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GHID DE FARMACOLOGIE PENTRU ASISTENTI MEDICALI st ASISTENTI DE FARMACIE CRIN MARCEAN VLADIMIR-MANTA MIHAILESCU (GID DE FARMACOLOGIE PENTRU ASISTENTI MEDICALI $1 SISTENT! DE FARMACIE Cin Marcesn, Vladimir-Mante Mihilesca Copyright© 201, 2012, 2014 Eatura ALL rol DEGRINMARCEAN De VIADIMIR-MANTA MIMATLESCU [ Desciera CIP aBibliotecif Nalonale Romanist -MARCEAN, CRIN (Ghd de farmacologie petra assent medical aistenti de farmnacie/ (rin Marcean, Viadimie- Manta Mibalesc,~ Bucuret: altura ALL, 2011 ‘bog. ISBN 978.973-571-579-1 [Mihilsc, Vladimir 61500758) J GHID DE FARMACOLOGIE ‘Toate deprle reervateEtuil ALL. pentru asistenti medical gi asstenfi de farmacie ‘Nici parte din acest wolum mu poate cola ‘rk permisonen sexist Elta ALL. ‘Deepurle de divtrbut in stinitate sarin tn exclastitate eit Allright reserved, Te dstetbuton of this book outside Romani, without the writen permission of ALL i strily prohibited ‘Copyright © 201, 2012, 2014 by AL. alturs ALL: Bd. Constrctrior ne. 208 sector 6 cod Q60512~ Bucuret ‘Te:021 4022600 | Fax: 0214022610 eartamentalditcbupie: Tel 021 40226 30;021 4022633 | Comencile: —_comenziallro sora Redactr: De. Blanca Vase ‘ehnoredactre: Livia Stlca Covet: Mihaela Violeta Dumitra Design coperti: Alerandra Nowe | CUVANT INTRODUCTIV A sci un ghd de acces pres mun sib tn nt i vil dell ace persons sno sje cf pg dein se pabolovanal eareserosiogen din outn al test macs eb lade Bincpa desc ae deo fk pts termina. Un stemenes seenari poste Bexapat in let, crrea deme pcre Tam batt Pst at de apie gd nar wet progres in domenl ‘Hine mediamenflt inca as terion apt iil dj ap ftenood rap ao nou gnerabe de en tempetldtiatn no produces ns pe pa Smart, descnpest ok prop le {oer subeny-a deseronele rea aden ncn ple pent “Amconerpa cs hide faroesoge conform carl in got et tw nla posed santa, pnts aie mela general dae eve sen mae tind a dim o rte prt pga L Loctres et strctart pete sens, previnte xsodle nan de ‘avant 1. GID DEFARMACOLOGIE GENERALA 2. GHID DE FARMACOTERAPIE 3. GHID DE FARMACOTOXICOLOGIE Devin ex hil elma vitro een mel asst de {armace am aor un pf nal e~ ane redo atl cet - pe i generale La schimb, a cosieramporant ent aivises perl Tatmec-sntar am dat mal rare devote ia ele programa de laviindat ~ indie de ile contrandetr eor de administrate Stele adverse, cae unto pa atten ei visa blown pe Fea: Det cu sal de a conten eno i a ote nein de bk ale acest die dar meses mee a ps sh sul cent pe ceca ce aie medal sist de fami ol in mans lor inept cu mediante, dec pe formar se vai teoretce nh dar mal pu pia Din aces mot, ecunea GHID DE FARMACOTERAPIE aps caro mare putea volun, (A NANCE, VLADIMIR ARTA MIA In eptrt ca orine eptselr din seu GHID DE. FARMACO- ‘TERAPIE am conierat neal modicar nde pan cade al oxi ‘mantld aemacaog,aoptnd o staan pragma ood node ‘AL A float in eal mare partes aera ices AT (Arata, “hepa Chal Cafeadon Stam) spats de Ora Mondals 2 Sitges ans nomenenorle de meierene df nowt dln ati Evtnd stl enamerces arr deter dase grape de {nedcament, casera relent vsne ord espe sae gamed ‘Soe trap de tote ere (eaves emote eine), Se ecade “SHG, o pecepete ole a ace imens omen se pate fice med ‘adie ocr agen terapete now ape a apo rela pine ea opr struct u Ta plo ale per tote ole (onde cod ‘le sbud®), meicamentle au cpt ee cod lo, fp care aliens ‘Suse rc! subne~ pin splat a end = ds, grup ‘abgrapa rapt dn ue fae pte, pein compara cu subtafele Invade, ex ese agonist antagonist Ton peta ca eta voluma ‘preci eine mest acd sf tn tex a dale [NTC nu fst iat ora cle gop portant Atagem seni ck ic a unele aptle teri reetat dpi cada sti al programe ‘nlc, am Ret index tun mana Indep ete 0 sud {informe desis ok ispands ier (ager, previ) cast ota cre stud Am ct, tle of antici dora neva ce Info itoro, fe ot et seni medial, ssn de armale sab ua prtesoat! ‘Urmiodexenpa anor lc depot din ale a intrdus wap spre pode bilge late In erepetcs anaes sera heterloge, lnmmoglie mane peti vccns cla dae acs pode un rtd omen ctrl de medicament propria ni Ameer de ctu Fate i consei am crest an capt separt despre ogres 9 aco leg de eicomant care fometat blct de stad pena fama Colegiul ptr serviced psa. \ Tcl ce cpt nero cnopnle pce tn mod pei seaeriatadtelor mela st moar ole nate lor medal atria moajlor at nla mean od se [sie de frac x formal fate ator de forma’ tel Inc prin sroctrs coon sb, maa fe ul umbelor catego. (Gade dee dea trode doa ghd de pepti, pst din ‘one «ono prepare ner (ete vorb de roduseantinfcone de ut stone necube- exp 15g de ace ejecta cap. 7) 8 done ‘otek inactvata paced aviteardr ede medico sunita Not important Cale AT, aml din abl ne de smut denise pein ounce denn oink ‘icant NU wtie eort cua cate tte errs ‘complicate detaees spun dn tte prea aos ‘Ere cu cop det ml ot it el iris ‘nme tnlneer loune + ade especie CUPRINS ‘Abreie snob sate een 1S SPCTIUNEA . GHID DEFARMACOLOGIE GENERALA. 1. Nef tod 1.1: Domeni principale ram ale anmesogi nro 12. Caeaten ATC 1.3. Papa forme mace ate eer dima) 24 14 surge onto ptr nedaentt ee 30 15. Farmaco dapat ermal homeopti ne 31 16. reserpine asiterlar defarmacio— 31 17. Nomenltrsmediementlt nn nem ey 18. Grope portant de substan nt farmacoepic it tonelogie eee 2. Farmacocinted generale 3? 2.1, Gite deaminisrare aber mediate 37 22, Disuibua eines medlnmentsle in ogame #0 23, Metiolare leprae medicaments 2.4. Timp de lt never 25. Dorarea median event 5. Ghidde admintareumeicamenion (te sister medal) ‘ML Repl gma 132 Admire mecaiensor dew stem 6 95 Admiitire medcamenlar ew tpi eal) von 2, Administ ttmentaat in nil pale 8 4 Furmacsoge molecular ft faracodipmlermnennseronmns S {i Famacorcepio nnn nen 42 Atal 463. Ttanerl en membrane nee (CUS MAK, VADIR ATA MINAS |, Neurtansmiten (mein eit) engeno TB ‘5 Meet tema nervos eget SNV) "SS nerves simp (otaript) = mena aden 76 132 Seal prsipati~ deni iene BS 38. Siang pang nen “SECTIUNEA A IFA. GHD DE FARMACOTERAPIE.~ 6 Medan aareaa ity (61 Mediated antlers. 6, Peper cu eonime gestive (408) {8 Metleamente penta fection eptle [A 05) — 7. Madiamente petra bol de mats st metabolism. 721 Medcameste uted 8) 372. Medieamente antiabetice (A 10) 73. Media hiplipeniants (C10) vo 7A Vitae em 1.5, Sobran ner [A 12) 7.5 Pods pene nti clined eater 279. Sol em pene ati amen) peel tndovenoaed (B05 BA 17, Antonia ql upimene mente 19 1 Medea singel ‘A Prot eatnenn, {42 Masai athemoreie [B 2B] 83. Antitrmbotie [On {U4 Prods destatede sng [805 AN] 15. Soli macromoleclare rebtinentede plat (pein exande" (B05 AA. 93, Medicamenteantaric [C01 Bn env AB 94 Vasaiatatoarcorpaiene [CO D) enc SD 9.5. Nadas nthipeenie [Coes =r Cscarea medicament sthiperensie dap mec de ace an 10. Media dermatlgil Forme ume se mica de ape Tndermatcoye (toa aed fart) cD 104 Medsament sntinfrose Gee dematclope (ples) [01D 6) nnn NS 102.Cortensteroi dew tpi ca [DW] nm NS 10. Antsepie devinfctante paz pe [DOH] 165 10 Prepare peters lee al pe [D0] wromvvoo— 186 1. Media peal ria eT) 1. Diattie (C03) 12. Antepastee nae [G06 BD]. meen 1 113. Atiissice urine [G04 BC 606 BX} 70 12d sparta gent feminin (tater mong nm 1 121. Medien ntfs de waecalgeclogle (G01 Al e171 122. Apo ode ¢apen tcl, mm 1. Hormonl eral edie contacept 175 1344 Conmaceptve hormone eis [G3 1H. Mormon! penta admits ste. 14, Hormoni hpoes ihipotalait 501] — 142 Corcnuralt de ster [1 €2 wer 143 Harmen oii! (1 05 Alanna 144. Anthormei eden! [103 Bo 143 Hormonl puna: [105 A) 146. Ahhormoni paratoien [205 BA 147, Honmoni pancreatic 04 emer 15. Produ antnecowse de wei. 15.1. Agent ntmrobienl (atic Ff) ee 182. Tabercloste 6A m0 153. Aatifiungie (atime) ora 0 1544 Antec dw semi 05 ‘Ghd de prep, pare adminserc nor produce sninfeone inet (toa aseor medial) 16 Prous lai flste pent maize. 16. Imanoglbuline wane 0684). 162 Vac [Oho 17 Anineopasc (medicament ancanceraa) 2s 171. Gosate (usaf ete) LO] 28 Mecanimele eer acne le ction — 288 Prince tone atest farmer fmattaologl on ee 172.Ghid de prgitie, pst dminares uno cote ejecta (natn iter ea) 258 173. Masur de precaueis ers carl de chimp 964 Ce 18 nomen nn 18 Ao imunostimalitoel 03] 182 Imnonupese [LO4) ene 19. Medica part ocomtat nn 194. Meda antieumatil von 192 Saban merdaeateperierice (curred set) (903A) 193, Medici eteopororel in alor cask ‘nne derleete [M0], 230 Aneseie pl amalgei 204, Aneseie peal [D1 A. 202. Arete eee [NOE B) 203, Analg oplolde N02 Aj 204 Aralgesceantipeic[NO2B) 205, Pode impr igen [N02 Conon 21. Mezata woo bol pelo mn 2.1. Medina nile (N03) ‘Rega miss de preci cal wataent npn arisen meal. 21.2. Media stiplinoninn (NOM) 213. Media anvertigo N07 Ca = pater 25, Sbstantaniparntare nsestcie. BB. Protonode [OI 232 tiene [P C2). 233. Eaoparetcd (PO) 24, Mella apart expat 241. Expecoane [ROS CA] 242 Mieaiies [R05 CB] ccm 243, Ams 05D) 244 Media tite 25 Alege enn = 252. Antisainie dr ste [05)_— = 2% Mean organo sent enn 261. Neda ofall [S0)— i 282. Media flog S02. - 2, Deanfecanteanteptice 17. Dennett dew elke 272. Deegan nan RL Medina opine 282 Medina vail nor ‘Medians alten mod cuentin grog gene. 36 SECTIUNEA A II-A. GHID DE FARMACOTOXICOLOGHE.. 29-Elcte ale meicamenilor in cs sca ligt nate moazlr 399 28.1. Foc decal medicament curl tla 339 292 Vaccine In sal suena nr \ 293. Mediamentein pends Sapte ‘M.Ren adverse (fete secundar) ale meicamentor in etefia estore wma = 2. Rec adverse pein Hosni 12 Reach advene pin fete tance 33. React adverse prin meen lis 3. Interac icmp medicament. 31 Mediamente alto aoc este containdinh vo 357 312. Mediamente are prin ascere ura modi Me C0 een 52. ates oe sn 3 "3 Intnl cu dierent nc medina) on 3 a ae [33 Gh detratamen lorie cate prin ingeare {in gener ofa etre nem 38 2. Drogut pent area nn Si es eal 232Dropricescjne derma rapa Gehl ero8 Aten 33. Drogr cx cine islet espe [Sha ere centile 3B 334, Drogen. —veen =n ane {5 Dilete aedogut ves 0 een ABREVIERI $I SIMBOLURI FOLOSITE IN LUCRARE ADH (Anihrtie ormone ng) = hrm nsec - herman ‘creat de hipoulumus toc! in nds hpofedpostiar,d unde ete ‘Sibert peintrun mec de ecbck, Ae actage stricted zor ae tn bl conto tl ail elector din nih 'ADN = oid de(nibonuclse (DNA ~ een) = ai ale x l= al land fom ister ou aj Ing) loi pl), comput din pumeroare anit de mili, Aces sant lube ecre finite prince (adenin uti) ane prince (ctv tun), penton deloxisbor] aed fosfve. ADN-al exe tril dia ee se ‘eemeas romesam parol gear as mpi crate rar le rgmisneloe 'AINS = anasto neteroiene Din sent ci de mediamente ‘acepereajortes medicament eeu cusp oricte ror: ainsi, didefna,indemetacnbupaen ee ‘Al slumisu dlameat chime meta it ub orm de ru i merase malcamente alert. ‘ALT= lni-aminoateral ~ st esimate delabrator pet fui hepteInhepattel sete ae vlna cece in bec er demu Tarmac. 1 ARN = ci bone (NA ~I el) 2d mace cu molecu iat monster avid componente ssemanitoare ct ADN, da ee cine ‘ou local defpoceoaet ral noe de iin, ARN des fer ‘re protineo din cele, apt program iscsi col pei [AST =asperat-amintalrat tet ensnatic ert pest fn iaheptc le hepatteae valor ml reset in sates deni TGO sas on. ‘ATC (Antonia, Tepes, Chol hen) - clara matic mec dpe in rine acest) enrol, tapeue cic "AL =szivenirelt, cn banceany, uapioug nora MAREE (ceca —set ies fore espe el epi gin dee mediate {CaCl done eats uanun ae -prput meet aa cre meen so pers ba sms ee) ae 8 ane ah in gene “cs do omen china crc eet trad in compan de feces neha de rr ends O9W Cer Fulogie yn sa ‘rh rode S30 ole lr hipero) slide ora de feta 745% lupe ole Rpero), in solange Sr pests ‘Eiaare or (ORS = Ora eatin Sth enh {CY = comeplovice snl ae pode come, tone sigma Sn le es we aml he otha cena WWW =n Wal inne be ogl sa cada ie eet creer ne ECS) wn he= dona nd n compen we pus gy gtr Mek nde Meh ol) = mas eit come ean coer hl apa) wr mde as Pfepanma p ants dt te pip col AC, pn xl sae sup iron il ce Der uj) ANauGteice OmoMDE(ND Aut bats Seven SECTIUNEA I GHID DE FARMACOLOGIE GENERALA 1. NOTIUNI INTRODUCTIVE Deine suexeuicaTIE Malice sitencd » melee caine le distant supra ana unt organ so ster aus nani (Bose es or, ‘porioaele cle injectable Lm x) None pas et mai ly ce cae anes oe ‘Prparateglonze = prepare famaceatce standard cbjaue din plate su sbsane mineral eae septate ca stare (0 singar eet a) ‘Sin dlrte combina se medicament Se presi ea poles ens, ‘omprimats pl; extrac aide nolan lide; ung, ceme spe ‘ol pease hirealoaice a ceria opr ofan cei ine ‘er ltr eine, maclagh (tet ais ara prep ie (ese Tip = ne meen a iit not 11. DOMENTUL §1 PRINCIPALELE RAMURT ALE FARMACOLOGIEL Farmacolgi ten cree cop cx origina medicaments tara log stetira cn, talon sfrtetnoraiem,meeniemel dear tne. eft benefice noc preci moda eile sor in acti Dace. Ea cupnde a alert cre tdi sxte dere sper, ans MARCHA, VLADDUR MANTA MEALS Farmacocneia soc i mje (eet) medicament nog tm, abnb, export ueearea pin membrane, dsb in fee ear ogee, em de cine, btanstormide (metabelian dkeyadarea),precum eliiaure medicament (elem de elisa). Tarmacodinamin set acunes mediamectlr supe ltl ‘stor rane inteacgune lor or cep pei; dtemina exper ‘ena lorlymecnimcle ave saa ane entre snd cle profes do reticent organ, Tarmacoepidemiloia re rept ole tcl de medicament te 2 entindsle medicament, pec fetepoie de olay cae ot ftratecu anual geo teapete. Farmacopenein fe sp de iil re tr eet apa (cecil etde medrese "Paracognoci die xe, propre ie chime 9 prepa ‘are medicament de ogine vegetal elma sr mer. Est ora eco de imports pent indus freer armacopralarcepar) preter foes de prezestarea medieamen- ‘og ste repuie¢ mole depres alr. ‘Farmacolois molecular se cap.de meansmeleatine de mare fee incre acinees agen teapet! famume lanl de orga ele, ‘ceptor gleaale membrana, snaps, ezine, seme metgeesecundare, Seed dlertlor metbelame te Tarmacoterapn ae dropt oie (lara mudeamento in practice tl olarl lee egle nel etmple ecamands terapetice Infante edt despre fies bola, Tarmactoriclogia se onip de real tere (late ecandar ne oct) ale ecamene poem ide imositilemediexinetoase ater Inara! indole se opeedvii. Farmacovglena (ren vec al pin tit) te deni at ‘ates rin ere rate vere fet oie le madiesmenlo nt ine ger canoes, imprean ca miloure de preven sett oe, ‘lfarmacetiea (beg Bopharmaces) se orp de rele in tre propietieilo-dhmle ale neato acitatea lor Bogie. “Treble subliniat ct formele cristalzate sou amor, mkrimes particular. na rexcplentula metodel de abricare sera absorbs, bodspen tae chiar etbozace aetunelr nora. Palofarmacoloia cx damental gen erspentics foe bolle tubustlepstice(maeamentelepsotrpe) Touieologi= isjacare radia rattle cata sngtomtlola Acar tect pment decombutere ae nly aniture) Are Tepiurco medina els erin, 1.2. CLASIFICAREA ATC (Anatomical, Therapeutic, Chemical Classification Sytem) ‘eo lsifeae mute a medicament, cae perm sue tro ‘categorie eer produ lat i sco terapesti on not along ‘ele te crite mena a denunie (anton terse chin). Ce ears liane an est do exprare odie, abit conven ad- ‘nis frustrated pecs [NIVEL aratt up anatomi (paras ster ae sex ese expat oar nl, dpa cum aren “AC provine Gln Alimentary ac and measly) ~ copra mdi ‘eaertl per tte segue ate para diy pec PC ‘cl cae se adresee olor tuber metal de nate. A wt Inds ate dpe de nie vance 'B (del Blood and od foming oan) iacade medicament wise ta oe sge x opeor hematopoietic, eceptnd ctor ulate emopaie maligne U ‘(dels Cardoesuer tom) -copsnde medicines inn ci cali! parece (dela Dermatol) copie medial de pein ante oi, trode panini deus oa 1 (dela Gentosrinary prom and ex hrm) - apne medlameste ptr fine spar uriay sl apartl ental marin fain Cnc penta tratameteaninfeoae lel), pram heron ‘exull pent abel re NU cone madcamete fore Io ater ‘Shemial bollr ca tanner esl Ble ener) 1H (omic hormonal prepartion, edn x hormone nd sles) socop de repartee hormonale eacepind hoon seal [9G in salina Al nt neti for steric) ~ caine chimp nbs a ‘iro, antmiaie,taberelatie, se ne in oe de admits sistem, Cle dewzloal 3 AD #6. ‘L mieoplatie and immunamddtng ent) ~ alae tse nmaosuperele 1M (Gea Musculatelaa tem) - confine nediamentle andreas, alec bal encore ale bllor muscle ‘(Gel Nervous te) nce tte moment ct sarees ‘ex ros cents ero peers never esta. (Antares roduc, ce and replete sane paar sete repinatoar de nt ch anezay, Uap RAIANTA MITA 1 (ee Repintory sate) ~inule medic pena txt segmeiele sparta epraoneceptind anode infil oper re ster [> J} At un incase lantistaninete de we item: "Sele Souory organ) copa de adres anlztoull aul (oreprteoflmeloie ce pet analiatorl od (rose blog. ' dels Various) cone adc, agne tet ptr baler, produse dec, produst stonutloge avenge Asan. li (a aaj) conta pet eamenle nope (alg CT, RAN, exe- ne ca luasanee (ogni, enmene ea pei) "X= cupinde prodrespterpis (pe bad