimulatesangiogenesisinavarietyofdiseases,especially
incancer,retinalproliferationofdiabetesintheeye.

(Q.162) DamagetonervesupplyingSuperiorobliquecausesdiplopiainwhichdirection?
(a)
(b)

Horizontalanddownward

(c)

Horizontalandupward

Verticalanddownward

(d)
Verticalandupward
YourResponse:
a
CorrectAnswer:
Exp:

(Ref.BDCVol.3.4th/pg.115)
Trochlearor4thcranialnerveproducesdiplopiaduetoparalysisofSuperiorobliquemusclewhichoccurs
inhorizontalanddownwardgaze.

(Q.163) Whatisthediagnosis?

(a)
(b)

Blepharophimosis

(c)

Ankyloblepharon

(d)

Ectropion

Symblepharon

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YourResponse:
CorrectAnswer:
Exp:

d
Cicatricialectropioniscommonlytheresultofburns,traumaandchronicinflammationsoftheskinwhich
shortentheanteriorlamellaoftheeyelid,i.e.theskinmusclelayers.Thispullstheeyelidmarginaway
fromtheglobe.

(Q.164) LocalAntifungalagentusedincornealfungalinfection?
(a)

Silversulfadiazine

(b)
(c)

Neomycin
Griseofulvin

(d)
Natamycin
YourResponse
:
CorrectAnswer d
:
Exp:

(Ref.Basaksophathalmology2nded.pg.120)
Treatmentofmycotickeratitis
Scrapinganddebridement
Atropineeyeointment
Antifungaldrugs:
Topical
Natamycin(5%)eyedrops,1hourly.Effectiveagainstmostcommonfungi.
Miconazole(1%)eyeointment,5timesdaily.
Nystatineyeointment,5timesdaily.Onlyeffectiveagainstcandida,andless
potent.
TopicalamphoterecinB(0.25%),1hourly,effectiveagainstAspergillusand
candida.
Systemic
Ifulcerismarginalorperforated,tab.Ketoconazoleorfluconazolefor23
weeksmaybetried.
Therapeuticfullthicknesskeratoplastyismuchbettersolution.

(Q.165) Awelldefinedfocallesionintheconeofextraocularmusclesoftheeyewithproptosisinachild.Thediagnosiswillbe?
(a)

Cavernoushemangioma

(b)
(c)

Hemangioendothelioma
Capillaryangioma

(d)
Retinoblastoma
YourResponse:
a
CorrectAnswer:
Exp:

(Ref.Grainger&Allison'sDiagnosticRadiology:ATextbookofMedicalImaging,4thEd.pg.2534)
Thecapillaryangiomaisatumourofearlychildhood.Itformsasoft,bluishmass,whichmayinvolveany
partoftheorbit,includingtheeyelid.
USshowsitasawelldefinedanteriorsoftlesionwithsmallirregularechoes.CDFIshowspathognomonic
featureswithhighflowwithinimmaturevesselsinahypervascularizedmass.Sincethesetumoursregress
eitherspontaneouslyoraftersteroids,CTisonlyindicatedfortumourswithretrobulbarextension.
Cavernoushaemangioma,thecommonestprimaryretrobulbartumour,isaslowgrowing,welldefined,

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roundedorovalmassconsistingoflargevascularspacessurroundedbyafirmcapsule.Usuallyitlies
withinthemusclecone,displacingtheopticnerve,andiswelldepictedbyUS,CT,andMRI.Phleboliths
arenotuncommon.

(Q.166) Rothsspotsareoccurdueto?
(a)

Retinalhemorrhages

(b)
(c)

Retinalinfarct

(d)

YourResponse:
CorrectAnswer:

Retinaledema

Retinaldetachment

Exp:

Whitecenteredretinalhemorrhages(Roth'sspots)areconsideredpathognomonicforsubacutebacterial
endocarditis,buttheyalsoappearinleukemia,diabetes,andmanyotherconditions.

(Q.167) TELECANTHUSmeans?
(a)

Increasedintercanthaldistancewithnormalinterpupillarydistance.

