What is the study design What are the outcome measures of interest Who is included in the study (what is the inclusion and exclusion criteria) How were the data gathered What are the results Which results are not due to chance Could the results have been due to bias a. Selection bias (think about participant selection) b. Information Bias (think about how info was collected) 9. Was there confounding, was it controlled for, how? 10. Assess findings by Bradford Hill criteria a. Biologically plausible b. Strength of association c. Time sequence d. Dose response e. Consistency with other studies f. Experimental evidence g. Specificity 11. Generalisability-Who could these findings apply to?