Documente Academic
Documente Profesional
Documente Cultură
Alpesh A. Patel
Classification of Cervical
Spine Injury
1381
ALL, anterior longitudinal ligament; AO, Arbeitsgemeinschaft fr Osteosynthesefragen; PLL, posterior longitudinal ligament
injury.3,19 While this supports nonoperative treatment, the defi- The White and Panjabi system is the first to designate neuro-
nition of stability is broad, overlooking many of the details logic status as a component of cervical stability and the first to
involved with the management of acute cervical trauma and provide radiographic measurements as criteria for instability. The
acute neurological injury. In addition, it is a purely retrospec- system is limited in its usefulness, however, by the stretch test,
tive description, based upon functional outcomes and, there- which is now rarely required due to current imaging technologies
fore, provides no prognostic information. and an improved understanding of soft tissue disruptions. It is
Holdsworth, through a review of more than 1000 patients, further limited by the number of radiographic criteria present,
divided fractures into two large groups (stable and unstable) the disproportionate weight given to radiographic criteria over
based primarily upon disruption of the posterior ligament ligamentous and neurological status, and unproven reliability.
complex.7 Stable patterns included wedge fractures, burst frac- Whereas others had classified injuries based on concepts of
tures, and extension injuries; unstable patterns included dislo- stability, Allen et al developed a mechanistic classification sys-
cation, rotational-fracture dislocation, and shear injuries. tem.1 Based upon a review of 165 patients with subaxial cervical
Although based solely on radiographs, Holdsworth astutely trauma, the authors divided injuries into groups based upon a
identified the critical importance of the posterior cervical liga- common mechanism of injury with emphasis on a progression
ments in spinal stability. His description fell short, however, due of severity within each mechanism. Six main categories were
to a lack of anatomic fracture detail and by not accounting for derived based upon inferred force vectorscompressive flex-
the neurologic status of the patient. ion, vertical compression, distractive flexion, compressive
Louis defined cervical spinal stability upon three anatomic extension, distractive extension, and lateral flexion. This was
pillars (columns)one anterior (vertebral body, intervertebral later modified by Harris et al to include rotational vectors in
disc) and two posterior (each lateral mass).9 Although concep- both flexion and extension.6
tually easy to understand, this remains primarily a descriptor of The system is comprehensive, detailing an array of potential
bony injury location, without accounting for spinal alignment cervical injuries. The system is also appropriately organized by
or ligamentous injury and without any implication as to injury severity and can, therefore, aid in injury stratification. The sys-
severity. tem is, however, also handcuffed by the multitude of options.
White and Panjabi through a review of clinical cases and in Furthermore, the system is fundamentally limited because it is
vitro biomechanical testing have suggested a point-based clas- based upon mechanisms that are inferred from the recoil posi-
sification system for cervical trauma.20 Radiographic criteria, tion of the spine on radiographic imaging. This leaves the clas-
physical examination (including neurological status), and a sification open to interpretation and has been reflected in the
stretch test are required and have an assigned point system. poor to fair reliability of this system.17
The stretch test, involving sequential traction, aims to quantify The AO classification of spinal trauma defines injuries into
disc or ligamentous disruption through radiographic changes. one of three large categories (A, B, C) with nine subgroups.10
Type A injuries are compression injuries of the anterior col- The reliability of the system was tested on 35 cervical spine
umn; type B injuries involve distraction injuries, with or without injured patients.2 The radiographs and computed tomography
angulation; type C injuries additionally involve a translational (CT) scans were reviewed by 15 investigators of varying experi-
or rotational component. Subgroups are further defined ence and the CSISS measured. The reliability was assessed by
according to the standard AO 3 3 system. determining the mean intraobserver and interobserver differ-
The AO system provides a well-defined, well-organized ences using intraclass correlation coefficients (ICCs). For this
means of describing a broad array of injury patterns. metric, any score greater than 0.75 indicates excellent reliabil-
Classification is based upon severity of injury and can thereby ity. The intraobserver ICC was 0.98, and the interobserver ICC
guide treatment. The system also allows for a universal lan- was 0.88, both indicating excellent reliability. No difference was
guage that can improve communication between treating phy- noted based on experience of the examiner. The worst cases
sicians. The complexity of the AO system, specifically the array with the greatest variance in scores where in patients with anky-
of subgroups, limits its usefulness in routine clinical care. The losed spines or those with subtle ligamentous injury.
