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Biochemistry Mnemonics
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Biochemistry Mnemonics
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Biochemistry Mnemonics
BIOCHEMISTRY
MNEMONICS
Essential Amino Acids
PriVaTe TIM HALL
Phe, Val, Thr, Trp, Ile, Met, His, Arg, Leu, Lys
Urea Cycle
Ordinarily, Careless Crappers, Are Also Frivolous About Urination.
Ornithine, Carbamoyl, Citrulline, Arginosuccinate, Aspartate, Fumarate,
Arginine, Urea.
Cell division
Prophase, metaphase, anaphase, telophase.
"People Meet And Talk."
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tonsils":
ABCD:
Anderson's=Branching enzyme.
Cori's=Debranching enzyme.
Otherwise, can't really distinguish clinically.
Nitric oxide: amino acid precursor
When the dentist works on your teeth, you say,
"AAArg! (Arginine)" before he administers Nitric
Oxide (NO) to take the pain away.
Other players necessary for NO synthesis: NO
synthase, Ca++, NADPH.
Pompe's disease: type "Police = Po + lys":
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RAISE K+:
RTA type 4
Aldosterone or mineralocorticord deficiency
Iatrogenic: NH4Cl, HCl
"Stenosis": obstructive uropathy
Early uremia
With hypokalemia:
ReDUCE K+:
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Malate
Folate deficiency: causes A
FOLIC DROP:
Alcoholism
Folic acid antagonists
Oral contraceptives
Low dietary intake
Infection with Giardia
Celiac sprue
Dilatin
Relative folate deficiency
Old
Pregnant
Mitochondrial DNA (mt DNA) properties
"mt DNA".
mt stands for: Maternal Transfer Mutates
Tremendously (high mutation rate)
Vitamins: which are fat soluble
"The FAT cat is in the ADEK (attic)":
Fat soluble vitamins are A,D,E,K.
Enzyme kinetics: competitive vs. noncompetitive inhibition
With Kompetitive inhibition: Km increases; no
change in Vmax. With Non-kompetitive inhibition:
No change in Km; Vmax decreases.
Glycogen storage: names of types I through
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Biochemistry Mnemonics
VI
"Viagra Pills Cause A Major Hardon":
Von Gierke's
Pompe's
Cori's
Anderson's
McArdle's
Her's
Sickle cell disease pathophysiology
SICKle cell disease is due to a Substitution of the
SICKsth amino acid of the B chain.
Glucagon function
"Mr. Gluca has Gone to the cAMP to bring out
some Glucose":
Glucagon elevates glucose by cAMP mechanism.
Van den Bergh reaction (Jaundice test)
"Indirect reacting bilirubin = Unconjugated
bilirubin":
Both start with vowels, so they go together:
Indirect & Unconjugated.
Hemoglobin binding curve: causes of shift to right
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HUG":
"Crazy Glue":
Strongest bonds are between Cytosine and
Guanine, strong like Crazy Glue (3 H-bonds),
whereas the A=T only have 2 H-bonds. This is
relevant to DNA replication, as the weaker A=T
will be the site where RNA primer makes the initial
break.
Dicarboxylic acids (alpha, omega) C2 through
C10: common names
"Oh My, Such Good Apple Pie, Sweet As Sugar!":
Oxalic Malonic Succinic Glutaric Adipic Pimelic
Suberic Azelaic Sebacic
Infantile Beriberi symptoms
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Fructose-1,6-diP
Dihydroxyacetone-P
Glyceraldehyde-P
1,3-Biphosphoglycerate
3-Phosphoglycerate
2-Phosphoglycerate (to)
Phosphoenolpyruvate [PEP] Pyruvate 'Did', 'By'
and 'Pies' tell you the first part of those three: di-,
bi-, and py-.
'PrEPare' tells location of PEP in the process.
Fabry's disease
FABRY'S:
Foam cells found in glomeruli and tubules/ Febrile
episodes
Alpha galactosidase A deficiency/ Angiokeratomas
Burning pain in extremities/ BUN increased in
serum/ Boys
Renal failure
YX genotype (male, X linked recessive)
Sphingolipidoses
B vitamin names
"The Rhythm Nearly Proved Contagious":
In increasing order: Thiamine (B1) Riboflavin
(B2) Niacin (B3) Pyridoxine (B6) Cobalamin (B12)
Electron transport chain: Rotenone's site of
action
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"Golgi
Distributes A SPAM":
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The HILL":
Oxidoreductases
Transferases
Hydrolases
Isomerases
Ligases
Lyases
Enzymes get reaction over the hill.
Insulin: function
INsulIN stimulates 2 things to go IN 2 cells:
Potassium and Glucose.
Collagen concisely covered
COLLAGEN:
C-terminal propeptide (procollagen)/ Covalent
Cross links/ C vitamin/ Connective tissue/
Cartilage/ Chondroblasts/ Copper Cofactor
(Covalent Cross linking)
Outside the cell is where collagen normally
functions/ Osteoblasts/ Osteogenesis imperfecta
Lysyl hydroxylase/ Lysyl oxidase (oxidatively
deaminates lysyl and hydroxylysyl residues to form
collagen cross links, last biosynthesis step)
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HARD":
Headache/ Hepatomegaly
Anorexia/ Alopecia
Really painful bones
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See diagram.
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Malate-aspartate shuttle
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"MAD commute":
Malate in. Alpha-ketoglutarate and D (Aspartate)
out.
Vitamins: which are fat soluble
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Pyrimidines are Cytosine, Uracil, Thiamine and are one ring structures.
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Purines are double ring structures.
INsulin gets sugar INto cells- (Excess sugar is removed via urine.The
Romans noticed bees attracted to the urine of diabetics and coined the
term "diabetes" to describe the overflow of sugar.)
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