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Pulmonology, cardiology
ICD-10
R23.0
ICD-9-CM
782.5
DiseasesDB
17332
eMedicine
med/3002
Patient UK
Cyanosis
MeSH
D003490
[edit on Wikidata]
Cyanosis is the appearance of a blue or purple coloration of the skin or mucous
membranes due to the tissues near the skin surface having low oxygen saturation.
Based on Lundsgaard and Van Slyke's work, [1] it is classically described as occurring
if 5.0 g/dL of deoxyhemoglobin or greater is present.[2] This was based on an
"estimate" of capillary saturation based on a mean of arterial versus peripheral
venous blood gas measurements. [3] Since estimation of hypoxia is usually now
based either on arterial blood gas measurement or pulse oximetry, this is probably
an overestimate, with evidence that levels of 2.0 g/dL of deoxyhemoglobin may
reliably produce cyanosis.[4] Since, however, the presence of cyanosis is dependent
upon there being an absolute quantity of deoxyhemoglobin, the bluish color is more
readily apparent in those with high hemoglobin counts than it is with those
with anemia. Also the bluer color is more difficult to detect on deeply pigmented
skin. When signs of cyanosis first appear, such as on the lips or fingers, intervention
should be made within 35 minutes because a severe hypoxia or severe circulatory
failure may have induced the cyanosis.
The name cyanosis literally means "the blue disease" or "the blue condition". It is
derived from the color cyan, which comes from kyans, the Greek word for "blue".[5]
Contents
[hide]
1Definition
2Causes
o
2.1Central cyanosis
2.2Peripheral cyanosis
2.3Differential cyanosis
3Approach to diagnosis
4See also
5References
Definition[edit]
Intracranial hemorrhage
2. Respiratory system:
Pneumonia
Bronchiolitis
Pulmonary hypertension
Pulmonary embolism
Hypoventilation
3. Cardiovascular diseases:
Congenital heart disease (e.g. Tetralogy of Fallot, right to left shunts in heart
or great vessels)
Heart failure
Myocardial infarction
4. Blood:
Polycythaemia
5. Others:
Hypothermia
Peripheral cyanosis[edit]
Peripheral cyanosis is the blue tint in fingers or extremities, due to inadequate
circulation. The blood reaching the extremities is not oxygen rich and when viewed
through the skin a combination of factors can lead to the appearance of a blue
color. All factors contributing to central cyanosis can also cause peripheral
symptoms to appear, however peripheral cyanosis can be observed in the absence
of heart or lung failures. Small blood vessels may be restricted and can be treated
by increasing the normal oxygenation level of the blood.
Peripheral cyanosis may be due to the following causes:
Cold exposure
Differential cyanosis[edit]
Differential cyanosis is the bluish coloration of the lower but not the upper extremity
and the head. This is seen in patients with a patent ductus arteriosus. Patients with
a large ductus develop progressive pulmonary vascular disease, and pressure
overload of the right ventricle occurs. As soon as pulmonary pressure exceeds aortic
pressure, shunt reversal (right-to-left shunt) occurs. The upper extremity remains
pink because the brachiocephalic trunk, left common carotid trunk and the left
subclavian trunk is given off proximal to the PDA.
Approach to diagnosis[edit]
This article contains instructions, advice, or how-to content. The
purpose of Wikipedia is to present facts, not to train. Please help improve
this article either by rewriting the how-to content or by moving it
See also[edit]
Acrocyanosis
Raynaud's phenomenon
Blue Fugates
References[edit]
1. Jump up^ Lundsgaard C, Van Slyke DD. Cyanosis. Medicine. 2(1):1-76.
2. Jump up^ Mini Oxford Handbook of Clinical Medicine (7th ed.). p. 56.
3. Jump up^ Cyanosis. Lundsgaard C, Van SD, Abbott ME. Cyanosis. Can
Med Assoc J 1923 Aug;13(8):601-4.
Medical si