large AO categories (A, B, C) have additionally demonstrated Validity indicates that the test or instrument is correctly
only poor to moderate reliability, with results worsening when gauging reality. In most cases, this requires that the results be
AO subcategories are tested.14,21 compared with a gold standard. Validity was tested by compar-
ing the CSISS to the presence of neurologic injury and whether
surgery was performed (Figs. 128.2A to D). All 14 patients with
MODERN CLASSIFICATION SYSTEMS scores of 7 or greater had surgery whereas only 3 out of 20
with scores below 7 had surgery (Figs. 128.3A to D). All three
THE CERVICAL SPINE INJURY SEVERITY SCORE of these patients had a neurologic deficit. Furthermore, 65% of
patients with scores greater than 7 had neurologic deficits
The Cervical Spine Injury Severity Score (CSISS) was devel-
compared with only 15% with lower than 7 scores.
oped to quantify the degree of traumatic instability.2,12 The sys-
In summary, the CSISS causes the surgeon to critically exam-
tem is based on a four-column model of the cervical spine and
ine all components of the injury and can reliably measure the
an analog scale to assess injury of each column (Figs. 128.1A
degree of instability. It is easy to use and can be based on com-
and B). The four columns are anterior, each lateral pillar, and
puted tomography (CT) and magnetic resonance imaging
the posterior osseous ligamentous complex (Fig. 128.1A). The
(MRI).
anterior column consists of the body, disc and annulus, and the
anterior and posterior longitudinal ligaments. Each lateral pil-
lars includes the pedicles, lateral masses with facet articulations, SUBAXIAL CERVICAL INJURY CLASSIFICATION
and facet capsules. The posterior column includes the lamina,
spinous processes, ligamentum flavum, and all the nuchal liga- The Subaxial Cervical Injury Classification (SLIC) system and
ments. severity score have been described by Vaccaro et al as a novel
Each column is scored independent of the others using an system to define subaxial cervical trauma (C3-C7).17 It is an
analog scale from 0 to 5 (Fig. 128.1B). A zero is no injury and adaptation of a thoracolumbar injury classification system
five is the worst injury that could occur to that column. Scores described by Vaccaro et al in an attempt to standardize
in-between are based on degree of displacement. For example, approaches to and descriptors of spine trauma across anatomic
a nondisplaced fracture is graded as a 1, while a subluxation regions.18
of 3 mm would be graded as a 3. Fractional values can be The SLIC system describes the injury by spinal level, injury
used. The score for each column is summed giving a potential morphology, bony description, discoligamentous status, and
score from 0 to 20. neurological examination. The SLIC system identifies three
A B
C D
Figure 128.2. (A) A 27-year-old man with facet fracture of C6 and C7 body and right facet. The sagittal
computed tomography (CT) demonstrates the body fractures and opening between spinous processes
(arrows). His anterior column is scored 2.0 for slightly fractures without vertebral subluxation. The posterior
column is disrupted and scored 4.0. (B) Axial CT. Arrow indicates body fracture of C7. (C) Left pillar was
scored 2.0 for facet subluxation (arrow). (D) Right pillar was scored 3.0 for having both subluxation and supe-
rior facet fracture. The overall Cervical Spine Injury Severity Score was 11.0, and the patient was treated by
posterior fusion.
critical components in subaxial cervical spine trauma: injury advanced imaging characteristic. Injury morphology is classi-
morphology, discoligamentous injury, neurological status. fied as compression, distraction, or rotation/translation.
Compression injuries are defined by a visible loss of height
of the vertebral body or disruption through the vertebral end
Injury Morphology
plate. This includes traditional compression and burst frac-
The injury morphology defines the structural relationship of tures, sagittal or coronal plane fractures of the vertebrae, and
the vertebral bodies to each other in terms of anterior ana- teardrop, or flexioncompression fractures.
tomical support, soft tissue structures, facet relationships, and The distraction injury pattern is readily identified by
overall alignment as determined by plain radiographic and anatomical dissociation in the vertical axis. A representative
A B
example would be a hyperextension injury causing disruption The rotation/translation injury is defined by horizontal dis-
of the anterior longitudinal ligament (ALL) with subsequent placement of one vertebral body of the subaxial cervical spine
widening of the anterior disc space. Posterior element fractures with respect to another other. Biomechanical work suggests that
(facet, lamina, spinous process) may also be present. Bilateral adequate thresholds for stability are less than 3.5 mm of displace-
perched facets or other kyphotic deformities of the spine, ment or relative angulation of less than 11.20 It is typified by
through a tensile failure of the ligamentous restraints, repre- unilateral and bilateral facet dislocations or fracture-dislocations,
sent another clinical example of the distraction morphology. fracture separation of the lateral mass (floating lateral mass)
with vertebral subluxation, and bilateral pedicle fractures with Injury Severity Score
vertebral subluxation (traumatic spondylolisthesis).