de mee, terete ee ‘us ate produse vegetal) prepare homenpate. [NIVEL at enolic ina rap rape peal gon ‘et Tnadligae dou ie empl ‘Roster hepa Nas Anges NIVELULl Lal cod sl pe sop type rms teen pin sdapres unlit Eel tire ea a) ‘AteA~ Texpeb, Bg A Peps NU2- Astemie ete, DMIVELUL al Vea syrup into api rng co ‘sip else Eup Gotten corde ele eee) ‘AGS AA™ Paparaciii ‘BOSAA Prepare ca ferbalent ole, [NODBA~Detna eed tae NIVELUL ¥en cou bea pe subrop chink ioe capi pin doce nents seg Exel ere c) TAG AAGT- Acteseodemcce ‘ 1.3, PREPARATE $I FORME FARMACEUTICE : (tn atenia asistenilor de fermacie) 1.3.1. PENTRU ADMINISTRARE PE CALE ORAL ‘Preprate forme) farmaceutic slide Capua cae dean pverlent seh et cont = un mice sl (one cup, eat in aon peli sa che- un. Capsule enteroseuble (gstroenstent) sunt denne se diava ‘nunain nei nd tel teen tome as acres eiamey {olin stems (de exemple, Beeson) ™ Caps gaint apa mln are conn este ner se sonar ell ein esti. Compra, nae mbt acti ingroup sina orm nl die ml ~ Compra ferescont tablet forvscet uncle crese dias perfctr in pga ie le de dnd de cabo. ~ naj propre ad uo od volui snd us owl da eat in ahtr rae eterovluile set ave eit sa gets Sind decane dla aa initia ~ Fatract meals fepaat obj rn concentraea pi lau anit dune! sou extractive dat-un rods etal au ala avid ons "euler cua conint medi raph de 20% "trac solids extract wet: propa eta i oncentraea wet soli erative afin dint prodar eget ss ania cae ste ule ‘hein ap ama 56% (decxmpa eet aa eed). ~ Granules pata eld mic ert prin friars une bale soldi icarport mah in str ~ Palbere: prepara armaceuie sald fut fin vat yu aspect one egitim xg ube Sil ppc fen tu de i lai dp igh subst ac substan inert (genera ete sinning fscomprimatl = Prepare armacetice chide = Dect sole ate, out pis Gerbere ne abstr med cameos in ap. “Batre id: preprat hid bina pin concetarea nelson eave dst-un produ eet su snimal fare in genera ml east d= ‘espunde lg satay modiamenoas (de exempt exact id de). ol buvabis care contne medina in soit peli foe eft e abe apt (deexep, Skolt, le Dea 00090 ‘Tethers fol bore coining cont eros + cont de manga + gcont de copra) Ati El este scp) lamba apete NU pot {bdminuetejecailo ara pe ee rl = Infne(alianth inspec In facia nai): sae exact sonst jin dn proare rg meni un sant inp cota ‘pa atemperetud ah, aproupe de bere, Macerafe (iain pei Ip farmacianats):prepartobfint prin sinc in poe 4 el eubtane Yeeae saimai n scopal trp pico ache “Fpotane: om medicaments chi, care cons tm medicament sctv delete operat nap cu ada unl corey de sic sop 2%. Sop: fron iki esc aitor de medieamente ae ean congenic Slate de intern (ural), In cae saben ci ese ere ala nap end a eid ar Est solu ae Se reparh dor in ‘omental cpl tamer prin dzalmseamedleamens rat sb va de pers) In ease de spe (eventual fart ris) pecan instruc wr aepeni in cae medicament xe pet sub fom de pate font enon nan cha (cee talus) a pase depune fal ecient Se eomandt gars Gaon inate ce dist Exist aupent cae se pepct arin momeatlincperl taenta ea ‘espendaesmeleamenas (a ul forma e ple) Into natal ‘ate desp = Tinctar: medicament bat pin dz alco» mbstallor sective dito lta ea un poodu him (Se nem, unt de bdo, ear evar ~ Ue: prepart cae cone sia in fom hi eb pone lui (de exemple de psec ana Dy ul de) 1.32, PENTRU ADMINISTRARE PE CALE RECTALA fos = Chnme ca sla xs cu spent (2 exemps Dara Desa — tabu usd cal), Soponoare, ere medicament incorpont in ut de ace fl ln emperstire corp (2 exempl, Paracetamol septa Indometacn Spesioar). 1.35, PENTRU ADMINISTRARE INJECTABILK (clo parenteral) fone: ~ Soli aponse trie n einai: In one de sabstana et coojauth uncles sdninistest x, allem, alle, alte pe ater a (de exml,istline cu ace pid). De notte, pretest nam Sunt nec vce pl iets gtr, deoarcs seas Sunt astcable Art alte ese erat print-un crcl tl bo Tel (ea dee se rape) tp cop unr fe ete desta un pase de 3 ‘im danetr local unde tebe pict pollen moment per le {ig Facn teanparinantan compartir peo a earl a ‘Sheri ese serps ep en ter ecomparimer near {Greco neeamenn salam spar sal rn psp ‘crn pa done nn gigs nc, = Solujuetouse stereo fle injectable: sunt pee nama Ln erp, enbarbtlBl). 7 Soli tere perfaie nace PVC a In Macane del uot slope atone ipertone (Aen, sll hiperone taba ante int de amine) de electra de con, de aminoacid bamiog umes. ~ Facoane cu plbere dolla care ualiares se ee extenpors ne (i moment wish). Vlabaten slit devine nit din no ‘peut foi econ de pstare der, ind prec n prowpet ~ Pena c sola apone tere, Sent donne ta form eau ca sc lnvirf nde canctssecsr penta nar se stable manerting © ‘ou acest ania pare aad oe eet ijecaen ee pode rin apres unu buon (de exemple prem) 1.34, PENTRU ADMINISTRARE TOPICA (ur extern) IV AFECTIUNE (CUTANATE eat entonle pepe ~ Crema: prepara seal comnta pisme pate 10% bint prin mulslonares usa rs cer ume cv pt elec sn dirie Ingredient, wat in cosmo mec penta une pes ue me cease (de exempl,Clotrinana cre 1) ~ Brule! prepare! hi ince ext spose eesti fi tebe "Gels repr! semicon pe sk de ste clade wnifarm i peat avid oouecare catia Sofie prin presptars pnd deo Folie de col if (Ge exemph, Narfen Ge) ™ Linen prepare bid su semisolid ca ope anpede saa lips eos penta fc a dere sl nee (exemple alec . ™ Past frm de unguet are comin espe spd propor sare (in geen eeu ce pln 25% put ~ Pabere pels prepa ld ia diac sie omogen (de exe ln pide te). * Sarpealc fee medics in pate ne (pele). = Unguents prepa firmace emia in ee seta at xe corporat in-air moe temperais corp (nein Jano. pcerin sau deemed rim Ext ange ioe (ure contin =p) angen: ob (a pimes op) 1.45 PVTRU INHALARE IV SCOP TERAPEUTIC LOCAL SAU st mt flo Bova mana presse (ray, MDE = mtd de ner in sal rn contador bea 2 cere sane Sueno bua secre ae Gedonete dpe, sen. Soli petra sera (ep Palmoryme~ fle cu sae ‘halatorie, dd. ta mucoviscldon ) me "bt en ge = Datel note gn a presente general inher (de exempla, Narcotan*), = lt PEVTRU ADMINISTRARE TOPICA (all IVTRANAZAL se ~ Aerool zai: ena a Bsconne presi xp, Oya ae. re sp, Oly ~ Glas uae: sant sstere cll semicon, dat are al Inca fara peat repent total. = Solu marae deux extern: ef nei zl (pte x pipet (Geena Ring, 1.3.7, PENTRU ADMINISTRARE TOPICA AURIGULARA (el) (nae ~ Soli otc cu decongestonante analgesic, antieptice su antibi- oie: (Seep, alga’: otk contain Ioan Uda) 1.38, PENTRU ADMINISTRARE LOCALA OCULARA sss: ~ Solu oftaimice stele ali petra insta ocr (Se capi Uni’ oinodeflonci. ~ Uguenteoftalmic, care sunt de el i concentra mi mi act ‘tect (de exempl, Zvire guest ofall, confind ecco). 1.39, PENTRU ADMINISTRARE LOCALA INTRAVAGINALA se fo ~ Comprimatevaginal (de xem, Clara = Ovalevaglnal (le xemp, gy, ~ Sou pentr splits vain (2 xempl, Micona Boob) ~ Crema vaginal (2 eer Lome), 1.4, MASURI SLECHIVALENTE FOLOSITE PENTRU ‘MEDICAMENTE “oa 1.1 Ms leben tae in farmacograti Pe bare at mips apne y= eae ag = Tg mers OD ise eae [se ea igs pe [ester 38 i etarpibae lene bss i poe td i i | " ists a a Sea hae) ee) -Ta Tats et mn iaigisuaiaeyoat-1g [ewe kde ta [apa spe Isat Seager Ikgresgmnceioes| gon re gous [mer gst sats nie omy sya fasossth alge eet Pee aiaitema eb eer ‘ia Bi aia ge cf [sree psazal coms on [srr aaa pa a ‘sm ae aaa ee una ease in [sme tne =o 1.5. FARMACOLOGIA ALOPATA § FARMACOLOGIA HOMEOPATA, aumacolgia alopti peach dels principal de bat un medicament fcce tba prodoch espe ogi por an eft inves det Cel pe cae earn bal inpotia cre et recomandat Alot te ea mal spl mands tepals fe obit pert hc Malian presen anise madi eset sarin famace log slopt coped prdase marl (aie vegetal anal a lh pote pode nt nga ‘armacologia homeogti pect des prinpal py amume un e- iment ence uebuse prods apr ngnism sniton aco eet (cele etuete eno impotria cir ste comand Sine scar =celecare sat semaine vind alte cena). omeopals tlizen dept mar pene perro mediate tae x tease din pte orgsnisme animale, prodase miner chine wate a Aa progres ep zeal sa cots Act dite fan ed diate iosetve (ap aol gern, plbere de aoe Als de ese sac nel prodaehamenpte edt inatiameheameatle (de ‘rempl, Oscilcoccinum": pods angrgal prea ib ford de ble ‘are as ede et ease bel). Ta er lc vor ld ‘bare pune meliamenthemeople 1.6, PRESCRIPTIA MEDICALA (in atentiaasitentlr de farmacie) \ _Prescripi dil (rta poate canine peprte medial indai- le foul finale repartea cror compost ee sana narra ope) sas frmale agate, caoeepate de mode pin sais mn ator |. substan to form amacope comin, ‘Presripin medal su Somat de ref ete camer pe baa crue ‘aemacineiereari medicament, Ea cade aligns motel im oven ‘superscripts format dn: ~ seta rete unde gues insta mele (aint medic n- vids polls, ceatral de disoonieptaaent, pal) de ude te ~ re revit fn frmlara dee nde ae ompletents anele ‘penamele pues, ss ~ ange spc pei unde ese oat niall boa sna in tpl de connie mums fd obser in wade digo: 4. ume pecin propia le pat lt 1 unr pearson = prime 6 aes pesca in rt ao ral eft ee, “Time: melenestl preps eae: 1 Mepis etedetna poco in rma tb se pit metcnestl pets pace admins exempt Ms = Tie ttn ntl vac en si, Aca nd ‘ies necern coal onl ogi ated clr soe Stecancstor cre ele pepe, vate, Sete, cea 0 mace errs pte aot amine pce, cl podtor ‘sl (ormle fen) abi na est nce tcf cpnde nda ie esas cr ‘wi ft endear Pes acuta perl nile DS (ela tre sper, nn aid ~ snes) Ba tebe ede te pound ace pesmi dent clea ue Inc bk Tire pone ume ntocms 2 een dat preseriert ete ‘Lint semare peated ps tampa aii store desndes orem "NU pea one ecard tence ees nate aiork amine palais, repre csi mineral eine {gue aims sient alpen mje e- ‘Shimer amicus sate pee pot etre ace m0 ‘Otc ell In mod ibs presnaes eel prs mei aun exemple for magia net in ora oss Visuals \ on aa ice svt Gauri) 1V Sle 25 mg (1 100) Mice ft re i nla ca he 1412 gs ter oe a 117. NOMENCLATURA MEDICAMENTELOR (rice medicament et prerenat pe pai sub desire uk comercnl snucit pe stbolue™ epee mar) "(rade mar) care sn ec Pec ete mii reap rh de cet denice esas epee prospect plane de ecland artnet Dedesbtensaliiteulesapert §idenamiea comand internal (DCI care, cep sear medicament Ingo categorie ine delat pert derenem ramroaedesinoine sb care eal spre exempl: Pace” (atin). Cosiares med amentlor afc, de le, dp DCL. Din eet te eat ch a ep Siac prorat este cunostres medicament pins noninaat tb cae spe pe ais cpr crt a oe pe pm ioc DCT al ‘urn parame, debi comercial cu sibel de exempl, Lineal (Organi), Se pone observa, ck demi comer sn ester foarte sopsive peat compo aun sau modu de sinister ‘melicament Esemple:Aminoven sai desmnoac pers amiisrare ‘he Asmofugs sole olf ansinaich; Ant compeime de cabo fm de alice fee de neuralare a cts cell gstie;Conrae seid valpo ndeat in epllepie (Qrevine cre de conv epg) Intra exudes pert adminicrare i Resa: comprinte pe bind de naproen, date abl veumatnale; Heino eampeimate ‘uhdminiee (emi): tag sole mace nota medi anges ‘ib Tse? sp atu: Tusincomprimaeantanive; Vermigl: pension vermis (hein) ee 1.8, GRUPE IMPORTANTE DE SUBSTANTE INTALNITE IN FARMACOTERAPIE $1 IN TOXICOLOGIE 184 atcaLorzit Alessi sunt state nganice de gine vga 9 struct com ple react bac contin in leu aml dea foarte ee ‘Bacodinami Indo mi arn done mar toe, Eth ae prod ‘nee. Emumerim ali cel a dent. Ateopna slid lt din mirigank (Aap lado) ae pln- te slince, ate acne anclinege pusinpatilie), lca ma Colaura nee act ge ii onoarinar vind pei eet ‘mri Indore mar ete excita l SNC. ~ Chinidina sled din scour ror chink (Cnchona oii exe un ome el chine fost in earlgie ca antne ee antennae ieesaetnmeemnteerice tas oes pee Soe eee eter err ern tociecnaecamiacnanetrar reese eet rear acaic nara oa ed eau cane armicenetor ramen Pepe gher ae are Spaced econ rage Bioee Ceeicmoteearteen Samet siccienansprats ee i acetilcoline! la pla Srinath acer iat =e Seta oer ee abana onan opeieceree rent je tent enchant reer reer ee Cea emai ee ee seaerer rae ttn eee epee racers sees ras renee Teena ‘paternic Folost ca dro de cite toxicomsni: produce dependent (morltio- co aoe seer gua oar ear aire mong ornate esata ate mee meee meetin Paster Tae mecgiaeatee ames me fi ~ Nicotine pricy eal di ttn (atau tabu). Crees dependent ema mar devine oie, vind eee praise espea temo neuronal dn sited nero een (fete pnglplepic). Papaveria, alld din opis dar pepart site ae scant a0- past find remot al muscu need gasoline lt a Sind de olonltai oll! intestinal bare, lor are ~ Pilocarpng, alld din arb Papas brand ete sober celine (psinpatconimet) inden afaloge ca ttn = ‘lampsacom pene eae mis (jones pup Pe cale peal ‘Se wa caida toxic co stop ~ Scoplamina (hon), slid midi in wel lane solnace, cleanliness (prasinptaiie) anime apa SNC ‘cones ca depinant moar sett Se se, prepart mln a ‘msfcamentl Soba zat a ata lear ier sire. ~ Stcnin, av veel, dol din Syeor max voile tn ect pene stuns et otiant tant In dove mic NU se ose in pret in erpestic, -Tubocurarny, alld vet arte ok proves plants Chon- aden tomertci, ee ean paraznt a mca site en ‘loare setlsine (ate ste neurtranentorala plac tre eal seurmascl), Detail sunt nent x aja in area peer, ensue une reel mca complte (na! dct below onectt n sapot vse ar, ae ar mrp pia pra ‘irri, 1.82. 61100z121 {icc snt subsartede crigine oil cae cds prin it ‘in out componest:o component loft nuns mal me monn pute dm gS ae a ‘macolnani, cu un poten eat Cela pic rep rope lei ga un sant oa din depo (Distal purpura Preznt find ct mira aia. a stacserapla oder flne digo- inl extras la dee nes (Digan) care, ato popisior ‘ale tniedace one nde in ines cardc tn nee aa a ‘uli (> Caps MEDICATIA APARATULUT CARDIOVASCULAR 1.83 FLAvoNoIDe LAvINE) Fino repre opr de abn cede ppmen g- Sent penn epson sce rele hacia ce oa {3 invnd in compo sor models rane Dineen rp Fare bof (tami) evince io nine ne 1.4 PRCTINELE etm rene mi i lt re ee ra nan dnl pssst in ind ent ‘eS pote repre all elon ce). Avg pope ‘Sine prn e mano in tenpetic oii ine. 1.4.5, SAPONINELE ‘Siponinlsentsubsanc e xg volt careasinleszalorocom- poof cen overdo) ons meg hon cu tocar Fel Pipi compu ster din membrane a opti tion ‘edt find osama peste cd val in slo oath el corps Frade fe oer dinitrate, EiGjone tot 9 expstorasa pe ale nj decane berlin torte Se aloes pone slr unde sspens eos resus es deergep, FARMACOCINETICA GENERALA 2.1. CAILE DE ADMINISTRARE $1 ABSORBTIA. MEDICAMENTELOR 2.41 Adminstraea pe cle oa “disatraen pcs orl (er 0 = po) execs ma ferent -Absrbfa medamantlr ae Joe elites sje special in ‘one superior unl Ea ee fret de diva sa upendares {evicantls a ap Absorb poste imino de reser lente ‘ashor medion acompatie ye spar are, Sod geste pin ‘seh nestalasant unl medesmente:ecaltlpeiclin (pea line} lreting, nina. Die set mot se comand admire anor t u Concer init peach ‘eta See neleamente ptomacl plc spina or nan eso (esi ‘Vamplcinh, Damp, soba tate penta mace pais (ed cats pede, defo oate elt entinaatoare wet Alene» AINS) [> Aatnfamatonremestecoiene fn cep. 19} amines ‘media Guph me pe stomsel pln, Une medicament ane nt rene {he sub form de ape etre (gasrorestat) ae eer - ‘ete atv nana oi, rnd arte smc (Ge xp Bicol). ‘Tarts cape patrons sunt rate medicament cae el c= eer eunuch! ital (Se exe, Budesoal). ‘ale ol denies contandet incr de visser gtlger operas stare decom 2.2, Adinisteaes bing ‘Adminate sublingual (6) ze avant ck sg nts et nea cule oclind primal pss (Wee) ri fet. Se lot ents Dine meat cae st acponee pee sec Dinan pte [popu de colicin ils patu acne eornarodtaoas [> ‘cottoare coronene nap. 9) 2113, Admintrare rectal “Admins etal (po eto =p) tien tt excuse = cae (modesto et pnts uelemedcamentcare treble [3 cfnees in dsianteupntonreantermiecuamlnoeeren (praca ‘nal nce AINS ndometacn, dfs) NU e laces etalk {ncaa dierent anorectal exeptnd mdlemenele end ‘Sie deadninerae losin retool ulcer emorag. 