Basic Medical Sciences Course for TCM Practitioners

General Pharmacology
Quiz 1
Name:

I/C No:

This quiz consists of ten (10) questions. Select one single best answer for every
question.
1. The following are part of the pharmacokinetic process for drugs in the body,
EXCEPT
A. Absorption
B. Distribution
C. Action on target organ
D. Metabolism and biotransformation
2. The main advantage of oral administration of drugs, compared to intravenous is;
A. Better absorption of the drug
B. Better distribution of the drug
C. Prevention of first pass metabolism
D. Relatively cheaper and safer
3. Which of the following is a parenteral route of administration?
A. Oral
B. Rectal
C. Subcutaneous
D. Sublingual
4. The following is a limitation/precaution of intravenous injection of drugs
A. Poor distribution and bioavailability
B. Must be administered slowly as a general rule
C. May only be injected once a week to avoid side effects
D. Not suitable for drugs that are soluble in blood
5. The following affect the absorption of oral drugs, EXCEPT
A. Surface area of the gastrointestinal tract
B. Blood flow at the area of absorption
C. Concentration of drugs at area of absorption
D. Ingestion of the drugs with plain water

6. Which of the following drug absorption methods uses energy?

A. Passive diffusion
B. Facilitated diffusion
C. Osmosis
D. Active transport

7. In first order absorption kinetics;

A. Rate of absorption is proportional to the concentration at the site of
absorption
B. Rate of absorption is independent to the concentration at the site of
absorption
C. Rate of absorption is proportional to the temperature at the site of
absorption
D. Rate of absorption is proportional to the concentration at the site of
excretion
8. The following determines rate of delivery in drug distribution, EXCEPT
A. Cardiac output
B. Capillary permeability
C. Tissue volume
D. Severity of disease
9. If all the carrier proteins for a particular drug are occupied (saturated);
A. More unbound drugs (free form) will be available, hence an increase in
action
B. Less drugs will be absorbed from the gastrointestinal tract
C. The dose of the drug should be increased to compensate for saturation
D. The drug should be given intravenously to increase binding to carrier
proteins
10.Half-life (T1/2) is defined as the
A. time required for a drug dose to be fully effective during treatment
B. time required to reduce the amount of drug in the body by half during
elimination
C. time margin given for a drug to act safely without side effects in the
human body
D. time elapsed before the risk of disease is reduced by half