(b)

Increaseddistancebetweenmedialcanthusandeyelids

(c) Widelyseparatedmedialwalloforbits
(d) Widelyseparatednoseandmedialcanthi
YourResponse:
a
CorrectAnswer:
Exp:

Telecanthus,referstoincreaseddistancebetweenthemedialcanthioftheeyes,whiletheinterpupillary
distanceisnormal.
Thisisincontrasttohypertelorism,wheretheinterpupillarydistanceisincreased.
Thedistancebetweentheinnercornerofthelefteyeandtheinnercorneroftherighteye,iscalled
intercanthaldistance.
Inmostpeople,theintercanthaldistanceisequaltothedistancebetweentheinnercornerandtheouter
cornerofeacheye,thatis,thewidthoftheeye.
Thesituation,whereintercanthaldistanceisintenselybiggerthanthewidthoftheeye,iscalled
telecanthus.
Thiscanbeanethnicindexoranindicationforhypertelorismorhypotelorism,ifitiscombinedwith
abnormalrelationtotheinterpupillarydistance.

(Q.168) Seafanretinaisseenin?
(a)
(b)

CRAO

(c)

Sicklecelldisease

SLE

(d)

YourResponse:
CorrectAnswer:

Gauchersdisease

Exp:

(Ref.Khuranaophthalmology5th/pg.271)

Prolifertiveretinopathycanoccurinsicklecelldisease:

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Stage1:Peripheralarteriolarocclusion
Stage2:PeripheralAVanastomoseswhichappeartobedilatedpreexistentcapillarychannels.
Stage3:Sproutingofnewvesselsfromanastomoses.Initiallythenewvesselslieflatontheretina,havea
seafanconfigurationandfedbyasinglearterioleanddrainedbysinglevein.
Stage4:Vitreoushemorrhage.
Stage5:ExtensivefibrovascularproliferationandtractionalRD.

(Q.169) Keraticprecipitatesandcellsinanteriorchamberaresuggestiveof?
(a)
(b)

Glaucoma

(c)

Conjunctivitis

Scleritis
Iridocyclitis

(d)

YourResponse:
CorrectAnswer:

Exp:

(Ref.Khuranaophthalmology5th/pg.271)
Signsofanterioruveitis:
Circumcornealinjection
Keraticprecipitates(KP)arecellulardepositsonthecornealendothelium.KPmostforminmidand
inferiorzonesofcornea.
i.Endothelialdustingii.MediumsizeKPs
iii.LargeKPs(MuttonfatKps)granulomatousuveitis.iv.OldKPs
Cells
Aqueosflare
Irisnodules(KoeppeandBusaccanodules)

(Q.170) Antiglaucomadrugthatislongactingandusedoncedaily?
(a)

Brimonidine

(b)
(c)

Dorzolamide
Latanoprost

Timolol
(d)

YourResponse:
d
CorrectAnswer:
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Exp:

(Ref.KDT6th/pg.144)
Drug/class

Aqueous
secretion

Trabecularoutflow

Uveoscleraloutflow

1. blockers(Timolol)

2. Miotics(Pilocarpine)

3. Adrenaline/Dipivefrine

4. Brimonidine/apraclonidine

5. Prostaglandins(Latanoprost)

6. Carbonicanhydraseinhibitors

(Q.171) Whichofthefollowingisnottrueaboutthedirectophthalmoscope?
(a)
(b)

Givesanangularmagnificationof15X
Givesarealerectimage

(c)

Makesthediscofamyopeappearslargerthanthatofahypermetrope

(d) Isbetterthanindirectophthalmoscopeindetectingdiabeticmaculopathy
YourResponse:
d
CorrectAnswer:
Exp:

Thedirectophthalmoscopegivesanangularmagnificationof15X.Theimageformedisvirtualanderect.
Thesizeoftheopticdiscwhenviewedthroughadirectophthalmoscopeislargerinmyopethan
emmetrope,whichinturnislargerthaninhypermetrope.
Diabeticmaculopathyisbetterdetectedwithindirectophthalmoscope.

(Q.172) FosterKennedysyndromeisdueto
(a)

Frontallobetumour

(b)
(c)

Parietallobetumor

(d)

YourResponse:
CorrectAnswer:
Exp:

Temporallobetumour
Occipitallobetumour
a
(Ref:AKKhurana2nded:285)
FOSTERKENNEDYSYNDROMEisassociatedwitholfactoryorsphenoidalmeningioma&frontallobe
tumours.
Inthisconditionthereoccurspressureopticatrophyonthesideoflesions&papilloedemaontheother
side(duetoraisedintracranialpressure).

