Propylene Carbonate at Dow Chemicals

Product Safety Assessment
BETACARE 200 Hand Cleaner

Product Safety Assessment documents are available at www.dow.com/productsafety/finder/.
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Names
Product Overview
Manufacture of Product
Product Description
Product Uses
Exposure Potential
Health Information
Environmental Information
Physical Hazard Information
Regulatory Information
Additional Information
References
Names
CAS No. 108-32-7

Propylene carbonate
1,3-Dioxolan-2-one, 4-methylCarbonic acid, cyclic propylene ether
BETACARE 200 hand cleaner

1,2-Propanediol carbonate
2-Oxo-4-methyl-1,3-dioxolane
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Product Overview
BETACARE 200 hand cleaner is a colorless liquid with a characteristic odor. The active
1
ingredient is propylene carbonate, which is present at less than 10%. For further details, see
Product Description.
This product is distributed within the automotive aftermarket industry in Europe as a handcleaning solution. For further details, see Product Uses.
BETACARE 200 hand cleaner is distributed to automotive aftermarket industry professionals
only. Consumer exposure is unlikely. For further details, see Exposure Potential.
Eye contact may cause slight temporary irritation. Brief skin contact is practically nonirritating.
Prolonged skin contact is unlikely to result in irritation or absorption of harmful amounts. At
room temperature, inhalation exposure is minimal due to low volatility; a single exposure is
2,3
unlikely to be hazardous. For further details, see Health Information.
Propylene carbonate, the active ingredient in BETACARE 200 hand cleaner, is readily
biodegradable, unlikely to accumulate in the food chain (low bioconcentration potential), and
4,5
is practically non-toxic to fish and aquatic organisms. For further details, see Environmental
Information.
BETACARE 200 hand cleaner is stable under recommended storage and use conditions, but
can decompose at elevated temperatures. Avoid contact with acids, bases, oxidizers, and
6
reducing agents. For further details, see Physical Hazard Information.
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Manufacture of Product7
Production BETACARE 200 hand cleaner is manufactured exclusively in Europe.

Trademark of The Dow Chemical Company (Dow) or an affiliated company of Dow
Created: June 27, 2011
The Dow Chemical Company
Page 1 of 6
Product Safety Assessment: BETACARE 200 Hand Cleaner
Process Propylene carbonate, the active ingredient in BETACARE 200 hand cleaner, is
prepared by reacting propylene oxide with carbon dioxide as shown below.
CH3
H2C CH
O
Propylene
oxide
O
CO2
CH3
O
Carbon
dioxide
Propylene
carbonate
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Product Description8
BETACARE 200 hand cleaner is a colorless liquid with a characteristic odor. It is an aqueous
solution containing less than 10% propylene carbonate, with small amounts of fillers and other
cleaners and additives.
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Product Uses
BETACARE 200 hand cleaner is distributed in small tubes within the automotive aftermarket
industry in Europe as a hand-cleaning solution.
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Exposure Potential9,10,11
BETACARE 200 hand cleaner is distributed only to automotive aftermarket industry
professionals. Consumer exposure is unlikely. Based on the uses for this product, the public
could be exposed through:
Workplace exposure Exposure can occur either in facilities that manufacture or use
BETACARE 200 hand cleaner. The intended use of the product is to clean hands so
exposure will occur when the product is applied to hands . See Health Information.
Consumer exposure to BETACARE 200 hand cleaner This product is not distributed to
the general public, so consumer exposure is unlikely. See Health Information.
Environmental releases Small quantities may be released into the environment if this
product is discarded. Propylene carbonate is very soluble in water, and when introduced, will
have a tendency to remain in water. Because the compound is readily biodegradable, it will
be removed from water and soil environments, including sewage treatment plants. In the
event of a spill, the focus is on containing the spill to prevent contamination of soil and
surface or ground water. Small spills can be absorbed with sand. See Environmental, Health,
and Physical Hazard Information.
Large release Industrial spills or releases are infrequent and generally contained. If a large
spill does occur, the material should be captured, collected, and reprocessed or disposed of
according to applicable governmental requirements. See Environmental, Health, and Physical
Hazard Information.
In case of fire Deny any unnecessary entry into the area and consider the use of
unmanned hose holders. Use water spray or fog, carbon-dioxide or dry-chemical
extinguishers, or foam to fight the fire. Use of a direct water stream or foam may cause
frothing. Firefighters should wear positive-pressure, self-contained breathing apparatus
(SCBA) and protective firefighting clothing. Follow emergency procedures carefully. See
Environmental, Health, and Physical Hazard Information.
For more information, see the relevant Safety Data Sheet.
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Page 2 of 6
Health Information12,13,14
Eye contact Contact may cause slight temporary eye irritation.
Skin contact Brief contact is practically nonirritating. Prolonged contact is unlikely to result in
irritation or absorption of harmful amounts.
Inhalation At room temperature, exposure to vapor is minimal due to low volatility. With good
ventilation, a single exposure is unlikely to be hazardous.
Ingestion Low toxicity if ingested in small amounts. Small amounts swallowed incidental to
normal handling operations are unlikely to cause injury; however swallowing larger amounts may
cause injury.
Repeated exposure Repeated exposure has been reported to affect the lungs of laboratory
animals.
Other Animal studies have demonstrated that the active ingredient is not toxic to the fetus and
did not cause birth defects. If handled in accordance with proper industrial procedures, exposure
should not pose a carcinogenic risk. Cellulose, an inert ingredient in the hand cleaner, has been
shown to interfere with fertility and reproduction.
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Environmental Information15,16,17
Propylene carbonate, the active ingredient in BETACARE 200 hand cleaner, has low volatility,
and may slowly evaporate from products containing it. The substance is very soluble in water,
and when introduced, will have the tendency to remain in water. It has minimal tendency to bind
to soil or sediment.
Propylene carbonate is unlikely to persist in the environment. The substance is readily
biodegradable, which suggests the chemical will be removed from water and soil environments,
including biological wastewater treatment plants.
Propylene carbonate is not likely to accumulate in the food chain (bioconcentration potential is
low) and is practically non-toxic to fish and other aquatic organisms on an acute basis.
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Physical Hazard Information18

