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Christopher L. Hamill
90 Peter D. Angevine
Keith H. Bridwell
Sagittal Imbalance
the head and posterior over the pelvis, which in turn transmits
the force of the femoral heads via the acetabula. Although
there is not a single normal sagittal spinal contour, research
has demonstrated that there are relatively some conserved rela-
tionships between sagittal curves among patients without back
pain.1 Bernhard and Bridwell1 found that a well-balanced spine,
in general, has between 10 and 30 more lumbar lordosis than
thoracic kyphosis. There is also evidence to suggest that sagittal
alignment changes over time as the intervertebral disc and
facet degeneration leads to loss of lumbar lordosis and increas-
ing thoracic kyphosis. This process may be associated with the
progression of sagittal imbalance.6
RADIOGRAPHIC EVALUATION
The single most important study for the evaluation of sagittal
imbalance is a properly exposed lateral long-cassette (36-in.)
radiograph of the entire spine. The field of view should include
the entire spine and the base of the occiput and proximal
femurs. The optimal patient stance for obtaining these antero-
posterior (AP) and lateral radiographs has been established by
Horton et al.8 A comparison was made between three different
lateral radiographs with arm positioning varying between
straight out, partially flexed, and fully flexed in the clavicle
position. They found no view to be perfect. The clavicle posi-
tion gave superior visualization of T2, T12, and L5-S1 compared
with the 90 position. The clavicle position was superior to the
partially flexed position for visualizing T12 and for the overall Figure 90.1. Pelvic incidence (PI) pelvic tilt (PT) sacral slope
rating. They also found the clavicle position did provide the (SS). The PI is the angle of pain when perpendiculars are drawn to
best visualization of key landmarks without external support, the center of the sacrum and the femoral head.
which may affect the sagittal vertical axis. It is our practice to
use the clavicle position if patients can maintain their balance
in this position. This position entails fully flexed elbows with between the proximal sacral end plate and a horizontal refer-
the hands in a relaxed fist. This allows for the proximal inter- ence line. As these angles sum to PI (PI SS PT), they are
phalangeal joints to be placed carefully into the supraclavicular obviously inversely related (Fig. 90.1). The use of sacropelvic
fossa; the feet should be kept at shoulders width, knees in parameters has added to the clinicians understanding of the
extension, and hips extended. magnitude of sagittal misalignment. A greater PI necessitates
The most commonly used radiographic reference points for more lumbar lordosis to maintain sagittal balance. As the lum-
determining overall sagittal balance are the centrum of the C7 bar lordosis decreases, the patient may rotate the pelvis posteri-
body and the posterior superior corner of the sacrum. The hori- orly to maintain overall sagittal balance; this effectively extends
zontal distance between the vertical plumb line extending from the hips while increasing the PT and decreasing the SS. The
the C7 body and the posterior superior sacral corner is mea- limit of this compensatory mechanism is reached when the hips
sured. The body of C2 may also be used as the origin of the verti- are maximally extended within the acetabula. Further compen-
cal plumb line, but it may be more difficult than C7 to visualize sation is achieved with knee flexion. The result is a typical pos-
on long-cassette radiographs. By definition, radiographic posi- ture of a severely sagittally imbalanced patient who stands with
tive sagittal balance occurs when the C7 plumb line falls anterior flexed knees and hips that appear to be flexed but are actually
to the sacral reference point. If the plumb line is posterior to the maximally extended (Fig. 90.2A through 90.2D).