(Q.173) Retinoscopywithaplanemirrorfromadistanceofonemetergivesnoimage.Diagnosis
is

(a)

Aphakia

(b)

Emmetropia

(c)

(d)

YourResponse
:
Correct

Myopia1D
Hypermetropia

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Answer:
Exp:
(Q.174) Inophthalmoplegicmigraine,whichnerveisinvolvedfirst?
(a)
(b)

IVcranialnerve

(c)

VIcranialnerve

IIIcranialnerve

IIcarinalnerve
(d)

YourResponse:
CorrectAnswer: b

Exp:

(Ref.Harrison'sPrinciplesofInternalMedicine16thEd.88)
Ophthalmoplegicmigraine
Ophthalmoplegicmigraineisanuncommondisorderusuallyhavingitsonsetinthefirst
decadeoflife
Themigrainousattackisfollowedbypartialparalysisofthethirdand/orthesixthcranial
nerve.
Theparalysismaylastfordaysorweeks.
Ptosis,limitationofocularmovementssemidilatedpupilsandsluggishpupillaryreactionsare
theclassicalfeatures
Recoveryisgradualandtendstobecomelesscompletewithrepeatedattacks.

(Q.175) Notacommonsymptomofconjunctivitis:
(a)
(b)

Pain

(c)

Discharge

(d)
YourResponse:
CorrectAnswer:

Irritation

Exp:

Redness

a
Conjunctivitisisthemostcommoncauseofared,painfuleye.ButPainisminimal,Painisminimal,and
thevisualacuityisonlyslightlyreduced.
Themostcommonviralcauseisadenovirusinfection.
Itcausesawaterydischarge,mildforeignbodysensation,andphotophobia.
Bacterialinfectionproducesamoremucopurulentexudate.

(Q.176) AllthefollowingdrugsareusedinacuteanterioruveitisEXCEPT
(a)

Pilocarpine

(b)

Atropine

Timolol
(c)

Propranolol
(d)

YourResponse:
CorrectAnswer: a

Exp:

Treatmentofacuteanterioruveitis
cycloplegicsdilatationofthepupilandrelaxationoftheciliarymusclewithsuch
as:

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i.atropineQ1%ii.cyclopentolateoriii.homatropine2%.
NSAIDS(Aspirin)
Localandsystemiccorticosteroids
Immunosuppressivedrugs
Hotfomentation
Pilocarpineisdirectactingparasympathomimeticdrug.
Itcausescontractionoflongitudinalmuscleofciliarybodyandopensspacein
trabecularmeshwork
itiscontraindicatedinanterioruveitis

(Q.177) Vossiusringis
(a)
(b)

Pigmentationonthecornea
Depigmentationoftheiris

(c)

Circularpigmentrimontheanteriorcapsuleoflens

(d) Degenerationoftheretina
YourResponse:
CorrectAnswer: c
Exp:

(Ref:AKKhurana2nded:373)
VOSSIUSRINGisacircularringofbrownpigmentseenontheanteriorcapsuleof
thelens.
Itoccursduetoimprintofcontractedpupillarymarginagainstthecrystallinelens,
duringblunttrauma

(Q.178) Pepper&Saltappearanceoffundusisduetotheinfectionof
(a)

Rubella

(b)

Herpes

(c)
(d)
YourResponse:
CorrectAnswer:

AIDS

Exp:

Measles

a
(Ref:ParsonsDiseasesifEye20thed.302,AKKhuranaophthalmology3rded:288)

APPEARNACEONFUNDOSCOPY

DIAGNOSIS

Saltandpepperfundus

Congenitalrubella
CongenitalsyphilisMayousBattendisease
Lebersamaurosis
Thioridazinetoxicity

(Q.179) CornealNeovascularizationcanbepreventedby
(a)
(b)

Photocoagulation

(c)

Systemiccorticosteroids

Radiationofpituitary

(d)
Localcorticosteroids
YourResponse:
CorrectAnswer: a
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Exp:

Thevascularisationofthecorneamaybepreventedbyphotocoagulatingthevessles..
Applicationofcorticosteroids&Thioteopaorbirradiationiseffective.Intractablecasesare
dealtwithperitomy.

