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6. Which of the following drug blocks the sodium channel and dissociates
slowly?
a. Quinidine b. Lignocaine c. Flecainide d. Procainamide
8. In HPLC, which pump gives a mobile phase flow rate dependent on column
permeability?
a. Constant pressure pumps b. Constant displacement pumps
c. Reciprocating pumps d. Pneumatic pumps
9. Which of the following organism is the Source for amphotericin?
a. Streptomyces immodosus b. Streptomyces nodosus
c. Streptomyces griseus d. Streptomyces aureofaciens
10. Which of the following drug produces gastric irritation after
micronization?
a. Phenobarbital b. Tetracycline
c. Erythromycin d. Nitrofurantoin
11. Adult dose of a drug is 150 mg/kg and the drug is available as tablets of 2
mg strength. Calculate the dosed required for a boy of age 14 yrs and weight
of 35 kg?
a. 74.9 mg b. 78 mg c. 82 mg d. 80 mg
16. Bladder toxicity is the side effect of which of the following drug?
a. Vincristine b. Cyclophosphamide c. 5-Flouro Uracil d. Doxorubicin
18. If the half life for decomposition of a drug is 12 hrs, how long will it take
for 125 mg of the drug to decompose by 30 %? Assume that the drug follows
first order kinetics at constant temperature.
a. 6.1 hr b. 8.2 hr c. 7.9 hr d. 5.5 hr
21. Which of the following is the biosynthetic origin for an amino alkaloid
Ephedrine?
a. Phenyl alanine and Ornithine b. Phenyl alanine and Pyruvic acid
26. Calculate the amount of sodium chloride required to make 1.5 % solution of
pilocarpine HCl isotonic with tear secretion? (Freezing point depression of 1 %
pilocarpine HCl is - 12C and that of sodium chloride is - 0.576C).
a. 0.564 % w/v b. 0.712 % w/v c. 0.224 % w/v d. 0.693 % w/v
27. Lecithin is incorporated in shampoos as
a. Conditioning agent b.Clarifying agent
34. Which of the following method is suitable for the sterilization of bone and
tissue transplants?
a. Ionizing radiation b. Gaseous sterilization
a. b. c. d.
39. Which of the following is not an example for synthetic hair dye?
a. Para toluene diamine b. p-phenylenediamine
40. Which of the following drying method under controlled conditions results
in changes in chemical composition?
a. Processing b. Mulching c. Curing d. Fermentation
42. Which of the following is the starting material for the biosynthesis of l-
Hyoscyamine?
a. Tyrosine b. Alanine c. Valine d. Phenyl alanine
53. Which of the following is used for the assessment of growth in suspension
culture?a. Packed cell volume
58. Statto - Oto method is used for the isolation of which of the following?b.
Glycosides
59. Which of the following disease susceptibility can be determined by Shick test?
b. Diphtheria
61. Which of the following is the IUPAC name for Progesterone? d. Pregn-4-ene-
3, 20-dione
62. Which of the following is an example for natural emulsifying agent of animal
origin?d. Gelatine
63. Which of the following alkaloidal drug is having pseudo parenchyma?d. Ergot
64. Basophiles are having receptors for which of the following antibodies?d. Ig E
68. Which part of the umbelliferous fruits is having high content of volatile oils?a.
Mesocarp
73. Which of the following are identified by using Borax test?b. Barbaloins
74. Iron content of gelatine used for the preparation of soft capsule should not be
more than a. 15 ppm
79. Which of the following is readily used for the filling of pelletized or granular
material into Capsules?b. Rotofil
83. Which of the following medium is used for differentiation of lactose and non -
lactose fermentors?a. Mac Conkey's medium
84. Which of the following odour is developed when ergot powder is treated with
sodium hydroxide?d. Triethyl amine
85. Betamethazone and Dextromethazone are a. Epimers c. Optical isomers d.
Both a and c
86. LAL (Limulus Amebocyte Lysate) isa. An in vitro test for detecting
pyrogenic endotoxins
87. Which of the following allied drugs of Senega does not contain Saponin
c. Polygala chinesis
88. How many signals are produced by CH3-CH2 - CH2 -CO-CH2 -CH3 in NMR
spectroscopy?d. 2
92. Which of the following drug is not bound to Warfarin binding sites? a. Phenyl
butazone b. Sulfamethizolec. Bilirubin d. Ketoprofen
95. Which of the following drug is designed as prodrug for improved taste?b.
Clindamycin palmitate ester
97. Which of the following drug inhibits the Prolactin level? b. Dopamine
98. Which of the following is obtained by fusion of Morphine with potassium
hydroxide? c. Proto Catechuic acid
99. A solution of drug was prepared freshly at a concentration of 300 mg/ml. After
25 days of storage at 25 OC, the drug concentration in the solution was found to be
120 mg/ml. The drug assumed to undergo zero-order kinetics. Calculate the
reaction rate constant?
a. 7.2 mg/ml/day b. 62.5 mg/ml/day c. 0.72 mg/ml/day d. 6.25 mg/ml/day
KEY:
1 c 2 c 3 A 4 a 5 d 6 c 7 a 8 a 9 b 10 d
11 a 12 b 13 D 14 b 15 a 16 b 17 b 18 a 19 c 20 c
21 b 23 A 24 d 25 d 26 a 27 a 28 a 29 a 30 c
31 b 32 a 33 c 34 a 35 d 36 a 37 b 38 b 39 d 40 c
41 a 42 d 43 a 44 c 45 d 47 a 48 a 49 b 50 a
51 a 52 a 53 a 54 d 55 c 56 a 57 c 58 b 59 b 60 a
61 d 62 d 63 d 64 d 65 c 66 a 67 a 68 a 69 c 70 a
71 c 72 b 73 b 74 a 75 a 76 c 77 b 78 c 79 b 80 d
81 c 82 a 83 a 84 d 85 d 86 a 87 c 88 d 89 a 90 b
91 b 92 d 93 b 94 d 95 b 96 a 97 b 98 c 99 a
1 c 21 b 41 b 61 d 81 b
2 b 22 b 42 c 62 d 82 d
3 b 23 a 43 c 63 b 83 b
4 d 24 b 44 a 64 a 84 b
5 b 25 c 45 a 65 c 85 b
6 c 26 d 46 b 66 b 86 a
7 d 27 b 47 d 67 b 87 d
8 a 28 d 48 b 68 c 88 c
9 d 29 d 49 c 69 b 89 c
10 b 30 d 50 d 70 c 90 c
11 c 31 d 51 b 71 a 91 c
12 c 32 c 52 d 72 d 92 d
13 c 33 b 53 b 73 c 93 c
14 d 34 b 54 d 74 c 94 a
15 a 35 c 55 d 75 c 95 c
16 a 36 d 56 d 76 b 96 b
17 c 37 c 57 d 77 a 97 a
18 d 38 b 58 c 78 d 98 b
19 a 39 a 59 b 79 c 99 c
20 d 40 b 60 c 80 b 100 a