BETACARE 200 hand cleaner is stable under recommended storage and use conditions.
Elevated temperatures can cause this product to decompose. Avoid contact with acids, bases,
oxidizers and reducing agents.
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Page 3 of 6
Regulatory Information
Regulations may exist that govern the manufacture, sale, transportation, use, and/or disposal of
BETACARE 200 hand cleaner. These regulations may vary by city, state, country, or
geographic region. Additional information may be found by consulting the relevant Safety Data
Sheet or Contact Us.
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Additional Information
Safety Data Sheet (www.dow.com/webapps/msds/msdssearch.aspx)

Contact Us (www.dowautomotive.com/contact/)
2-Oxo-4-methyl-1,3-dioxolane, Biodegradation and Bioconcentration of Existing Chemical
Substances under the Chemical Substances Control Law, National Institute of Technology
and Evaluation, Japan
(http://www.safe.nite.go.jp/data/hazkizon/pk_e_kizon_disp.html?k_no=1152)
Propylene Carbonate, European Chemical Substances Information System(ESIS), Institute
for Health and Consumer Protection, European Commission Joint Research Centre
(http://ecb.jrc.ec.europa.eu/esis/clp-ghs/index.php?INDEXNO=607-194-00-1)
Propylene Carbonate, CAS No. 108-32-7, TOXNET Hazardous Substance Data Bank,
National Library of Medicine, U.S. National Institute of Health (http://toxnet.nlm.nih.gov/cgibin/sis/search/f?./temp/~4NOPaK:1)
Propylene Carbonate (CASRN 108-32-7), Initial Risk-Based Prioritization of High
Production Volume (HPV) Chemicals, U.S. Environmental Protection Agency Risk-Based
Prioritization Document, April 2009 (http://www.epa.gov/chemrtk/hpvis/rbp/108-327_Propylene%20Carbonate_Web_April%202009.pdf)
Propylene Carbonate, CAS No. 108-32-7, eChem Portal, Organization for Economic Cooperation and Development (OECD)
(http://www.echemportal.org/echemportal/substancesearch/substancesearchresult.action;jse
ssionid=9AEE61DFA32F78F01E03B83EE894C65E?queryTicket=SUBQ7xa&view=grouped&
pageID=)
For more business information about BETACARE 200 hand cleaner, visit the Dow European
Automotive Aftermarket web site at
www.dowautomotive.com/capabilities/industry/aftermarket/products/eu/index.htm.
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References
1
BETACARE 200 [Hand Cleaner] Safety Data Sheet, The Dow Chemical Company,
December 2, 2010, pages 1 and 3.
BETACARE 200 [Hand Cleaner] Safety Data Sheet, The Dow Chemical Company, December
2, 2010, page 4.
Propylene Carbonate, CAS No. 108-32-7, Human Health Effects section, TOXNET Hazardous
Substance Data Bank, National Library of Medicine, U.S. National Institute of Health, accessed
December 2010.
2, 2010, page 5.
Propylene Carbonate (CASRN 108-32-7), Initial Risk-Based Prioritization of High Production
Volume (HPV) Chemicals, U.S. Environmental Protection Agency Risk-Based Prioritization
Document, April 2009, pages 47.
2, 2010, page 4.
Page 4 of 6
Propylene Carbonate, CAS No. 108-32-7, Manufacturing/Use Information section, TOXNET