2.14, Adminstrares prin injec stbewtanate ‘Adnstece pin bj subeteate (ee) ete ost pence media mene hideslebe nant lector pre cera iz ih clei Jel im mii, deoree gi engin et rata pack neti ‘eat coset In blew sodroamde emorage, douse dc a Formaves de hemaoume locale 2.4.5 Adninsenea rin jc intramnscuare ‘Adinstaen pin cl treme (mete even ull, Pe cao ales nod in onan sla dros, medicanenle pose supe Alef, dma Lm incoet ed expec ten condor de spied apart de aces fgoane sx necrie tefl mused! Cle im ete comraidat In bole inde Iba deonce dtr formaes de heatpue inact 2.16, Administrares pein inject intravenose () sea pein peta endorenoae(PEV) "Adminsrare pin nj nirrenas (xe) su pin perf endovenoase (©) te nat nat pena abo in slo spon. Pesce cles lnrode in orpnismmedeamente cares itn per rt cle nee sreincanue de gn sole hpertone up are preib) sule "ule prodsle de sage plaonl Arete sun acfune imei con ‘all dvdr node posible wet edn in period presi Tide ti i PEV), co agurees un cnt constants pe units de tp. Uszares sparta competent de saiie ional jennie (ip Infsomt injectnat sir sete pei tee mare sin- pe Mediementde cr goin amiaaina, stein) seadmistead Se dlomtein sla none tn PE, an tm foe estes mostaraea (Geminie connate bln ster tera induces 2 spenlc« solilrwkoase (pt proce embobe grisaat), cepbe fin levees espa dense PEV (ntalipis potund") (> Sous rus penta noe parecer endonenoss inca.) 2417, Adastearea pl aha ‘Astras rn nl een ane eer (aca ‘ne pcasesalinacrosl) [> Aneel eneraltnesp 2) 9ntratamen- tulusor fit plo Ip stl boa sundae bronhodatatare ‘benadrenergce (albu, fot) gucocorot ilar (becomet- 1220 dprepianal (Cap. 26 MEDIGATIA APARATULUT RESPIRATOR, 2.18, Adnminstrare prin abr catanatt ‘Adminsraree pi bore cna ptr edcameat ew stele ce fnlosta pune tant: wnguent fpr cu ogc ashi ain, 2.19, Adminhtrarea ope (pentru actiun loa) ‘Administares topic (petrentionlocl) pepe ctl petr t= meron pr de urpuete, sltiuspenay payin nsec Into dermatalopes Exit nt gunguens apolar car rms le a san (e exempl, Nurofen” gel ~ care conn baprfen ~ 9 Fast” fe cae conn etnprofn = Imparvadurerdormuralare na acu) 2.1.10, Adansrarea ope intraazal ‘Adnistraren topic inranaral se fected prin ita ese pre rte oe avind elt anime, ecogestonant sun anal. Ee Inde In teen cburuce nek important Pentru medleaesteni, nsconn naa ete wt sen canal aoetie (bomen nite ‘eccipoiar, ADH), pi sles or par. 21.11 Adnsrarea ope cat ‘Adnan topic bel else i dele forme de seats pene medicamene cu efet loa pin stu (te peferaie e ‘She bdjonnren cor! bcos ar putea aes eet tant) lain ‘ome low cu Cea aan In mat oase lero nero "ein neh ping perder 2.1.12 Adminstrare tpl caart |dminierae tpt oar login ofalnoloie sab om col ol pet desist sete ci de sini) 2.1.13. Adore ntaeca() =adminstrarnintrareiian () ess eaeeve reeret doar tora edie, deparece ile ta inte mide! pind arden nerve sialon inode (deeb sine (ede esate ave. Afefe, en ers al me ‘ca st aborere cals ntraraiins! Pt node gum apestece ‘pec dente rablnestere(Bupracaina", Maree Spal drcortzon ‘eta bidrocorizon hemsuciat canis aabinanié aval aua in St ‘pect da suman SE 22. DISTRIBUTIA $1 CINETICA -MEDICAMENTELOR IN ORGANISM Distesates medeamena fn oransm prcrge pat tape: teamportalin singe ane ents 2 tae prope = Saaeninfete \ (tt ce sant seit in organism, madicamentele sung in celia sangvint, unde o parte cir lege depron plate In eel ada ‘stil or us peta important re bldsponiblistes crepe "proce dn atten drut care slung ln sage Formula de ‘ala pers n medinment ee concn emt dp adminis oi edayenls® ~~ cesta ep edminor alin cel demas a ep ee vexce {hax i vlan uct de de ps cseet oma Uo at parsmatrfarte nfarmacoeinetl ee peak ( if ‘in dis enle,rominit in onl nee ob frm penser tinge concen part der sled «coca mame) Ene ‘ident tings pen lay foarte rap n adnate cv ‘ein admins tm. gsc ma len nadine al fmt Jeti adminsuares pressor cu cere naa rela in sing, medicamentle patra spl In mod sent In eine np int Un se depoiee loft (epee In feet flys) tea dete orane (et, ne), rg owl eh Be ‘ogc (LCR, lial srs, a anume sobs prac pot troes bse hematoencelali,pitund in astemnlnevorceal Anes futur mediaestlarse desert dps lpres de amcor spe fic eantaren menbranlr else [> Cop FARMACOLOGIE MOLE- CCULARA SFARMACODINAMIE) 2.3. MBTABOLIZAREA $1 EPURAREA ‘MEDICAMENTELOR facearea stil woul medicament fn eg produce prin dot ‘Prin metablizare, proces pin came eden te m0 sien tnactvas Roll pnp revioe act atu, deviate ‘sor loam” (in sao epic dn hepateeaeate severe s fin rece sees mecnis a fence), Un agent medinmetog Seton sepa ensielor dn organ ladles ibn Stn indacoare (cu fet ue asp ensele) sunt - peste alle foots fenton, carbamazepine nese tole oor ‘medicament micyrtnds eats, A tne oo eft de nar a indir all metaolaaermedieementlr ee nr yin, ‘sted cal escuela ect, ‘Un rol debit de important In metabolaes medicament evi e tocromalal PaSD, tt ca smboll CYP. Acta repre spere de eum care sctonn prin ranter de econ neal ‘etl substan Beco rnt ain de un compos organ sora cate MAREN, VLADIMIE:ANTA MIMAILISCU trae cite eal cate tn lures coromall P40. Ensim ‘ot notte ect pre cu (repreentind perf) nae se ada (hun punde del terran aii apt ole museca nse a salon urmait deen minarindicind gona speek. Aliment sat Iredale cre fr nto aupn ener dn cern 450 {erie din sera cant cu al redcament care sant metabolite prin eornele YP Eeempe peu de grep inhind C¥PS A¢ cree dpondiate dip ot (mediement annem acjonind ca leant sletv al canallor ale ose (mediunentaneroia lzat n tamentl neti ex HI) it eile CYP din et cee concer seh pepo an ‘hrc anemia (anita stenue de gener «nae tenzoiscpne cpl! (medicament rokinete neat nef ga tocol le emideprene, carvan, tecoomal taconaa anbele sot ings) and feist saps enameor CYP hepa, mes ences sec a aera snp ui de spare» uncr ‘uur eardorarcdare “Tell 21. Medleamene cre cons sata penta enzo din sperumlla CYP (ms [iment ex earner ine [CrPIAT [Aetna pret ead aren Op soins Gan eve ona eum let icant acceso) mariah dicen asp) [crc [Be ne a eta ops pam (etc ln ‘kone te) be len pyr sid bend art 2) . [GvPUCIa— [Diner (race george | tee pnt et snr cansstraps prossno ian tama pa cics Premera. propenoll ean adrenepe § ces nn TA gine [EHPaDS |e oe oar nc) Ron Toe ‘nectar [Sa [mn ger cn a aa Gr etirdseee ee es sone sen degen Ae exemple pv guna vat de medicament aupa cro acvone ‘enue din ermal 450 Tala 2, ‘Prin excel renal, vb nance edenance-al ace soatn- fe Glearanceal plasma e defn c fndvoluml de plasm eprat ‘scx subs aunts dein (+ un mln ge cael dup oma Vier deduces edema FEV Ceca a na Canam = ‘praca complet «wal medicament dn orpanem mac exci r- sal eet stata heptel de metabolism + eae "ea prin rane (isin). 24, TIMPUL DEINJUMATATIE, ‘pele cnt ost eee 1 Contain: iat te iat oxieut a (CUNMARCEN, VADINIRAANTA MIILESCU ~ sinpal de nue leat de faa de dtp (4 car expen rc ecest peta ca subst tanga jae concent pa mati ator ear nest. Ee un ip malapid ~ unl de jamaica fe de pure, 9) cae exeit da sat neces per ca medicarenl lang sunita concentra pla ‘sce rr eiminr pe ert linia ind ele renal). tun tp eu valareral lent Second chpuce une ube ate eta peste 98% esi oproape compe) upto prion ep oral are det {pal etnjnae. Formal cael mall de jute tn general eal de tee ‘Gave pamaie * 25. DOZAREA MEDICAMENTELOR Prin don leg cate de substan care provoac un anu fet farmacalop a tol se evident tables dander consi una dine problems fundanente al fmcoteraiel oseslapel tract erie de fence In minus edu faa rape ar supradaiiept ves conerite ‘em de pve pn ntxes ele Downes uti medicament wares taport ca vinta ett corporal (exact, ex pra orp), alen faint ta, ste funcfonls sich graviates alan trate so de eveaiin carseat aces, puns peacoat ‘tevenule el adverse apirte carl amen Lunde mein tment admins, cum rf metosens, medina seep, pn, se onerous lvl sere (concentra pera ese) penn exit cettainen ‘eet doit once ‘Sables dozer in cus ual atament repre stb ¢remponae- tinea medi cura Ta ore azure, pate sgt, dose psec se vet dup prospect tablet pin unl farmed lela giana «1 dors medicaments tebule pect urmitoardenofsni: ~ ete recomandab deva mini erpeti sic dove cen ml mich prin ears efatal bent Ia ae flo eps ui oped (pre deoseie de dena mast erapeatc, eae fd aro econ toxic expan a sest se: ~ dozl po formate petra 24 dor (dns ni) ndcinde-semo- sa dept (nclonae) pe ze Be ot 6 nla pnts 0 rd admis (Joa ou) ends se dec sv repre “ ue, Mur dona foment in alate pet tenga cs pole Input pe ae ape rie, rita de adminsre dies ort ean meant a chip cel medieunen carl ani cre erapetce Hee tt de neon de meer a unl nivel sere eet Ulett, nei severe admins a intervie de cite tel, ca ma go, I ct se sau chiar opt ore. Fests mediate adnate old pe (Gov, nite de peer a), ale har Inner de ‘pts (oldani: ~ lnurele medicament cre etrtamentincspe cao do sa mare ‘sigur concentra seats piel eee avorae fa scar ip. ‘Acta est dora de tac sa dora de lar fl perte dian vores onao isons dex ~ nace meicmens,c contin Is amine urmitoare se tlle urtont cu odor al mic dar ae sigue ieee neces ‘te dona de intretineres ~ penta erie substan care prune in xpi, eo canta mic ‘ima cie proves eft tice seme fas # oral -dova teh “Anu cn inp in pel cle via In cet en i mein eines a format ote de date beaut (Di,) ere cde You imal de experi atte cu es (100%) dona ltl dle Ds) ‘ar cide unitate din animal deepen oe (09) 3. GHID DE ADMINISTRARE A MEDICAMENTELOR (in atentia asistentilor medicali) Denny suexpLicaytt “Ansar nls io odcee itavenone In np scart uel secede, “nde eraara bac anamea vnc (hice ater pe material tin de comport normal ng vehicle de ental ttc: ches stops rapment dest adpes, gent deta medal, fragment de pce, agent de rumors lave de pars bul eat, bl deine, “Emploi = pep frmacese sli pti ade care ade I te gman Inmon eempertra corp, permind shee subtaet Ace pin ple plas), 3.1. REGULI GENERALE : ~ Iain feos medicament sevr ci cx see stich. fermenal ecapzare respect nsptor (rfid fare NU ebute ares). "Nico medicament NU aaa dat terol de expe srs peambal sua pe het acon, te dept ~Mediamentle vor fue in abl egal. NU ee permis wl. ‘tea ur abana seri pede inte meinen orf psate conf instructor dep a ‘jen din propel insofar Deck ma aunt specie anu cod eacite depute, medcmense vor inte ancien cu temper ‘nee de 16.200, ceare de rl de lar alipost de ale slate denmeneal. 4 Anume medcamene sects prvi ie bs temperature de + 48°C i NUin congo): ili imunogiobllo acu serre Hpermune, produce henge, Aca hat se melons de he pe smal aun prospec apr In Giger cu mediante NU se Sopot tet mere se ere sbsene chic dena ace igi find on ff Prous soe din gier eed nites adit inet [ntemperaura corp ste x deste ners mia vei lament temperur set de caret sce Inject tun pote ‘rodoceneroch inodus x patededanao rise vento! ~ Fant hea produse (sunt pine!) ae ble oct in oagetor mame cl are ce Conse au ab orm ghee pops ‘angels (PC) clprecptt de bling stnemotled A Deeg lr Sefice rp. imei nits aint ii ene a peat ‘corp Oda decongat,un asemenea pode NU mos poste ecg, (ete ear de eatin aru, acute cs) namie cpt seni anal pec. steiner injec let “Seva respect csc acon detlr (exit mameroas mid- camente—in special anos ~ case pat npr ue doe 25 oh ecu goede de administra actor. ~ Init administra su fect tataments,pecrans cae ane east sri sew ap eran. Pate ase eva core de dk su confundste medcaentor dn parteablaavlt se recomend st medi pe cle ors ends ‘ec assents medic 3.2. ADMINISTRAREA MEDICAMENTELOR DEUZSISTEMIC Insccasth eerie ine maticamente cae stones isl spre mor organ ste apart a nip negli, neat de. {al peunde sant inde. 4124 CALEA ORALA ~ Aczat cae upoat ti eblnvi cmd ca con xe bit de det, VS nero gt se cae ff a mod a emer ~ Medians sisirea cage soc lng i= peste spn). Cc ce ut deep et nao fea! peator cs pp ° ~ tchidel cups dearest po ames cu ete can dep, | ‘Tbe 3:1. Cie de administra a medicamentlor ces inp lope doe prospec isto u coon asemees anes Se pm an ter In nin ot NU seer nodae medeament hide Int-9 pore de [eae [Sate eae (rine, decree red pat ch te incite! estan [omg ues Cate mednl tu conaat rss prepare penta aer- etry emma sa deradarea substan ei Renae Suspense dimen epus Din acest rt Saon oo leona van A). onl (antvete) eect (cae are aise atta), Tote angen ue tices ch unin funda dese cojancvae ape marines plcaplon utr ‘or tampoane confine pele din compres tie ax ane bgt ‘nl dest ela oerremfstedn chip deepipce 34, ADMINISTRAREA TRATAMENTULULIN UNITATILE SPITALICESTI In pj dete de adn «medicaments, pot exists wale onc des un pala al sa hie inte sce so itl dar rar pal deca imine ars mele se adits in conosco ‘Prescrpidnpgin deste fl de oberg Tceath pind, medicament sunt numer f melons cu demu sate comercial ub are se vex Infirm psa). NU st wee LCi (dec poate alter npn) in sesprin prin ve seta {fin comnt Alu de medicament un sinatra de recente, fain deans ¢daz penta 24 deo urate de menoaren del nr rere. mal evento peice ont emp Bahra pram rt gmmocc) ef detane, ‘Sneed pate sa {ign ce ins nme, 2 Rate nt 0 dura Sed 1a utc cong 0 tev conpin ep, ‘Cision ey cee ep Sapo 1 Cavite x puter es rc dn ‘inte te ok ra cee oc oleic ee |. redo nt Supe den ppt Dan itr sided pra 5 ll been de ‘Neate de ep dant S454 ‘ned te epee pri "Pri de ese dS 4 oh red 8s [Eu Domr el corte rash 0a pasa dec mln ‘gerne pa. 5 Reenin compre ge came po igs fitleens adele ‘Smo ct an 250. asa SR oli peer Lite son: 1 es (mp nce pe Spe ere ue st nee, fk avi meet curt saa medi de gd intern medleamenta presen fico un atl avind arn ern toae san snd oor de penta armani ie 4, FARMACOLOGIE MOLECULARA $1 FARMACODINAMIE DeFINp stexeLicaTHE Corp sa = gop de mace newo oma in earn tua bak misfertiorcererale (el despa in tng) edd pect slat pe ‘ecjme dao aleane deme cu subst cen: hao fol ‘sparta in rere mot extepramiale (iti utente) “potamas= lc regan dn net itn parte entero ven- twill ste alta al ml uc! nero oral dn oad ca Fancy imporsante: ast eee comple compare tenant ‘eoonena tresses snail pend seca! de amas ih (ental sti) contoleut dures (pa boron anh tact ‘eon poz posers) umerease Res vee metabo neg chiral hidrsecote, respi cul inervine a ne ‘vuln prodiceren sr para erst exo fa), Tocusnige bel neg’) = grape de nero inkl x pigment siuati ls bats pedncullr cecal, Are rl in motlies egies (ig ctr Test de pers (ai alps) > Cap 28 ~ MEDICATIA ANTIALERG: Shap = leita te neuron Bato leg decomigtat (single ‘ona ealztspis intermedi! neurtaneitosor (= mee ch i, los = mash de stant ena stot aaa endear cereale (os in deni una i saga), format din mal mle rp de earn ee ‘i Ai fa snap neuron di speaep ote cle septs. 4.1, FARMACORECEPTORIL ‘Un mare muri de medicament scones in egeiem rin interedl ‘or enum eeperi armacoreepor supa ctors pote fet agp (esimlaea aces sa antago (inhib ci). 6 CA MANCHA, VLADINUR UAT MINAS Receptor st mcrmolcle petee carp ep in od pif an nite ubtane fermi comple sve loge Autucol honben ms (peruse medicament exerts retenes pis nerd ceo espa ‘Se mums farmacoreceporl octet cape peimete oh ateac- towne cameicmetle Manion ore ge ep TS eceporkadeeeric sunt nivl terminal serose sn te panda mules cu ordain Se dees deus cer " ecttr , psgenglonr au postop cae vf a muh ‘tea slr angie; smal lor produce aceon 1 acttr a prsnail cror smaire deter seen Sc (idenondelints = Yecepor radeenergc sunt stro molec situ terminrea Sno inpstic spn le mes ~ rt ae substan = ope ‘link Se desrbexe dot eter *rectptr loca opin ia moc simular lor are eft ‘E coogeeecablih ioc tte pox) atonal ‘crc (ono po) de acceler ral ere (cone trop post) In pls au eit nhtvoraapra most intestine prota = esplor issih etl a bonlorsoulare lr pro- ‘tee bono bronhiodistaf. np relat vase pris simleat gdlina mol = receptor colinepe cut localial pe membracelenewolor pare sip dn iri npn ispand ators cu acecld. Seip In douk caer: receptor maccarini (ot x M0) or sia determin bre ‘Sead mare areas es seen tensa arterial, cones ‘masealr neste consi (pas) bro cere sere {ior ia abarle bron, . * recep icotnl (no cuN) cro stlareprodge iar Iipertenane ae, pllpoe, lie ceetrenprstinu Ines. cl i cpa mac sit send pod ewe ald oe din eset pte ana mast) ‘mle sin ot nna cl rote dei leo ‘Seat sto a eeplor cotzoi fin tops clr lag acocorict si ior snes de proineesiatice de protic eee satin Instr rind wn alin fee terpeuicaecortcoseoar: receptor dial sn stun ocd: medicament dale i xr acfonea pin aren dant recep vied ele pout dn pet de vdere tno, nt pbatmato fect nee dn punt de vedere ‘nat ft dromotep: ~ receptor dopaminergic un ree tn soap ners de i ell vbr ena di inten round la stnlaen ca dopa (ad {inet rma di DOPA = adrenalin) prin excrete tort se produce vasodistaje n inchcucetres deta rina ltren ‘aso coronarine rere dbtall oe decontacpe animes sun proline, Prope ces eee: sun wit incomes {octl nape el cardoges ~ recepior pectic pete eltopoetin (coral de cee ito ‘estat in dye hemstpaic, condiponeak actives see pen prolifera 9 leer lormeor nee erobltce ia eto (ems) mare, ~ receptor histamine st atc apne Neti Se deetbse out catego ~ rcpt cor smal delays tre apr, r= ‘ge esa ater contaia yr nee tena pos rom Crnbloconstii). Acs enomenes ints ot © ‘av nent focal anal sunt inate arbor bone a ‘i cine de asin bron: Modi alr ebaness pe lcs ascestr repr recptrt My stan In cod gaily cio excite prac © hiperecreitdt n store, Media antici modern se bsee pe substan cae loceer receptor din coasts ~ receptor ivllnl lp pera clr vores pun era nine nel ande cet ve aetion pin meboliaea cdl Jn belt tp 2 oaanheodepende lo pot acta darren abo sib fst expat igual slim ‘ie ipo sunt lose ataentl sees ip de ibe sara, scree rela erporor nin capacitor foto; ~ receptor de eaotiene rant sta none intervie. seed stn bron roductnd