LS3-1, W09

C. Lin,

Life Science 3 (LS3-1)

Introduction to Molecular Biology
Winter 2009 (January 5 March 17, 2008)
Instructor:

Chentao Lin, Ph.D.

Professor of Molecular, Cell & Developmental Biology
Office: 3317 Life Science Building (LSB),
Phone: 310-206-9576, email: clin@mcdb.ucla.edu
Homepage: http://www.mcdb.ucla.edu/Research/Lin/

Lectures
Office Hours:
Textbook:
Course Web site:
Bruincast

MWF 2:00 am - 2:50 pm, LaKretz 110

MWF 3:00 am - 4:00 pm, LSB 3317
Molecular Biology (4th Edition, 2008) by R.F. Weaver.
http://www.lsic.ucla.edu/webapps/login/
http://www.bruincast.ucla.edu/

Exams & Grading:

Laboratory:
Midterm I (Tue. 1/27, 5-6:50pm, lectures 1-8)
Midterm II (Tue, 2/ 17, 5-6:50pm, lectures 9-17)
Final (Tue, 3/17, 6:30-9:30pm, lectures 1-28)

100pts
100pts
100pts
200pts

20%
20%
20%
40%

Lab & Discussion Sections: Discussion sections (wk 1, 3, 5, 7, 8) and Lab (wk 2, 4, 6, 9, 10)
will be lead by Drs. Gaston Pfluegl (Gaston@lsic.ucla.edu, 794-4113), Rhonda Murotake
(rhondam@lifesci.ucla.edu, 825-8860), and your TAs. See the LS3 lab manual for details.
Honor Section (LS89)
A honor section will be offered for the LS3-1 students who want to learn more about Mol. Biol.
In the honor sections, research papers cornering a specific biological question will be discussed.
LS89 will meet in LS3326, Friday, 4-6pm, starting week 3 (1/23/09).
Teaching Assistants:
Mariam Aghajan, maghajan@mednet.ucla.edu
Hume Stroud-Drinkwater, hstroudd@ucla.edu
Jenny Hernandez, hernandj@ucla.edu
Mary Clark, clarkm@ucla.edu
Shawn Jia, shawnjia@gmail.com
Minglei Zhao, mlzhao@ucla.edu
Genaro Villa, grvilla@ucla.edu
Administration:
Life Science Core Curriculum Office (LSB2305, Lily Yanez,
lyanez@lifesci.ucla.edu, or Mark Katayama, katayama@lifesci.ucla.edu) will address all
administrative issues.

LS3-1 (W2009) Syllabus

Week

Lecture

Monday, 1/5/09

Introduction

Chapter 1-3

Wednesday, 1/7

DNA and genome

Chapter 1-3

Friday, 1/9

RNA and Proteins

Chapter 1-3

Monday, 1/12

Molecular Biology Methods

Chapter 4-5

Wednesday, 1/14

Molecular Biology Methods

Chapter 4-5

Friday, 1/16

Molecular Biology Methods

Chapter 4-5

Monday, 1/19

Martin Luther King, Jr, Holiday

Wednesday, 1/21

Molecular Biology Methods

Chapter 4-5

Friday, 1/23 (lect 8) Molecular Biology Methods

Chapter 4-5

Monday, 1/26

Prokaryotic Transcription I

Chapter 6-8

Tuesday 1/27/09

(Midterm I, Lectures 1-8)

5:00-6:50pm

10

Wednesday, 1/28

Prokaryotic Transcription II

Chapter 6-8

11

Friday, 1/30

Prokaryotic Transcription III

Chapter 6-8

12

Monday, 2/2 (PO)

Eukaryotic Transcription I

Chapter 9-13

13

Wednesday, 2/4 (PO) Eukaryotic Transcription II

Chapter 9-13

14

Friday, 2/6 (PO)

Eukaryotic Transcription III

Chapter 9-13

15

Monday, 2/9

Eukaryotic Transcription IV

Chapter 9-13

16

Wednesday, 2/11

Eukaryotic Transcription V

Chapter 9-13

17

Friday, 2/13 (lec 17) Chromatin structure and Transcription

10

11

Date

Topics

Reading

Chapter 9-13

Monday, 2/16

Presidents Day Holiday

Tuesday 2/17/09

(Midterm II, Lectures 9-17)

5:00-6:50pm

18

Wednesday, 2/18

RNA processing I

Chapter 14-16

19

Friday, 2/20

RNA processing II

Chapter 14-16

20

Monday, 2/23

RNA processing III

Chapter 14-16

21

Wednesday, 2/25

Translation I

Chapter 17-19

22

Friday, 2/27

Translation II

Chapter 17-19

23

Monday, 3/2

Translation III

Chapter 17-19

24

Wednesday, 3/4

DNA Replication I

Chapter 20-21

25

Friday, 3/6

DNA Replication II

Chapter 20-21

26

Monday, 3/9

DNA Replication III

Chapter 20-21

27

Wednesday, 3/11

Genome structure and genomics I

Chapter 23-24

28

Friday, 3/13

Genome structure and genomics II

Chapter 23-24

Wednesday, 3/17

Final Exam (Lectures 1-17)

6:30- 9:30PM