1 2 5HT D M H1, H2

FENOXIBENZAMIN antagonist> antagonist antagonist -act directa antagonist antagonist Feocromocitom,

A 2 PREsinaptici 5HT2 (VD) pe ms flebite, Raynaud
neteda
vasculara
- inhibits
reuptake of
released
norepinephrine
by presynaptic
adrenergic
nerve
terminals
FENTOLAMINA antagonist antagonist antagonist agonist agonist Feocromocitom,
5HT2 flebite, Raynaud
ERGOTOXINA antagonist antagonist partial antagonist -act directa Adjuvant HTA,
partial 5HT2 (VC) pe ms tulburari d eirigatie
neteda cerebrala
vasculara
ERGOTAMINA agonist partial - agonist antagonist/ migrena
vase partial//antagonis agonist partial
(Rang&Dale)// t 5HT1,
antagonist antagonist
5HT2
DIHIDROERGOTAM antagonist antagonist antagonist/ Migrena, hTA
INA agonist partial
5HT1
ERGOMETRINA antagonist/ antagonist/ antagonist slab Contractie ms uterina
agonist partial) agonist partial slab/ agonist - glob de siguranta,
partial 5HT1 delivrare placenta,
involutie incompleta a
uterului, hemoragii
postpartum
BROMOCRIPTINA Antagonist slab Antagonist agonist Parkinson
slab
METISERGID Agonist slab Agonist slab antagonist/ Migrena, tumori
agonist partial carcinoide
5HT2 producatoare de
serotonina
URAPIDIL antagonist agonist agonist 5HT1A agonist slab HTA
2 PREsinaptic
TOLAZOLINE antagonist Raynaud, HTP cu
sindrom de detresa
respiratorie la nn