cota msc needa anor bo his cresnd pemebats cpr eo tranandhesde chide mobic lescocte cae nies cal mscoara Tatami tae bre nt ‘ill dele medicament antag seetrler penta ee tees “ receptol speci pentru occ, a i mimes (mjc we tn condone sctvintn cone! pete dela contro aero; ~ receptor opal (movin) sunt pean! im neon in annie mata le SNC (alam steal be stella) iid lect sorting deren produ endogen’ cues prope endoringeeine) ‘CRIN Wa ncoaN, ABI MANTA MALES ~ recor petra prosaglandinesnt ml male lr Penta poe tapaninee est receptor ola cu PD. Petu prostaglandin exis ‘eeprom se i cosa gastroduodens 1 Fenra potglndaee Faun rector not PR tia masse rors in motcltre ern femervie Pet prostacicind exp ‘on nota stan macs asc. 42, AUTACOIZIE Dine substan pode in mod Slo de etre utr un ol fan nal civ eine astaceso, ce conet ot rin intermodal receptor. ‘Aisa = conser harmon! lol, dar care NU sunt seri lanl ndoriog cided ese sont reprezena eis urnatoure obsta 1 HISTAMINA, amin bogens et ere de granule bazfe din ge de mcs pet, masons src ude cll evens Ex ac- ‘ness pin ermal unr rcpt sellin elect lp: “Teton spe eeptsiortip H,hitamina eco eile de ‘perenaiiate med (wae alice de ip = ree anaflactie). ae pot forte tense ance: keen are ena (nk a tara de yo eral ‘ace prin vada rtenlelr enone avenue pases ple: 5 pais de ural deme peririe eu sobre (deme Snponeraic) eer ign, in rere pesoeaiicap- Tae ins de tranedare de ei plasmas a ppl etre: ise pce proek(conrbi aca de sim boo) ‘rn bronhocenstiea prods de conetura masa ate 3 Trochllor mi ; = sjiocind saps ceptors pH, din coat serpoc ist ‘rin decane osc gue pats in ad otc! pops 2 Gece hrs ido oie fro lap era ate fond aupe rector ip expo pesagp itn ‘era fection a ell noe termina sting din ‘tema ero ena. local or cesta eepol un fle asap tapes tn str legen lune gate noi degescte Cu un ermen gee ‘ie eeoene Morale tint deena c antihistamine. xi dos catego ‘side snthitemince: ~anthistamince dew semi, cae scones pin boss recep torr 1 vind cet ater Dine aces fe parte da eae Yin cleakina (egy, cloenoxami,dorfeiremina, drops mina (Nin), prometcna(Romergn). I genera I nd: loratdina (Ccie’)cetihise Cy", lemeetana Xp") (> ‘Anthsmince de sitemic In cxp. 23}. rmacoterapce suns utara eee; rine lbs des edema engine ‘otc Gulch; beak srl enomenele alge rose dfn eins a de contact cu nele ple, ~enthisaminieleataclde scones pin ocr expo in ‘uence and elect anaes ein edi (Hate), ‘unidine Gane, matin (Quanta), skating Ci) (> Antistaiice cap. 6 nde accep le acest ‘ler pec seu duodenal: enfin de et pve emailer “este supine n ele terval heuer apt ‘ere edeaeatons produce de meas INS. ‘ BRADIKININA afc ke Kinng, forme sub cine ei en- ime, alien a plan n une stu Ete an andlor tern ‘re permease eapler, produce cotactis macula ated, boa bosons stmaleas receptor der. Aenea ea ca mediator s0- nb erie de perenne contra mec de dedngare are de stm rong, ‘ SEROTONINA (S-Aidrnisiptamion = 5-417) ete o end togens event jet animale vegetal, precuniaunele ein Areata Ae neureransmiitor a olla poducees oma» who proce cogine {let In proces de wrsoelar, ne fini nator seine ‘n fuel hormonale legals, podace conta sl muse tar nee, vatoconsc(trandnd HTA),iibaren sori xc. ‘Acjoneat pin intermedi uno ceptor pci (iu. Asap bul ius ae lect de stmsae perils itt acl obdonale ‘clare; supa opuatullcdowscalr ae x fect ble ips ‘mere apratlrspzatr determin bronhoconaie ype In ava rolin mecnismal och al ste depreae nhbon espit ‘eseotoni fd flan eat afcgan [9 Medeaentatdeeesie in ‘ip. 22). Malaerolis produces viru de cast eta mice. Cul caret stopad aces fect fd ondansetron (cre locos receptor tertonnerge, 2 SISTEMULRENINA-ANGIOTENSINA,Anpotesiogenl esto g- opraeak frat tn eat eet natn asa Sb fans reel (cori secret de paral tsps inch, agitnssogeal ° se tanformat In anptesn ae eee nc. In um ri en Sie deci s pn (EA) (ACE = Agen Comer agit res ants I eae ae pee Conuiarg esineaes cal deadoeon, Tur 10 te vee scene deo in ura crs pode t= sien pects cc de medicament ae irvine ape ‘Seacall deseci ae “Rites est unl in ficor important de produc shpat eid, sien nd comb prin matcamete crnhbbensnn fr comerie menjont [> Medeapispshpenea aod esi dh ceaverc engin op 3 “F ENDOTELINA eco peptihprodust de enol vase. Ar fee ysoconstipe persian acta im contactara ‘mudora auprauracoma ‘sete de utc pari clase pier, ind pow nose membrana Alle lca: " lotanoldea btn dette din ald arahonc dn ee pa te: prosagninele protacina, ombonanl A2ilucoinee: "actor stator plachete Angloesinogen (0 lcprti format in ce) iene comes Angetensnh Fanon ane Con \ serine 1p Tap de mc pincae sfomack natal Ga gone (arated etorcoy etre dlertetpe se ecules m { PROSTAGLANDINELE fe pre dine scosanide, se ares sb snes uni eime(icoesgraz) sunt structrh cel grit lo acta ag, pene! pin nowt tpt noe cee de Ale Diferteleprostalandin ua ere: male contac manus inte inca well sc presen sang, secrel ai A somactll temperatura corpora agreaze omboctle, controled permesbisea capa lprocade inant. Unde dite ee su ar hate in metrapiepontprtm [> Age cc seni tcl ta ‘ap 12] ge nou-aseu cu anus malfrmafi congenital cai ever, ‘nde cal arterial uebule menfinu dessert pet aig proves copa '# PROSTACICLINA (an a scoenold) ate tot st Upc mend tt sob atone cloasgenze x relent mural need ‘wong muscles tern, fib sce gute de aid eh je sete macs protector in stra, ib agrpce place trombecien ' TROMBOXANUL A, tot nenod det din ail aidan ee sinetzat in ttmbocie in paliaclere El favrzsn pears tombocie Jeena eer ene vaca, peca #vsacont ok in conracia melt rete dn ae, ' SEUCOTRIENELE, det sle sore acl gra nesta, roduc conic msc eed npc a ahr mi cae permesbl- ‘eu cops, fered eenadares decide mules mice lac ‘elor In once de numa. Au un limpet in resi de ere iste imeia spec neil de son brome Antgon receptor etre leucine st lo in tatamentl all [> Medes atin items in op, ' PACTONUL ACTIVATOR PLACHETAR (PAF = plat acting foc) are srt Ipc ete prod de ecole polioconacet, Iracsiele barf, mac wombocte ce endotlale aaa nde Cel rele. Ar seine vasedttoar cet permeates adr, pro. {ace contrac pte al rnb (prtcptd, dc means cz! desi rong) intestinal! gtr induce gegarea placard (to ects, fivorisind atl trombone ater) eu beara de womb. adiamene cre oh efecee neces PAF rt cromogltal dso i tizt n profane de stm rege, glurocrcot nbalster vind cea indies. a “eal 1 Uncle sctanisleeosanldelor (dct ale all aan) feo —fesi_fooma fo TGF. [eeu es eal fos | fe ae eee = ele Sa eee ee (con (eases [aoe [aoe 43. TRANSFERUL PRIN MEMBRANE ‘Un importat tn cin woe sobetns a cml merbeanre Sone a5 revit ca if pol dln de poten bembraelor c= Te Aces caml perm racer oor de ois potas, clo ‘Membrane eda - pee melamine webu oe tevez en tev pat alon sn formate in lide prs, trie de x tale fone, Medixmentle pore averse menbranel rin zine (taser pn) onl de ods, potas cl clr tamil pin canalele tence in func presonesonmots,Altemedicamene umecsisme ani oraz apie feces un anes pei i Recep remand unt x patra la: 1 esprl c caal nl forma int poten care dein un canalione ™ rerport aime forma dn protle tanamembranae atte connate in poten dinspee xls yeep culo cu protein G receptor in serpent) conn dot protein culate Dini ele, peteine Gc fancier actvenl sere se entie membrana dealt, fsblpusC,prteikinane,Aceste steep n ince meee ara. ge in roca ~ receptor intacllal nla asupe crore acfonean mle poslble(cocostrt armen! andogen! sopel orm ein, “nmin D). dat prune ell, este saben se faeet pe ADN a ‘Sn nei, aonind ca fico detranarpfe eps ne gee alte 444. NEUROTRANSMIFATORH (MEDIATORI CHIMICI) Legh fononae ite neuron unt tigate pin snap. La acest nivel clone neuroteensiitor (medion chime) tet portant ral lls Acjunie ular medics aoe in neers ne ‘rotanemiteror. Acs alone i tel siepaer (ature dite euon reannd rope if eros dels ur aaron ll sent Unie ssn parsing aot nivel nape eartanemitra ‘steacclinn pstmt spall, ee rol at snap preganglonse ‘etealing a cle psigeaglionare seein [> Cap = MEDICATIA SISTEMULUL NERVOS VEGETAL Insstemul eros ental ened ta Merete ~ emia nes sowasanite sap acto, ~ Gatesimicde:sordenlins (prdami) areas = dpaia (peecurenresporedreraling: ent sage dpaminergce fn sitet exespramal stem bie in plano De ott In ‘ue plaice eae seratransmitorl et tot dpaminas % arotonina -ideopanina = 517) ard anc In prodceren somal more repre TA nal vratr In proce minale ates ~ seidl guna aminouti(GABA)'aeonerl cn neotenic serene ihc ‘Cancers nzurtzensmiitoro sre ps importants firme: tiple Metca stipektnoniend, maf mera ies, medic. [it in ste de oe, sipahetcle polar meetin antiemetic din cue imiotrapel cet, toe daar ape dior oredr ‘deca nat at dome, Sshtnedenamitesimpatcomimetice (exp areola, fed ‘> abulol) simulerst arisen earotranmitorir dn domeall ‘plese nerves simp), Sobstanse namie perastopatcon a AN MARCRA, VEADINUS MANTA IRATLESE ‘Tbe 42. Neaotransnitoe (mediator chink) etree eactune sl aplatie famacoterapetie ee femrteee feet er [nce era [Snr ane [tee |e ar liana a a Frerticn| eects. citation, nee ion on wna ea |e. ips oe seat (de exempt, plocaping) simul active neuroranentitecor fin domi eine (al aistealsparasnpat). ec sul etic Indio aeiane sgn destiulare receptor i ror spec Satstnee denurite parasimpatcobtee (de exempt, sro), sub soe betbloante (de empl, propane) ebtanle nestle (de ‘rempl,corpromazins, haloperidol lap) a, dpa fe Boca letrouanmitelor peste cept speci Sula lied not ‘desu oscpne stage de inhib ceptor din tere pert 5, MEDICATIA SISTEMULUI NERVOS VEGETATIV (SNV) DDERINTTII WEXPLICATL ‘Ac alogons =n gener acne dametl ops doa see, ‘dou epane sa dood tare ie exemp, acont supa muscle ‘ital bree ervoae spats proveach mda (tues pup, ar (ne parasmpaiedetermind mio (ljrze pple) In frmseaiare In categorin anon se incl sbsanse cre ovnd abate pent roy ton sec a stiles pena acta ines, a ft Boca spe lor “onsen genera sistem ogae sau sistance an cea ene, neopets repro (de exempt mae ex a nth Jai— beso sora ete, - unt agi pari azeag mine ‘ul segiea e mene fes peea) I farmacadnam ae sgoit sat inte sbeailecar sind wnat per reap spe, ‘Peeve (aimala ate rn). ‘Sistem nervo vegeta sstemul nerves autonom, SAV) ee cl cae ssigr neni toe vicerlr (npn interne) andl, rata ede Le ato indepnndas ancien afr coon goal om JB talent din dou mart componente ~ etme impet altel ‘arampatc~ exe acionestt aapoist, uumind Abie is tae ogee ‘mayne menpoate, dau opae efector cre, deck au ecare © abs incre pts 1 5.1. SISTEMUL NERVOS SIMPATIC (ORTOSIMPATIC) ~ DOMENTUL ADRENERGIC se fort: prime nd de newt (stun intranasal): aaron venti cate sei In courele tere le side treo lobar; %6 ~ fle nervous (lite din axon aeetaraeron ae un ae inate cu nero dn gagnd simp parr (edu se Parle de anlion). Se umes: re preangonste Suan cacao Tide aerotansmiior in acest snaps ete acslclla snp find de Coline ~ a dol rad de nero: ce stun ganglia parser ‘vali (ace anglon se a nats dou apc clone ee raf epg in sting es ~ fel nervease (taal de eal de nd de neuen casa fre pesgangloarelang merger onane Neutra] ‘nace ed este noadrenlin, nape Srl spac de envelop ‘lor find ec sceerice “Tet din deni denen face pars - cox dou component ¥ me- uowupuenl, Ex sere entecceninel,sordrenalion areal, ta Ames. Sintra cetecalamindrparcurge unio nt dee ‘Toni on aminec > Dpamiat + Norden + Ade _RECEPTORII ADRENERGICI AI SISTEMULULNERVOS VEGETATIV SISUBSTANTELE DIN DOMENIUL ADRENERGIC ‘atelier sostnsbogene cu struct deamineyacfane a sopreoueinpatico mime. lelndepiaec unc de newrtranstows ‘aur lestell snp sant prodae de rmedsonpetenl gee ‘ur cu sacar ater Dinca fe pre serena, elise epintine i dopsmina Noradrenaling, deri adrenalin (epinefrn) dopmina se ies gl acionean prin intermatalreesporor street dinerenl nee ‘ell fermen ea ner vgn. Ace cet sem een "parle B98, Sear mind ci opi bine deli. ‘sn flint uno substan dn omen deep nee ef sete scone stp una sng ip de eet acne Agen ne Select se ca sectvat ok ations sp sl mer pie ep ‘or adrenerge determining, des, gee eendae (ened ins co ics 4 Receptor sf adrenergic sant stun tuna moscur ateile- Jordin circus sistem, ia mateltrn nee dn trac genoa moja adie sll Dee males sete erp! epee const arr inter stele, wat de eee Ta coe Inzona paral getourna; ml Prince sane cet ale "Teal 1 Receptor adenegie sagen farmaclogel care actionest sais napa lr nd ge) ne elro an ma \incuti nat chen pci Fipide[lncinrese [sl [Agile [Oberoi Jets lemrer [eimai | pete ee fc Finan [Tomi [Kenan ae veces Ja ee |e facia |Vammige [Renn [min (omer |e engl seretr | Sepemtne Since [pina pmo Saag [neg [Nemo ta sem eee, oe pa —— Ee (eee po lesan = fete | pein, en ease ene eaase a Same hoor ieee ee eres Sree ieee See eee Ses ee deere sunt catcolamicle (noradrenaline seis) care a ene ‘eset fnlfia fmetonatioa care sunt ail sete Receptor adeenergese en masculine la rte ‘epelmonare in maculata need din ac stints ne ep ‘Stmlae or etermint sacs plnor aes muses (ede usinesinal secre anlar abner eee nk ‘ce ein: dine roel depuis in apace. Exits # ep ‘iz arene naps ene trombone er cleo ust Schnee ft ali 2 renege unt ctecolace actan nse. Jet. Clonidine ro acne sev stagnate ep ‘ume enh spats, pled erate eneradenaln 1 Recepoet ett adrenergic sunt lala tn float mloeed est exe conductorl ims sma afi nee oe, Sule at produce ala, ceerea eae pli excare nor ett erro urate de sare desea Subst betel espe sn pe ‘et pin caecamine pede) eld, opeteeal(eprealin laboring seats evind ane ot, Receptor beta adeeerlc afin motcltrs etd «broker ‘ne ermal, Prin simul lo ae produce dae aur conde ese mic. ubsanlec eae demu acetr ee unt ade tila ciae nee) ein prin oust) ate mecicamenee cu select tnall apa rector bee? atenerge an ‘onli albueralSabutamel enter btn enero Ase frmacclogict Hoc al aestor receptor st ssane care pres erin de tualmine anv einer nerves pongangi. nae Inpiediind sejunesadreeglr,eerid~evdet~ en eos sianune ~All blocantl, producing asda se mn determin ce ‘ea TA sual adic vind elec snpertenay ot cn delang © Ipowastne postural Ace inden fecal, dere de eget ‘aminw, deri de imide, lean, cred abel pe. oan Alf. bloante a, esemenen fc soar Sunt epreentte Ae feilanin, erpamini yoink. ™ Belablocantele oui sods rel csi TA dio ‘etal ini ates introcre le cprnd rl ma un {euacune net propria al lel Ca eae sett pe ‘ete ental eetopso vid et portant et anhpeieste ‘Medicmentl cu acne adenergsimacts (pois) su loan ‘sotagons) aie lets repeat > Table S954 ‘ih. mcd cpr are ‘ith 3. Mean nla (a da doen i tnmusopd cone stg) feneaaoaasesentteer races aatacres rearaapeh conn ee oe nant steams sc Soman [” f e re a etter | Rips |r nt =p i a [sn = — fee = a == jaar ai fore n ss Sciam” |r Fareny faa sy [een poets eas | peeerd = = ae oases aster um [ee fe are ceo ssc, ae Fc [Prana [atte | tance Tarim cif sa sees [Scie oe fa rete fea [et fSareey —— fol i. [a Tempel [Peau ee : Inca. fase foe lp eben ats ~ [sini nls Pe [pace [mci mr : teem fem, ce Semen | fm i se Ee scoaban = EE fan emete |} te feat eo Hane face a haan (oa fa fe errr ea inner ate een Es Fartina reer face ose Stone Saeco a " pee ese iin ® w ‘ei uncanny ra SSHRC ‘coo oe rawwacovocie congue sel 3 eo pee Sa fa — Bes = ome te en fame (es [eee fan [ee [es — neste in gi ecm oe ae a Se ee mewn tome oe a Jee frp de Jp a cardi in ia = aS ee [eae axe ome fee (oe — fear ese Sas ieee ee Soe st oe = — fs. ees fe EE ses io sae [stnco - fos eee fo = Ss meet howe ela eee |S en FS Es PPS [ram eee Se fam (EES. ease oe Fs are cn a ae =) = (Se, ee (ces Fee, peseee | SES fe so sc |e Sin Sen bs: = Ese aes [Beast [HA Profs | Carona jewel ta le” |i [ee Ea S| Se ee oe nics hina EE eee, as. (me ft ee rine [ee [si fi aan cee Sho ee ce. | Sa ee ce | Eee Be] ee , =) fee a te imeereg peor ee ee = ie ao sa fe = ie hee eee | Sse see ea sat ce ‘52, SISTEMUL PARASIMPATIC - DOMENTUL ‘COLINERGIC stat ie primal isd de ner ct nme (et nero) prasinptt din roc eb esncl pen Sb ran) en o> ‘Seapets Fic one van se ea ag ‘edd cet meno tone efector Sun epee [Els lvl sip es esron din orgs, neurovansiorl e ‘etflne Dey spec ot noerpr: al doen ed de searns rp in pclae sunt santa pris Inmet sro ratte, owen forte sues sberfce pla dele est dln rind de nett Last ie, neutunansiord ese tot ctl find (et yor tt desiapealineges 1 eh opr ictus aon pin ered cepa ee Sok pt ‘recycler oxen nlc Ms copa ol bp ci gn ns eg pean Shahipdiaeytnenbmaptines : : tn 2 cON nc ero sc, aye ee SNC pont epi ping fine peal 5.21. MBDICAMENTE PARASDMPATICOMIMETICE {cn stim- lend aupen receptor clare) [N78] "a pratserapi se flea: ero substan prelpatiam- Sen actioling couse srt oc (Mdhol Ee, inane a nari oles ei i ola api be ine ‘se ge ats deem ‘eam pcrpinn led dn plant ibcpu bho lt faloog fm sco, peat «cine seldeex pez ocuae 9 mie ‘elind deta de astra, plcarpiasepones ep ma idan {Peale