sacral reference point, the sagittal balance is negative. Supine AP and lateral radiographs can provide additional
The sacral pelvic alignment is an important aspect of sagittal information about the flexibility of the deformity. Analysis of
plane deformity, both for understanding its magnitude and for the spinal alignment in the local regions can be assessed on the
planning any surgical correction. The pelvic incidence (PI) is more coned-down views of the spine. Particular attention
an anatomically fixed measurement for each patient. It is should be paid to the flexibility in the areas of maximal defor-
defined as the angle between the line from the center of the mity as demonstrated by the changes in the intervertebral disc
femoral heads to the midpoint of the proximal sacral end plate height and angulation. Flexibility radiographs also may help
and the perpendicular bisector of the sacral end plate that distinguish the presence of nonunion and aid in preoperative
extends dorsocaudally.10 While the PI is constant in each indi- planning. It is important to remember that clinical and radio-
vidual, it is the sum of two variable component angles, the graphic flexibility studies do not typically demonstrate the max-
sacral slope (SS) and the PT. The PT is the angle between a imal spontaneous correction possible. However, careful preop-
vertical reference line through the centrum of the femoral erative flexibility evaluation will indeed help the surgeon to
head and the line from the center of the femoral head to the determine the rigidity of the deformity and whether an osteot-
midpoint of the proximal sacral end plate. The SS is the angle omy will be required to achieve adequate correction.
A B C
Sagittal Imbalance Type Global Sagittal Balance Global Coronal Balance Treatment Options
I Maintained Maintained Smith-Petersen
osteotomies, possibly
pedicle subtraction
osteotomy (PSO)
II Disrupted Maintained PSO, vertebral column
resection (VCR)
III Disrupted Disrupted VCR
A B C D
Figure 90.3. (A) Anteroposterior (AP) and (B) lateral scoliosis radiographs of a 43-year-old woman status
post 30 years Harrington instrumentation and fusion down to L4. Note the loss of midlumbar lordosis and
hyperextension of the L4-5 and L5-S1 disc. (C) AP and (D) lateral 2-year postoperative radiographs after the
patient had anterior discectomy, structural grafting, and multiple Smith-Petersen osteotomies.
A B C D
Figure 90.4. (A) Anteroposterior (AP) and (B) lateral scoliosis radiographs on a 17-year-old female
patient with 95 Scheuermann kyphosis. (C) AP and (D) lateral 2-year postoperative radiographs after the
patient had multiple typical Smith-Petersen osteotomies and posterior instrumentation and fusion. No ante-
rior procedure was performed.
a middle-aged or older patient who, with multiple surgeries, patients with symptomatic sagittal imbalance. Although symp-
had the spine fixed in a hypolordotic position. This leads to tomatic improvement may be achieved in some patients with
premature degeneration of the upper lumbar or distal thoracic nonoperative treatment, the likelihood of a dramatic long-term
spine. This will again lead to the patient not being able to stand improvement of symptomatic sagittal imbalance without sur-
straight and is eventually pitched forward. gery is probably lower than for other degenerative conditions.
More recently, a type III category has been added to the clas- The underlying structural changes may be the factor leading to
sification of sagittal imbalance. Patients with a type III deformity this unsatisfactory response to nonoperative management.
have both coronal and sagittal imbalance resulting from a major
deformity in both planes. This deformity is not as common as
type I and type II sagittal imbalances. The correction of these PREOPERATIVE PLANNING
complex deformities can be quite difficult as both the coronal
and sagittal planes have to be taken into consideration. The complication rates after revision spinal surgery have been
Coronal imbalance has also been categorized into two dif- shown to be as high as 60%, with approximately half of those
ferent groups. Type I coronal imbalance includes patients in having residual sagittal imbalance.2 To minimize the likelihood
whom one shoulder, typically the right, is high and the ipsilat- of postoperative sagittal imbalance, the preoperative planning
eral pelvis is low. In this circumstance, the coronal deformity process must be rigorous and include a preoperative assess-
may be corrected by simply shortening the convexity of the ment of sagittal alignment and a determination of the distal
deformity. In a type II coronal deformity, the shoulder relation- limit of the fusion. Important intraoperative factors include the
ship to the pelvis is such that it cannot be corrected simply by use of segmental instrumentation and avoidance of distraction,
shortening one side of the spine (Fig. 90.5). especially in the lumbar spine. Intraoperatively, the patient
should not be positioned in a manner that decreases lumbar
lordosis. Hip extension has been shown to be essential to the
TREATMENT preservation of anatomical lumbar lordosis.12
Appropriate preoperative clinical and radiographic evalua-
Similar to all degenerative painful conditions, nonoperative tion will provide the surgeon with the information necessary to
management should be the initial treatment of choice for plan the surgical procedure or procedures for correction of the
A B C
Figure 90.5. (A) Anteroposterior (AP) and (B) lateral scoliosis radiographs on
a patient with type 3 sagittal plane imbalance with marked coronal and sagittal
imbalance. (C) AP and (D) lateral radiographs: patient now 1-year status post
D asymmetric pedicle subtraction osteotomy.
