Documente Academic
Documente Profesional
Documente Cultură
2016/06/01
Nervous System
Anencephaly
Anencephaly is also known as open skull. It is the incomplete development
of the brain and the skull bones. Since the anterior neuropore of the neural
tube fails to close by day 22 - 24, the developing brain and spinal cord are
exposed in the amniotic fluid causing the nervous tissue to degenerate. 1This
is why most parts of the babies brains (cerebrum and cerebellum) are
reduced or missing. This defect occurs during the 3rd and 4th week after
conception.2 It is not inherited but parents with an anencephaly child have a
1 "Anencephaly". My.clevelandclinic.org. N.p., 2016. Web. 31 May. 2016.
2 "Anencephaly". My.clevelandclinic.org. N.p., 2016. Web. 31 May 2016.
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2016/06/01
high risk of getting another child with the same defect. Most babies die
before birth or just after. Anencephaly is caused by a deficiency of folic acid.
3 "Spina Bifida - Mayo Clinic". Mayoclinic.org. N.p., 2016. Web. 31 May. 2016.
2
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Fig 2: Showing the difference between the development of a normal spine and its
congenital defect.
Hydrocephalus
4 "Spina Bifida - Mayo Clinic". Mayoclinic.org. N.p., 2016. Web. 16 Mar. 2016.
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2016/05/
Endocrine System
Congenital Hypothyroidism
Congenital Hypothyroidism is the deficiency of thyroid production in
newborns where thyroid developmental abnormalities occur at any level of
the fetal hypothalamic-pituitary-thyroid axis, thyroid metabolism problems or
iodine deficiency.7
The thyroid gland develops from the buccopharyngeal cavity between 4 and
10 weeks' gestation. During 4 - 10 weeks' of gestation, the thyroid arises
from the 4th branchial pouches and bi-lobed organ are formed in the neck.
Errors in the formation or migration of thyroid tissue can result in thyroid
aplasia, dysplasia, or ectopy. By 10-11 weeks' gestation, the fetal thyroid is
Meena Persaud
2016/05/
Pancreas divisum
Pancreas divisum is a common congenital anomaly in which parts of the
pancreas do not fuse together.
Pancreas divisum is the most common birth defect of the pancreas. During
development, the pancreas that is in two parts, each with its own duct, the
ventral duct and the dorsal duct. The two parts of the pancreas fuse during
development. In more than 90% of the embryos, the dorsal and the ventral
ducts also will fuse to form one main pancreatic duct. The main pancreatic
duct will join the common bile duct to form a common bile and pancreatic
duct that drains into the duodenum through the major papilla.
8 "Congenital Hypothyroidism: Practice Essentials, Background, Pathophysiology".
Emedicine.medscape.com. N.p., 2016. Web. 1 June 2016.
6
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and is divided into 3 layers which are the zona reticularis, zona fasiculata,
zona glomerulosa.10
This anomaly can affect normal development and growth of a child.
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2016/05/
References
1. "Congenital Hypothyroidism: Practice Essentials, Background,
Pathophysiology". Emedicine.medscape.com. N.p., 2016. Web. 1 June
2016.
2. "Congenital Hypothyroidism: Practice Essentials, Background,
Pathophysiology". Emedicine.medscape.com. N.p., 2016. Web. 1 June
2016.
3. "Hydrocephalus Fact Sheet". Ninds.nih.gov. N.p., 2016. Web. 1 June
2016.
4. "Hydrocephalus Fact Sheet". Ninds.nih.gov. N.p., 2016. Web. 1 June
2016.
5. "Spina Bifida - Mayo Clinic". Mayoclinic.org. N.p., 2016. Web. 31 May.
2016.
6. "Spina Bifida - Mayo Clinic". Mayoclinic.org. N.p., 2016. Web. 16 Mar.
2016.
7. "Anencephaly". My.clevelandclinic.org. N.p., 2016. Web. 31 May. 2016.
8. "Anencephaly". My.clevelandclinic.org. N.p., 2016. Web. 31 May 2016.