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10/11/2015

ANATOMYANDPHYSIOLOGYII"BLOODBASICS":(week3)flashcards|Quizlet

ANATOMY AND PHYSIOLOGY II; "BLOOD


BASICS": (week 3)

65 terms by Yayagates

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3 General Functions of the Blood

Transportation - gases, nutrients,


wastes, and hormones.
Regulation - pH, fluid balance, and
body temperature
Protection- from disease and blood
loss

Blood facts

Connective Tissue
7-9% body weight
55% plasma
45% formed elements (blood cells)

Blood Plasma

colorless watery fluid of blood and


lymph.
91% water
8% Plasma Proteins
1% nutrients, electrolytes, hormones,
enzymes, gases, and other materials
that move through the blood

Plasma Proteins

Albumin
Fibrinogen
Globulin

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Albumin

important in capillary exchange

Fibrinogen

essential for blood clotting

Globulin

used to make antibodies called


immunoglobulins

Formed Elements of the Blood

Blood Cells

3 Types of Blood Cells

Erythrocytes : RED BLOOD CELLS


Leukocytes : WHITE BLOOD CELLS
Thrombocytes: PLATELETES

Hematopoiesis

stem cells produce all three types of


blood cells

Red Bone Marrow

where blood is produced in the human


body

Erythrocytes : RED BLOOD CELLS

transport of oxygen from lungs to body


tissues
120 day lifespan

Hemoglobin

molecule in the red blood cells that


bind with oxygen

Hemolysis by the Liver or Spleen

the process where old, worn out red


blood cells are removed by phagocytic
cells

Erythropoietin

the hormone secreted by the kidneys


in response to decreased blood
oxygen, that stimulates the production
of Red blood cells

White Blood Cells

protect the body by destroying


pathogens
remove foreign material and cellular
debris

3 Granulocyte White Blood Cells

60-70% Neutrophils
.5-1% Basophils
1-4% Eosinophils

60-70% Neutrophils - WBC

Phagocytosis -increased with Bacterial


Infections

.5-1% Basophils - WBC

secrete Histamine and Heparin

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1-4% Eosinophils -WBC

increased with Parasitic Infections

2 types of Agranulocyte White Blood


Cells

20-40% Lymphocytes
2-6%Monocytes

Lymphocytes

20-40% of WBC, found in lymphoid


tissue, small percentage circulates in
blood, key role in Specific Immunity

Monocytes

2-6% of WBC, Phagocytosis increases


with Viral and Chronic Infections

Neutrophils & Lymphocytes

Account for the Majority of White Blood


Cells
Neutrophils 60-70%
Lymphocytes 20-40%

Phagocytosis

process by White Blood Cells destroy


Pathogens and remove foreign
material and cellular debris.

Neutrophils & Monocytes

2 circulating WBC's engaged in


Phagocytosis

Macrophages

when monocytes enlarge and mature.


essential to the immune system and
found in the lymphoid tissues, lymph
nodes, tonsils and spleen

Platelets

smallest formed element. are not cells,


but fragments released from bone
marrow - essential in blood clotting
/coagulation

Megakaryocytes

Giant cells in bone marrow that release


platelets

HEmostasis

process which prevents blood loss conditions - Blood Vessel Spasm:


Formation of a Platelet Plug: Blood
Clotting

Blood Vessel Spasm

smooth muscles in the blood vessels


contract to reduce blood flow causing
vasoconstriction - reduction in the
blood vessels diameter

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Formation of a Platelet Plug

activated platelets become sticky and


adhere to the defect form a temporary
plug

Blood Clotting

coagulation

Agglutination

condition that cause clumping of red


blood cells and antibodies in plasma,
due to mismatched blood transfusions

Type 0 Blood

universal donor - contains neither A or


B antigens

Type AB Blood

universal recipient - contains no anti- A


or anti-B antibodies.

Anemia

a blood disorder where there is an


abnormally low left of red blood cells
or hemoglobin in the blood which
impairing the delivery of oxygen to the
tissues. weakness, fatigue,
lightheadedness, difficulty breathing,
cardiac palpitations and headache.