(Q.180) TheonlyindicationforArgusIIis:
(a)
(b)

Retinitispigmentosa

Retinoblastoma

(c)
Retinaldetachment
(d)
choroidalneovascularization
YourResponse:
a
CorrectAnswer:
Exp:

Theartificialretina,calledtheArgusIIRetinalProsthesisSystem,isthefirstimplantabledevicetotreat
theconditionandisapprovedforpeopleoverage25withadvancedRPwhocanseesomelight.
Thedeviceconsistsofapanelofelectrodesthataresurgicallyimplantedintheeye,andapairofglasses
withanattachedcamera.
Thecamerasendsimagestotheelectrodes,essentiallybypassingthedamagedretinaandtappinginto
theopticnervethatsignalsthebrain.

(Q.181) ChronicIridocyclitisisafeatureofwhichofthefollowingdisease:
(a)

PolyarticularRFve

(b)

PolyarticularRF+ve

(c)

(d)

YourResponse:
CorrectAnswer:
Exp:

PauciarticulartypeI
PauciarticulartypeII
c
JRA

Systemic

Polyarticular

Polyarticular

Pauciarticular

Pauciarticular

RFve

RF+ve

TypeI

TypeII

Percentage

20%

25%

10%

30%

15%

Sacroiliitis

No

No

Rare

No

Common

Iridocyclitis

No

Rare

No

50%chronic 20%acute

Rheumatoid
factor

Negative

Negative

100%

Negative

Negative

ANA

Negative

25%

75%

60%

Negative

Boys/girls

60%boys

90%girls

80%girls

80%girls

90%boys

(Q.182) Forpanophthalmitistrueis
(a)

Mostcommoncauseisendogenous

(b)
(c)

Painlessocularmovementsareseen
Ophthalmologistmayelecttodoaparsplanavitrectomy

(d)
Noneoftheabove
YourResponse:
c
CorrectAnswer:
Exp:

Panophthalmitis >inflammationofalllayersoftheeye.

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Etiology

Endogenous(215%)>fromthehematogenousspreadoforganismsfroma
distantsourceofinfection.Seenwith(endocarditis,immunosuppressiveagents
orcandidalinfectionsinIVdrugusers).Exogenous(60%)>directinoculation
(mostfromocularsurgery,canbefromforeignbodies,blunt/penetrating
trauma).MostduetoG+suchasStaphaureusorepi.

Riskfactors

Recenteyesurgery,fevers,oculartrauma,hammeringsteelwithsteel,working
withbalingwire,orworkinginanindustrialsetting.

S/s

Pain(worsewithoccularmovement),erythema,lidswelling,occulard/c,and
blurredordecreasedvisualacuity.Rangesfromwhitenodulesontheiris/retina
orchoroidtoinflammationofalltheoculartissueswithpurulentexudate.Fungal
endophthalmitismaypresentasanindolentcourse(dayswks).Candidalmay
presentwithhighfever,thendayslaterwithocularsxs.Otherfindingsinclude
injectedconjunctiva,hypopyon,chemosis,decredreflex,proptosis(latefinding),
papillitis,cottonwoolspots,cornealedema,Rothspots(whitecentered
hemorrhagesintheretina).

Rx

Peretiology.Tetshot,admit,startempiricAbx(topical+Vanc+aminoglycoside
ora3rdGenCeph,+ClindauntilBacillusspcanberuledoutifsoilcontamination,
+FluconazolePO),considerintravitrealAbxifvisualacuityislimitedtolight
perception.Cycloplegicagent(atropine),andtopicalsteroidsareoftenused.
Ophthalmologistmayelecttodoaparsplanavitrectomy.AspirationofpusforCx
andpossiblyintraocularsteroids.

