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Pharmacoepidemiology
Yusi Anggriani
Pengalaman:
Dosen Fakultas Farmasi Universitas Pancasila (2004- sekarang)
Komite Nasional Evaluator Obat Baru Badan Pengawasan Obat dan Makanan (
2001-Sekarang)
Tim Nasional Percepatan Penanggulangan Kemiskinan Sekretariat Wakil Presiden,
Pokja Kesehatan, Bidang Obat (2014-Sekarang)
Komite Nasional Penilai Obat Jadi BPOM RI (2002- sekarang)
Komite Nasional Informatorium Obat Nasional Indonesia BPOM (2011-sekarang)
Tim penyusun Pedoman Farmakoekonomi Kementerian Kesehatan RI (2011)
Dosen Manajemen penggunaan obat, MM Kebijakan Obat UGM (2003-2004)
Apoteker pengelola Apotek di Yogya (2000-2004)
Staff peneliti Pusat Studi dan Kebijakan Obat UGM (2001-2003)
Objectives
Define pharmacoepidemiology
Understand the relationship of
pharmacoepidemiology to other disciplines
Understand types of Pharmacoepidemiology
studies
Understand the importance and clinical
relevancy of pharmacoepidemiology
Pharmacoepidemiology in Practice
1. The basics idea of pharmacoepidemiology is: to
measure the source, diffusion, use, and effects
of drugs in a population
2. To determined the frequency and distributions
of drug used outcomes in that population
Pharmacoepidemiology in Practice
The World Health Organization focuses it
pharmacoepidemiological efforts on ensuring :
The quality, safety. efficacy of drugs
Drugs used in specific populations
Pharmacoepidemiology in Practice
The organizations of pharmacoepidemiological
studies are performed to:
1. Describe current patters of drug used in specific
populations.
2. Determined changed in drug used over time
3. Measure the effect of information, education,
promotional activities, media accounts, and prices
of drug use
4. Detect inappropriate drug use and associated
problems
5. Estimate drug needs in terms of disease pattern
6. Plan the selection, supply, and distribution of drugs
Descriptive epidemiology
Describes disease and/or exposure and may
consist of calculating rates, e.g., incidence and
prevalence.
Such descriptive studies do not use control
groups and can only generate hypotheses, not
test them.
Studies of drug utilization would generally
fall under descriptive studies.
Analytic epidemiology
Observational studies ( such as case-control and
cohort studies)
Experimental studies (such as randomized clinical
trials)
The analytic studies compare an exposed group
with a control group and are usually designed
as hypothesis testing studies.
A (local
B (local)
C (local)
D (multinational)
E (multinational)
20
15
10
5
24
22
.5
21
19
.5
18
16
.5
15
13
.5
12
10
.5
7.5
4.5
1.
5
Time (hours)
Suryawati, 1992
18/2
2
20
Tempat
Tahun
% peresepan
AB
2005
59,6
2005
53,1
2007
53,9
2008
50,9
2005
58,4
2005
25,2