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Solubility: practically insoluble in water; freely soluble in

acetone, chloroform, ethanol, ether, and vegetable oils;


soluble in ethanol (95%).
Solubility Practically insoluble in water; soluble in ethanol (95%).
Miscible with acetone, chloroform, ether, and vegetable oils.

Solvent Solubility at 208C


Chloroform Practically insoluble
Ethanol 1 in 50
Ethanol (95%) 1 in 25
Ether Practically insoluble
Fixed oils Practically insoluble
Glycerin 1 in 1000
Propylene glycol 1 in 20
Water 1 in 3.5

Solvent Solubility at 208C unless otherwise stated(1)


Acetone 1 in 15
Chloroform 1 in 3300
1 in 11 at 608C
Cottonseed oil 1 in 1670
Ethanol 1 in 8
1 in 1.7 at 708C
Ethanol (95%) 1 in 9.3
Ethanol (50%) 1 in 2500
Ether 1 in 132
Methanol 1 in 5.5
1 in 1.7 at 608C
Olive oil 1 in 3300
Peanut oil 1 in 3300
Propan-2-ol 1 in 20
1 in 5 at 708C
Sunflower oil 1 in 3300
Water Practically insoluble
1 in 500 at 708C
1 in 100 at 1008C

Solubility Practically insoluble in water; soluble in methanol;


freely soluble in 550% aqueous ethanol, propylene glycol,
chloroform, ether, hexane, cottonseed oil, peanut oil, soybean
oil, glyceryl monooleate, and lard, and in solutions of alkali
hydroxides.
Solubility Practically insoluble in water, glycerin, propylene
glycol, solutions of alkali hydroxides, and dilute aqueous
mineral acids. Freely soluble in acetone, benzene, ethanol
(95%), ether, methanol, toluene, fixed oils, and mineral oil.
More soluble than butylated hydroxyanisole in food oils and
fats.

Solubility 1 in about 1 of water by volume at normal temperature


and pressure.

Solubility: practically insoluble in ethanol (95%) and water.


Solubility in water is increased by the presence of
ammonium salts or carbon dioxide. The presence of alkali
hydroxides reduces solubility.

Solubility Soluble 1 in 1 part of ethanol (95%) and 1 in 1 of


water; sparingly soluble in ether.

Solubility Soluble 1 in 6.5 of water. The sodium salt is less soluble


in water than the free acid.

Solubility Miscible with chloroform, ethanol (95%), ether, fixed


oils, liquid paraffin, and most other organic solvents; practically
insoluble in water.

Solvent Solubility at 208C unless otherwise stated


Acetone 1 in 58 at 308C
Benzene Very slightly soluble
Carbon tetrachloride Very slightly soluble
Chloroform Very slightly soluble
Ethanol 1 in 28
Ethanol (95%) 1 in 17 at 308C
Ether Slightly soluble
1 in 139 at 258C
Olive oil Very slightly soluble
Propylene glycol 1 in 33
Water 1 in 200
1 in 432 at 08C
1 in 303 at 108C
1 in 159 at 258C
1 in 94 at 408C
1 in 42 at 608C
1 in 10 at 1008C

Solubility: soluble 1 in 1 part of ethanol (95%) and 1 in 1 of


water; sparingly soluble in ether.

Solvent Solubility at 208C unless otherwise stated


Ethanol (95%) Very slightly soluble
Ether Insoluble
Water 1 in 55 at 08C
1 in 30 at 258C
1 in 16.5 at 508C
1 in 9.5 at 758C
1 in 5.7 at 1008C

Solubility Miscible with ethanol (95%); freely soluble in water;


practically insoluble in ether.

Solubility Miscible with ethanol (95%) and water with the


evolution of heat.

Solubility Soluble 1 in 2.2 of water; practically insoluble in


ethanol (96%)

Solubility Miscible with chloroform, ethanol (95%), ether, and


water.

Table III: Solubility of propyl gallate.


Solvent Solubility at 208C unless otherwise stated
Almond oil 1 in 44
Castor oil 1 in 4.5
Cottonseed oil 1 in 81 at 308C
Ethanol (95%) 1 in 3
1 in 0.98 at 258C
Ether 1 in 3
1 in 1.2 at 258C
Lanolin 1 in 16.7 at 258C
Lard 1 in 88 at 458C
Mineral oil 1 in 200
Peanut oil 1 in 2000
Propylene glycol 1 in 2.5 at 258C
Soybean oil 1 in 100 at 258C
Water 1 in 1000
1 in 286 at 258C

Solvent Solubility at 208C unless otherwise stated


Chloroform Practically insoluble
Ethanol (95%) Very slightly soluble
Ether Practically insoluble
Water 1 in 1.6
1 in 1.3 at 758C

Solubility Soluble 1 in 3.5 parts of water at 208C; 1 in 2 parts of


water at 1008C; and 1 in 70 parts of ethanol (95%). Freely
soluble in glycerol. Aqueous solution is acidic.

Solubility Freely soluble in water; slightly soluble in ethanol,


chloroform, ether and benzene

Solvent Solubility at 208C unless otherwise stated


Ethanol (95%) Slightly soluble
Glycerin Freely soluble
Water 1 in 1.9
1 in 1.2 at 1008C

Solubility Soluble 1 in 3.2 parts of water; soluble in glycerin;


practically insoluble in ethanol (95%).

Solubility Soluble in water; practically insoluble in ethanol


(95%).

Solvent Solubility at 208C unless otherwise stated


Chloroform Soluble
Ethanol 95% 1 in 4
Ether Soluble
Methanol 1 in 3
Water 1 in 5.7 at 08C
1 in 8.4 at 158C
1 in 11.8 at 258C
1 in 15.6 at 358C

Solubility Soluble 1 in 1.5 parts of ethanol (95%) and 1 in less


than 1 part of water; sparingly soluble in ether.

Solvent Solubility at 208C unless otherwise stated


Chloroform Practically insoluble
Ethanol (95%) 1 in 2.5
Ether 1 in 250
Glycerin Soluble
Methanol 1 in 1.7
Propan-1-ol 1 in 10.5
Water 1 in 0.75
1 in 0.5 at 1008C

Solubility Soluble 1 in 0.71.0 of chloroform; 1 in 1 of ethanol


(95%); 1 in 1.5 of ether, glacial acetic acid; 1 in 1.72.0 of olive
oil; 1 in 1000 of water. Freely soluble in essential oils, fixed oils,
and fats. Sparingly soluble in glycerin. Dissolves in dilute
solutions of alkali hydroxides, forming salts that have increased
solubility but whose solutions darken on standing

Vitamin E Polyethylene Glycol Succinate


Solubility Miscible in water in all parts.(1)

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