Medication Indication
Name
Generic Name: -Indicated in the
Oxacillin treatment of infections
Classification: caused by penicillinase
Penicillin producing staphylococci
Frequency: which have demonstrated
susceptibility to the drug.
Dosage: Cultures and
375g susceptibility tests should
be performed initially to
Route: determine the causative
TIV organism and its
susceptibility to the drug.
http://www.rxlist.com/oxa
cillin-drug/indications-
dosage.htm
Mechanism of Action
-A penicillinase
resistant penicillin that
inhibits cell-wall synthesis
during microorganism
multiplication; bacteria
resists penicillins by
producing penicilllinase
enzymes that convert
penicillins to inactivate
penecillic acids. Oxacillin
resists these enzymes.
Contraindication Adverse Nursing Responsibilities
Reaction
-Contraindicated CNS: -Side effects may
with allergies to Lethargy,halluci beexperienced, suchas:
penicillins,cephalosp nations, seizures upset stomach,nausea,
orins, or other GI: diarrhea(small
allergens Glossitis, frequentmeals),
stomatitis,gastrit mouthsores
-Contraindicated to is, sore (performfrequent
mouth,furry or mouthcare) and pain
patiemt with
black hairy atinjection site.
hypersensitive o tongue,
drugs and its nausea,vomiting,
diarrhea,abdomi -Report difficulty
contents
nal pain, of breathing,
bloodydiarrhea, rashes,severe
enterocolitis,pse diarrhea,severe pain
udomembranous atinjection site,mouth
colitis, sores.
nonspecifichepat
itis -Finish entire courseof
GU: therapy asprescribed
nephritis-
oliguria,proteinu
ria,
hematuria,casts,
azotemia, pyuria
Hematoogic:
anemia,thrombo
cytopenia,leukop
enia,
neutropenia,prol
onged bleeding
time(more
common
thanwith other
penicillinase-
resistant
penicillins)
Hypersensitivit
y:
rash,fever,
wheezing
 Medication Indication Mechanism of Action Contraindication Adverse Nursing Responsibilities
Name Reaction

Generic Name: Parenteral: Treatment Clindamycin (Cleocin) is Contraindicated CV: Hypotens -Assess Site of
Clindamycin an antibiotic used for infection or acne;
of septicemia caused with allergy ion, cardiac
skin color, lesions;
Classification: by staphylococci, serious infections caused to clindamycin, arrest (with
BP; R, adventitious
antibiotic streptococci; by susceptible strains of history rapid IV sounds; bowel
acute hematogenous of asthma or infusion) sounds, output, liver
Frequency: anaerobes, streptococci,
osteomyelitis; other GI: Severe evaluation; complete
staphylococci, blood count, renal
adjunct to surgical allergies, tartrazi colitis,
Dosage: pneumococci; reserve use and liver function
treatment of chronic ne (in 75- and including pse
tests
300mg bone and joint for penicillin-allergic 150-mg udomembra
infections due to patients or when penicillin capsules); nous colitis,
Culture infection
Route: susceptible is inappropriate; less toxic hepatic or renal nausea,
before therapy.
TIV organisms; do not antibiotics (erythromycin) dysfunction; vomiting, diar
Administer oral drug
use to lactation. rhea,
should be considered. with a full glass of
treat meningitis; abdominal
water or with food to
does not cross the pain,
Nurse Labs prevent esophageal
bloodbrain barrier. esophagitis,
irritation.
anorexia, jaun
dice, liver
Do not give IM
function
injections of more
changes
than 600 mg; inject
Hematologic
deep into large
: Neutropenia muscle to avoid
, leukopenia, serious problems.
agranulocytos
is, eosinophili Do not use for minor
a bacterial or viral
Hypersensiti infections.
vity: Rashes,
urticaria to an Monitor renal and
aphylactoid re liver function tests,
actions and blood counts
Local: Pain with prolonged
following therapy.
injection, indu
ration and
sterile
abscess after
IM
injection, thro
mbophlebitis
after IV use