steric, ploarin (Bind fore tne) ete nde mama cx ‘Sdot in iter roping plane seanace 15.2.2. MEDICAMENTR ANTICOLINESTERAZICE Prin acts callers ele let peasenpacomimetic. Evia ia ogeinm mnt colnereraa droll Surplus ber deacclint (neurtranaittora inser parsinpte) menial cbs flog tain imeseraza xe oc de aque bse, me smcolinesterani, ae ol produce aver rn acumelsres wna ‘nt de sceteain.Dine ace ep retin (nei), mediante clin olalolgie petra ‘etna gcomull pe cl sister o maroc) main {nde in iti cot ew arin plate solace: “"Neosigmina ionin,proigmind, ead face stinalete supra muscle nde sate Gin nternel receptor masons) ee {medicament ici inns intestinal ave nae postopera Postpartum, in miseni in atx co btanjcraianeanepaa- ‘Bot (abort, galt). “Tl cnet hide be ce ce ec ct dee ‘ai pn osetia 9 seule nace de ctl. Ae {ernst insane etter (paton, ain feed epi abs somal) 5:23 MEDICAMENTE PARASIMPATICOLITICE (cx tins nitric spe ceptor cline) "seat antagonist fe parsinpsicomeic, pia blcazea secs cline msec “Atropina een sles con in lal lana (rtguna = Ange ladon; mises = Hyetames rier: lua sau cla = Datars ramon net anspancn ee calin lcal aioe ‘rele brie snarl nits eu anne (iseo- ‘apie orenleafrate, gue dept europa); nance pene elec denn pecare produce Scopomin al eleod conan ae in malar ete teat ea sedative de agi pabomotone xm forms de comput semis "lca In call inten are erie ale rine. 53, SUBSTANTELE GANGLIONARE Aces scionenk supra ganglonor vege perc (2 NU se oa ‘ads eu gun lime), erwin apa neacransmftorr dea vel sper ganglosre Coping sbatantle aicatnic subtafle cnnelloplegce. sa. MtcommaceLe ‘Neoin epeznanta scl grape, xe un aed care etre in frame det at odes toc: Plrandee ln organs Se ‘rode pia ible Sn Se gar I aa ini, coos sunleeh ” sermon x en opener clberae de eteclamine da medonprarenal, ia unle zane rellenogene in SNC in cet lb placa eon mioi din ge nda fk derma ae oemant. Esto ints eat ca ‘tin nfs pin lore, rent, vse, pone, api fa ferme poe spar cova ponte suven our pl parle espto= ‘ntti ric nin eto fra de ncaa bogs ‘ounce notin podoce dependent tolerant [> Cap.33 ~ DROGURL, SSTUPEFANTE, NAROOTICE) fect pci ntalen in timp:bron- {8 cone tbipcs broabopaamopate bxtrctndcroni, tombaret biter pin soe de gangrent a memreleineioure cera eever- tetertcundr de ible ino sere de fun. adopt chemi ‘ronnie ocd aa cane pulmonar cancer de ede ria cerpmvodolezl 532. GANGLIOPLEGICELE este btn cv trite i, termi parle aolon lor vp Se proce a adere bata» estan rer, hnpindse [Beap i liptinie Se secs const pt ew pic een de ‘Sink In erapeatel sexs nd un sagur modiarent lst dn aceart ‘Stgori iadst patra cease ue sede! portant TA), tn present Sondinue SECTIUNEA a II-a GHID DE FARMACOTERAPIE ‘6. MEDICATIA APARATULUI DIGESTIV DDEFINTTHT SL EXPLICATIE ‘Bea Alster = port presen! ven n cares produce o rfc praia soar ercile Se mane prin bur de menor, dezaien {aretemporo pal ncaa dents, epee personal Inns esimertr endemansr et xi ~ prin poezde elie — posbilatn cll toe lll, ptuns I rani, ape sear Stele ‘nj = pepe care scone ce narovanmerviad fl pe opera rer late, rere earendocing et Sepia” ‘ali —n plea nervosse glee exein ale cat gsrointsioa ‘lab r= tact pre pu-gatv cre determin pee 0 dnt avr de ule gastroduodenal Se eal Ite ete ‘oc ea duodenal latte mucus protector care acoper acs ep ‘nda pon Sedepstat rin eae ca mole bacterin dice vei imal prin psed macoas nu mete achimiceindecle ‘tc derisr al vel» mug need alot In peeled rina, scat pia stemul purasinpate care, contacts, determin gen ‘el rine (Se scl mich) ‘Soma Zollnger liz = indrom creer pia spar de tues ls cshllor Langerhans din coda pancreas, Aces ~ sre in bu enh gutent~ determi sparta deere multe redvante nstomac ‘i dsoden Produc hierdie, dae ppt, vst, daze sare de era. a ANE MANCRAS, VLADINURAUARTA MINAS 6.1. MEDIGATIA ANTIACIDA §1 ANTIULCEROASA (61. ANTIACIDE (4024) Noten i src pp it inate als nde atta ier exp de rela He sunt preety ‘eae aie srt ner Adinieraten lor ete expe ae ral 6111, Compal de maguerin ‘Copeind ond de mages (Mapai ws); hidaxd de magne ar ‘boat baie de mages tact de magni cst medicament es (alacant acidal cova in weal pri f pla, a fet aa Sok Contant n spent su, na de sun ures abdominle ‘enn eps 61.2, Compa! deslamina ‘Sunteeprevea pe fon de alumni hides de alumina sec 1 prop loge el nin peut cond pct). Ina de ce tulannc acfonean x artingent descongestonat al macs patie # ‘adel itstinal Conraaci pencth cu consipa rs ‘ne Ahetmer 64.13.Compuyide cae ‘ia sect ere arte ctrbonatld clea (Anal) ~ comp sate Beaming antirel, 1.14. combinai destin stmgnerin | ‘repr de cet eat une Un ems alse arco a fail hance espace pedo Dine de amit i Amogal gl de dod ests hdd be mae coe consents) i prcartocalm’: carbons de clu + carbonate mea rsa de smaguei (compra), fi Seal”: dad de sli + idea de mojoeia(cmprinats mice) Sct slo de magoenia + hdd de shun (comprise). (61.15, Combing de nace ca antopstie Gamogaatia" hiro de sumiant + exact de belladonna se. (compinat) Arcee cote pal deo al muscu eed i. ‘Binowel seca de acd acd: Ob: peprtl a al paren name ‘Snoral metcamenelor in Romi in sla 161.16. Bietbonata soda (HCO), uh erm de plbere sn com plat ese ual dae xem pti ainsi ache ste ‘nick In doe mar pote rodacesleosk. (61.17. Combinai de antiacideca bicarbonate da = Prepare Ulerott”(Comptinut)caoine sata base de Bast ‘carbon bz de magn, betbooat de so, cgi de eon, cnt de ‘Ghimis, Seadminisvena dps ese 61.1.8. Combinai dated cu antilataante ~ Bpicoa” exe osaspenle In compo ces int hdr de eum- um gl roel de magnets dimen (smticn). Dinetcona cre Inte tn compari peepratl! Sab Simpler) cole esis bdo ‘na pin Inder peor din itn (61.2. ANTIHISTAMINICE H, (402 BA} Aczte mediameste ainens prin Hace sc eeporir is tain, dn mucosa, diode secede cli, ‘tmponets important esol asic area rnp ol fiat a Producers itetnere cera. Cael lite anitsemn lcante Slevecepoor Hn: Cimetiind (Hste),- compra oles ~ Famotidind Famoda’;Quamate),"compriite fle x puber oi sls penta preprints = Ninatin (Asi Noi”) cps Sle jects ~ Manitidind (Arata Zantac®) = comprise einai, Farmacoterple Ite ntmtnlorH, lee gst doen sofg de refs sndrom Zolger ison; preveies ulcer in tt ‘mente cu AINS;preveienhemorgior digi sapere ncaa optics Glin uselesneren chirp Farmaco Re vee erp tne ae fle, ate- si smnolenh ml pelea aera, (61.3. INHIBITOARE ALE POMPEI DE PROTOM [402 BC] Acetomedlamente scones blocnd ns ie faces cpr dzhidroge-on sel impede sport seo cit celie froare fecdeonadre: “nda: ee gatrodvodeoa; eats bate Hoar poi ‘oad eu gsvoeapansndromZollnge Eso; leis gated Tell 62]- asstive brian cre aeonea prin ef mae (de nme) ‘supra caput eer a ncaa led de pars “native de contac cre tenses pert ternal pri itarea ‘macoase Aun ampotant nace mean sel anche Ss sein franel rcele de Senna, dre 9 prepuate de ined br ‘sce, pleosult dso; ™ lzative de Ylum, ze sunt pasar idole and proretaen deze a ps ind af vom ont nesta Tap, moran constena Boll eal: semi de sla, “ibe 62. Clason late o Dessmirconercle [Oba Tae [Ulcers Par" is [mar — asa Se er ete abate Penta ‘une si fee Cees emis mpfr ead got aa a a a “ pr ea Rape lominederae [Sectmnucrscos [wean as Rasa exvede|cipabol) mec dei ont. fee Mer Og: iepeemaro rod iets eee dna see Dapp) a live act ar acta pale [as pal, Coma aor! [enter Pease tu ieee HOE (coosipaa hab) sou em detent de tmobile pean pas * grea petro eramene aloe ea endotcopice (de exempl elano- ‘copia le abla die rg preopertore in nerve pf ‘igus le operat Ul ds para ciinat nod spec inde beste ert de deere hemos ica tl psepe ‘aor. Lacuna se tlizazsn encfopatin pte, dere sede ler bectean produit de smonie (repre amo tasnge te ‘espns deenomencle neuopice dn come hepte. ‘intraindit abdomendl net inusind spent Sith Alef, ta aged, lave pot rovoca perfor, ocasn nein. pert ‘recabdominale eas nprcrat var epee reo e ‘morph. Lacan te cotrndeiinpacoaee ileal roe 65. ANTIDIAREICE [A 07] Aen terpetic din scen prop acionent fe tmpotv ore! bate ene pstogene in wet testinal bind perianal eset filinti pede hidroeculice ae we prode prin te. Tot sce Inedicamentesesdmisiatesl pe cl or 5.1, MEDICATIA ANTINFSCTIOASA A TUBULUI DIGEST (407 A} Princip germen! bce ae provoucinfecldgetve Se fr mide gutroentere fe sob fd de enercate seats rena sarin fuel enerobacteriaceso: bat Cl (cherie ol) dere tail pe ‘opene Ate, ihe cl apace pte i ors nvr spot 2 etn! gos uman)s bel Prue spi Salmond (erie ‘Speci; Sigel iets); Ysa entero, Dale ul fa a {© Conpyoace fc Campylobacter ont Denes de recent a Ua ‘ment ete Corio dif eare rodeo eateraclti maromerbreoast static ju et seas ie els al ni, ua a "ancomisns pel rl Antibes chiitraplce wan inf le tuba dg ‘A et carceris petal antbntran ca de ar page nestor ore ed unl in neti ~ Warming (Noemie) ee un ano frac cami nea sorta din inten. Dept: goes sew de eiogle acer -amezoefe:se presi si frm dcop mae ~ Nifurni Ereeary) deriva n note, nesbrab in ne ‘saree nde. armacopfe: iat sab for dap, ~ arazallon etc ines eatrbacerscenlogl ior poo ‘re Imonenintl cons in ale area vara. Compete AN MANCEAN, VLAD MANTA MIKAILESCU ~ Clorohinaldl (Sopra) lect anor entercacll rips anor eve prtooere rer, Merorgntsme entire ‘Actanes acters se azar pe Feomaenl de compete dine difertle ‘oto de gament (prot de pigen. = Benforing et us prodas cae nin rs make apn de ae ich ‘vi Acjonent mening exible defected nein, [ein echtrind ore ctean feta de alti or com tind ele gemeninepatoge’ (shri cal ptogen, Slane). Farmaco sole bv i fscoae ca dep dotoe Sucharomyees boule (Eater) eeu fungus eu acne Bi de uncle pci batten lv. cai gstromnre ait bem, ret fostantbioce Rent aera prose menor, ng (cee ext sb fr de ll vt) ponte deve! da agent tape, gent atop, detemined olafeie nice severh (52. MEDICATIA ADSORBANTA (A 078} ‘cate mediemeate a 0 bun disperse prior alone peo sobs (NU abet) germendorptogent + toxiadarEncterene Produflor de depadareasbstanjlr cs ete oie in nest, tof aa [rand af etimoa pin cau, De goat ch adsorbantlentestige NU sit ‘labels nun media hid ~ Cine medicinal (Carlo medias) ob form de aber cape ‘steindcat in emule eae intestinal fer beri ~ Diosmecta (Seca) exe agit sorb form de pulbere ia plc Conn aestora se resapendd nap (NU esteslbdH). Ina fine de oie lg sndroma de nein abl (53 INHIBITORIL DE ENKEEALINAZA [4.07 x) ‘ Enkfiliea esto cai cederadst enfin Aes st ne rotenone gan, le nell abl digest un later sting ‘iors pet elector Inset fl ental ee dare tmp tc perdede hidroectraise importante car a lof patentertele feteoalle seve = Raceeadote (Hira) est inhiboe de nfl ntierte etn antiares Se pres a plere pnts sion cpele (5:4 ANTIPROPULSIVE [4.07 ‘Action prin seidera pests intial (ert cnapet) = Loperamid (imodium’) ee nda le conceal pun nel seat (numa! in ne de persistent oe re intent, ni ee mel). Conrad in enterocolitecusoane anginlete cop ‘visa sub ys at (poste produc parle itt = spare). ‘amine rl 666, ANTIINFLAMATOARE INTESTINALE [A 07 5] In sce gop ine medicament tite petra cambteces wor bal Infamstot rie, Bs elo Infeiont le unocona sna [NU ote vot, pr amare, dere entroait sete de clog mera, clean rote sau pars (onde ert ni en ntamet elope signe) cde bl ca abst imunelergl cree manent pein proce inflamato ole persistent relante ou iftea maces! fod fed le tana intestinal ae senanloe De nt cage erpentc fos n acest fein uo sherpa eh sauces nlp ‘ling eh execzes scp ot ingest une gs Calon, Dine antaaatearl nese unl prin secrete tetera pra mace nese. Liat sth forma epee [eliberat ual in nes ete mtn bal Cro une cate srenice ~ Sustain (Salaropea” ~ cmprimat nate groves) te un deriva al acidll amiga (il Saminaiie = meslia) pe faze elbereat in clon. Farmaco: exe art In oa Crh ete lia ulcer hemoragi colt rosie Prods rat! bers meg pa ln trmbectopenie copa fee tie apa etl pacts “= Mesalarnt (acd anos Sala), Se pei nf vo ute persuade oi oe: der entero sopostons, ‘spe recl spams pena amie ites, Ace alee ea ‘slfisaiin. Farmactoiclg: poate roduc resi de percent let intestials oni reverb ‘Un prods dis apktar lot ce ennfatr inten exe Propolis (Otprosept ee se presns ab form de extract mone spore ‘Adminisares stellata eu int ears de etre ‘ele anorectal 67. PREPARATE CU ENZIME DIGESTIVE [4 09] Ace prepa con pipe enzme car —n sod ater — part ‘pila procul dedgeie Proto ant late ands net ‘Semoecule ma me de ce pepin din cl pei aoa sleet fr ‘orig aminoacid etn emotping cae ant pene 101 proce, Gun (ip) ante set hid inde in gi Feat geld eden pion panes ndele ‘Salta Gelies de pon ent ref dato le ecm cata moe econ dec ana. Acat en inh econ ot in ual pent Dict propane con eine ‘Prenton psa compose reser gs id asic froctcl oon (¢ wld nine), oat Sopot Eines puso carro mcor domiol rept Toei tdeneat pce Dig coie parc c ace prot, pli fa Ind por evtct de bt de bow hens (Ape NU ee 23 Bets arteries ant ghia eat) Fea cone ie psc ale once, emia ‘ah detouaagpecoth = ambi one cine pncreti, i Sebo a bem 2 Lie nb or deer ptt "Paeemet cone to ped anak, 1 moge cone pop, Hs tek rte i doce ane 68, MEDICAMENTE PENTRU AFECTIUNI ‘HEPATOBILIARE [4 05} (6.1, PREPARATE CU ACEI BILIARE ‘cote medeaente nan cle cledtekinel le farts: ebondplipdeoracolestrlul a vaninlr pooh (A,D. EE . ald wrrodexiale (Ufa espe & comprinat) isaresfvrene drres cela cede necliial ear m ‘epic 10 an dare nda aii bien cael cle ‘oleae indeplnes cst cond (682, PREPARATE CUSARURIILIARE Gach djs contd a deb + eat deat ‘epumind + le de ment lef spt tee shal Wa nai spurte leer ilar; celeste conic (683, PREPARATE CU ACID DEHIDROCOLIC = Hobilin’ comprinate. Indep penta en) bar posopertor pera eiarscokeatogre, 6.84 PREPARATE PE BAZA DE TERPENE ‘ects sunt wears ote cafe elec entail tinea late; cles protec uatueatl ee late ~ Blick copaule ganoaseetrosaase coin mento, mene nea, booed cea. cafe, "Towadhal cape sain ptr Compon ndai rape see eemintte 6.3, MEDICAMENTE HEPATOPROTECTOARE [405 8) A0S €) ‘vac ull protector spelt pats, nn a es nor rine ac amnion cave des rene inte hep ~The bs de rininy amon spl rl asin hepa ArgnintSorbial-solueperssbib x Comin sce dol bane mt ocala un polio! erat din gcos rence ener Uefa) pete natn heptane ge peomonene. "Pers decid amar apatetoet~ fol psc sine ent ££ Piv.copinnd ed amps ¢ nos, Aorta pe bn enc gata Mag = Sl pet sire x nau ~ Pe baat de meting mined eel x acne top de salar fans «hoch Maar a oad ‘Bena npr, amin 3 hy 8, PP aa Rpt ate one stator ep: Meigen ™ Pe bal dealin, cee un ase de el favo cu acne de ste membre! etch Siar oop be Pot onc innate copes tore Aan plod pena fmbace accor hepatic. "pet de mest de plat: Hepa Plants ps coninod xt de br aro ae pate Inthe oly ed ‘otc bilae Pett effet ann ra merle ce lure a ft Upto. nd pa ral ce hepa sso ep clea Preprint rp: tne fore" capul coated pe cen amine 3,.8)8,, PPE “pct B12 ~ cape mol coninin ope ele age lnc, eld rte tani din comple B exact de share 7. MEDICAMENTE PENTRU BOLI DE NUTRITIE SI METABOLISM DDEFINITH SLEXPLICATIL Factor cde compare = 13 fc care at sumer del (Srinoge- ul) pnt I actor subatoralBines = FSP) pear patp ie feel ae ae proces de eagle [> Caps MEDICATIA SANGELUT] Inala fon = NPH (ere Pratne Hager) - ind = ning coaciune intermedius fom de spent spas tamponade nin ‘ine gproumint. Are duntsdescune ede de 16a 7.1 MEDICAMENTE ANTIOBEZITATE [4.08] ‘Obert e defy can nes ponder pin etre shane et Iu acpe. Cree se elaest pen epunere tn supine d rim netre In xl acs jst Stbliven ped de obetate wfc rn clues Indl demas corporal (IMC) Is eng AM = body mare), Pei, ‘valor orl ae ses ie In aie devi, ree corporal me 4 “D7 Subic prada obstat fin nie demask compra fnicesrea [acl Jicin ncn sada anemone bese de obec de [seamen gudlt [pan lew Demeaont en tetamennl bea ll precip vine dt hipo- calc, hippies, hop hosed, precumrepl e Ws ‘de mere prin combatees sonar Meda sunt secur 77 MEDICAMENT ANTIOBEZITATE CU ACTIUNE CENTRALA Sunt substan rade sacar anti ¥cionend pia rei cece peti ~"Anfopeamen (Regenon’) cu admins rl = Sittin (Minimaci’ ste tn plus hibit al eecapet nore renlinelSetenine stad elt antpran Previt erste ‘fever: aa cardnce, HA, ena, efile, eee preset Conran: perscane eu tsp, nce cr, el a hepa TA, AVC, hpertdism,pesoane ce ira sub Sal peste 65 den Adina oc, 7.1.2, MEDICAMENTE ANTIOBEZITATE CU ACTIUNE PERIFERICA api Poe ind pe de cee dey a, ~ Orisa cx mina or 72. MEDICAMENTE ANTIDIABETICE [A 10] 72 INSULINE $1 ANALOGI INSULIN [A204] Insulin ste un hormin cu srorrt poietic, produ de elle icons prcressliNamce et derir deli Langerhans cae rt [pupae ces ele Decopert dessert roma Nise Pec a ce "a mumi-oast) fost di pn remeber adi Basing Bester au pnt prema Nobel t- da enaen aa “Acne pncpl nal! ee de eee» lem pl everiares ptsunden gc in ee stinlaren metal Act cis ‘fe elazt pri eure nse! de receptor pci spe membraad ‘lr a as nals achonead