(Q.183) Finchamstestisdonetodifferentiatebetween
(a)

Acutecongestiveglaucomaandcataract

(b)

Chronicsimpleglaucomaandcataract

(c)
Acutecongestiveglaucomaandchronicsimpleglaucoma
(d)
Chronicsimpleglaucomaandiridocyclitis
YourResponse:
a
CorrectAnswer:
Exp:

(Ref:AKKhurana2nded:233)
Finchamstestcandifferentiatedbetweenthehalosofglaucoma&immaturecataract.
ColouredhalosinPACGoccurduetoaccumulationoffluidinthecornealepitheliumandalterationinthe
refractiveconditionofthecorneallamellae.
Thesemustbedifferentiatedfromthosefoundinacutepurulentconjunctivitis&earlycataractous
changes.Inconjunctivitis,haloscanbeeliminatedbyirrigatingthedischarge.
Thehalosofglaucoma&immaturecataractmaybedifferentiatedbyFinchamstestinwhichstenopaeic
slitispassedacrosspupil.
GlaucomatousHaloremainsintactwhilehaloduetocataractisdiscontinuousorsegmented

(Q.184) Chloroquineinlargedosescauses
(a)

Cornealdeposits

(b)

Glaucoma

(c)
Cataract
(d)
Irreversibleretinopathy
YourResponse:
d
CorrectAnswer:
Exp:

(Ref:ParsonsDiseasesifEye20thed.302,AKKhuranaophthalmology2nded:26,253)

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APPEARNACEONFUNDOSCOPY

DIAGNOSIS

Bullseyemaculopathy

Chloroquine

Severeretinaltelangiectesia

Coatsdisease

Saltandpepperfundus

Congenitalrubella
Congenital.syphilisLebersamaurosis
MayousBattendisease
Thioridazinetoxicity

Candlewaxappearance

Sarcoidosis

CherryRedspot

NiemannPicksdisease

(Mnemonic:PickMyQTBags)

Multiplesulfatasedeficiency
Quinineamblyopia
Taysachsdisease
Berlinsedema(Commotioretinae)duetoblunttrauma
CRAO
Gauchersdisease
Sandhoffdisease
Sialoidosistype1and2

(Q.185) Peripheryofretinaisbestvisualizedwithwhichofthefollowing:
(a)
(b)

Indirectophthalmoscopy

(c)

Retinoscopy

Ultrasonography

(d)
Directophthalmoscopy
YourResponse:
a
CorrectAnswer:
Exp:

Theindirectophthalmoscopicexaminationisanimportantproceduretoexaminethedetailsoffundus
mainlytheperiphery.Imageformedistrue,invertedand5timesmagnified.

(Q.186) Growthofthemicrovasculatureduringocularangiogenesisisnotstimulatedby?
(a)

IL8

(b)
(c)

Fibroblastgrowthfactor
VascularEndothelialGrowthFactor

(d)
TransformingGrowthFactor
YourResponse:
a
CorrectAnswer:
Exp:

(Ref.Robbinspathology7thed.97)
Importantcytokines
Name

MajorCellularSource

SelectedBiologicEffects

IFN,

Macrophages(IFN),
fibroblasts(IFN)

Antiviral

IFN(interferon)

Tcells,NKcells

Activatesmacrophages,TH1
differentiation

TNF(tumornecrosisfactor
alpha)

Macrophages,Tcells

Cellactivation,fever,cachexia,
antitumor

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TNF(tumornecrosisfactorbeta), Tcells
LT(lymphotoxin)

ActivatesPMNs

IL1(interleukin1)

Macrophages

Cellactivation,fever

IL2(interleukin2)

Tcells

Tcellgrowthandactivation

IL3(interleukin3)

Tcells

Hematopoiesis

IL4(interleukin4)

Tcells,mastcells

Bcellproliferationandswitching
toIgE,TH2differentiation

IL5(interleukin5)

Tcells

Differentiationofeosinophils,
activatesBcells

IL7(interleukin7)

Bonemarrowstromacells

Tcellprogenitordifferentiation

IL8(interleukin8)

Macrophages,Tcells

Chemotacticforneutrophils

IL10(interleukin10)

Macrophages,Tcells

Inhibitsactivatedmacrophages
anddendriticcells

IL12(interleukin12)

Macrophages

DifferentiationofTcells,
activationofNKcells

GMCSF(granulocytemacrophage Tcells,macrophages,
colonystimulatingfactor)
monocytes

Differentiationofmyeloid
progenitorcells

MCSF(monocytemacrophage
colonystimulatingfactor)

Macrophages,monocytes,
fibroblasts

Differentiationofmonocytesand
macrophages

GCSF(granulocytecolony
stimulatingfactor)

Fibroblasts,
monocytes,macrophages

Stimulatesneutrophilproduction
inbonemarrow

(Q.187) LDHinaqueoushumorisincreasedin
(a)

Galactosemia

(b)

Retinoblastoma

(c)
Glaucoma
(d)
Gyrateatrophy
Your
Response:
Correct
b
Answer:
Exp:

TotalLDHactivityinserumaswellasaqueousismuchhigherin
retinoblastomacases.