A numeric value has been assigned to each descriptor within
these three critical components. Injury patterns that are known
Discoligamentous Complex to result in worse outcomes or require urgent surgical interven-
The discoligamentous complex (DLC) component is based tion (spinal instability, neurological injury) are weighted to
upon integrity of the intervertebral disc, anterior and posterior receive greater point values. These three numbers are summed
longitudinal ligaments, interspinous ligaments, facet capsules, to provide an overall SLIC score. The resultant score can then
and ligamentum flavum. This is a descriptor unique to the be used to guide treatment of that particular injury. Surgical
SLIC system and is divided into three categories: intact, inde- versus nonsurgical treatment is determined by a threshold
terminate, and disrupted. Disruption of the DLC may be repre- value of the SLIC severity score. If the total score is less than
sented by abnormal facet alignment (articular apposition four (1 to 3), nonoperative treatment is suggested. If the total
50% or diastasis 2 mm through the facet joint), abnormal is greater than or equal to five (5), operative treatment is rec-
widening of the anterior disc space either on neutral or exten- ommended. This may consist of realignment, neurological
sion radiographs, translation or rotation of the vertebral bod- decompression (if indicated), and stabilization. A total score of
ies, or kyphotic alignment of the cervical spine. Indeterminate four (4) may be treated operatively or nonoperatively (Figs.
injury may exist when radiographic disruption of the DLC is 128.4A to D).
not otherwise obvious on radiographic or CT imaging but a In instances of multiple levels of cervical trauma, each level
hyperintense signal is found through the posterior ligamentous is treated as a separate injury and SLIC scores are calculated
regions on T2-weighted MRI images, suggesting edema and independently for each level. If a single level has multiple injury
injury. Intact DLC is defined by a lack of radiographic evidence patterns, only the most severe injury is considered for scoring.
of abnormal spinal alignment in addition to normal disc space For example, if the injured level showed signs of both compres-
and ligamentous appearance. sion and rotation, morphology would be scored as rotation/
translation. The descriptive identifiers and the point scores for
each SLIC category are summarized in Table 128.2.
Neurological Status
The neurologic status of the patient is often the most influen-
tial component of medical decision making. In addition, it can CLINICAL USE OF MODERN
be inferred that neurologic injury is a critical indicator of the CLASSIFICATION SYSTEMS
degree of spinal column injury. The neurologic status, another
unique component of the SLIC system, is defined as one of These two classification systems are designed to aid treatment
the following: root injury, complete cord injury, or incomplete decisions as presented in Figure 128.5. Greater scores generally
cord injury. An additional modifier, continuous cord compres- indicate that surgery is indicated as attested by the primary
sion, is described in the setting of either complete or incom- authors of the system. However, the reader should consider
plete spinal cord injury with ongoing spinal cord compression these systems as tools and that each patient should be evaluated
due to disc, bone, ligamentum flavum, hematoma, or other on its own merits. Both systems require further validation to
structures. establish their role in evaluating spinal injured patients.
Points
Morphology No Abnormality 0
Compression 1
Burst 1 2
Distraction (e.g., facet perch, hyperextension) 3
Rotation/translation (e.g., facet dislocation, unstable teardrop, or advanced 4
staged flexion compression injury)
Discoligamentous Complex (DLC) Intact 0
Indeterminate (e.g., isolated interspinous widening, MRI signal change 1
only)
Disrupted (e.g., widening of anterior disc space, facet perch or dislocation, 2
kyphotic deformity)
Neurological Status Intact 0
Root injury 1
Complete cord injury 2
Incomplete cord injury 3
Continuous cord compression (in setting of a neurologic deficit) 1
A B
C D
Figure 128.4. Subaxial Cervical Injury Classification (SLIC): Translational C4-C5 bilateral facet disloca-
tion with disruption of the discoligamentous complex, complete spinal cord injury. (A) Sagittal computed
tomography (CT) shows greater than 50% vertebral translation and wide interspinous distraction. (B) Axial
CT demonstrating bilateral facet dislocation. (C, D) Ventral cord compression and disruption of interverte-
bral disc and posterior ligamentous structures are seen on (C) T2 and (D) short TI inversion recovery
(STIR) magnetic resonance imaging (MRI). SLIC Severity Scale:
Morphology
Rotation/Translation 4 pts
DLC
Disrupted 2 pts
Neurological Status
Complete Spinal Cord Injury 2 pts
SLIC Score 4 2 2 8 (operative)
History
Physical examination
Neurologic examination
Plain radiographs
CT scan (with reconstructions) MRI
Unexplained neurologic deficits
Possible ligamentous injury
Neurologic deterioration
Preoperative evaluation
Injury type