DMC COLLEGE FOUNDATION

Sta. Filomena, Dipolog City

ALLIED MEDICAL SCIENCES DEPARTMENT
First Semester, SY 2016 2017
Higher Education Department
Semi-Final Examination
RMT

Cytogenetics
Ruel C. Maddawin,

Name:____________________________________________Section:_________Date: 11/17/2016 Score:____/

I.

Multiple Choices: Write the letter of the BEST answer before each number. NO ERASURES.
1.

A disease that is present at birth and it is NOT always genetically determined.

a. Congenital
c. Extra-uterine infection
b. Environmental
d. None of the choices
2. Traditionally, diseases can be
a. Genetically determined
c. Both A and B
b. Environmentally determined
d. None of the choices
3. A group of genetic disorders with multifactorial inheritance pattern
a. Monogenic
c. Polygenic
b. Heterozygous
d. Homozygous
4. A disease that is caused by tissue accumulation of excessive amounts of Uric acid crystals
a. Myocardial infarction
c. Arthritis
b. SCID
d. Gout
5. It results to the precipitation of uric acid crystals in patients with chronic arthritis.
a. Tophi
c. Lymphoma
b. Leukemia
d. Peyers patches
6. The following are the 3 clinical presentation of gout, EXCEPT
a. Asymptomatic uricemia
c. Ankylosis
b. Acute arthritis
d. Acute renal failure
7. This is a colltective term that is used for diseases that resulted from a mutation of one gene
a. Monogenic disorder
c. X- linked disorder
b. Polygenic disorder
d. All of the choices
8. A genetic disorder where both homozygotes and heterozygotes are affected
a. Autosomal dominant
c. X - linked
b. Autosomal recessive
d. All of the choices
9. A term used for a person that carry defective genes
a. Homozygote
c. Carrier
b. Casualty
d. Recipient
10. A genetic disorder that resulted from the production an obnormal protein fibrillin.
a. DMD
c. Marfan syndrome
b. Rheumatic fever
d. Acute renal failure

11. How many pairs of chromosomes does a diploid cell have?

a. 46
c. 23
b. 22
d. None of the choices
12. Identify the complete pair of male sex chromosomes.
a. XX
c. XXY
b. XY
d. None of the choices
13. How many chromosomes does a haploid cell possess?
a. 23
c. 22
b. 46
d. 21
14. What organelle houses the DNA in eukaryotes?
a. Mitochondria
c. Ribosome
b. Nucleus
d. It is free moving in the cytoplasm
15. The mating or crossing between two individuals that have different characteristics.
a. Mutation
c. Condensation
b. Hybridization
d. Procreation
16. In hybridization of species, this generation composes of offsprings with uniform phenotype.
a. 1st generation
c. 3rd generation
nd
b. 2 Generation
d. both A and B
17. A term used for an individual with two identical alleles.
a. Homozygous
c. Null
b. Heterozygous
d. Genome
18. This term refers to the outward appearance of an individual.
a. Phenotype
c. Null
b. Genotype
d. Homozygous
19. An inheritance pattern where there is an equal expression of a gene on an individual
a. Dominant

c. Amorph

b. Recessive

d. Co dominance

20. These are unit of inheritance on a chromosome

a. Alleles

c. Loci

b. Genes

d. Telomere

21. A genetic defect of collagen fibrils that resemble Marfans Syndrome

a. Cystic fibrosis
c. Ehlers-Danlos Syndrome
b. Celiac disease
d. None of the choices
22. A type of autosomal genetic disorder where only homozygotes are affected.

a. Dominant

c. Amorph

b. Recessive

d. Co dominance

23. Which of the following organs are affected by Cystic fibrosis?

a. Lungs

c. Gall bladder

b. Pancreas

d. all of the choices

24. A disorder that is characterized by the absence of the enzyme phenylalanine hydroxylase
a. Phenylketonuria

c. Galactosemia

b. Maple syrup disease

d. Huntingtons disease

25. A disorder that is characterized by a deficiency of any one of the enzymes involved in degradation
or synthesis
a. Glycogenoses

c. Celiac disease

b. PKU

II.

d. Duchenne Muscular Dystrophy

Thoroughly discuss the pathophysiology of the following genetic disorders.

1. Severe Combined Immunodeficiency Disorder

2. Duchenne Muscular Dystrophy
3. Cystic Fibrosis
4. Celiac Disease