(Q.188) Downbeatnystagmusisseenwith?
(a)
(b)

Alcoholism

(c)

Pontinetumor

(d)

YourResponse:
CorrectAnswer:
Exp:

Chiarimalformation
Mniresdisease
b
Downbeatnystagmusoccursfromlesionsnearthecraniocervicaljunction(Chiarimalformation,basilar
invagination).
Ithasalsobeenreportedinbrainstemorcerebellarstroke,lithiumoranticonvulsantintoxication,
alcoholism,andmultiplesclerosis.
Upbeatnystagmusisassociatedwithdamagetothepontinetegmentum,fromstroke,demyelination,or
tumor.

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(Q.189) WhichofthefollowingisusuallynothelpfulindifferentiatingCRVOfromCRAO?
(a)

Dilatedretinalveins

(b)

Tortuousretinalveins

(c)
Ophthalmodynamometry
(d)
Retinalarterypressuremeasurement
YourResponse:
d
CorrectAnswer:
Exp:

Thepressurewithinthecentralveindependsontheintracranialpressure(ICP),becausetheopticnerveis
surroundedbycerebrospinalfluidinitssheath.
Whentheveincollapsesorpulsates,ICPishigherthanorequaltothepressurewithintheopticnerve.
Thepressureofthecentralretinalveincanbemeasuredbyanoninvasivemethod
ophthalmodynamometry.

(Q.190) Eyelea(Aflibercept)?
(a) VEGFR1antagonist
(b) VEGFR2antagonist
(c) VEGFR1and2antagonist
(d) BindstocirculatingVEGFmolecules
Your
Response
:
Correct d
Answer:
Exp:

OtherantiVEGFs:
MonoclonalantibodyBevacizumab
(Avastin)
AntibodyderivativeRanibizumab
(Lucentis)
AptamerPegaptanib(Macugen)
FusionproteinsAflibercept(VEGFTrap,
Eyelea)
MiscellaneoussiRNABevasiranib

(Q.191) TrueaboutJuxtafovealretinaltelangiectasiaisthefollowingexcept:
(a)
(b)

Telangiectasiaofthemacularcapillarybuds
VariantofCoatsdisease

(c)

MayhaveassociatedDiabetesMellitus

(d)
Structuralabnormalityofcapillarybuds
YourResponse:
d
CorrectAnswer:
Exp:

Juxtafovealretinaltelangiectesia
Aconditionthatischaracterizedbyexudationordiffusionabnormalitiesfromectatic(dilatedand
tortuousbloodvessels)andincompetentretinalcapillariesinthejuxtafoveolarregion
Canbefoundasadevelopmentalorcongenitalvascularanomalyoranacquiredcondition.

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IJRThasbeeninterpretedasavariantofCoatsdiseasebysomeauthors.
SignsandSymptoms:Idiopathicjuxtafovealretinaltelangiectasia(IJRT)comesintwoforms:unilateralor
bilateral.Theunilateralformoccursonlyinmenandpatientswillbeasymptomaticuntilafterage40.The
bilateralformoccursequallyinmenandwomenbetweentheagesof40and60,withanaverageageof
55.
Patientsmaybevisuallyasymptomaticormayexperienceaslightvisionreduction,butmostpatients
maintain20/40visionorbetter.Patientsmaycomplainofmetamorphopsia.Patientsmayalsohavea
coincidenthistoryofischemicvasculardiseasessuchasdiabetes.
Fluoresceinangiogramshowsleakagefromtelangiectaticvesselsandblockagefromthehemorrhages.
Telangiectaticvesselsaremorecommonlyobservedtemporaltothefovea.
Clinicalfeatures:
decreasedvisionsecondarytoserousexudation,macularedemaorhardexudatesinareasadjacentto
thetelangiectasis
Management:
Earlylaserphotocoagulationmaybehelpfulinrestoringandpreservingcentralacuityforgroup1
Group2and3typicallydonotrespondtophotocoagulation
Treatmentofneovascularizationwhenitdevelopsingroup2

