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BY CO-CHEMICAL CHARACTERISTICS
C. S. Jawale and L. B. Dama1
*Zoology Department, HPT Arts & RYK Science College, Nashik-422005
1Zoology Department, D. B. F. Dayanand College of Arts and Science, Solapur 413002
Email: csjawale@hotmail.com
ABSTRACT
Tinctures of Sp haeranthus indicus were prepared by using 30 to 100 percent v/v ethyl alcohol by
m aceration process for 10, 20 and 30 days. M axim um yield of total solid content having pH 6.10
with specific gravity 0.99 and brown colour was recorded on 30th day of maceration at concentration
of 30 percent v/v alcohol. Such effective tincture can be prepared and utilize for preparation of
a n tise p tic o in tm en t and o th er fo rm u la tio n .
KEY W O RD S: Com positae, Co-chem ical characterisation, Sphaera nthus indicus, Tincture.
INTRODUCTION
Sphaeranthus indicus (Linn) is a member of
fam ily Com positae, com m only known as
Ghorakhmundi is abundantly found in southern part
of India especially in damp and in cultivated fields
after harvest. It also found in the Himalayas up to
an altitude of 5000 feet from Kumaon to Sikkim
(Gogate 2000). It is extensively used in Ayurvedic
m edicine as tonic, cooling, alternative,
antihelmintic, and in the treatment of styptic and
gastric disorders. The pest prepared from roots and
the aerial part is useful in skin diseases. It is also
useful in the treatm ent of cough, in glandular
swelling, urethral discharges, jaundice, indigestion,
scabies and in remedy of piles and nerves depression
(Chopra et al., 1986; Kirtikar 1987). Recently
a n tib acterial activity of benzene extract of
Sphaeranthus indicus was reported by Mahajan et
al., (1998) and suggested that it is due to 7 - hydroxy
flru llan oied
(Naqvi et al., 1985). An
im m unostim ulant activity of sesquiterpene
glycoside, Speranthanolide has been reported from
the flower of Sphaeranthus indicus by Shekhani et
al., (1990). Hence, taking into consideration the
topical application of Sphaeranthus indicus in
various bacterial and skin diseases, present
investigation was undertaken to form ulate an
effective tincture with different co-chem ical
characteristics viz, total yield of solid, change in
pH, specific gravity, and colour with effective period
required for preparation of tincture.
Strength (% v/v)
Colour of the tincture
30.0
Brown
40.0
yellowish brown
50.0
yellowish brown
60.0
Greenish brown
70.0
yellowish green
Table 2: pH of different tincture at various duration of maceration.
Strength (% v/v)
30.00
40.00
50.00
60.00
70.00
80.00
90.00
100.00
pH Duration of Maceration
10 days
20 days
30 days
5.80
6.07
6.08
6.20
6.16
6.16
6.04
5.53
6.02
6.19
6.13
6.25
6.19
6.18
6.07
5.71
6.10
6.20
6.23
6.26
6.20
6.22
6.10
5.91