pia eyes gegenogeez! hops (Gxt de eepoxtares glace in es 9 mines pcopooin! (alel scmpunet gegen molec de aces care unt irmief ies ap lion ete deci un hormon hipolemiat. Ain stagons ns line ou glaesgonal thorn secret de ede ain nse Langerhans) drenlinn ormon secret de medal ander supa) to Seri oes asta = ce rede cortcoupeseenal, pecs wet de Sloe Ace sat hormon perl mia, opeulne Ate, NU ete cre ps abel a she Nie vob aside abr Sec ine se eign apn mci etc nt de ‘nari eer nfo Ceara peo (Ge ep edt in) eis a mes nl nd seen eae ‘Danes ornare Concerned sgn cia tra = 70.110 magi = So analog erchdekee «lees penn et nc ee exp ceri coc Gece ng Se Silo noo nase oo ompance naa: pre ee nin el ‘Sc pope tingle pact S08 a tered Ton out ee ira pn en cy prlowsdac pnd cl ‘Stes eal esta Deo so ened pte 80 yoga ena” ‘Tuc ce epg spe cnn hc in one od noma NU bul et) Dict cet to ne nce pod dena st eo inure a nt lela cere ser peri spirnd cocotst ‘ove de ture ebuie (cos ces, permanent. Rll line odnatat a meee epi de selene on ‘or etn nc dnt per cbt “td itp nelnndependet ce rw copes ie a ‘ream acea pls ceo conpere cig tbr away nonaninaspensn resp cvot pte de ‘ettntntaeral seta pets opener ala eles orn pce Fig. Goce tna oe radis ponte va rnpaTOOIO 106 To epee inline uae (clean itemedin lem) 4 nmlne panda (elon acne rapid). Conn ertlor ‘pur de vio nose in tatient ns standards do valor de ‘vind sa de 10a Inetares inline! = ae Bec sein pratt (Ge eis in dvisiant de, Ge cu pen. Aces unt ip den stream ries wal show preva cu coin Un cary ‘nina deere dona dori prin acionara unr batuae, Vist ‘Se pae cal pompelr de inlink compstrante, care rane a rapoet ‘lle lene! velit oerape bal panda ini con ‘dsc dein NU pot exits frme de ednilstre orl nse (a Iie descompreede uel gti) Th piven, flour ermine ater einai, elite pia ‘otetologe pe bot denn uman, Be pin pocedee de sense: 72.1, Ivan sci roid, ntate ter, cae spare ‘ul ovinder pane ect lor ~ dup adminstea ssc ‘Raa pn tlre pi 1/4 ~ Lr) anger in scar np (0-40) 8 peal (concentra prt de i. concer act ciae de ‘Sar dural (6 Bore) Din acest mat ore inline irene eel or peu 30 de inte ones mesloc ponte Aminsraren Lica fcr nual nena decom diabetic (cares de dod rls comt perosmolar com acdo coi) sare peace le un fit ined, ar de drat al est Din gop nape opie fc pte: = Actepid HOM Peal Sb orn de sla njectb 100 wy ener (ponte de injector de tou) sul Regular (Hamelin Reuss ome de preaetare, Fig Dapeai oper pemundminsewenuee AN MARCEAY, VADER ATA MAIC 72.1.2, Analog al imi cache xpd, sind cle san pranne Re analog st produ pra thle de ADS reco ‘inant cherie en gaa seat propria inane pie Dine slemenonin Incl isprom (Huma. form esol pen ch pen ei ™ Inslnd apart (Novorapld”Pexpen, sue injec a 10 wh? aly pena ‘De nota logue forme deal capo mln ‘ui de geo nest de com dabei) sunt aude suit apd ‘lg sine cone apse (NU ssuspenleToatcldae pr oume de preveatr se line se admiiseaeh nual se 72.1.3, line ca afinne intermedi lent ott er, ape- fis ulnar bale La sce, dup adiminitrares sy nts st Iecepela 20m, penbulplamntc eels € req dusts dean setinde 151016 ore fn cal nlinloe co acne Itermediar unt cee dout {jeri sn 24 or NU ere permis intodsoers ta soator inning Din sco gro ic pre: ~ Humuls°N csoinnd rfid suspense injects 2 100, ‘ui sipenars = Insaltard- suspense inject «10 Lg pen-ur xt analog nlp es acne intermedia 72.14, Insulin cu aun peta (alta, notse ce ea U, spain nelle bua, Aion lot acepe lain = 2 ore def etre, poate ania 68 or, dura actives de 4 oe cha ma mt Se ‘Sinsenet eoigur da 24 or a ulna inp ae lose de pete ‘op analog eile cw cine plang ~ Inulin larg Lanta), ci injectb 100m fens (scout 1 Inala detemie(Leverie), soi ijecta 100 li tos Injector Levee Hex Pens 100 adel Adcsar ir dat in 2 or. 72.15. toetinete premise unloiicu bt api ocine pretan- teri cle maior vanes tart, Sant combate a cl acon chino ins rap un avd artnet da eras ee ett seated pl dar pest pk a2 ore, Dnt acest pepe = Truman” 8 (3070, comin 30% sli repr +70 aan ‘ns prec eo susprse ject 100 was 108 “Tel 72 Clsiiaresinslineoe penal lor carter Fpl deinntint [Denamict [Apel [Dura de acione [omee (pela) | apiece Is lente panne [Beenie [eongecee ase scanned [acrpiaion —[ootie cet [eee [natant [erat [Sedat [ate Jectinern [nowt [Satie ese nen teoke [ernie [Spe |io6er csc mince foatite oe ere ninedeigecme [ME te sant gipat ionge dtd ded Ang wn stn pe frocegt [lindane [scien [tA eo (toni tunatr ious ieee dr "mata operat, ie npr [Mima wiping pens nga Neomneaae (omar [onde [unten ct fan de [Seal MS [nde cous | pce te Jeon epcarca (nacanr mated noc, [ iad fins [uanranane ose lps |umcarrapeng [beeps Melingscounie (naga feat det ltpoemelde [nacetrapne [Soret eteupena sn pu) tegen ~ Humalog Mie (st insling ep) samen nel 10m ~ Novomi” (inulin sparta), sspeni jel 109i sipen preamp “Mica uspense inject «100 ui ape cantina nee componente ta dere propo Mstard" 10 HM = inl p10 “aig ents 90; Mitr 29 HM = inslin apil 208 + in leh 109 incur iach de sopradoare a nse de apa poem sensetve (rept png in cate gavel com polenta ‘nent ea eal se er ub coat persaent(nonitorzre)glcemi ‘Astin seat done pone etn de oar aden Apart eompute a, mut ghcometrs, ee aprosnali deform mines ans eon ‘elle Sino band serath co pcr desing boleeal apart cosas in cteveserunde lczmiaO alone dese re ‘dorares hemoglobin conse din hemat(Hb A) sre creer ele ennai penta ies de acne nine (aezes normals = Hb A, {6846-624 din total) Determinre gcoarel dara lace! tn ‘5 mn exe nectar In cal els endo enone Tn abnor tre eaeare value inde crete ceespanatoae x cos din asm (Gere care detrint mire parle gece). ‘enn de administrate asin in teaser medal) Injecere insulin se esc sbeatanat pesindas pide ine dook etal tc texte iguana el ma prunde In mse Se lege Joel de ijcare cu compress tr uo amu i past Balope ster Rees pote abe fe aleol de 70 data eb epi fu ing pnd tuck prec denarece soll nactvens selina. Act v2 svete ena de spotimate 4" cde lanl peli Zone delat or Sera den inectien al al: prima jee Sein rene xen = ‘ul bata dows in egianes eter al pent eon erat 1 peste abdominal armas olan teal in partes opus pete ‘AEbesced pe rpc cad ued comp nl deeper 8 ‘lene cope; 9 repre fers (abet, NU tn pl ser) ore aa repane esd (oes). Asal eit formate ioe nol I pod care a isa apart pl numeral ine casa pe care Tete inal Reloads de sdminsrateneline pet cle cy anes rap sunt de elo pe 72d oe inten meso principe pests ‘le cu sce intermedia de dot oelp cu 17 dot taltestdoak ese importante, diner te cit de apraxia 2 oe pen tw insulin priate: sings injec pe neu 1 or inten mee de pins. La abies dotelor densa eine Seams dale pci eerie de wel pe atc guametra 722 ANTIDIABETICE (HIPOGLICEMIANTE) ORALE (2 108), Antdabete oles wien ip ratametal ihe sabart i 2 sonitlsadepenent, den dabei aha lair de peste 40 de "evant aetcnandtn dae barat | (Gabe insinoepende, Innit cop adlsceny tines. In anu sta (coma bt abet hart imo ie infos rei chrurpete) pogeemian te rl sot contain nace perio peso ensline. 72.2. Selfmieaniibetice ‘Aes snt dete de alfentanil mart ip 2, onialindpendent Ele acioneet pis dean nin exe nce Iu in nl angen rn dinars papel Diese. ‘dae aiatie mentions ~ Tofbatamida, cre este 9 sulmid antidiabetic poglieans, setonind pin stale secret pancreas de inlined meek 4: 610 oe Contin: abe abr vend, bet ntl de aco et, dae In peroae cx fb cu inf actin, cn, ‘in inset hepatic, iene earl eas: hpogicemie rst. pga carey, er cleat anemia econ em boctopeneAdaistar oan 2-3 rite ne, ~ Gibenclamid: ministre orl 12 pie lc 1-2 inane demas ™ Glide ral tn 1-2 pie es, 1520 de rite ae ‘atede aes ~ Gilded disse ora propre de olla; = Glimepieid: seine at pd pipe 7222. Bigunide Aes acionets Mac aba intestinal a Jucuc snd ne cogicopnen produceen de uct in ergarsm din amis, pit on ‘omit nde ec metab), slain engeols elerce de pont ‘i gcopoul eps i muc). = Medormin (Digun"; Meguan) et cea lit ign Sad- ‘inistretora f23 pie in impala dopa mete nde api nl set sar soca beatae. Continent eri person ley lone crdie, hepatic so eal cdot metabolic, coma dete, "Exit pepe aracete i eae se arcs meta se slamide siitetice sn meormin caddie, 17223. Tazliindione (Gitta) ‘Acre white alone send rene (ick Mocre fcll) ‘densa instal mascot aor ate cel sant cumedormin.Mexionim nace gr ™ Rosightazonsdminiias oto -2 prizes, = Progltazon: sinister ne singrd pi nick 72.24. Glipine Sint sbstane cae pia ohare nartorenine produc cregeren nor hoon enon eft iplemiant Aces boon (pei pia pote ppt ilinatop dependot de cnt) actena ere dela ‘ns ae nt ioglcemians) locket aerepade can rete - pealzead enin arelshdee gem, Dine gptne enon: 7 Salpin, admis oa sagt dpe 7225.Glinide ‘ste neice tial scr de alo la alll -panees- ‘he, Menon “nepali (Novonorm): admire ri cu 1018 inate rasa Scie nee pine Se teal deren ce melo Important, Tiel neeprat a rei hot coe aun tte ‘neat cx tse, ts slimetart ae unr fndamentl a meee ‘oegenetha ier sary el ct blnaal st apostate unl tet epi de cen oral tn rte compa Dietoerapla inborn leet cmane pen mice pr de de, ar resin deren nunc de tpl ibe deve bolo 73: MEDICATIA HIPOLIPEMIANTA [C 10] _Mediamentl din acnst grup a ines ds cde concent is deo (= pel) earn reset in bed pelle plas ania. ee pent pode ein con mio ce sage (ihe sie) fet conal esc en eps ar nota ist- Fitena¢hsclsesons ein mae pent perl edocs Fein rau corde str pe pine srl (seen sone) © ck een tan et conc Shon depo epee de ‘Ethel qinpepe sr Scar Dime ilo ova dt [Seance png 130 on gine ri pigeon Ha ae [ed care ce lingo propre esa, ean con “i pens ier accepts al de oper va fer conch favoria py poses de wont rae fn une que suns mio (ge cree ch te ete Tn cisfe=cabcr) pose but ere de pve: rte oot ‘hermes na cbs proce sc (AVE) ‘Shem depres persis il degre oscil ‘a find wines dane pcpemine inlcude In mje ror pagent parle pl adores, 75.1 STATINELE ‘Aefoness ri inbares une enn, ido me tar cso A (GING Co A)-educans, cate prt asters clase Inet Pin cut cine coleseralemla Sadia Speclacianee cea mal ateogent 24 cclesteroll rt), cre ese LDL-clesteral (= low deny poten ‘ole: Dine tine meno: ~ Simvastatin Simco”: Zocor) caret a! a hperclexersemle sibipestipidese a bola cubypas coronaria, nein aaa cr (av) theme. Conan seca; isan hepa. Adminisre ont 732. mBRATI Action scr ieee din plasm cca faines eco lesterol antisterogent (cll bur) care ete MDL elec = igh ety Upoprota cher, Sut contin in asin ln nse hepsi Dine bra amin: Benatar or = Revoir (Lipa Lipo": deiner orl, 73.3, ACIDUL NICOTINIC # DERIVATIISAE Aetioett send wierd din sr eeciog actioned clea sntateope ™ Aelalnosini (tana) inhib elbrrs deca ri di fs ‘ulodipos Admnstare ori ‘Aeipimox(Olbetan) ete inc! in biperpopretenemla ip I ip I Adminerue oa 7.4, DBRIVATI DE ACIZEGRASITIP OMBGA 3 ~ Omacor: te dita prevenices ecundh nch de oead Admineta oa. 74, VETAMINE [A 11] (Clasicares natural itamineor le mparten otgrpe: amie oslible vitae hidovlble Ta setae dal fico iin ke fare fea vitsaele~ au un mporat ro ficial eid in cat "Ap mie. Indl armaceutcs moder seit cue dite vaste lporlbil te disponbieyconsmaie stn ora dos Dia a teddies vor pls, ah clasesrs or aural Tbe 73 ‘CRN Mactan, VLAD IMRAUNTAnRAILESCU “eal 73, Chsicarea natural yamindlor (A 1] FUNCTIILE VITAMINELOR IN ORGANISM gi FARMACOTERAPIA CU VITAMINE ~ Vitamin A (etna est vaio nto, in compenin ‘oops! puparl rena) care peta elu cu aston din reins, ‘Acre ale sot one ees Ie umn, cl asi vedere cept i socara ir a pute prec detail calre (nei cae rence fren copa dine) Tn ps ig sepeerzes tor epi in lemons slew proces decree cop, Care de iain Uhiporteminaca) A dace a sehers acs vse nature, karen gobo Ink esa erofaiml).deenerescnj cores erate). pe apes soln (perken, nett creer a cop, Crotenl (in mercot ‘Heo exe provamina A Exe de taind iperiainss) etrant ‘ue de cele lec, esceamne ll ugh able, tn portoeie = li (eaetenodermle). Fomacatape Init sehderes seu re a {ntanerejuncledermatie snoae dean heat conic tie ~ Vitamin D, ergocletera) 9, (clear) sunt vise sn abc ce aber esta ele stile area an ose ‘Anum oneal in preveles ator dene. De mena itanina ', poste sinatiza tn pe (produce eodogent) sub acjunes azar a ‘ete ds special lars rode camps dcr Hiprtaincee D proven acpi cata ae ar le ad oseoporaa ft oseomalc ipervtamineeD produc ipeacemi, clic ens pls padi Se Farmacterpi eat prof ttre bl egal a opi exaoperot, osteoma hipoparsim, THC xan. ~ Vitamins Eocofera) ee viumin ert ae ral wae exes aot penta fst mca pecum pee anna Carn de tain poste dace a sderes fri vr sponta, tub earomosclre neni. rmactrapt da distro screw demote 1 ‘Vitamin F (arm in an grag pons: acd nal soli arahidnic) ae rain ots normal tepuneti, Cra duc le sparfa ecamel gs anor bur toe count. Farmacia = VitaminaK(aafochinon) et vitamina anibemorgic ise sla- ex prtrmbine (Setral Il eagle), procnvetin (tral VID ‘tetra Start Prover (fitorl )- Fair ro produce engin ct ‘i Kin colo, to acianen Sore baeriene prof (n pei cerca (Gaps [ct (Soni [omer ined Vermin [Reinet [Bae repradind 74.4, VITAMINELE LPOSOLUBILE sig trena hn et 03 fms, [Ege [1s asp amine o- [iain [cae | 8" #08 Janie” [mena [et Sedo Nains me oa gt eer era py: yt ie alte acts Vina iodo [Pepa oi Raa tit seating —] Bees crset ac a nw laste Nami cnn ne Janae [estes lanes (Wai, — [Adee ro [zvoc [veennen, —[Actpamene [lam (crete ani iat Ing pertain, [Vie Hing eC frnaminn, — [aaa inne [inisb, — [cumrbiind —[Sedomenys oa [insin—Adeuaic , [Sedans cceuaete et Ivmiea® fast” ‘Yom mtg Nene ose) Notre lnm Indep: cee; leas tone al pel sie |Cee Ine esi ins ol apo) Caren de trina Kt enous (pineal resind floater clon ces inter) produce baa emer [Hel Lal paren sinroame dealer nicer ober, ‘Seurmiind fenmene hema: pins plier metre, nema rap dig, singer posterior Farmactrapie Inet: indroame Iemrapice pi deft de proton notin supradorareaaticaplan- ‘Wor eae ous Remora « NN pla defect de potombin ft peo= 174.2, VITAMINELE RIDROSOLUBILE ~ Vitamin 8, (Gaming, nears) are ra in buna funonr a moc user eros central i perfec. Cara duce a polineuropae, vig nitpmus burl deen arian, canapatie Farmaco nda: polnaropat ner ves: bipertolan; aber art elem roi ‘Vitamin B, botany, Ictofavns) cote a trofcisen os ‘nal pl in speci a mcouelac, Crea podoce derma seborich, Infamsi bole Get) ib (ls) prcum f newopate pre Furnaces Inde: stonate; lose; coe ae demo; erate enjuncvite; annie micocet pein deft de Guttion- educa; me Iemogobinenie coogetals Vitamine (tami PP notin lac exe vans ante Japon in pees NU el selene cade pln fr oa), ‘Arran bola pron glares TA fancioazen aoa wSNC. (Gira deer snore, cle! abdominal de, drat seas ‘x eriem i fictene; but newopabie cu agape, confi chiar dle ‘amacsenpie dai ancl sein el mocoslr hiperipers ‘otesopatlperiei talure calor bola deirdre = VitumioaB, (ocd penton) role mtabolaes gsi ro fete pel enor mactes spr; merinerandametl as. Crt Setenin sennheiser nd teen unr mice hertapoel tn meaner LDL alee ere te fet aerogen tn te noel. Cara prodice nearopate perfec ‘secs somal gos, enemle hpocomd mlroctnr; I a6 acal Sig mic determin cool hmodsinare Prmacoterpie da: ‘wee ett lp acolo stl dps nem oa de adie ‘es pene; medicament de prot a bls wat cu ola; conras idol dear aang mi. ‘iba 74, Diet prods farmacetce conning vitamine yformee ‘stp pea — perce — eres ama ————— es [nn etree SE, Se oe ao oe at caret =, ae re eee er aoe = Sat ae hearer =r ener Se eaten 5 ae Ser aR are * re % =r = ena = a ea =n : 2 a re tes ice Soa er er gna ae aes hae aan no ce eins tt esc ameter Ascot re) : cas eae eee isreneat ‘CRD SLARCEAN, VLADIMIR MANTA DUALESCD ~ Vitamin biting area neice el nr enn rir nom l gem cleseclemie ftom muscular Caer Seer mai ipotnie exc dermait scborich pe ib go ‘senorese, great virsitn, hpereltrolenie Vitamin B, (ai fl) parte seza prota ahematopo- leak Carns profuceanemie melo, plot, chit, drs arma ‘temple Indi: oeale medal Birmer nea acrecze le ‘opel: poet- pees and ‘Vitamins, (@ancobleming lp cle rl testa nage: ‘ism nna pin combines cn ctor iniae rod de aco ut (Din acest mati in sop tees se amin nan net an “Aeron hematopoie s bun fancioares sistema eros Cares Se ‘ermind apemie meplblesicl (anemia peacoat Harmer) plierepee as Hunter amacrine polinearopati; nee; neg de lugenen; ane meld Biermer epaithconic cos beptey age = Vitamins B acid pangumie) inevine tn procs meal ete scion. Cvefa poate rode bua catincerervonsefendorne ~ Vitamine€ (acd ascorbic) est varia antscrbute (sorb ex ‘oa aare setualment extrem de rar). Vitamin eee rndamentl fe SHinelectn, met rests sin, net ere asa are eet {elon Corona snde apc I eft inane; poops eid ‘ator desta fenorene eneragi:pingivrai pt bua, beme- ‘oame rbpeiosle;anemie; hots rer, Farmaterse Inde nf bacteria su virce (prolate dbo espe ae ‘ml exenle; oteoporea; cntlescnt; mtene;sindoume