Smooth Kyphosis Sharp Angular Kyphosis Smooth Kyphosis Sharp Angular Kyphosis
Figure 90.6. Treatment decision tree for type I and II sagittal imbalance. PSO, pedicle subtraction
osteotomy; SPO, Smith-Petersen osteotomy; VCR, vertebral column resection.
sagittal plane deformity. The location of the deformity, its angu- and previous Harrington instrumentation to the L4 or L5 level.
larity and flexibility, and the magnitude of global sagittal imbal- These patients do not have significant sagittal imbalance and
ance are the main factors that determine the operative strategy. therefore with multiple SPOs, reestablishment of lumbar lordo-
At one extreme is a stiff angular deformity in the thoracolumbar sis with restoration overall global balance can be achieved. If
region with significant global sagittal imbalance, which may best bone-on-bone contact is established with the SPOs, anterior
be treated with a PSO or a VCR. On the other hand, a flexible, reconstruction is usually not required.
sweeping thoracolumbar hyperkyphosis with relatively preserved
global sagittal balance may be treated with multiple SPOs. The
decision-making process regarding the type and location of the PEDICLE SUBTRACTION OSTEOTOMY
corrective osteotomy depends on the deformity and, in reopera-
tions, the presence and location of any pseudarthrosis. An osteot- The PSO is a powerful technique for the correction of type II
omy through a pseudarthrosis can be used to obtain the correc- sagittal imbalance. This procedure is most commonly per-
tion of the deformity and address the nonunion while minimizing formed in the lumbar spine. Although it can be performed in
the number of fusion surfaces. In general, corrective osteotomies the thoracic spine, the amount of correction obtained is not as
should be performed at the site of maximal deformity to achieve significant as it is in the lumbar spine. The decancellation pro-
maximum correction. Typically, the L2 or L3 level is the focal cedure is a three-column posterior closing wedge osteotomy
point of the anatomical lumbar lordosis (Fig. 90.6). hinging on the anterior cortex. This also has been described
previously by Heinig as the eggshell procedure.7 The operative
technique involves removal of all posterior elements at the level
SMITH-PETERSEN OSTEOTOMY of the correction including the superior and inferior facet
joints and the pedicles. The posterior-based wedge is removed
In 1945, Smith-Petersen et al11 described and performed the to allow correction through a shortening, posterior closure.
first osteotomy for correction of flexion deformity. This proce- The osteotomy can be closed down through various maneuvers
dure has been modified multiple times. The basic premise is including extension of the patients hips on the operative
that correction is achieved through shortening of the posterior frame, cantilever bending, and compression across the osteot-
column with resulting anterior osteoclasis leading to lengthen- omy site, as Buchowski et al5 have shown. Neural compression
ing of the anterior column. The ideal patient for SPO is one leading to a temporary or permanent neurological deficit has
with a long, rounded, smooth kyphosis without any significant been reported to occur in as many as 11% and 3% of patients,
segmental angularity, such as most Scheuermann kyphosis respectively.5 To ensure that the neural elements are not com-
deformities. Multiple fixation points and mobile disc spaces are pressed, the central canal is widened while not compromising
required. As a general rule, 1 of correction can be maintained the stability of bone-on-bone contact.