(Q.192) Trueaboutincontinentiapigmentiincludethefollowingexcept:
(a)

Xlinkeddominant

(b)

Primaryskinabnormality

(c) Avascularityofperipheralretina
(d) Ocularinvolvementisseeninalmost100%casesandistypicallyunilateral
YourResponse:
d
CorrectAnswer:
Exp:

Incontinentapigmenti
Incontinentiapigmenti(IP)isanXlinkeddominantneurocutaneoussyndromewithcutaneous,
neurologic,ophthalmologic,anddentalmanifestations.
Frequentlyaffectfemalesandlethalinmales.
Extracutaneousmanifestationsseeninmorethanhalfpatient
Dentaldefect,delayeddentition,missingteeth
Oculardefectsstrabismus,nystagmus,bluesclera,cataract,retinalvascularabnormalities,retinal
pigmentation,opticartophy
CNSmentalretardation,epilepsy,spasticparalysis,microcephaly
Ophthalmologicmanifestationsmaybecomeevidentwithinthefirstfewweekstomonthsoflifeandmay
progressrapidlytopermanentvisualdeficits.
Retinalvasoocclusiveeventswithresultantischemiaarebelievedtobetheprimarymechanism
underlyingocularpathology.
Retinalmanifestationsincluderetinaldetachment,proliferativeretinopathy,fibrovascularretrolental
membranes,fovealhypoplasia,vitreoushemorrhages,andatrophyoftheciliarybody.
Nonretinalmanifestationsincludestrabismus,opticnerveatrophy,conjunctivalpigmentation,
microphthalmia,keratitis,cataracts,irishypoplasia,nystagmus,anduveitis.

(Q.193) Whatisyourdiagnosisofthispatientwhosfluoresceinangiogramsisgivenbelow?

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(a)

Retinaldetachment

(b)
(c)

Papilledema
Agerelatedmaculardegeneration

(d)
Hypertension
YourResponse:
CorrectAnswer: c
Exp:

Exudativewettypeofagerelatedmaculardegenerationshowingasubretinalchoroidal
neovascularmembrane.

(Q.194) Bull'seyeretinallesionisseenin:
(a)
(b)

Leadtoxicity
Ethambutoltoxicity

(c)
Chloroquinetoxicity
(d)
Oralcontraceptivetoxicity
YourResponse:
a
CorrectAnswer:
Exp:

Lenticonusisabulgingofthelenscapsuleandtheunderlyingcortex.Thediagnosisoflenticonusis
essentiallyaclinicaldiagnosismadebybiomicroscopicexamination.
Lenticonusanterior;lenticonusanteriorispartoftheAlportsyndrome
Lenticonusposterior;lenticonusposteriorismorecommonthanlenticonusanteriorandissometimes
foundinLowesyndrome

(Q.195) Treatmentofadvanceddiabeticretinopathyincludesthefollowingexcept:
(a)

Sealthetearandreattachtheretina

(b)
(c)

Removalepiretinalmembrane
Vitrectomy

(d)
Exophotocoagulation
YourResponse:
d
CorrectAnswer:
Exp:

Advanceddiabeticretinopathy
treatmentofpdr

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Panretinalphotocoagulation
Medicalvitrectomy
Medicaltherapy
VEGFinhibitorsforPDR
IntravitrealglucocorticoidsforPDR
IncaseoftractionalRD,vitrectomyisdonefollowedbyepiretinalmembranepeeling,
endophotocoagulationandsiliconeoil/intravitrealgasinfusion

(Q.196) Cattletrackappearanceoffundoscopy?
(a)

CRAO

(b)
(c)

CRVO
CMVretinitis
HIVretinitis

(d)

YourResponse:
CorrectAnswer:

Exp:

CRAO
Determinethedegreeofvisionloss(eg,nolightperception,handmovement,countingfingers).
Ocularexaminationincludesthefollowing:
Afferentpupillarydefect.
Performanopticnerveexaminationtolookforsignsoftemporalarteritis.Criticalsignsincludeafferent
pupillarydefect
Cherryredspotandagroundglassretinamaytakehourstodevelop.
Thefunduscopicfindingstypicallyresolvewithindaystoweeksoftheacuteevent,sometimesleavinga
paleopticdiscastheonlyphysicalfinding.
Cattletrackappearanceonfundoscopy
Embolicanbeseeninabout20%ofpatientswithCRAO.
Boxcarsegmentationcanbeseeninbotharteriesandveins.Thisisasignofsevereobstruction.
Performacardiovascularexaminationformurmursorcarotidbruits.
Performasystemicexaminationfortemporaltenderness,jawclaudication,muscleweakness,andfever
toevaluatefortemporalarteritis.