emerge ‘in vascuopt; intel cu substan mebemolobineate (ein. {Ea eid: prade de fort poi em nlc Vitamin Puts ese vain permet capi Considers enitenjascetora Cerf deterini henaagh cap. Farmatape I esarag epee tne, get, eae varices hemoptll e- ori . = Cariina (evocarnitina; Mico’ este 0 wines, conser 1 factor tar ie” (genie viamiolr. Ar ln xiaessioe 99 Caes In carlin determin upatczcaren clipe» unr fst ‘aruba mosclare eptce,precum to cardlomlopte eae ment defend in ret mica gins peor neafsen cardiac ron kine crease pene, starede sei estat Adminirze a, “Tubchl 78 ifr sociale laminar er ae ee aereon —ren ete pore lee eee ais . bres fags (ast etapa ae Sede ae ca om oo i ah en psn 8,8,.95 + ep No csi» macs 2 [pvt tind 10 vanin CaP, [Stas fee an + Jet cu hy hn CaM 7.5, SUBSTANTE MINERALE [A 12] Roll subtnor mine tn opps ete mul, de Sind inp ‘able bse fanctont a orgenlor apart, he ac nel et ee. rein ani forte mi Sern de ant pest aera de ir mile reprint amet, care conse foul iolgl de prc lo "lees ioe cre portale ete det game api ae: rieldemacrosenente (al flr soda, pa don Hemeatle zeae Sl ror neces net do orl migeamelor nach ol lrg lec sunt microcerment sa Olgodemente (fe eae ne, cba ot, Bt, ‘mange, len). it st ~ gebert de cae patois - nearer lente sunt nab (fel al sparta dies), sant Insite (slept ca vrei deo cule ol tc) in aeetcana ete neces sopientre spr deiner po ante medlmentose us 75.1. MACROELEMENTE MINERALE 4 Calel (Ce ten cement chimie cuca metic end went ear poeple erga “ro paler), rnd ~ sb form defor ale -in componii {ert oor qn comport dens, yl fanciona pia componeat st onc dn pam (Cx), meni in limi nema etabltues neuromasees olin coagulres slgeh, cecaien inca fern i sd eta a ‘ous extrem de mich NU ext tbc de couple In pose) find desemnat de wail autor dep factor TV al oul ~tcjne antnfastordesesilant ‘Deft de eu produce exeopord, steomalc, pede dente, spss char rie de wane contrat maser aus) ‘ease cleerpe: ai pare; tenn eigen pamnode scjoant oan: eneopred; pet console dep fats oc ‘ona eral eel serge de dere spo. ‘Tubal 76. Contin icles fre srs ublzate tn erapetih Smtr | roan | laden [nel de [ease [an ‘ome ‘ommet [Gewdecn Po. issu | 475m ea Si Baby 32501 [eit ss Sime Ismael (Sees ci i ‘ies 2s [cuenta er Smug | L2asenet eee io ssn Sasa Preprate medicaments de clea (ngs tn ere soc) i ponies frac "i ~ Adativa Clem + Vib, plcljcuplber nib in ap, 00 {nnd te 1000 mg eae (= 50) 200 cele = 5) ~ Calla 250, comprinste mst conn erbnat ei. Galcataate comprinats. = Gace eflervercen instant, granule sfervercnte contd alsa o- sit celeron sori ~ Calcum Sandor forte, compat cervscente cotinine ghus- at decaen satonat deca CALC, compete eevee conned calc, ai ascorbic, celery vitanion 86. ~ Corea sla rl pet conn or de cli = Glaconat de el, ole entra adanitates i [de evs ales Len eosece ete fore deren, th i de bed sci pies unl Supra (ego fee). ~ Siop decal, conjinnd pe Bocwe Slit 1Smg canine (C3). ‘Magner (Mf element chine euewacter matali re urmitoarieo- bat ne in cooper stu os in cantina mick ect call) pin components plasates(g”) meta n ine orale exciabaea toromusctles fc ansaid; eter pests testa! 9 contrat eka bia. “dale erp cu pepe coninnd mage: cx canlve pete; gesmolie; a de anes smreln eee pala ‘reparate medicamentonsecu mags: = Gatamag +B, spre cominind lutamoglaonst de apni p= sadn ~ Giuconoacat decal magnesia, fein im. (po be); Magne 6 rer 9 ole ure ne aap) oid lett de mages pido ~ Magner compyinatecu eat de goer ~ Magnevit,comprinate mat ogi coat de magnet pe oxnt Sod (nti, Na} te un clement imi carter mt sind sumone oa te pric cao (8) inch extracel (Ueda teri + ‘ssa LCR) ab form de ore rod, vn li presune exis purple iba acid baie Tale tera cu pepe cate conn wd we de dedidratsre ca prin perder dress ue ens, ists, ani po. ze): pentu rate cust] cimioeripiet cu de mari de estates ‘nse coronene ‘Pros cre contin sol ~ Solera de sod 09% (nda dene er folog") so- titeotons pang flacoane petra PEV 9 dizer otter ed ‘nent net ~ Sole lorur de soda 1 sola pero nfs pent et ~ Sole aru de soda 55%: soup mol lpeston, ia acon pet ~ Sale Ringer png comjntd In sna clr d sedi + clorutde pot crate ac penta FEV. Soe Ringer act: png coninnd cle componentee soi Ringer tin encentai frie) + Tact de so, pete PV. Sole de icrbomat de sodiu 4% solu ml, hiperton, a ‘oe per admistraretn PEV incr de clon. 1 Sarr penta rebidatre oral (OS) Pots (ala, H)s cement chinic ea cars neti are umole sol te pnp ein (Sra Sind din acest punt de vedere ~ ‘atagnis al sod; parle clr cdo: fae n mecaniraal contac! masclre, intervie in activates cotati aca Celio dep sol, “nd leap cu pepartcre conn pots: ere med po- tesa prin re vat (gstroentre tne alent ble ~ Gat sendiinisrest nual pt rear les; eed idroecttice Pin nec de ane cre pode eine potas (raemid); cre de rieteaiepelagisunl aml aac; intone glen ite ie goin. Prada cre coi potas Mopar compra spat de pote apart demagpen Sarefirssodi, pulbere ori. * Sole rar de potas 7.45% sue mol herp, acon esr administrate sir penta rehidatare ral ol eyation ss = ORS) Aen: oko te iperaos NU weal dita pe lt cl ect nisl lpertont NU teal ero ch tri Ven, uma (ph dare In $65 miter produce nuns ete le pettl venos. #cloral (C2, pincp anion dn rnin an toate mde ke subform decors de el glare rol rege preuitosmot; ite dat de din sual gases parcp lamblia idee celia spel in xpi. "armacoterpie: ace indi cul soln Produc fermacetc care conn dor tse sll crs de soda, sola de clr de pots, ug Ringe sre pentru rebar mm ‘Fosfor P) ese un denen cu arc cine neta, tnd ei tear ro: nn compotion, combat xcs form eft tee In in compan nalenprotincar rin pene sn acl nc, on ‘ind wel atenaiters infra geet, pis campus sal adenine (ATP cet acum et ener els din roe bohimie cts nt apa in on tele marae, contin estore tampon de mene aclu aco bs eat acd de Neforist mononl dN). “nat ale peputlrcu fos: stn; ommalcens ren Sle su lec prion console «Factor ii dedepei it ‘eeaihomotonein copie Praparateconindnd for (ia ete soli sant rode tone, perm) Centrum junior, copeinate mastic contining 13 vain cl, rom, cup fi fir fo agai, angen, molbden, lnm ne. ™ Hlvit Prost conpeeate lat cornind 12 vitamin cco ru fer se, magne mangas. “Gerold conintnd proc ld Bena, ort de po- asa et desea "ciaseit cape connind erat de pesng 12 vitamin cco eer, for agen manga pane ~ Vita, ape contd pte de mat glasng, ple, sios a 12 vaio, er for eoprs mngs, odo, 7.5. OLIGOELEMENTE (MICROELEMENTE MINERALE) Floral (Fest un clement metal din rps halogen Pei Inted In comport dentine seat detrs oni a prose de ostogenea. Farmacirpie prepare ea Ou ut nda proes cro en- tare: in steoperea peur in ce senda din case regi ct ester in east msec onl Produ frmaceutis conn ior "Fluor Vigantletes,comprinteconjnind clear! + Suorurt eso (top rofl). “Teidiat conprnnte maticble comjntnd Lgltmin mane: Sosa, rt de ela gacont deel ~ Osi" dines parr conning fcr desi, ‘CN bance vuapran srs MDIALESCU (ada (cement ema din rapa logos arrow func th cate un component de btn struct orm tien toda a (19) teundairoina (14, rex): la catei de od ervine poodle epne unde sll ape sunt ‘sear in od sce afcine spar eb forma de gut ended. "Prodase cofindd inds o"Saretodat ain comers Nodar de pots compen, Peal (Fe) clement ete deeb important pests ors: ine cau coipenet de bark insur hemeloine| in ete de sr se produce memihipocrom eric); hin comport mioglbin| in meh senor men car. Prodasfrmaceatie coninand er > Pept ca Bet (Terapia mari- 1 neapd = MEDICATIA SANGELUL ‘Capel (Ca) lament eae: rel ior in bematopciee; “in tn comps unor eine, ‘Preperatecnpinindexpras =Total mb conintnd pcos rox giana de cpe aconst de manga. ~ Vitama caps (eso meres) = Addame”N.sltie perfil i cave cone numezase ligne mene ub formd der. t Zina Zn, eest mete: iu craters enanemll@ muaaare seats “nei acne ipoghamiatss insane: “tore mune rps nd mal ett de ude ba viet eaclant, 5 ‘Preparatec ie = Zin 10th erect Addame!" Nose periaabl ix caigedamene Scena (5) clement eu eect pene: srescune antonanisstvnd cnc! lnenaime din grupa glutton peo- soln m ell ene ins ld i peasant ‘ului zaharat;, ss a ee rer lr alge acre. ‘represen crc cle) = Vitamax*, : ~ Met Nl perinbit 1-6. PRODUSE PENTRU NUTRITIA CLINICA ENTERALA ai ae te eos ae ae ae patos icp rs natin ve spa nap oe Som em cas apn ae ee end ae utr eat Aah eal ep pepe ek i eas em rpc apn ae are Be ‘cocanpete be ll os one opr ee oa “te lage pon a kala pl ne furnizeass (9.2 kcal/gram) gi glucide (4,1 kealigram); 7 Shemini Se seb mn “Stpsenent cop nn cess “tebe che AL i Pac pa ‘staccato “ose oo devel pt dc Sr nar ee ar pate ing Se isd ep se ape ocrwon ges pls prin sblue meee ape ‘See cept inet htcpests cme ew nt re Bes tegen isnt sa coe ‘apie Gxe copia eda nese ee ‘el as eis mt hp espe orwell aan es ‘Sey am pt dsl re St tin nc ea ane nec poept fein pre epee ot dane ey tin in ne pn te ease ps “tener le ESS omental (mi “rte pub ep nm pl na ‘iN Manan, van ATA MINAS ~ Ravare Pas ui coin se ata peprst xaom de vane (ashe 60 “Pods, cl x produ hid ca aro de vane, sit copllor Sale: Peabin” Original Dink (te nrmoesorc: 100k = {20 i) reson” Energy Drink (os lar calorie dat: 150 ell a=aokiad; ~ Feeubi" Energy Fibre Dik conn re org eal petra mle tana testa, "rose cal cx per pena peparat supe oll cu som de ‘nile rnc fils sr depletes in cate eit ifr rent snl dae cn ements peut ‘ts de Pr’ con eon at l= Ss la gree 8 {Tipe 36 pl onisind ws po lp Onege 20d eeopeten al > ‘ethan; gle 2038 grea cla amine 14,0, EX, By, By ot acd putt le elaine: ‘otha fot a dates omen vo. ‘Soli penta sdaiisare expe oad maou: retin’ Orginal (enormocloi);Preubia”Origial ire (con neve de origin esta ~ Breubl” Energy (co lbure alorien iat: 150 kal = 630 a. 17. SOLUTIL $I EMULSM PENTRU NUTRITIA (ALIMEN- ‘TATIA) PARENTERALA ENDOVENOASK (8 05 BA] [Nuttin parenterali endovenoasi este 0 metod prin care:macro- mi coourimentce un adminis fr Je sl ema I nl ‘See cleol ns poste ozs care nee splinntre lineal ‘rin perfintendovenose it dec rat parenteral endovene ol, ocr lava (ecient) ‘bu poate punt nine pe cle oral tote ntrimense waiter pin peruse [Us cunoscatom de sat cntemporanfind int tre decom Fe gi dp un cient scarcer (AVG ore ri rein. ‘lptidn oes, fot nt nv al deca nae preterit lovecat “nate parenteral endovenast paral, care completes aliments rl “eles tpl pareterleendovenaase so ~ dap interven operator ample in pei pe ahdomen tb digs Seat pancreas Taeienn pl waomatn in tare coms prong: = esata fs 1 ence efile dare pean its, encflie, meni, side culate cereale ae fea cere wales dec ~ si de densi epee: ~ evict ae npn aliments pec og ‘nape connie perintel endovenns pret ‘Orie uti renter endevenoe tal bul sigue sport ne ‘esa tonsn componente: 4 Apa cree caer n func de viet, gett corporal perder elcid pe ieee inrodueren sor pro (tnge pass ‘medkcemenione) eventual apr: pra deed pe ale ola. Conte ep print prin PEV bul emake cs oa stl ys ae oe de 30 geo leer pi erfoi 4 Susan nate zat sb frm de slide aminoactt (a ‘are enansmal, pin proce metab i stem prc sega pi me i protein prope ~"Aminomis sla prin de amiss pag Beamer = Aminoplasmal” 51 10% , soli perusal de aac, = Aminoplasial Hepa 10%" nd a aera hepances ~ minster KE sole de sminoas ia dou rain: fr ela = Aminstrl Hepa 89" nde nei in ae hepsi, ~ Aminostr KE Nephi di in nace els cay Amine er 1 cea cade ~ Aminoven" infant 10 (pets opi); ~ Inf 40% 100%, # Glcidle sun amiitat ub form de slut de lacoeh 10% 20%, 39% Taco fn aes administer de gocoe se lnypane asain cu donde ning cx cians (sin el 4 Lipdele se dmisreas ab forms de em fate fn, pil de Une rodent LS ec inectara I #subanflrulaneee esote mera, prodichd o emboli sat oval Bole pete ‘PV sun at bri, nt particule ore ne oho peat ae ANU AARCEAN, VLADIMIR MANTA MERIC = sonra Aun conn opal empl denice wn ula petra endorenss sa nap oben px PEV conn esi gh flan 102% emp PV ce dene ~ Liporena” 1% 20% ems peu PEV co eo ositetot hi a Ormearet emi pence PV amin el eps opr cue acl ven RIOTS ene pena PE cul deo ine el de analog de pone #Hlecoliiseadmlaisuens in fence de near ni de event see perder = pa Sola declrus de sod 0.9% (fxg) salud rast soda 585% (eee alart cthiperon cae tebe dat inatede sdnimeae, {ig Rigi cane abe Pooh prune poco endo feos ea tts cement 1 ducan. ©" amparner cnn ne pts > Conon ois Seo oats pect opt Soper compris ee ‘Srono perce spate ppincipinwe pra Pon pt de {Srumkare pert rch ct aoe ess oceania sea ‘rn isopes atr 3opera ces pert su oe maascorocie 5, Solu de clorar de potasia 745% solu molar hipertn ace sare ase adit, = Sola Rings, conjnind le un ra: orc de so 8 orn de cali 9 corde potsin 03g ~ SoluiaRingeactat conjinin ots: arr deseo 6, dart seca gclorurt de pots 03 glace soda 3.20.9 Exit formule combite is eae ens tote componenseotcence une mute parent endorencnse al ac mule esr schon, ‘ale pur de eri i cle pei fear poten pre ~ Kabire®Kabiven" Peripheral: png tieamere confide come stent uperior slue d glucos 11 in conpartinetl es soe tec amstes de aminoai eel ainoce nese ceca tren comartinent mas denied O png! de land on ‘orl de 100 kel. 78. ANTIOXIDANTI $I SUPLIMENTE ALIMENTARE, Antioidan sot ssbsanje care neuter ber rena ' rma proceso table din eta. Aces ral sn cleo re ons esr para toe bl graven rlgne eft locals, ‘esto pulmonare, tbr ale SNC, define lester! nar de "spruce. I xtegoriaanondanfr itt vain, utente miserly ine, Ces are parte dau cee exe prvi slime te aden pei uch mere cae ep legume aspera mowers so, eves bool cri ul, adt ver, tara prepa pe as dp, el de pete Atoidanfi se gsc # mb frm de repartee serviuminde 4, C9iE; utp Omeps 3 diese soplinenesimenine, Suplimentealimeatare = Visi cone xsi, plcat. Complex de nana ations, amine arg sobstane nivale fre generative tomate tect de lung dura ex mate pte de iunortinle spel, tn "pel peroande cu images bl consumptive cope ~ Uleidesomen Ome cuvitamna cpr Uli de pete coi ‘sil gg plinesturat ca moles mar tip anne acid emp, {acne (20, Sn) acl docraennem (C2600) Aceqin eel stnterogen repnd nell calesteaa din las (ed LDL caesar ace part In proce de seogenest gcse nll HDL cleo ‘ee stinerogn, sad tell trl plasma, rant spe ‘eon iinet tendna erect de congue stage agit oooh closes er netvos na (CRN MAREN, EADIE SATA MINAS = Coensima Q 10, case. Ete econ, poten sem arta i jut cries cond in Leng, redace pertesianes rer Inet semal iar pin eters imanoglobue! (ig), fortran “neecenplgl, inrele proces de bei ‘Dement ci aca courig ela i pyle rs micro ade lojtncaren dt opane de anima lt desi, arbi dar te activa a pocrres termi aimenteoe 130 8. MEDICATIA SANGELUI DDEFINITH st EXPLICATIL Erirpaet » produia de hema n midurs hematopoietic (nude Pi 6 fas een eagle = caberecrom emai emote een ge samara i i ot gh ace poropenoy Aine thm (Digjone) homo apt fara ea pe het wont Ida pte meee hemos ene toe pice nere cha pe out ml Anse = ‘Vitamina K, (Fitomenadion) este vitaraina antihemoragics, | participnd Insaum poten feu oops poor (aor "ia eng et nit bree mle bl se po es (ede de rsa pri ‘rl eh cba es at nena ‘ulm carne i nccmearl = onbetop Aminte ponents rcapeen ede emslete). Ringe ioenocmpltien Pe ctr al cong. a ptosis in Roe Adin revit ~ Globulna antibemofics A te orl VI al oagul Se reat lout in uni interstioale nda: beri Aq el aed bow yoo Wilerand Se presi su ost forme pin ce perfec ~cpulbere flies in momenta adits pacar pe nears mec x Eee erate Ps mana; Kogente Byers, fb forma de lo cong: econcentat de labia atibeoflch A, ‘cata separa In constr 5s deeghesi rp nape cls nama In ‘omental adminis nellsiads- a espera corps Ode Gna st NU mal post recongeat: su sector a se arc ~ Factor Xa coapulel (ernin immenine se peso ob for lina se daar tn momeatl perfec email tp B ~ Eplagogalfaactvt (Nove Seven) canine facta VIC congue Cxp.29 ~EFECTE [ALE MEDICAMENTELOR IN CURSUL SARCINI $1 ALAPTARIT]: bol 3 ‘adore hemorapiee ter gaeduodes. natriuresis penta prepare sole inet, te pin wa are non, [iv acelg inal conan ren here ca aenpcuarchl ‘Antal efor cama ete tumioa K natal (tomeaadon) In ate senior medial. P oath drat waste ao gla (dan ete tel) treba montreal tinal dé protombink (Si natal INR ionatonl normale rae) Perr eizare benef teapetie da psu ears siden hemorgice, IN rb men- tit vlna 2-4 Cores pee sent ive pent eric deme Tar impane el pun lyre dons de scout sua chi aspends- fen tetamensa Sederes INR ob obliga mes dal liner ‘eclfine benef rape nine 18323, Chase pase [B 01 AB] Heparin son animes ca acne aprorombln 9 anrom inch npldicnd formas erboplatnl apnea ober le donee nun lternaonle (a) Inde tromboleite, tromboze ‘nll ater namie forme de afew; n cirri adv ‘Slash (ena ok te hearing, unde int dele) Rec od 8 “Thea 81. Comparten encoun oe (camry beparne een ole(ee Borie (Gieceaiaie [Oa Pomel iz mec acral ces [Lene 7040 rs Tt [Becton nei? Sale is ore inadmiies loos ‘ove eadeiatres [se eprint ev at nce re aba eis [Tip promo NR APT impale cst dena ee eect pas ated ini tink a oe (Pomendion vs Fiamt pou con (eet ip deci ae epee pul) wea omen henoragle pio supradnae Pin acs eet, dept event Pelco cau up eaten fst de pba neespernentt ne (ic use relist omontoceecovei astra dala facie de ‘zal isto de prot. Antidon heparin a eae de suprdorre ‘te protamina. Conran: bl sndoune hemor (womboctope ‘semi: ligne eavort: rom tern anes cereal be smorgi cereralis ITA sever leer astoduodenl. Administrator ptr metres APT inp enon pal -Heporine standard (nefationate) ‘Au cfec ecg antitrombotc ~ Hepa fle 5 00 11 la 225 00 wl pnta sini teu I ner de elt #8 oe sata PEV contin, dpa dare slic (Poco 5 su nse filo. Heparine cx mas molecular med aces prop de heperne, fal anticoagulant el entrombote snt ccs = Daltparng (agin), ering prep pete dire Ta de can produc ties ‘cu Masczas, veapim anea MDIALESCH ~ Raoxaparink (Clean), scone cs neti srg press ple pentru tminerae cS prefers amiisrreatn eaten reece bona anes rofl pena prevents tromboze [tee yene profande,a ele! almonar late wor nerve opetso- I cag cunt: srbote Youre ponds, engin pectoral ai Utne formed fret ica Adminisrare de dbo pea act 1208 * Nadeoparind (Fasparne’)seinghpeeunplte penta injec 8 Adina ong ain 24 Jeo ™ Revipcid (Clara), dacoune ca sla jean! peu pe pente injec nda pola oro a mblilar hise [Gate peveze congue in car modal aceclaelextracorpore- Se yomenl obovate Tate attener media sjecares xe = pate ca mall mo eal ede ae de pfu sebetanat al peeled Stein fn reqinde tral (ane). 