Leukemia

a cancer that infects the WHITE BLOOD


CELL Tissue. bone marrow or lymphoid
tissues. extreme increase in WBC that
are immature and ineffective which
severely depress the immune system.
WBC take over the RBC causing
anemia, and bleeding problems.

Myelogenic Leukemia

cancer of the bone marrow.

Lymphocytic Leukemia

cancer of the lymphoid tissues.

Clotting Disorders

conditions characterized by an
abnormal tendency to bleed because
of a breakdown in the body's clotting
mechanisms.

Thrombocytopenia

a decrease in the number of platelets


circulation in the blood. most common
blood disorder

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Hematocrit

Red Blood Cell count test expresses the


percentage of Red Blood Cells in a
volume of blood
below normal result = anemia
above normal result = polycythemia

White Blood Cell Counts

below normal result = Leukopenia


above normal result = Leukocytosis

Platelet Counts

below normal result =


Thrombocytopenia
above normal result = Thrombocytosis

Complete Blood Count - CBC

RBC : Red Blood Cell Count


Hct : Hematocrit
Hgb : Hemoglobin
WBC : White Blood Cell Count
Diff : Differential White Blood Cell
Count
Platelet Count

BUN Blood Urea Nitrogen

test to determine renal functions -

Urea

is formed in the Liver and is significant


nitrogenous waste product from the
catabolism of protein for energy

pH

is a unit of measurement that indicates


the number of hydrogen ions (H+) in a
solution.

pH Scale

0 to 10
7 = neutral
below 7 = acid (more H+)
above 7 = alkaline (less H+)

pH in Plasma

range from 7.35 to 7.45 average 7.4


less than 7.35 is acidosis
more than 7.45 alkalosis

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Regulation of acid-base pH

1st: Buffer systems, primarily


bicarbonate - regulate chemical
reactions by removing/adding H+
2nd: Respiration - a decreased in
respiration rate decreases pH by
retaining more CO2 an increase in
respiration increases pH by eliminating
more CO2
3rd: Kidneys regulate pH by
reabsorbing or excreting H+ as needed.

Vital Capacity Test

Pulmonary Function Test - PFTmeasures maximal inhalation and


exhalation. It is a measure of airflow
function of the lungs. It is used to
monitor the ling function of patients
with COPD

Urine Test

Specific Gravity measures urine


concentration Urine color Test - straw color to amber
Urine Odor - non-offensive
Urine pH - normal is 4.6-8 avrg 6
Turbidity - clear to slightly hazy
Sugar/Glucose - <0.5 mg/dl
Protein (Albumin) - 50-80 mg /24 hours
Ketone Bodies - Negative
Bacteria - Negative

Fecal Testing

Amount :100-200 g/day(3.5-7 ozday)


Consistency : Plastic
Form : Soft
Shape : Cylindrical with the same
diameter as the colon
Stool pH : Neutral to Slightly Alkaline
Stool Color : Brown

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Blood in Stool

-- 2-2.5ml of blood is normal to pass


into the GI tract/ 24 hours
--More than 2.8 ml indicates some type
of GI pathology
-- Excessive surface blood indicates
hemorrhoids or fissures
--Occult Blood (hidden) indicates
bleeding in the upper GI tract
Normally there is no mucus in the stool

Electrocardiography

ECG/EKG - produces electrocardiogram


which is a recording of the electrical
signals of the heart - diagnosis
problems with the heart

Echocardiography

produces an echocardiogram which is


a test utilizing ultrasound to give a real
time 3D view of the functioning of the
heart

Holter Monitor

portable EKG for 24 hour monitoring

Stress Test

EKG during progressively increasing


physical contact - determines the heart
function while under stress

Endoscope

device used to look within the body

Otoscope

used to examine the external ear

Bronchoscope

used to examine the lungs

Gastroscope

used to examine the interior of the


stomach

Laparoscope

used to examine the abdominal region

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