(Q.197) WhichofthefollowingismostcharacteristicfeatureofVonRecklinghausendisease?
(a)

DeformedanteriorchamberwithreducedangleofAC

(b)
(c)

Glaucoma
Choroidalhemangioma

(d) Subretinalneovascularization
YourResponse:
CorrectAnswer b
:
Exp:

(Ref.EssentialsofophthalmologybySamarKBasak2nded.220)
OcularmanifestationsofvonReclinghausensdiseaseinclude:
Plexiformtumorsoflidswithptosis
Thickenedcornealnerves
Pulsatingproptosis(duetotransmittedcerebralpulsationsthroughthedefects
intheorbitalwalls)

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Gliomaoftheoptictract
Congenitalglaucoma

(Q.198) WhichofthefollowingisseenwithSarcoidosis?
(a)
(b)

Bandkeratopathy

(c)

Choroidplaques

(d)

YourResponse:
CorrectAnswer:
Exp:

Angioidstreak
Cataractanigra
a
(Ref.Parsonsdiseasesofeye20thed.201202)
Eyemanifestationsofsarcoidosis
Eyeinvolvementoccursin~25%ofpatientswithsarcoidosis,anditcancauseblindness.
Theusuallesionsinvolvetheuvealtract,iris,ciliarybody,andchoroid.
Ofthosepatientswitheyeinvolvement,~75%haveanterioruveitisand25to35%haveposterioruveitis.
Thereisblurredvision,tearing,andphotophobia.
Uveitiscandeveloprapidlyandmayclearspontaneouslyovera6to12monthperiod.Italsocan
developinsidiouslyandbechronic.
Theuveitisoftenoccursinassociationwithretinalvasculitis.
Conjunctivalinvolvementisalsocommon,usuallywithsmall,yellownodules.
Whenthelacrimalglandisinvolveakeratoconjunctivitissiccasyndromeresults.

(Q.199) ThefollowingisusedinCollagencrosslinking
(a)

Thiamine+IR

(b)

Thiamine+UV

(c)

(d)

YourResponse:
CorrectAnswer:
Exp:

Riboflavin+UV
Riboflavin+IR
c
CornealcollagencrosslinkingisatechniquewhichusesUVlightandaphotosensitizer(riboflavin)to
strengthenchemicalbondsinthecornea.
Indication:
Tohaltprogressiveandirregularchangesincornealectasia
Keratoconus
PostLASIKectasia
Contraindications
Cornealthicknessoflessthan400microns
Priorherpecticinfectionisacontraindicationbecauseitmayresultinviralreactivation
Concurrentinfection
Severecornealscarringoropacification
Historyofpoorepithelialwoundhealing(asindiabetes)
Severeocularsurfacedisease(eg.dryeye)
Autoimmunedisorders

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(Q.200) Munsonsignisseenin?
(a)

Retinaldetachment

(b)
(c)

Keratoconus
Aftercataract

(d)
Uveitis
YourResponse:
b
CorrectAnswer:
Exp:

(Ref:Parson,20thedition,Page203)
Keratoconus(ConicalCornea)
Thisisfrequentlyduetoacongenitalweaknessofthecornea,thoughitonlymanifestsitselfafter
puberty.However,itcanalsooccursecondarilyfollowingtraumainwhichcaseitisunilateral,orin
patientswithvernalkeratoconjunctivitisorDownsyndromeduetorepeatedrubbingoftheeye.
Thecorneathinsnearthecentreandprogressivelybulgesforwards,liththeapexoftheconealways
beingslightlybelowmecentreofthecornea.
Thecorneaisatfirsttransparentandthevisionisimpairedduetomyopicastigmatism.Iftheconditionis
marked,theconical,napeiseasilyrecognizedinprofile,particularlybytheacutebulgegiventothelower
lidwhenthepatientlooksdown(Munsonsign)

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