183.3. ALTEANTITRONBOTICE ~ Sulodesid Vere Doc) ete georgian cx ile fe ntizombote,fbrinli, hplipeml,hpolrnogeeriant.Adminstt {il ima Lv teste conta spot pe cle ral uit: tom ‘ne stra von acento cre cere. Cantril 9 ‘Sndroume hemoraie| geri eee arcing, {4.44 EVZINE PNRINOLITICE $1 ROMBOLITICE 801 AD) i pene medamene cine prin ares sobre cheng dj faa St ate Gar aa plc etn rds pin, ee repcnan (qe) frat dik patra 5 (Step) se pein a fra repute onde oc; enbaleplnoata tembo- 1 vnunl prof och rer peri prin above su bebe. Conrail hemor ecient scleral: ee stood pean postopera poser: TA. tela (Aue) et oglcprdtein acvaou a lamlnogesit cular nd nes et ion de mocarsembode pe {bom Se pete per oli peta pep seis peep (PAD (Rap) ee onal attra! pesnogenah, cefrmtnde In plain. Acts nee ice de ge (Gombus eb, data ea ie neti aor: ‘slmoce, 10 ‘84, PRODUSE §I DERIVATE DE SANGE [B 05 AN] 441, PRODUSE SANGVINELABILE (P31) scan tn tn att coche tmemacatareneseae reat esi cicero Sarge mart Tag aumaennp mori ma eerie crete cance Sectoral ean tae ‘in hemoragii masive externe sau interne. a a pyar ste: Sith Seman eae tia gt Svisciiciert eta eye ip peerapel gc eta * eerste cana = Se palin eeg nt ports eee Lienert cha pclae gm onadagi ees ie ae ceccumne Senna ome Sc eneetenee testa =e none Gia emai ecoamoetr aa Sue Te grumtemas td ses betes eee reat paaerrerernrar yoo ed coer ncuatacn ment marmn a ca ener esate rt laeeenementimt cates Smemier Incident postiransfecionale medate i tentacle mada): frson; ers puss up urearint su erp lrg dea See rs ‘BANE, VLADIMIR SANTA MINALESCO lrg; ware de ane; dae rack, abdominal sa lombare res ‘Soursdlapness there enomene deem plmonar ct hipotssune ‘revlon cgpanresemoplablaure ete hemol; pai ‘esinges Compt postrangicionsle tre eb Inlacl de adc ace latte view IVs fete cy virus hepati B wu Cs neta ‘irc (CMV), 1442, PRODUSE SANGVINE STABILE ~ Pas wea allt In acoane dest. iar $0 pe aor, etc mat su tines: pesto "abun mand (Fama aun) 3% 10% sa 20% acs de stl capi str de lpopoteners sce bey ast roe he {les inom nef ul poe operator sn tama, Concentrate factor VIL in facane mil es. nici: emote tip Asbona von Willebrand. * REIBA (actright nites bps activ) plbere flats la ‘eet tn ali ip care x cae no apt nb on (pian Vere amen eine acs) Concent de factor Xara ip B factor Vita ecombinan (Nevo Seen n fanned tilde este tip Ap Bn spel Ir exe unde aparinhbr nto ‘fcr VI) bal von Wilebrand ‘85, SOLUTI MACROMOLECULARE SUBSTITUENTE DE PLASMA (PLASMA EXPANDER*) [B05 AA] ‘An nical nyc mati cl din pancreas pei oe ardogen oe esti oe aaa congue nase diet {cit gin spel in goo hpovlenie in returares yam plasms (tenet ol eran ee neces simiasrare de sage tl dost provolone li nacrmolclre ee NU inaport de element ‘ell sngyne Peprat: Dextran 4, fi perfil 10% confine macromolecule de dextran muse 000 Se pein in ovr: noi glacork 3 ‘Sins clorarl de N09% (er log). 7 Dentren 7, slap 6 conte dean cu mas mole ust 7000 a dou vasa: nal glocor sin sll dorr.de 09%. 1 = gt emacs prac ac i hema ge etek ye redone) eu. = sk idm mt 00's ec en ‘al lida Pre comer Haw seh. pote Newt sae per Sh, ehcp verte Te ie mao nr a ot deans rt noe en et acces po teat Senet i cc ene oe perv ocala 9, MEDICATIA APARATULUI CARDIOVASCULAR DDEFINITH SLEXPLICATTE lr arovenear (0-0) = dace contrat vere fi de otra, sf! ol sucesunes normal (teri wath de ‘Sol tener) ma ext cel doo pr ale inland activate ‘Spur linependent denials enealat mpeinst de null “Stovenclr Asch Tamara deve independent in x de loc &-V ‘ssa lens et nodal = ab decentracimin) det even rl ondast de nodal sual Ke ac (sinus = cx. 60-70 de ‘otaciin. “Compl QRS p ECG =un rp trl unde itu, vail pe ese _cecroctloga cae repei fra deplete {nt emespunind cu nsp stl! ena Dart acai = 06-010 reinde Thera -Q pe BCG = sograms = prune de trae dectocado- gai acrid Pepe P-Q Cnespuraod eel wile [mpull decoodecee a dee dela sea venlese).Darts ermal = 012-020 eecnde fay Thtreal Q.F pe 8CO = porianes ping din vnclgras (ace ep al incode le semen) = prunes de trate decvoarogac ‘Sls din comple de wade QS + segmental ST + und (crespunsing ‘Epnish qi mpoatil vemzielare del ssl ventricular), Darata oral = 24-042 secunde i opel afi» pte bile = potential crc a une xa crim feed ensane dete te zoe eat pote Mtnepopeg lea ner substan} ptetll ropgs)-aloares edie = 1050 Reni pot = paras erpi cisanteasettor cle dino sul ertemsog stele noi eo Seake maf rics, el), eer vet ulate caracerel oll qi subst, Ete prod de ‘itor sndeamentog, tt oa erg Me | Shira WPW (Wolf. Prkinson-Whit)» bra de es adie da caus exe din outer (coment) aos! sl splint de fut od sel Ken) peed inca deta pce ale BCG. Insc carats pr defo: fle msc ese aoc te ine ey send ml an soci Acne Sete nce xt is etl ol (actos oun entero cara erode corel fll peta conc eprops Recon ‘eet fr ee ean ori pode te an ‘leur nodal soem fc amu gh dep se era ven nates respecte) an ee Pa ‘9.1. CARDIOTONICE DIGITALICE (GLICOZIZI CARDIOTONICH (C01 A) tn pret din gms cndva ap pont ipl, cn mal mae pate us alleen peactea metal cent Sma foe dn preptle ang == = sate ate a rs Feelin == 7 ‘5 elated a ana Sa aoe open Decl inet eat propaga rset stp ld oe ‘in rd van dere pesca ee tree {Rina sa Att mings neue creo pe mac (Adve comnaing create ton ene IN MARCEA, VIADIU AANTA ALEC Tab 9 Tarmacotoiolge Reale adverse ale goin! sunt important, dn cei tala cu digas efstetah sb supevegere medi 6 ‘cul 1, Uncle prope posloga gone Permet [admit peros — [Admits Ped dea Gin [eo 5ninte eet al a Tae Da er Sale Deaton cores val acctrapeic lll 08-2 nil 1A asSame) Nw ene ss 3ginl ps4 ei ‘Dade saws ingle ia ls rptwain de |istmgatretaual [ae asiaghsce ces Seer) Saco [Peaster sia 125959 mgt e0- ea maar nana wt [Ls Gere 10 Sant dooce wc atic decane | 258-754 dn onl si yo eons eats (Cer) [steric su pt stain nce cee drs Sor [cher 1 mia, Sn ih ceca 0 28% ln as ul nw dens aerate, Sas pot enini oe sor da uct ear 1c mies pl del x montertaes 300,P reak ‘Be rt de nee rae pth nee, a fle ewan modi ogee EC 7 > Cap.32— INTOXICATIE ACUTE. coe 9.2. STIMULENTE CARDIACE: AGENTT ADRENERGICI ‘STDOPAMINERGICE Acute medcamentseonens arora eeptair ccepunto a mi card dar gasipra unr vector st In ale organ, Et lr ste Se st mlae de intesticre neontactlr mica cee fone inte musolrdsanenor gain ~ Adrenalin (epinetina) scion agi (= efot det): aspera arene oan fet mica tl ex ‘ocondacor init, product alae cers tal carats ssp copa adrenals eed etre increase, podacind rere tn ately tupac deer st In miscra ee arerieoe ‘in ceulsa pulmonar, dtemintnd rece tenia pulmo, ~ supa receptor, ~ seer stn mascara ted npc ‘eon mets onl rodilnd ltr roses (ect ti cd ‘min stn de stn boo nt de pai bronbodisttotlr atu). Tnajde drone in eaniarencarlocistre (adore. et ‘unt: nae cu ans loa dinistae sc); yo analacte ‘Senne sees adn nt dat a repeat). Ie admit {in pesincie de eras ae. Barmetepraferenelirain ole ‘otal mgf ° Noadreslna cfc strato sens arcuate mal ‘och nds clage vane Adiseare dap area SC 3 = Dopuminn fe cert cen apet aginit al receptor a- adencpe In doe mid ete coronal arenaditator peat sie cers pele; i doa ed este cudosolet in dae mai {ie vetoconscr al rela veneor Indes: ye edge, foc Ua Ima, yor sete acl aie ce, tab de vm en, HA. ‘Adina in PRY, ap ure re in 5a SG Dobetamina (Dabutrer) ete ager agonist leapt sdeaege produced hide peers tv rie. nde eri nc mica yo cdg, espe Rent ede cle (1 Dopamine Adminstareia PE dap dare pela Sau 865% ~"pilefrine (Thome?) scfonesh snopa rempanlor 8 a drones determined cee tll cra pa eosin ater “nda hipetnsane til eau oul one, postopera Be pwotone ois, Admire orl Sc, Ln. abla sa in PEN tip dare prea in SG Mildodrinn(Guton) seinen agonist sopra expo a, ade gi dn arte peril product © cere 2 ten ater. ede hipotnstane real uefa esate, potaperso, pop ‘im, dn coveleeen Contrndiaic HTA, pee e prosta, per- ‘olds, Rear adverse: dare precordle,ebur de im eda, eene ‘ath Sun. Administra peron iy. oy 9:3 MEDICAMENTE ANTIARITMICE [C1 8) “Tre dein cian aml de origin snail: ial de contrac poreyte dn sina sav akin ee dies de normals antl prooerte de aps une oar ectoplce (> heeetpe act nora sts) de produces = stimuli de contac mlocra Din acen- {enoore ae prs exacts trl cle vsteelr, tera ta ‘ln at eer arn uprevenicalar ode xa als ~ siti pin bart de ondocte a stir de concise ui oe snot stoenrcle ‘Medicametl antares apa cli lone princas- ‘ee mebeear. Inurl ptrunderes i cll) de ode Na Cx pode Cp 5~ MEDICATIA SISTEMULUI NERVOS VEGETATIV. we Farmacotrpi Date proproolui: ahlear ¢ rt spraven tecalre;enasmoleatritegvetieune; HAs cardomopnte pero havact eee Rrpance in tli Flt migrend ‘armesnpiemisgs. Conran Badr notin cardiac; Loc srventiar:hipetenson pln stm bron ogee, ler prtrodsodenal:eceml peice Terracotta adore: xe; hpeensiane ati bed dies brnhospasn; agave sun caine, Antic dn casa Ih set init pte xi Bai pote sic Dine ac, amfodarna re cle as me dea aad lef ‘etre ute 9 dae srs exsiele sre venice pre postin mica Anarticle din dara TV sntnhitoae le aa clic Al se {nce verapamil ving urmitoae ida ubicre protic ae rset sindrom WW alert; ter Sap ‘Si etastole: ITA ajoad nee caroniopaelipervotcbtracns ‘Farmacoplenilpe, Contrada. ropa natin eart- sed oc eogen adie hipoteniune seri ae stowentrcla "Farmaco Reel aver: ge; cnspae; bade! hpo- ‘eosue ar: ste ard; stenie; eel somogle. Din alte grup de medicament, umitonee a propre nti: Digoxin cod isa cre ete pe deo pate batman Ip pati, ede al pute const romotep eg In, con- tral rea advene > Cardston diptale glen cron) [co.ay ~ Adenosna etic sia nora n PSY unde ae ndeatia sme Dine eacile adver amin: press roshespeet ipe; br ‘cede ‘tenia aitenlr media ‘Plated seams de mamerontele reac adverse woe ce wt, de sistas medical anritaice se fc, einer alent laa. ‘ine i, mama in plea sub sopeavegherea medal nul personal uexpren fcn monitor mantle din, pull! ECG. Se 10 1 in seams de contra preenie rent in prospect cae Isjec medcarental (prospecile bale ei tale! eva wrt ‘sre urerosselr incompatible aceon mediaset [> Cap 30 [REACTH ADVERSE (EPECTE SECUNDARE) ALE MEDICAMENTELOR ‘p31 ~ INTERACTIUN SLINCOMPATIBILTTAT! MEDICAMENTOASE] sews opel media aan reacilaradvere importante Osce nadie Inch trapeatis wef cuss pel “Tubeal 92, Mediamentele ntaritmice (casares dps Vanghan-Williams) (C01) [Gsssat- oci ame. lDemmisier [iaeseamiiee [Gldecce jer |e er ie [cisiat |caitsatic [Dare anion [ok ‘ut |Congeimne)| rosa we pegs a> lout ana pe peng ne womincpne FE ig |Posmamii|Ponagt [Gran eal soo [mterendoc, [pect ‘roses mer: Barrer. i neste mic |v ite ceric |p (igeteian anne iwi [aaa (SSE eed [i Joiners eo erst eet capa [Ga ema ab ich sens sty) widen wo aa [ssc | Rea he Jsecrocitipe [pac [ints rambo em res i, [Reh lamete ma ras met aptecot Pepa Ren ab oe one pat ‘ymerom” jn (cont, folie et ea 151 Continue bell 92 9.4, VASODILATATOARE CORONARIENE [C01 D] eee cs ga ee oceiees acer Ind major mata qa en a ol oc ecm ace cnn cris mg sl dee fates lates ec ‘abs, venice C01 Sma" SSS SS sper soe a os anaes fins apa scene ss _— er [See cate rca, ee ay our cece es ieee howe fen Ae se fms See ae feo [ote eee. fee ge el ay es ee a a ee epee: [teams [Sete | a ete (most [oars sna es es —— ae Sea om lepine. [Eocesees ee a eae te re +t [Rowen four naut oma ame aa oe cent ican (ene rence a. poe heat feb oma Bt h lene ee ear peg feels sist ong [angina ston to ftir ‘ fee fe [mae (cee [asin eee ne er coms rs ie fated oe — == token prema — fesse ens ato feet |i [aec ir t peas == eo ae! ca foe ees eee eae is ~ Neogicerin se elas coronaria rapid dur drs 18 (exceptndfomele eu ier petang- a ve poate admis sla ful Compe gpa rl pera (comprinat) fn PEY et a forma dese tandem (lastre care sigur oabaoelet de dart ‘ssabeane. ~ Pentel tetrarat(Ntropecto), pep tot pe bak deve ‘expt o psoas dete ma ng pI ntalren ct ag ‘Sutne rela. Adasietae eal compra), ~ Iesrbid dsita (Dinter) are propre semitone nope ‘ee penn su form decompeimste,eapele ca eberte peungt spray ora ~ Lzterbid mononitat (Monotone dart de acne ang ‘ah de dink Administra rl (opel cuelberre pela compe smaeca eee peng) ot deal pind vasodintntorl coronarine Tae 9.3. “blu, Vasdlatatoarecorneren administrate substan in ‘op poate tliat in inferetal mioearde Neopia esc pin engi noel ed ea [open crea meh et ae ‘Sib tame» 24 sain sce renal er tn vert meee aa “Deal 95 -Heablocante indicate ia eardiopati chemi cronic yin lpertnsanes arterials pears (C07 fae a oe [Oe an met eget oo ep [emp t) ast — [bates sea Sse ste rae Ss eset et — x Sat aa sont aan se lamba copaoa et te emit coy eect Demat se nr fie) Pt — eT ae ar a lie) at — Te Gp “Tube 96 thir al esimel de conver angiotensine! (ACE) Indl! in cardigan acheris cron ipertensaes eal primar (CO A Feces Sars eee Deke ‘Densmiri comercial ‘Cheer ar eee i le eee Siete ae [emer Borns ndotnan dpe rps Oa =. ee ese a edad teenie apie [Secarmnigcentmtstt prt leet cet [SSeirtenent a ts le a oe = es ie eet tn rte eee — eer corte ses ——— oor emanate — cea ia es =. ees ie Farmaco fete scar al tact bred (ns pin cle care au acne betagoist); insula aac congest roshorpeam (nai putin spent eli), dco gutta Seder ern laan a hn opevaren abel naar a ical Inpatss. 9.5, MEDICATIA ANTIHIPERTENSIVA [C02] ‘lorie tensa ater (TA) a un alt interpetent contre be- "TWell 97 tterprtare estat arte (TA) cadres hipertensual areca (HLA) la peroan adele Taped | TAs ant) | TAdn inn “a ‘a ‘mis Theptmt Pig 10 tn cp.) Medamente in cee grup ~ Captopril; rasp (Enap); opel (etc 95 Antagni f anglotnsnl IL Bloch eet npotesine (> Fp 10tnep 8h. Alt ae ino 19 = nr) vn Bie mans a eet $m aman Pte nn Eee == Bre ee a ee om san =a 17, ttn Ss is es rae eae ont feta i ee Peer Ee wires —— el d- n t e a Se ee = Seni | npn natn SS ee na eae tet som er 9.5.8, Diuretice ca eect antihipertensiv. Actoneaai prin sckderes volemiei ates itt cemtt etme feof ‘= Hidroclorotiszid (Nefrix"). = ‘ite ‘Farosemid, dure deans cu actne rapid i eft sluetic tens, (ell =e cama ——— een pe == ee ey a eee | wnt Pein det > Tbe 98,999.10. aise |Caea espe cacti Ee Siento ha ca npr ee an Se f= [Aion din Reserpine “Te rmepind >| TA = Same ae {Gren + io eee te lesen Soma ae sear common ee ime a ee ia ear eS = aes er pir mn |e Comp lence See cone ieee i fo 18 1 _Coneamane whetal 3.6. “‘Tabelul 9.9. Antagonipti ai canalelor de calcin (blocante selective) Fat — [aga ena RT acai Ta (Co ements oe Paar ee aaa sree | ten coe eee — Ee ae rae [ea Fa ia Peat |e em mt oe sri ste \Sostea etme (cmp Sen) iia Alinta RE; Ditinrefopaake | Hipetersane arterials — ™ see pcre a a aan ae] ne | at ere ee feoyetinin) [rea as ease Some haar ia cma —— men ab leon |e (nt step pina [incase ponte {ear sre aa ica Sm ae a aa ae — aa pe — Poca ae fscminn [oi (fief ar lem acpi [Seton oy atacat nea teagan cea seer ca tcepapar se ene 7 ear a ape zeae - ce a “Mie 10 Nedletnden tet pec ince a lige led proce de HA naa (repre sarin ir pe frog chine) esas Fen oem ere eager | ra \Sbeeeecg [taecrte feat lear a Pa sce Se Nea ean aa siiettnean | [ets octane omer a scree, [marae ter lee) * ee ice com re a aE pea sie ccc fate et — are one ing Ee (a ™ \tegey [ emai Bs