Hazardous Substance Data Bank, National Library of Medicine, U.S. National Institute of Health,
accessed December 2010.
8
BETACARE 200 [Hand Cleaner] Safety Data Sheet, The Dow Chemical Company,
December 2, 2010, pages 1 and 3.
9
2, 2010, pages 23.
10
Document, April 2009, page 3.
11
Propylene Carbonate, CAS No. 108-32-7, Human Health Effects and Chemical Safety &
Handling sections, TOXNET Hazardous Substance Data Bank, National Library of Medicine,
U.S. National Institute of Health, accessed December 2010.
12
2, 2010, page 4.
13
14
Propylene Carbonate, CAS No. 108-32-7, Human Health Effects section, TOXNET
15
2, 2010, page 5.
16
17
Propylene Carbonate, CAS No. 108-32-7, Environmental Fate & Exposure section, TOXNET
18
2, 2010, page 4.
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Page 5 of 6
NOTICES:
As part of its 2015 Sustainability Goals, Dow has committed to make publicly available safety
assessments for its products globally. This product safety assessment is intended to give general
information about the chemical (or categories of chemicals) addressed. It is not intended to
provide an in-depth discussion of health and safety information. Additional information is available
through the relevant Safety Data Sheet, which should be consulted before use of the chemical.
This product safety assessment does not replace required communication documents such as
the Safety Data Sheet.
The information herein is supplied upon the condition that the persons receiving same will make
their own determination as to its suitability for their purposes prior to use. In no event will Dow be
responsible for damages of any nature whatsoever resulting from the use of or reliance upon the
information herein or the product to which that information refers.
Nothing contained herein is to be construed as a recommendation to use any product, process,
equipment or formulation in conflict with any patent, and Dow makes no representation or
warranty, express or implied, that the use thereof will not infringe any patent.
NO REPRESENTATIONS OR WARRANTIES, EITHER EXPRESS OR IMPLIED, OF
MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE OR OF ANY OTHER
NATURE ARE MADE HEREUNDER WITH RESPECT TO INFORMATION OR THE PRODUCT
TO WHICH INFORMATION REFERS.
Dow makes no commitment to update or correct any information that appears on the Internet or
on its World-Wide Web server. The information contained in this document is supplemental to the
Internet Disclaimer, www.dow.com/homepage/term.asp
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Form No. 233-00844-MM-0611
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Propylene Carbonate at Dow Chemicals

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Product Safety Assessment

BETACARE 200 Hand Cleaner

CAS No. 108-32-7

BETACARE 200 hand cleaner

Production BETACARE 200 hand cleaner is manufactured exclusively in Europe.

Created: June 27, 2011

The Dow Chemical Company

Product Safety Assessment: BETACARE 200 Hand Cleaner

Trademark of The Dow Chemical Company (Dow) or an affiliated company of Dow

Created: June 27, 2011

The Dow Chemical Company

Product Safety Assessment: BETACARE 200 Hand Cleaner

Physical Hazard Information18

Trademark of The Dow Chemical Company (Dow) or an affiliated company of Dow

Created: June 27, 2011

The Dow Chemical Company

Product Safety Assessment: BETACARE 200 Hand Cleaner

Safety Data Sheet (www.dow.com/webapps/msds/msdssearch.aspx)

Created: June 27, 2011

The Dow Chemical Company

Product Safety Assessment: BETACARE 200 Hand Cleaner

Propylene Carbonate, CAS No. 108-32-7, Manufacturing/Use Information section, TOXNET

Trademark of The Dow Chemical Company (Dow) or an affiliated company of Dow

Created: June 27, 2011

The Dow Chemical Company

Product Safety Assessment: BETACARE 200 Hand Cleaner

Trademark of The Dow Chemical Company (Dow) or an affiliated company of Dow

Created: June 27, 2011

The Dow Chemical Company

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