for each millimeter of posterior bone resection, with the maxi- The advantages of the PSO procedure include the ability to
mum correction per level being approximately 10. The ideal achieve significant (typically, 30 to 35) correction through
candidate should have good bone stock, given the posterior one level, preservation of the anterior column, an excellent
compression required to correct the deformity. The anterior potential for union secondary to the abundant cancellous
column lengthening creates anterior gaps, which may require bone-on-bone contact and the ability, with asymmetric resec-
structural grafting to prevent implant loosening and maintain tion, to achieve or maintain coronal balance. The ideal candi-
the correction in the long term, particularly if the gap is greater dates for PSOs are patients with substantial (10 to 12 cm)
than 10 mm in height. Multiple SPOs can result in a harmoni- sagittal imbalance, a sharp angular kyphosis, and circumferen-
ous reduction of hyperkyphosis or restoration of lumbar lordo- tial fusion. The PSO can be performed through areas of rota-
sis. Aside from those with a smooth kyphosis, the other candidate tional deformity or prior laminectomy. The PSO is also the
for this procedure is a patient with a type I sagittal imbalance ideal procedure for patients with ankylosing spondylitis.
COMPARISON OF OSTEOTOMIES
The SPO will achieve approximately 1 of correction per milli-
meter of resection with a maximum of 10 per level. The opti-
mal candidates are those with good bone stock, those with
mobile discs, and those patients in whom harmonious restora-
tion of lumbar lordosis is required. The drawbacks of the pro-
cedure are that it is an anterior columnlengthening procedure
and may require anterior exposure to fill in the gaps. The
patients with ankylosed disc spaces are not candidates for this
procedure, as well as those with ankylosing spondylitis or sig- B
nificant calcification of the great vessels.
The PSO has the ability to obtain approximately 30 to 35
of correction per osteotomy level. It can achieve sagittal and
coronal correction with high union rates and it is, again, a
posterior-only procedure. The drawbacks include the technical
demands of the procedure, higher rate of blood loss, and a risk
of debilitating neurological injury. The contraindications to
this procedure are those patients with anterior instrumentation
at the same level.
With a VCR, the amount of correction is variable but does A C
hold the greatest potential for correction in both the sagittal
Figure 90.7. (A) The initial resection of the posterior elements
and the coronal planes by shortening of the spinal column.
and surrounding of the pedicles. The amount of the bone resected is
The procedure theoretically will relieve neurovascular demonstrated in the lateral view (B) in this figure. (C) Schematic dor-
tension; however, this is a very demanding procedure and sal view. (Reprinted with permission from Bridwell KH, Lewis SJ,
neurological complication rates, while not reported to date, Rinella A, Lenke LG, Baldus C, Blanke K. Pedicle subtraction osteot-
do pose a significant risk when performing the procedure omy for the treatment of fixed sagittal imbalance: surgical technique.
(Table 90.2). J Bone Joint Surg Am 2004;86A(1):4450.)
A B
A B
Figure 90.10. (A) Greenstick fracture and resection of the poste-
Figure 90.8. (A) Decancellation of the pedicles and the vertebral rior vertebral cortex. (B) Lateral schematic view. (Reprinted with per-
body. (B) Lateral schematic. Red area shows cancellous bone to be mission from Bridwell KH, Lewis SJ, Rinella A, Lenke LG, Baldus C,
removed from vertebral body. (Reprinted with permission from Blanke K. Pedicle subtraction osteotomy for the treatment of fixed
Bridwell KH, Lewis SJ, Rinella A, Lenke LG, Baldus C, Blanke K. Pedi- sagittal imbalance: surgical technique. J Bone Joint Surg Am
cle subtraction osteotomy for the treatment of fixed sagittal imbal- 2004;86A(1):4450.)
ance: surgical technique. J Bone Joint Surg Am 2004;86A(1):4450.)
performed are the SPO, PSO, and VCR. The advent of third-
generation instrumentation and appropriate positioning should
lead to the decrease in the development of flatback deformity.
These newer techniques have also improved our ability to cor-
rect the problem when it occurs. Each osteotomy has inherent
risk versus benefits and should be chosen with careful preopera-
tive consideration.
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A B 13511358.
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